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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4wecNADShort chain dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4wecNADShort chain dehydrogenase/1.000
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.542
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.537
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.537
1b2lNDCAlcohol dehydrogenase1.1.1.10.535
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.531
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.526
4esoNAPPutative oxidoreductase/0.525
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.524
1vyrFMNPentaerythritol tetranitrate reductase/0.518
3lqfNADGalactitol dehydrogenase/0.515
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.513
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.511
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.511
1xe55FEPlasmepsin-23.4.23.390.510
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.509
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.508
4dbzNDPPutative ketoacyl reductase1.3.10.507
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.506
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/0.506
3otwCOAPhosphopantetheine adenylyltransferase/0.505
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.504
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.504
4ipw1G7Mycocyclosin synthase1.14.21.90.500
1bwsNDPGDP-L-fucose synthase/0.499
2vkeTACTetracycline repressor protein class D/0.499
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.499
2g1n1IGRenin3.4.23.150.498
1h50FMNPentaerythritol tetranitrate reductase/0.496
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.495
3p8jFMNPentaerythritol tetranitrate reductase/0.495
2xyuQ9GEphrin type-A receptor 42.7.10.10.494
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.494
2iko7IGRenin3.4.23.150.493
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.492
2uxoTACHTH-type transcriptional regulator TtgR/0.492
2oapANPType II secretion system protein (GspE-2)/0.491
2rlcCHDCholoylglycine hydrolase3.5.1.240.491
3u9eCOALmo1369 protein/0.491
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.490
2ft9CHDFatty acid-binding protein 2, liver/0.490
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.490
1tllFMNNitric oxide synthase, brain1.14.13.390.488
3f03FMNPentaerythritol tetranitrate reductase/0.488
4dc0NDPPutative ketoacyl reductase1.3.10.488
4g7gVFVLanosterol 14-alpha-demethylase/0.488
1xe65FPPlasmepsin-23.4.23.390.487
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.487
3p62FMNPentaerythritol tetranitrate reductase/0.487
4b79NADProbable short-chain dehydrogenase/0.487
2fj1CTCTetracycline repressor protein class D/0.486
3gw9VNILanosterol 14-alpha-demethylase/0.486
4gk3L87Ephrin type-A receptor 32.7.10.10.486
4oqyNDP(S)-imine reductase/0.485
1h51FMNPentaerythritol tetranitrate reductase/0.484
1tehNADAlcohol dehydrogenase class-31.1.1.10.484
2aa3AP0L-lactate dehydrogenase/0.484
2ejvNADL-threonine 3-dehydrogenase/0.484
3e8xNAPBH1520 protein/0.484
4k6fNAPPutative Acetoacetyl-CoA reductase/0.484
1mp0NADAlcohol dehydrogenase class-31.1.1.10.483
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.483
3ibqATPPyridoxal kinase/0.483
3r9uFADThioredoxin reductase/0.483
2iyfERYOleandomycin glycosyltransferase2.4.10.482
5a3bAPRSIR2 family protein/0.481
2xpuTDCTetracycline repressor protein class D/0.480
1f8fNADBenzyl alcohol dehydrogenase/0.479
1m13HYFNuclear receptor subfamily 1 group I member 2/0.479
3p84FMNPentaerythritol tetranitrate reductase/0.479
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.479
4yaiNAIC alpha-dehydrogenase/0.479
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.479
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.478
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.477
4ips1G4Mycocyclosin synthase1.14.21.90.477
4jicFMNGTN Reductase/0.477
4v2gITCTetracycline repressor protein class D/0.477
2abbFMNPentaerythritol tetranitrate reductase/0.476
2gv8NDPThiol-specific monooxygenase1.14.130.476
2ql6ADPNicotinamide riboside kinase 1/0.476
3qt62P0Mevalonate diphosphate decarboxylase/0.476
4nbwNADShort-chain dehydrogenase/reductase SDR/0.476
1g1aNADdTDP-glucose 4,6-dehydratase/0.475
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.475
2o12FMNChorismate synthase/0.475
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.475
3d4pNADL-lactate dehydrogenase 11.1.1.270.475
3p74FMNPentaerythritol tetranitrate reductase/0.475
4u7wNDPMxaA/0.475
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.474
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.474
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.474
