sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dlv | GNP | GTPase HRas |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4dlv | GNP | GTPase HRas | / | 1.000 | |
| 2rgc | GNP | GTPase HRas | / | 0.908 | |
| 4dlx | GNP | GTPase HRas | / | 0.899 | |
| 4dlz | GNP | GTPase HRas | / | 0.868 | |
| 3rs5 | GNP | GTPase HRas | / | 0.862 | |
| 2rgb | GNP | GTPase HRas | / | 0.832 | |
| 3rs0 | GNP | GTPase HRas | / | 0.818 | |
| 2rge | GNP | GTPase HRas | / | 0.817 | |
| 4dlw | GNP | GTPase HRas | / | 0.817 | |
| 3rsl | GNP | GTPase HRas | / | 0.787 | |
| 3oiv | GNP | GTPase HRas | / | 0.776 | |
| 3v4f | GNP | GTPase HRas | / | 0.775 | |
| 3rs7 | GNP | GTPase HRas | / | 0.752 | |
| 3lbn | GNP | GTPase HRas | / | 0.743 | |
| 3k8y | GNP | GTPase HRas | / | 0.699 | |
| 3ddc | GNP | GTPase HRas | / | 0.696 | |
| 4nyi | GNP | GTPase HRas | / | 0.671 | |
| 2c5l | GTP | GTPase HRas | / | 0.670 | |
| 4l9w | GNP | GTPase HRas | / | 0.665 | |
| 4dls | GNP | GTPase HRas | / | 0.661 | |
| 3l8y | GNP | GTPase HRas | / | 0.660 | |
| 3i3s | GNP | GTPase HRas | / | 0.654 | |
| 3oiu | GNP | GTPase HRas | / | 0.651 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.645 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.639 | |
| 5b2z | GNP | GTPase HRas | / | 0.639 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.636 | |
| 3oiw | GNP | GTPase HRas | / | 0.634 | |
| 4dsn | GCP | GTPase KRas | / | 0.632 | |
| 4g0n | GNP | GTPase HRas | / | 0.631 | |
| 3kud | GDP | GTPase HRas | / | 0.628 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.627 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.626 | |
| 4k81 | GTP | GTPase HRas | / | 0.623 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.618 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.615 | |
| 4nyj | GNP | GTPase HRas | / | 0.612 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.612 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.610 | |
| 4l9s | GDP | GTPase HRas | / | 0.610 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.605 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.600 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.600 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.598 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.593 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.591 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.586 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.586 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.585 | |
| 4dlt | GNP | GTPase HRas | / | 0.584 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.582 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.581 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.581 | |
| 4mit | GTP | Rho-related protein racC | / | 0.581 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.580 | |
| 3lbh | GNP | GTPase HRas | / | 0.579 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.578 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.578 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.574 | |
| 3rs4 | GNP | GTPase HRas | / | 0.574 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.573 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.573 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.570 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.569 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.567 | |
| 4epw | GDP | GTPase KRas | / | 0.567 | |
| 4tq9 | GDP | GTPase KRas | / | 0.566 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.565 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.565 | |
| 4l8g | GDP | GTPase KRas | / | 0.565 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.563 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.561 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.560 | |
| 4obe | GDP | GTPase KRas | / | 0.560 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.559 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.558 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.558 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.557 | |
| 4lv6 | GDP | GTPase KRas | / | 0.557 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.555 | |
| 4dso | GSP | GTPase KRas | / | 0.555 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.555 | |
| 4ldj | GDP | GTPase KRas | / | 0.554 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.553 | |
| 3wyg | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.553 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.552 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.548 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.547 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.547 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.546 | |
| 4q02 | GDP | GTPase KRas | / | 0.546 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.544 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.543 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.541 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.541 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.540 | |
| 4xvq | GNP | GTPase HRas | / | 0.540 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.539 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.538 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.538 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.538 | |
| 3tgp | GNP | GTPase HRas | / | 0.537 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.537 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.537 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.535 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.535 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.534 | |
| 2rgg | GNP | GTPase HRas | / | 0.534 | |
| 4wa7 | GDP | GTPase KRas | / | 0.534 | |
| 4epx | GDP | GTPase KRas | / | 0.532 | |
| 4ql3 | GDP | GTPase KRas | / | 0.532 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.531 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.529 | |
| 4luc | GDP | GTPase KRas | / | 0.529 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.529 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.528 | |
| 4lpk | GDP | GTPase KRas | / | 0.527 | |
| 3lbi | GNP | GTPase HRas | / | 0.526 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.525 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.524 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.523 | |
| 1lfd | GNP | GTPase HRas | / | 0.521 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.521 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.521 | |
| 4xvr | GNP | GTPase HRas | / | 0.520 | |
| 2ce2 | GDP | GTPase HRas | / | 0.519 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.519 | |
| 4q03 | GDP | GTPase KRas | / | 0.518 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.516 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.515 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.515 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.514 | |
| 4lrw | GDP | GTPase KRas | / | 0.514 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.513 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.513 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.512 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.510 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.510 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.509 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.509 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.509 | |
| 2mse | GNP | MHC class I alpha chain | / | 0.507 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.506 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.504 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.503 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.502 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.501 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.500 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.499 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.499 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.497 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.496 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.495 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.494 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.494 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.493 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.493 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.493 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.493 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.493 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.493 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.492 | |
| 2cl6 | CAG | GTPase HRas | / | 0.491 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.490 | |
