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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hvxQEIQueuine tRNA-ribosyltransferase2.4.2.29

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4hvxQEIQueuine tRNA-ribosyltransferase2.4.2.291.000
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.762
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.761
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.746
2z1wBDIQueuine tRNA-ribosyltransferase2.4.2.290.704
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.703
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.676
3bllBPQQueuine tRNA-ribosyltransferase2.4.2.290.648
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.646
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.622
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.613
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.610
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.610
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.596
2bbf344Queuine tRNA-ribosyltransferase2.4.2.290.593
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.593
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.589
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.566
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.565
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.559
2qzrS79Queuine tRNA-ribosyltransferase2.4.2.290.550
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.550
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.548
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.547
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.542
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.539
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.531
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.290.528
1q65BHBQueuine tRNA-ribosyltransferase2.4.2.290.526
1q66KMBQueuine tRNA-ribosyltransferase2.4.2.290.523
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.517
1y5vNE8Queuine tRNA-ribosyltransferase2.4.2.290.510
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.505
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.502
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.498
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.290.493
4ap1NAPSteroid monooxygenase/0.493
4l2zS7MS-adenosylmethionine synthase/0.490
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.489
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.489
3zkyWT4Isopenicillin N synthase1.21.3.10.488
2vcmM11Isopenicillin N synthase1.21.3.10.487
4u0mGTPCyclic GMP-AMP synthase/0.487
3emlZMAAdenosine receptor A2a/0.487
1x8b824Wee1-like protein kinase2.7.10.20.485
2wo7ASVIsopenicillin N synthase1.21.3.10.484
5k2aZMAAdenosine receptor A2a/0.482
1bi9NADRetinal dehydrogenase 2/0.481
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.481
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.481
3fhxPXLPyridoxal kinase2.7.1.350.481
4yfy1YJVioF/0.481
5k2cZMAAdenosine receptor A2a/0.481
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.480
1uzwCDHIsopenicillin N synthase1.21.3.10.479
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.478
2b35TCLEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.477
2potGUNQueuine tRNA-ribosyltransferase2.4.2.290.477
1hfqMOTDihydrofolate reductase1.5.1.30.476
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.476
2ydoADNAdenosine receptor A2a/0.476
3new3NEMitogen-activated protein kinase 14/0.476
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
2w3aTOPDihydrofolate reductase1.5.1.30.475
3s7a684Dihydrofolate reductase1.5.1.30.475
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.475
1xzqFONtRNA modification GTPase MnmE3.6.50.474
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.474
3x2fNAIAdenosylhomocysteinase/0.473
4aosNAPSteroid monooxygenase/0.473
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.473
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.473
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.473
4ocvANPAminoglycoside phosphotransferase/0.473
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.472