2g263LGRenin3.4.23.150.474
2gjlFMNNitronate monooxygenase1.13.12.160.474
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.473
2he5NDPAldo-keto reductase family 1 member C211.1.10.473
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3p82FMNPentaerythritol tetranitrate reductase/0.473
4egbNADdTDP-glucose 4,6-dehydratase/0.473
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.473
2ejzSAHDiphthine synthase/0.472
2vbdV10Isopenicillin N synthase1.21.3.10.472
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
3vyfVYFRenin3.4.23.150.471
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.470
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.470
2y3rTRKTamL/0.470
3orfNADDihydropteridine reductase1.5.1.340.470
3vyeVYERenin3.4.23.150.470
4cukNAID-lactate dehydrogenase/0.470
1bil0IURenin3.4.23.150.469
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.469
4bfxZVXPantothenate kinase2.7.1.330.469
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.469
4yaoFMNNADPH--cytochrome P450 reductase/0.469
2j83BATUlilysin3.4.240.468
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.468
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3u8l09QAcetylcholine-binding protein/0.468
4a81DXCMajor pollen allergen Bet v 1-A/0.468
1e3eNAIAlcohol dehydrogenase 41.1.1.10.467
1h63FMNPentaerythritol tetranitrate reductase/0.467
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.467
1lbcCYZGlutamate receptor 2/0.467
2g1s4IGRenin3.4.23.150.467
2y3sTIRTamL/0.467
2yxuATPPyridoxal kinase2.7.1.350.467
3w8eNAD3-hydroxybutyrate dehydrogenase/0.467
4cdmFO1Deoxyribodipyrimidine photolyase/0.467
4fryNADPutative signal-transduction protein with CBS domains/0.467
1dhrNADDihydropteridine reductase1.5.1.340.466
3gfbNADL-threonine 3-dehydrogenase/0.466
4a6rTA8Probable aminotransferase/0.466
4ejvLCLTranscriptional regulator TcaR/0.466
4m83ERYOleandomycin glycosyltransferase2.4.10.466
4q71FADBifunctional protein PutA/0.466
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.466
4zj8SUVOrexin receptor type 1/0.466
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.465
1kp2ATPArgininosuccinate synthase6.3.4.50.465
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.465
2a7r5GPGMP reductase 2/0.465
2fs4PZ1Renin3.4.23.150.465
2qenADPWalker-Type ATPase/0.465
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.465
3lsiFADPyranose 2-oxidase/0.465
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.465
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
1u3dFADCryptochrome-1/0.464
1x1aSAMC-20 methyltransferase/0.464
4ambDUDPutative glycosyl transferase/0.464
4g3jVNTLanosterol 14-alpha-demethylase/0.464
4nmdFDABifunctional protein PutA/0.464
4q73FADBifunctional protein PutA/0.464
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.463
1h60STRPentaerythritol tetranitrate reductase/0.463
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.463
2z1mNDPGDP-mannose 4,6-dehydratase/0.463
2zbaZBATrichothecene 3-O-acetyltransferase/0.463
1hdrNADDihydropteridine reductase1.5.1.340.462
1o9bNAIQuinate/shikimate dehydrogenase/0.462
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.462
2qbmCAMCamphor 5-monooxygenase1.14.15.10.462
2qo9ANPEphrin type-A receptor 32.7.10.10.462
3kp4MIITranscriptional regulator TcaR/0.462
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.462
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.462
4xguADPPutative pachytene checkpoint protein 2/0.462
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.461
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.461
3h3qH13Collagen type IV alpha-3-binding protein/0.461
4a83DXCMajor pollen allergen Bet v 1-A/0.461
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.461
4kbyC2EStimulator of interferon genes protein/0.461
4xr9NADCalS8/0.461
1j5pNADL-aspartate dehydrogenase1.4.1.210.460
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.460
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.460
1nzdUPGDNA beta-glucosyltransferase/0.460
2ahrNAPPyrroline-5-carboxylate reductase/0.460
3gwfFADCyclohexanone monooxygenase/0.460
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
3oibFDAPutative acyl-CoA dehydrogenase/0.460
3v2uATPProtein GAL3/0.460
4ure1PSCyclohexanol dehydrogenase/0.460
5cwa0GAAnthranilate synthase component 14.1.3.270.460
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.459
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1w6hTITPlasmepsin-23.4.23.390.459
2ntrL00Beta-secretase 13.4.23.460.459
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.459
2vkvTDCTetracycline repressor protein class D/0.459
3f63GTXGlutathione transferase GST1-4/0.459
3fr4F8AFatty acid-binding protein, adipocyte/0.459