| 4dsu | GDP | GTPase KRas | / | 0.490 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.490 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.489 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.487 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.487 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.486 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.484 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.484 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.484 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.483 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.483 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.482 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.482 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.482 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.482 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.481 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.481 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.481 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.481 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.480 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.480 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.480 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.480 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.480 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.479 | |
| 3k9l | GNP | GTPase HRas | / | 0.479 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.479 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.478 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.478 | |
| 2xau | ADP | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 | 3.6.4.13 | 0.476 | |
| 1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.475 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.475 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.475 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.475 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.475 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.475 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.474 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.474 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.473 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.473 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.473 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.473 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.473 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.473 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.472 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.472 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.472 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.472 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.472 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.471 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.471 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.470 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.470 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.470 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.470 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.470 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.470 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.470 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.470 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.470 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.470 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.470 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.470 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.470 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.469 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.469 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.469 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.469 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.469 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.468 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.468 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.468 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.468 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.468 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.468 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.468 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.468 | |
| 4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.468 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.467 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.466 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.466 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.466 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.466 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.466 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.465 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.465 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.465 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.465 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.464 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.464 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.464 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.464 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.464 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.464 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.463 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.463 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.463 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.463 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.463 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.462 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.462 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.462 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.462 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.462 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.462 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.462 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.462 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.462 | |
| 3nkt | 1HN | Gentisate 1,2-dioxygenase | / | 0.462 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.462 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.461 | |
| 2vcq | D25 | Hematopoietic prostaglandin D synthase | / | 0.461 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.461 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.461 | |
| 4ehv | 0SJ | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.461 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.461 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.461 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.460 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.460 | |
| 3v49 | PK0 | Androgen receptor | / | 0.460 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.460 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.459 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.459 | |
| 3kro | IPE | Geranyl diphosphate synthase large subunit | / | 0.459 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.459 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.459 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.458 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.458 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.457 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2r8o | T5X | Transketolase 1 | / | 0.457 | |
| 2vk8 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.457 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.457 | |
| 4nte | FAD | DepH | / | 0.457 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.456 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.456 | |
| 2vcw | ZZA | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.456 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.456 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.456 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.456 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.456 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.456 | |
| 4yvn | EBS | Spore coat protein A | / | 0.456 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.455 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.455 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.455 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.455 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.455 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4edz | 0O5 | Hematopoietic prostaglandin D synthase | / | 0.455 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.455 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.455 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.454 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.454 | |
| 4l8u | 9AZ | Serum albumin | / | 0.454 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.454 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.453 | |
| 1mbz | IOT | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.453 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.453 | |
| 1ysi | N3B | Bcl-2-like protein 1 | / | 0.453 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.453 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.453 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.453 | |
| 3pfh | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.453 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.453 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.453 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.453 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.453 | |
| 1gm8 | SOX | Penicillin G acylase | 3.5.1.11 | 0.452 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.452 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.452 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.452 | |