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
2bu9HFVIsopenicillin N synthase1.21.3.10.471
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.471
3o9gF53Gag-Pol polyprotein/0.470
3oom507Activin receptor type-12.7.11.300.470
3s1dZIRCytokinin dehydrogenase 11.5.99.120.470
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.470
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.470
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.470
2jblSMAReaction center protein L chain/0.469
3q5kD1UHeat shock protein 83-1/0.469
4lgaA2OAbscisic acid receptor PYL2/0.469
1blzACVIsopenicillin N synthase1.21.3.10.468
1opbRETRetinol-binding protein 2/0.467
2y60M8FIsopenicillin N synthase1.21.3.10.467
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.467
5jtbZMAAdenosine receptor A2a/0.467
1dlsMTXDihydrofolate reductase1.5.1.30.466
2ptfFMNUncharacterized protein MTH_863/0.466
2qak1UNGag-Pol polyprotein3.4.23.160.466
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.466
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.466
1b2lNDCAlcohol dehydrogenase1.1.1.10.465
1lb9DNQGlutamate receptor 2/0.465
3ictADPCoenzyme A disulfide reductase/0.465
3p62FMNPentaerythritol tetranitrate reductase/0.465
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
5uviZMAAdenosine receptor A2a/0.465
1i5cADPChemotaxis protein CheA2.7.13.30.464
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.463
2vbpVB1Isopenicillin N synthase1.21.3.10.463
3ed1GA3Gibberellin receptor GID1/0.463
4f3gKAIGlutamate receptor 3/0.463
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.463
1f5fDHTSex hormone-binding globulin/0.462
2bfmTOPPteridine reductase 11.5.1.330.462
3gcq1BUMitogen-activated protein kinase 14/0.462
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.462
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.462
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.461
1kt3RTLRetinol-binding protein 4/0.461
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.461
1oc1ASVIsopenicillin N synthase1.21.3.10.461
1w1sEMUCytokinin dehydrogenase 11.5.99.120.461
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.461
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4oe2NAD2-aminomuconate 6-semialdehyde dehydrogenase/0.461
1i59ANPChemotaxis protein CheA2.7.13.30.460
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.460
2ab8MTPAdenosine kinase2.7.1.200.460
3c3dFO12-phospho-L-lactate transferase/0.460
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.460
4u7wNDPMxaA/0.460
5k2bZMAAdenosine receptor A2a/0.460
1cqp803Integrin alpha-L/0.459
2gevCOKPantothenate kinase2.7.1.330.459
2iyaZIOOleandomycin glycosyltransferase/0.459
2ykeYKEHeat shock protein HSP 90-alpha/0.459
3da24MDCarbonic anhydrase 134.2.1.10.459
3gyf51PDihydrofolate reductase1.5.1.30.459
3lfeZ84Mitogen-activated protein kinase 14/0.459
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.459
4ug7H4BNitric oxide synthase oxygenase1.14.13.1650.459
5fsxADPUncharacterized protein/0.459
1e2jTHMThymidine kinase/0.458
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2a9y26AAdenosine kinase2.7.1.200.458
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.458
2qhzMZ2Gag-Pol polyprotein/0.458
2xvv9DNSerum albumin/0.458
3b9lAZZSerum albumin/0.458
3hk1B64Fatty acid-binding protein, adipocyte/0.458
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.458
4b1fKRHGlutamate racemase/0.458
4kak06UDihydrofolate reductase1.5.1.30.458
1dr4HBIDihydrofolate reductase1.5.1.30.457
1svlADPLarge T antigen3.6.40.457
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2hk9NAPShikimate dehydrogenase (NADP(+))/0.457
2oalFADFlavin-dependent tryptophan halogenase RebH1.14.19.90.457
3qihFG7Gag-Pol polyprotein3.4.23.160.457
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.457
4j5j478Gag-Pol polyprotein3.4.23.160.457
4kwi1TJReductase homolog/0.457
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.456
2ejvNADL-threonine 3-dehydrogenase/0.456
3nxtD2EDihydrofolate reductase1.5.1.30.456
3sl2ATPSensor histidine kinase WalK/0.456
3zoiM2WIsopenicillin N synthase1.21.3.10.456