3h3t16HCollagen type IV alpha-3-binding protein/0.459
3tjzGNPADP-ribosylation factor 1/0.459
4qxq1YEStimulator of interferon genes protein/0.459
1obnASVIsopenicillin N synthase1.21.3.10.458
1rfvADPPyridoxal kinase2.7.1.350.458
2g1o2IGRenin3.4.23.150.458
2g247IGRenin3.4.23.150.458
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.458
2xfsJ01Uncharacterized protein/0.458
2y4gTIRTamL/0.458
3gkaFMNN-ethylmaleimide reductase/0.458
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
4du82P0Mevalonate diphosphate decarboxylase/0.458
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.458
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
2qw034Z4-chlorobenzoyl CoA ligase/0.457
3zoiM2WIsopenicillin N synthase1.21.3.10.457
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.457
4uocNCNCinA-like protein/0.457
1i59ANPChemotaxis protein CheA2.7.13.30.456
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1kkq471Peroxisome proliferator-activated receptor alpha/0.456
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.456
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1udaUFGUDP-glucose 4-epimerase5.1.3.20.456
2g1y5IGRenin3.4.23.150.456
2xviFADPutative flavin-containing monooxygenase/0.456
3ctyFADProbable thioredoxin reductase/0.456
3junAKDPhenazine biosynthesis protein A/B/0.456
4bb3KKAIsopenicillin N synthase1.21.3.10.456
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4o8aFADBifunctional protein PutA1.2.1.880.456
4rww2BALmo2692 protein/0.456
5a9sNAPPutative dehydrogenase/0.456
1h74ADPHomoserine kinase2.7.1.390.455
1nooCAHCamphor 5-monooxygenase1.14.15.10.455
1xddAAYIntegrin alpha-L/0.455
2bjfDXCCholoylglycine hydrolase3.5.1.240.455
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.455
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
3junAJDPhenazine biosynthesis protein A/B/0.455
3pcrGTPADP-ribosylation factor 6/0.455
4b1rITCTetracycline repressor protein class D/0.455
4fdaNAP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.455
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.455
4qxr1YEStimulator of interferon genes protein/0.455
5d3qGDPDynamin-13.6.5.50.455
5hs1VORLanosterol 14-alpha demethylase/0.455
5jy1NADPutative short-chain dehydrogenase/reductase/0.455
1eioGCHGastrotropin/0.454
1hb1OCVIsopenicillin N synthase1.21.3.10.454
1l7x700Glycogen phosphorylase, liver form2.4.1.10.454
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.454
2d29FADAcyl-CoA dehydrogenase/0.454
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.454
2il2LIXRenin3.4.23.150.454
2lbaCHOFatty acid binding protein 6/0.454
2qboCAMCamphor 5-monooxygenase1.14.15.10.454
3w6hAZMCarbonic anhydrase 14.2.1.10.454
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.454
4ejmNAPPutative zinc-binding dehydrogenase/0.454
4fxy0W2Neurolysin, mitochondrial3.4.24.160.454
1ha3MAUElongation factor Tu-A/0.453
1hb3SCVIsopenicillin N synthase1.21.3.10.453
2bi4NADLactaldehyde reductase1.1.1.770.453
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.453
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3l63CAMCamphor 5-monooxygenase1.14.15.10.453
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.453
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.453
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1u3cFADCryptochrome-1/0.452
1u4oNDDL-lactate dehydrogenase1.1.1.270.452
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2gevCOKPantothenate kinase2.7.1.330.452
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.452
2ignFADPyranose 2-oxidase/0.452
2vwqNAPGlucose 1-dehydrogenase/0.452
3dds26BGlycogen phosphorylase, liver form2.4.1.10.452
3gwfNAPCyclohexanone monooxygenase/0.452
3p67FMNPentaerythritol tetranitrate reductase/0.452
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.452
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.452
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.452
4jx1CAHCamphor 5-monooxygenase1.14.15.10.452
4loi1YCStimulator of interferon genes protein/0.452
1fm4DXCMajor pollen allergen Bet v 1-L/0.451
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.451
2iviACWIsopenicillin N synthase1.21.3.10.451
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.451
3a0tADPSensor histidine kinase/0.451
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.451
3vsxR32Renin3.4.23.150.451
4r20AERCytochrome P450 family 17 polypeptide 2/0.451
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
2a94AP0L-lactate dehydrogenase1.1.1.270.450
2geuCOKPantothenate kinase2.7.1.330.450
2ohvNHLGlutamate racemase/0.450
2yoj8Y6Genome polyprotein2.7.7.480.450
2zcvNDPQuinone oxidoreductase 21.6.5.20.450
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.450
