sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2g9v | IFM | Glycogen phosphorylase, muscle form | 2.4.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2g9v | IFM | Glycogen phosphorylase, muscle form | 2.4.1.1 | 1.000 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.648 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.611 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.586 | |
| 1noi | NTZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.573 | |
| 4gpb | GFP | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.564 | |
| 4el5 | D1M | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.555 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.553 | |
| 1k08 | BZD | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.544 | |
| 2g9r | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.517 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.511 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.510 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.488 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.486 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.485 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.480 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.477 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.475 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.474 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.474 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.474 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.473 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.473 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.472 | |
| 1oon | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.472 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.471 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.470 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.470 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.470 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.469 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.469 | |
| 3onw | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.468 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.468 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4rx6 | ATP | Nitrogen regulatory PII-like protein | / | 0.468 | |
| 4z17 | PEP | Enolase | / | 0.468 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.468 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.467 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.467 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.467 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.466 | |
| 4ww0 | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.466 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.465 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.465 | |
| 3nbv | ANP | Ketohexokinase | / | 0.465 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.465 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.464 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.464 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.463 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.463 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.463 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.463 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.463 | |
| 4z36 | ON3 | Lysophosphatidic acid receptor 1 | / | 0.463 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.462 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.462 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.462 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.462 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.461 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.461 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.461 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.461 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.461 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.461 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.461 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.461 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.461 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.460 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.460 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.460 | |
| 3fro | NHF | GlgA glycogen synthase | / | 0.460 | |
| 3w8r | ACP | Uridine kinase | / | 0.460 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.459 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.459 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.459 | |
| 4wpu | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.459 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.459 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.458 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.458 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.458 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.458 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.458 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.457 | |
| 1kh2 | ATP | Argininosuccinate synthase | / | 0.457 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.457 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2e1z | B4P | Propionate kinase | / | 0.457 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.457 | |
| 2vht | ATP | NTPase P4 | / | 0.457 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.457 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.457 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.457 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.457 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.457 | |
| 4l0o | PLP | Cystathionine gamma-synthase | 2.5.1.48 | 0.457 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.456 | |
| 2ax4 | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 2.7.1.25 | 0.456 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.456 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3iaa | TYD | CalG2 | / | 0.456 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.456 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.456 | |
| 5aga | ANP | DNA polymerase theta | / | 0.456 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2e20 | B4P | Propionate kinase | / | 0.455 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.455 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.455 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.455 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.454 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.454 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.454 | |
| 2qfv | NAP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.454 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.454 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.453 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.453 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.453 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.452 | |
| 1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.452 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.452 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.452 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.452 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.452 | |
| 3ufg | ATP | Glycine--tRNA ligase alpha subunit | / | 0.452 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.452 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.452 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.451 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.451 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.451 | |
| 2dpx | GDP | GTP-binding protein RAD | / | 0.451 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.451 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.450 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.450 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.450 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.450 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.450 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.450 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.450 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.450 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.449 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.449 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.449 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.449 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.449 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.449 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.449 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.449 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.448 | |
| 2gr2 | APR | Ferredoxin reductase | / | 0.448 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.448 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3m2r | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3m2r | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.448 | |
| 3mx5 | UTP | Nucleoprotein | / | 0.448 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.448 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.448 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.448 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.448 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.448 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.448 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.447 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.447 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.447 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.446 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.446 | |
| 2clo | PLS | Tryptophan synthase beta chain | 4.2.1.20 | 0.446 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.446 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.446 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3w2l | VRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.446 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4g3s | UD1 | Bifunctional protein GlmU | / | 0.446 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.446 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.446 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.446 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.446 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.445 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.445 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.445 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.445 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3c4v | LIP | D-inositol 3-phosphate glycosyltransferase | 2.4.1.250 | 0.445 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.445 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.445 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.445 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.445 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.445 | |
| 4yau | 2AM | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.445 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.444 | |
| 1kny | APC | Kanamycin nucleotidyltransferase | 2.7.7 | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.444 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.444 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.444 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.444 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.444 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.444 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.444 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.444 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.443 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.443 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.443 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.443 | |
| 2wzw | FMN | Nitroreductase NfnB | / | 0.443 | |
| 2yqs | UD1 | UDP-N-acetylglucosamine pyrophosphorylase | 2.7.7.23 | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.443 | |
| 4bls | APC | NTPase P4 | / | 0.443 | |
| 4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.443 | |
| 1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 1ei1 | ANP | DNA gyrase subunit B | / | 0.442 | |
| 1f5n | GNP | Guanylate-binding protein 1 | / | 0.442 | |
| 1h47 | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.442 | |
| 1q3s | ADP | Thermosome subunit alpha | / | 0.442 | |
| 1qy8 | RDI | Endoplasmin | / | 0.442 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.442 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.442 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.442 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.442 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.442 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 5cyo | GDP | Septin-9 | / | 0.442 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1e2n | RCA | Thymidine kinase | / | 0.441 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.441 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.441 | |
| 1hwj | ADP | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.441 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.441 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2ad5 | ADP | CTP synthase | / | 0.441 | |
| 2e7z | MGD | Acetylene hydratase | / | 0.441 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2gr0 | ADP | Ferredoxin reductase | / | 0.441 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.441 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.441 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.441 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2d4h | 5GP | Guanylate-binding protein 1 | / | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.440 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.440 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3kbz | 2T4 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.440 | |
| 3q1f | YPP | Beta-lactamase | / | 0.440 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.440 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.440 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.440 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.440 |