sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3m34 | TPP | Transketolase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3m34 | TPP | Transketolase | / | 1.000 | |
| 3m7i | TPP | Transketolase | / | 0.670 | |
| 4c7x | TPP | Transketolase | / | 0.573 | |
| 3m6l | TPP | Transketolase | / | 0.542 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.515 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.496 | |
| 3oq6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.486 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.485 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.484 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.483 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.483 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.482 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.482 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.482 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.481 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 2w03 | ADN | AcsD | / | 0.481 | |
| 3gue | UPG | UTP-glucose-1-phosphate uridylyltransferase 2, putative | / | 0.481 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.478 | |
| 2w02 | ATP | AcsD | / | 0.478 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.478 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.477 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.475 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.475 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.474 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.474 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.473 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.473 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.473 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.473 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.473 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.473 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.473 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.472 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.472 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.472 | |
| 4iah | 1DX | Alr2278 protein | / | 0.472 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.471 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.471 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.471 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.470 | |
| 3rr3 | FLR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.470 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.469 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.468 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.468 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.468 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.468 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.468 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.467 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1s7n | COA | Acetyl transferase | / | 0.466 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.466 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.466 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.465 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.465 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.465 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.464 | |
| 5dby | NPS | Serum albumin | / | 0.464 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.463 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.463 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.463 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.463 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.463 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.463 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.463 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.462 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.462 | |
| 4h1q | 0XX | Matrix metalloproteinase-9 | 3.4.24.35 | 0.462 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.462 | |
| 2vcw | ZZA | Hematopoietic prostaglandin D synthase | / | 0.461 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.461 | |
| 3l0h | GTX | Glutathione S-transferase A1 | 2.5.1.18 | 0.461 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.461 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4r3a | ANP | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.461 | |
| 5agl | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.461 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.460 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.460 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.460 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.460 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.460 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.460 | |
| 4iaw | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.460 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.460 | |
| 1fml | RTL | Retinol dehydratase | / | 0.459 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.459 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 2vku | DBE | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 4cox | IMN | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.459 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.458 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.458 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.458 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.458 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.458 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.458 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.457 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.456 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.456 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.456 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 4dwv | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.456 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.456 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.456 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.455 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.455 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.455 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.455 | |
| 3srz | UPG | Toxin A | / | 0.455 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.455 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.454 | |
| 2qiq | CYV | Replicase polyprotein 1ab | / | 0.454 | |
| 2x3j | ATP | AcsD | / | 0.454 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.454 | |
| 4jxr | ACO | Acetyltransferase | / | 0.454 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.454 | |
| 5bn3 | ADP | NEQ263 | / | 0.454 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.454 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.454 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.453 | |
| 1swg | BTN | Streptavidin | / | 0.453 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.453 | |
| 2bmb | PMM | Folic acid synthesis protein FOL1 | / | 0.453 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.453 | |
| 2mm3 | CHO | Gastrotropin | / | 0.453 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.453 | |
| 3fqk | 79Z | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.453 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.453 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.453 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1bpw | NAD | Betaine aldehyde dehydrogenase | 1.2.1.8 | 0.452 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.452 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.452 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.452 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.452 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.452 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.452 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4cf1 | IY7 | Integrase | / | 0.452 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.452 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.452 | |
| 4iae | 1DX | Alr2278 protein | / | 0.452 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.452 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.452 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.452 | |
| 1amo | NAP | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.451 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.451 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.451 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.451 | |
| 2e0i | FAD | DNA photolyase | / | 0.451 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.451 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.451 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.451 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.451 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.451 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.451 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.450 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.450 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.450 | |
| 2imk | GTX | AGAP009194-PA | / | 0.450 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.450 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.450 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3frk | TQP | QdtB | / | 0.450 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.450 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.450 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.450 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.450 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4fgr | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.450 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.450 | |
| 4hjf | C2E | GGDEF family protein | / | 0.450 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.450 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1nj5 | P5A | Proline--tRNA ligase | / | 0.449 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.449 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.449 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.449 | |
| 2puc | GUN | HTH-type transcriptional repressor PurR | / | 0.449 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands | / | 0.449 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.449 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.449 | |
| 4l8u | 9AZ | Serum albumin | / | 0.449 | |
| 4o7l | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.449 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.448 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1gsf | EAA | Glutathione S-transferase A1 | 2.5.1.18 | 0.448 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1n1d | C2G | Glycerol-3-phosphate cytidylyltransferase | 2.7.7.39 | 0.448 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.448 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.448 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4qnu | GEK | tRNA U34 carboxymethyltransferase | / | 0.448 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.448 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.447 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 2bxq | IMN | Serum albumin | / | 0.447 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.447 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.447 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.447 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.447 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.447 | |
| 3n39 | FMN | Protein NrdI | / | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.447 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 4rgq | NDP | Glycerol-1-phosphate dehydrogenase [NAD(P)+] | / | 0.447 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.447 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.447 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1lrl | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1mez | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.446 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2mji | KTR | Fatty acid-binding protein, intestinal | / | 0.446 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 2ohv | NHL | Glutamate racemase | / | 0.446 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.446 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.446 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.445 | |
| 1ei1 | ANP | DNA gyrase subunit B | / | 0.445 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.445 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.445 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2d0o | ADP | Diol dehydratase-reactivating factor alpha subunit | / | 0.445 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.445 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.445 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3h9j | APC | MccB protein | / | 0.445 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3jzm | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.445 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.445 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 4o7n | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.445 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.445 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.445 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.445 | |
| 1a2n | TET | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1c7o | PPG | Hemolysin | / | 0.444 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.444 | |
| 1o02 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2zrj | AGS | Protein RecA | / | 0.444 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.444 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.444 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.444 | |
| 3sju | NDP | Keto reductase | / | 0.444 | |
| 3vax | PLP | Uncharacterized protein | / | 0.444 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.444 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.444 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.444 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.443 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1mbz | IOT | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.443 | |
| 1mtc | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.443 | |
| 1til | ATP | Anti-sigma F factor | / | 0.443 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.443 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.443 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.443 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.443 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3nlv | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.443 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.443 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.443 | |
| 4jlo | ADP | Adenylate kinase | / | 0.443 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.443 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.443 | |
| 6cox | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 1n1e | NDE | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.442 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.442 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2dwp | ACP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.442 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.442 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.442 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.442 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.442 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.442 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.442 | |
| 5a65 | TPP | Thiamine-triphosphatase | 3.6.1.28 | 0.442 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 1tys | DHF | Thymidylate synthase | / | 0.441 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 2ejz | SAH | Diphthine synthase | / | 0.441 | |
| 2p6k | SAH | Diphthine synthase | / | 0.441 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.441 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.441 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.441 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.441 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.441 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.441 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1ols | TDP | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.440 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.440 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.440 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.440 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.440 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.440 | |
| 2zsc | BTN | Tamavidin2 | / | 0.440 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3iss | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.440 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.440 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.440 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4ko8 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.440 | |
| 4l4x | NDP | AmphI | / | 0.440 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 4rel | KMP | Glycosyltransferase | / | 0.440 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.440 |