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.450
3k4nFADPyranose 2-oxidase/0.450
3keuATPPyridoxal kinase2.7.1.350.450
3s1dZIRCytokinin dehydrogenase 11.5.99.120.450
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.450
4q0kGA3Phytohormone-binding protein/0.450
4xj43ATCyclic GMP-AMP synthase/0.450
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.450
1dirNADDihydropteridine reductase1.5.1.340.449
1g6kNADGlucose 1-dehydrogenase1.1.1.470.449
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1icsFMN12-oxophytodienoate reductase 11.3.1.420.449
1jioDEB6-deoxyerythronolide B hydroxylase/0.449
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.449
1o76CAMCamphor 5-monooxygenase1.14.15.10.449
1x7hNDPPutative ketoacyl reductase1.3.10.449
1yb5NAPQuinone oxidoreductase1.6.5.50.449
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.449
2o4cNADErythronate-4-phosphate dehydrogenase/0.449
2rqfJH3Hemolymph juvenile hormone binding protein/0.449
3h0bB35Beta-secretase 13.4.23.460.449
3h3r14HCollagen type IV alpha-3-binding protein/0.449
3h3sH15Collagen type IV alpha-3-binding protein/0.449
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
3p2oNADBifunctional protein FolD/0.449
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.449
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.449
3wqmB29Diterpene synthase3.1.7.80.449
4bfzZVZPantothenate kinase2.7.1.330.449
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.449
4j7xNAPSepiapterin reductase1.1.1.1530.449
1fk8NAD3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase1.1.1.500.448
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.448
1psa0ZLPepsin A3.4.23.10.448
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.448
1zrzBI1Protein kinase C iota type2.7.11.130.448
2b58COADiamine acetyltransferase 1/0.448
2dftADPShikimate kinase2.7.1.710.448
2ikuLIYRenin3.4.23.150.448
2po7CHDFerrochelatase, mitochondrial4.99.1.10.448
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
2vn0TDZCytochrome P450 2C8/0.448
2x9dITCTetracycline repressor protein class D/0.448
3b6pTMPThree-prime repair exonuclease 13.1.11.20.448
3fwjCAMCamphor 5-monooxygenase1.14.15.10.448
3iocA5DPantothenate synthetase6.3.2.10.448
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.448
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.448
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.448
3mx5UTPNucleoprotein/0.448
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.448
4dptAGSMevalonate diphosphate decarboxylase/0.448
4eb7PLPCysteine desulfurase IscS 2/0.448
4pghSAMCaffeic acid O-methyltransferase/0.448
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1ma0NADAlcohol dehydrogenase class-31.1.1.10.447
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.447
1q23FUAChloramphenicol acetyltransferase2.3.1.280.447
1rd7FOLDihydrofolate reductase1.5.1.30.447
1rneC60Renin3.4.23.150.447
1v9aSAHUncharacterized protein/0.447
2a92NAIL-lactate dehydrogenase/0.447
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
3adaNADSubunit alpha of sarocosine oxidase/0.447
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.447
3isjA8DPantothenate synthetase6.3.2.10.447
3nl6TPSUncharacterized protein/0.447
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
3uylTYDProbable NDP-rhamnosyltransferase/0.447
4bfvZVVPantothenate kinase2.7.1.330.447
4enhFVXCholesterol 24-hydroxylase/0.447
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.447
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.447
4gddNAIUDP-galactopyranose mutase/0.447
4itmATPTetraacyldisaccharide 4'-kinase/0.447
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.447
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.447
1kh3ANPArgininosuccinate synthase/0.446
1pjcNADAlanine dehydrogenase/0.446
1t85CAMCamphor 5-monooxygenase1.14.15.10.446
1ykdCMPAdenylate cyclase/0.446
3fp0FP015-O-acetyltransferase/0.446
3oetNADErythronate-4-phosphate dehydrogenase/0.446
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.446
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4a84DXCMajor pollen allergen Bet v 1-A/0.446
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.446
4qnwFMNChanoclavine-I aldehyde reductase easA/0.446
5kwvANPPantothenate synthetase/0.446
1bk0ACVIsopenicillin N synthase1.21.3.10.445
1p0pBCHCholinesterase3.1.1.80.445
2npxNADNADH peroxidase1.11.1.10.445
3fhyATPPyridoxal kinase2.7.1.350.445
3g5hYTTMycocyclosin synthase1.14.21.90.445
3ge1ADPGlycerol kinase/0.445
3ig6438Urokinase-type plasminogen activator3.4.21.730.445
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
4dpy2P0Mevalonate diphosphate decarboxylase/0.445
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.445