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.456
1c3eGARPhosphoribosylglycinamide formyltransferase/0.455
1dxrMSTReaction center protein L chain/0.455
1p0pBCHCholinesterase3.1.1.80.455
1qjfACSIsopenicillin N synthase1.21.3.10.455
2b7zMK1Gag-Pol polyprotein/0.455
2bxqIMNSerum albumin/0.455
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
2vbdV10Isopenicillin N synthase1.21.3.10.455
3biz61EWee1-like protein kinase2.7.10.20.455
3h4vDVPPteridine reductase 11.5.1.330.455
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
4jlk1NODeoxycytidine kinase2.7.1.740.455
1bk0ACVIsopenicillin N synthase1.21.3.10.454
1ia3TQ5Dihydrofolate reductase1.5.1.30.454
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.454
3arwCTIChitinase A/0.454
3el51UNGag-Pol polyprotein/0.454
3g7fUQ1Reaction center protein L chain/0.454
3pdqKC6Lysine-specific demethylase 4A1.14.110.454
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.454
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4eiyZMAAdenosine receptor A2a/0.454
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.454
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.454
1c72EPYGlutathione S-transferase 22.5.1.180.453
1e7aPFLSerum albumin/0.453
1efaNPFLactose operon repressor/0.453
1eioGCHGastrotropin/0.453
1mvsDTMDihydrofolate reductase1.5.1.30.453
1nzwNAIAldehyde dehydrogenase, mitochondrial1.2.1.30.453
1p33MTXPteridine reductase 11.5.1.330.453
1yw8A75Methionine aminopeptidase 2/0.453
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.453
2fhnBNIAvidin-related protein 4/5/0.453
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.453
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.453
3nwxKVSGag-Pol polyprotein3.4.23.160.453
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.453
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4equG6ISerine/threonine-protein kinase 102.7.11.10.453
4l17DNQGlutamate receptor 2/0.453
4qzuRTLRetinol-binding protein 2/0.453
4xulGTPUncharacterized protein mg662/0.453
5g53NECAdenosine receptor A2a/0.453
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.452
2j9gADPBiotin carboxylase6.3.4.140.452
3p74FMNPentaerythritol tetranitrate reductase/0.452
3qihNI7Gag-Pol polyprotein3.4.23.160.452
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.452
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.452
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.452
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.452
4q1w017Gag-Pol polyprotein3.4.23.160.452
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.452
5k2dZMAAdenosine receptor A2a/0.452
1hfpMOTDihydrofolate reductase1.5.1.30.451
1it7GUNtRNA-guanine(15) transglycosylase2.4.2.480.451
1qoqIGPTryptophan synthase alpha chain/0.451
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1ygkRRCPyridoxal kinase2.7.1.350.451
2ed3SAHDiphthine synthase/0.451
2h00SAHU6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase/0.451
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.451
2rkvZBATrichothecene 3-O-acetyltransferase/0.451
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
4az3S35Lysosomal protective protein3.4.16.50.451
4edy9PQHematopoietic prostaglandin D synthase/0.451
4gb20LQGag-Pol polyprotein2.7.7.490.451
4ibmIR1Insulin receptor2.7.10.10.451
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.451
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.450
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.450
2y6fM9FIsopenicillin N synthase1.21.3.10.450
3atzFMNProstaglandin F2a synthase/0.450
3ekx1UNGag-Pol polyprotein3.4.23.160.450
3njoPYVAbscisic acid receptor PYR1/0.450
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.450
3otwCOAPhosphopantetheine adenylyltransferase/0.450
4kd79DRDihydrofolate reductase1.5.1.30.450
4twnB96Ephrin type-A receptor 32.7.10.10.450
5iu86DZAdenosine receptor A2a/0.450
1eqyATPActin, alpha skeletal muscle/0.449
1h1q2A6Cyclin-dependent kinase 22.7.11.220.449
1k8y13PTryptophan synthase alpha chain/0.449
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.449
1u0wSTLChalcone synthase 22.3.1.740.449
1vbmYSATyrosine--tRNA ligase6.1.1.10.449