| 3eku | CY9 | Actin-5C | / | 0.452 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.452 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.452 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.452 | |
| 4l2x | YL2 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.452 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.452 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.452 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.451 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.451 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.451 | |
| 1wuq | 8GT | GTP cyclohydrolase 1 | / | 0.451 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.451 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.451 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.451 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2wu2 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.451 | |
| 2wu2 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.451 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.451 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4ao4 | PLK | Beta-transaminase | / | 0.451 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.451 | |
| 4lut | DCS | Alanine racemase | / | 0.451 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.451 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.451 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.451 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1wy7 | SAH | Uncharacterized protein | / | 0.450 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.450 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.450 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.450 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.450 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 2zpa | ADP | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.450 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.450 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.450 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.450 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.450 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.450 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.450 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.450 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.450 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.449 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.449 | |
| 1u3q | 272 | Estrogen receptor beta | / | 0.449 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.449 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.449 | |
| 3eks | CY9 | Actin-5C | / | 0.449 | |
| 3iaa | TYD | CalG2 | / | 0.449 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.449 | |
| 3rga | ILD | Epoxide hydrolase LasB | 5.5.1 | 0.449 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.449 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.449 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.449 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.448 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.448 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.448 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.448 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.448 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.448 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.448 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.448 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.448 | |
| 3n3b | FMN | Protein NrdI | / | 0.448 | |
| 3px2 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.448 | |
| 3q1f | YPP | Beta-lactamase | / | 0.448 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.448 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.447 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.447 | |
| 1n5t | OAL | ActVA 6 protein | / | 0.447 | |
| 1wnz | 2VA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.447 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.447 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.447 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.447 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.447 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.447 | |
| 5jqg | GTP | Tubulin alpha-1B chain | / | 0.447 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.446 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2mt9 | FMN | Flavodoxin 2 | / | 0.446 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.446 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.446 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4ge1 | TSS | Biogenic amine-binding protein | / | 0.446 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.446 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.446 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.446 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2g72 | F21 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.445 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.445 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.445 | |
| 2yxj | N3C | Bcl-2-like protein 1 | / | 0.445 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.445 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.445 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.444 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.444 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2bzg | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.444 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.444 | |
| 2rto | IMI | Streptavidin | / | 0.444 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.444 | |
| 3e6e | DCS | Alanine racemase | / | 0.444 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3zfd | ANP | Chromosome-associated kinesin KIF4 | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.444 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.444 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.444 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.444 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.444 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.443 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.443 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.443 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.443 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.443 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.443 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.443 | |
| 2r8p | T6F | Transketolase 1 | / | 0.443 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.443 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.443 | |
| 4fx2 | FMN | Flavodoxin | / | 0.443 | |
| 4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.443 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.443 | |
| 4zo3 | C6L | Acylhomoserine lactonase | / | 0.443 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.442 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.442 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1m9a | GTX | Glutathione S-transferase class-mu 26 kDa isozyme | 2.5.1.18 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1wdk | ACO | 3-ketoacyl-CoA thiolase | / | 0.442 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2p3q | SAH | Genome polyprotein | / | 0.442 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.442 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.442 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.442 | |
| 3pz4 | 3PZ | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 3tr9 | PT1 | Dihydropteroate synthase | / | 0.442 | |
| 3up0 | D7S | aceDAF-12 | / | 0.442 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.442 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.442 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.441 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.441 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.441 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.441 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.441 | |
| 2rtq | IMI | Streptavidin | / | 0.441 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.441 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 2zsc | BTN | Tamavidin2 | / | 0.441 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.441 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.441 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.441 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.441 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.441 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.441 | |
| 4nu0 | AP5 | Adenylate kinase | / | 0.441 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1jx2 | ADP | Myosin-2 heavy chain | / | 0.440 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1onp | FOM | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.440 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.440 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.440 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
| 1x7j | GEN | Estrogen receptor beta | / | 0.440 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 2qll | PLP | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.440 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3tyd | XHP | Dihydropteroate synthase | / | 0.440 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.440 |