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.445
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.445
4yxm2BADNA integrity scanning protein DisA/0.445
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.445
1bsvNDPGDP-L-fucose synthase/0.444
1kvkATPMevalonate kinase2.7.1.360.444
1ur5NADMalate dehydrogenase/0.444
1w4zNAPPutative ketoacyl reductase1.3.10.444
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.444
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.444
3b6zCO7Enoyl reductase LovC10.444
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ijoB4DGlutamate receptor 2/0.444
3wrjCAMCamphor 5-monooxygenase1.14.15.10.444
4df2FMNNADPH dehydrogenase/0.444
4ead0NPThymidine phosphorylase2.4.2.40.444
4kwhNAPReductase homolog/0.444
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.444
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.443
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.443
2c29NAPDihydroflavonol 4-reductase/0.443
2freFMNNAD(P)H-flavin oxidoreductase/0.443
2g1r3IGRenin3.4.23.150.443
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.443
2y6o1N1Ephrin type-A receptor 42.7.10.10.443
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.443
3fr28CAFatty acid-binding protein, adipocyte/0.443
3juqAJDPhenazine biosynthesis protein A/B/0.443
3mlaJJZProbable nicotinate-nucleotide adenylyltransferase/0.443
3qe2FMNNADPH--cytochrome P450 reductase/0.443
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4cd2FOLDihydrofolate reductase1.5.1.30.443
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.443
4l4eCAMCamphor 5-monooxygenase1.14.15.10.443
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.443
4lt63ATPoly(A) polymerase gamma2.7.7.190.443
4y9uNAPNADPH--cytochrome P450 reductase/0.443
5cyoGDPSeptin-9/0.443
1fmlRTLRetinol dehydratase/0.442
1qorNDPQuinone oxidoreductase 1/0.442
1rfuADPPyridoxal kinase2.7.1.350.442
1yw8A75Methionine aminopeptidase 2/0.442
2abaSTRPentaerythritol tetranitrate reductase/0.442
2cy0NAPShikimate dehydrogenase (NADP(+))/0.442
2g20L1ARenin3.4.23.150.442
2g21L1BRenin3.4.23.150.442
2zsiGA4Gibberellin receptor GID1A30.442
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3gvhNADMalate dehydrogenase/0.442
3h4vNAPPteridine reductase 11.5.1.330.442
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3nutSAHPrecorrin-3 methylase/0.442
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.442
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.442
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.442
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.442
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.441
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.441
1tqf32PBeta-secretase 13.4.23.460.441
1zemNADXylitol dehydrogenase/0.441
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.441
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.441
2yj5ATPCopper-transporting ATPase/0.441
2zshGA3Gibberellin receptor GID1A30.441
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.441
3atzFMNProstaglandin F2a synthase/0.441
3fwgCAMCamphor 5-monooxygenase1.14.15.10.441
3hl0NADMaleylacetate reductase/0.441
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.441
3wswNADL-lactate dehydrogenase/0.441
3zkyWT4Isopenicillin N synthase1.21.3.10.441
4fcr0TMHeat shock protein HSP 90-alpha/0.441
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4iah1DXAlr2278 protein/0.441
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.440
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.440
1cjtFOKAdenylate cyclase type 2/0.440
1cjtFOKAdenylate cyclase type 5/0.440
1fxsNAPGDP-L-fucose synthase/0.440
1i5eU5PUracil phosphoribosyltransferase/0.440
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.440
1r2jFADFkbI/0.440
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.440
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.440
2igoFADPyranose 2-oxidase/0.440
2ij7TPFMycocyclosin synthase1.14.21.90.440
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.440
2rirNAPDipicolinate synthase subunit A/0.440
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.440
3af3GCPPantothenate kinase2.7.1.330.440
3co93MSGenome polyprotein2.7.7.480.440
3ieuGDPGTPase Era/0.440
3p5pA3CTaxadiene synthase4.2.3.170.440
3sx2NADUncharacterized protein/0.440
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.440
4blrUTPNTPase P4/0.440
4g090VDHistidinol dehydrogenase/0.440
4g48PZBMycocyclosin synthase1.14.21.90.440
4p63NADProbable deoxyhypusine synthase2.5.1.460.440
4p9dTMPDeoxycytidylate deaminase/0.440
4psbGA3Cytokinin-specific binding protein/0.440
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.440