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.449
2uxiG50HTH-type transcriptional regulator TtgR/0.449
2ykiYKIHeat shock protein HSP 90-alpha/0.449
2zs8ADPPantothenate kinase2.7.1.330.449
3t54ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.449
3t8vBTJM1 family aminopeptidase3.4.110.449
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
4bwaN0BPyrrolysine--tRNA ligase/0.449
4eol1ROCyclin-dependent kinase 22.7.11.220.449
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.449
4kbn25UDihydrofolate reductase1.5.1.30.449
4m6l21VDihydrofolate reductase1.5.1.30.449
4tx9AMZPhosphoribosyl isomerase A/0.449
1pq944BOxysterols receptor LXR-beta/0.448
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.448
1t7o152Carnitine O-acetyltransferase2.3.1.70.448
1u3s797Estrogen receptor beta/0.448
1z7yAA5Cysteine synthase 12.5.1.470.448
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.448
2jfz003Glutamate racemase/0.448
3kb0A8SAbscisic acid receptor PYL2/0.448
3q3cNADNAD-dependent L-serine dehydrogenase/0.448
4h6pFMNChromate reductase/0.448
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.448
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.448
4uhrNGIAdenosine receptor A2a/0.448
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.447
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.447
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
1kqwRTLCellular retinol-binding protein type II/0.447
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.447
1rftPXMPyridoxal kinase2.7.1.350.447
1s19MC9Vitamin D3 receptor/0.447
1sguMK1Gag-Pol polyprotein3.4.23.160.447
1xi2CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
1yw7A41Methionine aminopeptidase 2/0.447
2cjfRP43-dehydroquinate dehydratase4.2.1.100.447
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.447
2pauD5M5'-deoxynucleotidase YfbR/0.447
3ar612DSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3gep24HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.447
3lfcZ86Mitogen-activated protein kinase 14/0.447
3negPYVAbscisic acid receptor PYL1/0.447
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.447
3qwiCUE17beta-hydroxysteroid dehydrogenase/0.447
3zs5SB2Mitogen-activated protein kinase 14/0.447
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.447
4ddrMMVDihydrofolate reductase1.5.1.30.447
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.447
5dp2NAPCurF/0.447
5epeSAHUncharacterized protein/0.447
1bxsNADRetinal dehydrogenase 11.2.1.360.446
1cdeGARPhosphoribosylglycinamide formyltransferase/0.446
1hpxKNIGag-Pol polyprotein/0.446
1kmvLIIDihydrofolate reductase1.5.1.30.446
1tl7FOKAdenylate cyclase type 2/0.446
1tl7FOKAdenylate cyclase type 5/0.446
1ybgTAVUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
1ygjRMCPyridoxal kinase2.7.1.350.446
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.446
2bpy3INGag-Pol polyprotein3.4.23.160.446
2ejzSAHDiphthine synthase/0.446
2jb4A14Isopenicillin N synthase1.21.3.10.446
2pj4414Carboxypeptidase B/0.446
2pwcG3GGag-Pol polyprotein3.4.23.160.446
2r3wG3GGag-Pol polyprotein3.4.23.160.446
2w6mOA1Biotin carboxylase6.3.4.140.446
2xtbKRMAdenosine kinase, putative/0.446
2ydvNECAdenosine receptor A2a/0.446
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3arqDM5Chitinase A/0.446
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3elm24FCollagenase 33.4.240.446
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.446
3up3XCAaceDAF-12/0.446
4jlj1NMDeoxycytidine kinase2.7.1.740.446
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4xivADPChemotaxis protein CheA2.7.13.30.446
4z24FADPutative GMC-type oxidoreductase R13510.446
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.446
1db1VDXVitamin D3 receptor/0.445
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1ftlDNQGlutamate receptor 2/0.445
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.445
1w1rZEACytokinin dehydrogenase 11.5.99.120.445
2bnsMSTReaction center protein L chain/0.445
2gr1FADFerredoxin reductase/0.445
2hamC33Vitamin D3 receptor/0.445
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
3s00Z60Cyclin-dependent kinase 22.7.11.220.445
3sacAF8Protease/0.445
4a6cQG9Gag-Pol polyprotein3.4.23.160.445
4az0S61Lysosomal protective protein3.4.16.50.445
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.445
4hy6FJ1Heat shock protein HSP 90-alpha/0.445
4v0s2HN3-dehydroquinate dehydratase4.2.1.100.445
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.445
1bzfTMQDihydrofolate reductase1.5.1.30.444
1cqxFADFlavohemoprotein/0.444
1gc5ADPADP-dependent glucokinase2.7.1.1470.444
1h51FMNPentaerythritol tetranitrate reductase/0.444
1i58ACPChemotaxis protein CheA2.7.13.30.444
1pd8CO4Dihydrofolate reductase1.5.1.30.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.444
1synF89Thymidylate synthase/0.444
1tkzH16Gag-Pol polyprotein2.7.7.490.444
1yhjR6CPyridoxal kinase2.7.1.350.444
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.444
2hc0AB2Protease/0.444
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.444
2ij7TPFMycocyclosin synthase1.14.21.90.444
2pl0STITyrosine-protein kinase Lck2.7.10.20.444
2qd8065Gag-Pol polyprotein3.4.23.160.444
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.444
2yk2YJWHeat shock protein HSP 90-alpha/0.444
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.444
3o9fK2DGag-Pol polyprotein/0.444
3q9bB3NAcetylpolyamine amidohydrolase/0.444
3sm2478Putative gag-pro-pol polyprotein/0.444
3uibSB2Putative mitogen-activated protein kinase/0.444
3vt5YI2Vitamin D3 receptor/0.444
4a4qUX9Pol protein/0.444
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.444
4dhyS41Glucokinase2.7.1.20.444
4fgh0U6Dihydrofolate reductase1.5.1.30.444
4iui1GQEstrogen receptor/0.444
4iyg1HUStrictosidine synthase4.3.3.20.444
4l5b1UXDeoxycytidine kinase2.7.1.740.444
4mv4ACPBiotin carboxylase6.3.4.140.444
4n3r2GUTankyrase-12.4.2.300.444
5iw4NADNADH pyrophosphatase/0.444
1fw0KAIGlutamate receptor 2/0.443
1hbvGANGag-Pol polyprotein/0.443
1kmsLIHDihydrofolate reductase1.5.1.30.443
1mc1PCXCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.443
1s4mLUMRiboflavin biosynthesis protein/0.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2bt4CA23-dehydroquinate dehydratase4.2.1.100.443
2cftPLPPyridoxal phosphate phosphatase/0.443
2w3mFOLDihydrofolate reductase1.5.1.30.443
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.443
2zevB71Geranylgeranyl pyrophosphate synthase/0.443
3cgeNDPCoenzyme A disulfide reductase/0.443
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3ns2PYVAbscisic acid receptor PYL2/0.443
3nxrD2DDihydrofolate reductase1.5.1.30.443
3sa8K83Protease/0.443
4e2bFMNDehydrogenase/0.443
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
4iae1DXAlr2278 protein/0.443
4j55031Gag-Pol polyprotein3.4.23.160.443
4jq4IMNAldo-keto reductase family 1 member C2/0.443
4jrnANPRhoptry kinase family protein/0.443
4l0oPLPCystathionine gamma-synthase2.5.1.480.443
4ug5H4BNitric oxide synthase oxygenase1.14.13.1650.443
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.443
4xivACPChemotaxis protein CheA2.7.13.30.443
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
5iua6DXAdenosine receptor A2a/0.443
3sn6P0GBeta-2 adrenergic receptor/0.443
1brpRTLRetinol-binding protein 4/0.442
1h50FMNPentaerythritol tetranitrate reductase/0.442
1kvkATPMevalonate kinase2.7.1.360.442
1kzjCB3Thymidylate synthase/0.442
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
1nzq162Prothrombin3.4.21.50.442
1wn3HXCPhenylacetic acid degradation protein PaaI/0.442
2a94AP0L-lactate dehydrogenase1.1.1.270.442
2b1z17MEstrogen receptor/0.442
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.442
2csnCKICasein kinase I homolog 12.7.11.10.442
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.442
2in6839Wee1-like protein kinase2.7.10.20.442
2q641UNGag-Pol polyprotein3.4.23.160.442
2x8hFADThioredoxin glutathione reductase/0.442
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2zbaZBATrichothecene 3-O-acetyltransferase/0.442
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
3f03FMNPentaerythritol tetranitrate reductase/0.442
3fhxPLPPyridoxal kinase2.7.1.350.442
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.442
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3p9tTCLRepressor/0.442
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.442
3rl45GPMetallophosphoesterase MPPED23.10.442
3sa4F72Protease/0.442
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4bfvZVVPantothenate kinase2.7.1.330.442
4bfwZVWPantothenate kinase2.7.1.330.442
4em9TCEPeroxisome proliferator-activated receptor gamma/0.442
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.442
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.442
4ixd1HVIntegrin alpha-L/0.442
4kne1CYDihydrofolate reductase1.5.1.30.442
4p9dTMPDeoxycytidylate deaminase/0.442
5auuLU2Death-associated protein kinase 12.7.11.10.442
5iqiGNPBifunctional AAC/APH2.3.10.442
5iu4ZMAAdenosine receptor A2a/0.442
5kp2COA3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2/0.442
3reyXACAdenosine receptor A2a/0.442
1bv9XV6Gag-Pol polyprotein3.4.23.160.441
1fmjRTLRetinol dehydratase/0.441
1j1zATPArgininosuccinate synthase/0.441
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.441
1nbiSAMGlycine N-methyltransferase2.1.1.200.441
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.441
2hqpNDPDihydrofolate reductase1.5.1.30.441
2jedLG8Protein kinase C theta type2.7.11.130.441
2pdtFADVivid PAS protein VVD/0.441
2puiADPMethylthioribose kinase2.7.1.1000.441
2r43G3GGag-Pol polyprotein3.4.23.160.441
2rf2MRXGag-Pol polyprotein2.7.7.490.441
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.441
2x9dITCTetracycline repressor protein class D/0.441
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.441
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3ekuCY9Actin-5C/0.441
3frdDHFDihydrofolate reductase1.5.1.30.441
3hv3R49Mitogen-activated protein kinase 14/0.441
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3jpuTY4Transcriptional activator protein LasR/0.441
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.441
3n0yAPCAdenylate cyclase 2/0.441
3pe2E1BCasein kinase II subunit alpha2.7.11.10.441
3ucb017Gag-Pol polyprotein/0.441
3wquATPCell division protein FtsA/0.441
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.441
4dbs0HVAldo-keto reductase family 1 member C3/0.441
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
4eftEFTHeat shock protein HSP 90-alpha/0.441
4fnyI3KALK tyrosine kinase receptor2.7.10.10.441
4g1y0VOVitamin D3 receptor A/0.441
4gk2L66Ephrin type-A receptor 32.7.10.10.441
4jhz1KVBeta-glucuronidase3.2.1.310.441
4l8u9AZSerum albumin/0.441
4lt63ATPoly(A) polymerase gamma2.7.7.190.441
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
5d9j0N8Polymerase acidic protein/0.441
1cjkFOKAdenylate cyclase type 2/0.440
1cjkFOKAdenylate cyclase type 5/0.440
1g28FMNPHY3/0.440
1jpaANPEphrin type-B receptor 22.7.10.10.440
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.440
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.440
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2bakAQZMitogen-activated protein kinase 14/0.440
2fk8SAMHydroxymycolate synthase MmaA42.1.10.440
2nsd4PIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.440
2xvw9NRSerum albumin/0.440
2yac937Serine/threonine-protein kinase PLK12.7.11.210.440
2z4sADPChromosomal replication initiator protein DnaA/0.440
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.440
3ewrAPRReplicase polyprotein 1a3.4.220.440
3koo24DBifunctional epoxide hydrolase 23.3.2.100.440
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.440
3nr4PYVAbscisic acid receptor PYL2/0.440
3nxyD2HDihydrofolate reductase1.5.1.30.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
3p8jFMNPentaerythritol tetranitrate reductase/0.440
3tubFPUTyrosine-protein kinase SYK2.7.10.20.440
3zkuHCVIsopenicillin N synthase1.21.3.10.440
4a2aATPCell division protein FtsA/0.440
4a9yAQZMitogen-activated protein kinase 14/0.440
4e4n0NLTyrosine-protein kinase JAK1/0.440
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.440
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.440
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.440
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.440
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.440