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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2gtbAZPOrf1ab polyprotein

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2gtbAZPOrf1ab polyprotein/1.000
2a5kAZPReplicase polyprotein 1ab3.4.220.642
2gz8F3FOrf1a polyprotein/0.524
2qiqCYVReplicase polyprotein 1ab/0.519
3qgf46FGenome polyprotein2.7.7.480.514
4ke11R6Beta-secretase 13.4.23.460.514
1xe55FEPlasmepsin-23.4.23.390.512
4frkDWDBeta-secretase 13.4.23.460.511
1nvtNAPShikimate dehydrogenase (NADP(+))/0.510
3qt62P0Mevalonate diphosphate decarboxylase/0.505
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.503
2cy0NAPShikimate dehydrogenase (NADP(+))/0.502
1o9bNAIQuinate/shikimate dehydrogenase/0.501
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.496
1vi2NADQuinate/shikimate dehydrogenase/0.491
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.489
1g63FMNEpidermin decarboxylase4.1.10.488
2owgSAHDiphthine synthase/0.488
3vydVYDRenin3.4.23.150.488
4bfzZVZPantothenate kinase2.7.1.330.488
2ejkSAHDiphthine synthase/0.487
2hk9NAPShikimate dehydrogenase (NADP(+))/0.487
4fxy0W2Neurolysin, mitochondrial3.4.24.160.486
1w6hTITPlasmepsin-23.4.23.390.485
2a94AP0L-lactate dehydrogenase1.1.1.270.485
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.485
4nbwNADShort-chain dehydrogenase/reductase SDR/0.485
1rx8NAPDihydrofolate reductase1.5.1.30.484
1a5bIGPTryptophan synthase alpha chain/0.483
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.483
3ixp834Ecdysone receptor/0.483
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.482
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.481
2g1y5IGRenin3.4.23.150.481
2op9WR1Orf1ab polyprotein/0.480
3phiNDPShikimate dehydrogenase (NADP(+))/0.480
1kp2ATPArgininosuccinate synthase6.3.4.50.479
1t2cNAIL-lactate dehydrogenase1.1.1.270.477
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.477
1xe65FPPlasmepsin-23.4.23.390.476
2pncCLUPrimary amine oxidase, liver isozyme/0.476
2ejzSAHDiphthine synthase/0.475
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.475
4q71FADBifunctional protein PutA/0.475
2a9y26AAdenosine kinase2.7.1.200.474
2dsgSAHDiphthine synthase/0.474
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.474
4acxS8ZBeta-secretase 13.4.23.460.474
3oafOAGDihydrofolate reductase1.5.1.30.473
2ev9NAPShikimate dehydrogenase (NADP(+))/0.472
2g8yNADHydroxycarboxylate dehydrogenase B/0.472
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.472
3phjDHKShikimate dehydrogenase (NADP(+))/0.472
3t4eNADQuinate/shikimate dehydrogenase/0.472
1kkq471Peroxisome proliferator-activated receptor alpha/0.471
1psa0ZLPepsin A3.4.23.10.471
2c20NADUDP-glucose 4-epimerase/0.471
2g20L1ARenin3.4.23.150.471
3s3vTOPDihydrofolate reductase1.5.1.30.471
1lbcCYZGlutamate receptor 2/0.470
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.470
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.470
5dp2NAPCurF/0.470
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.469
2e8qSAHDiphthine synthase/0.469
2p6lSAHDiphthine synthase/0.469
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.469
4ejmNAPPutative zinc-binding dehydrogenase/0.469
1g1aNADdTDP-glucose 4,6-dehydratase/0.468
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.468
4h1e10JBeta-secretase 13.4.23.460.468
2ek7SAHDiphthine synthase/0.467
2g1s4IGRenin3.4.23.150.467
2rlcCHDCholoylglycine hydrolase3.5.1.240.467
3vqsJT1Genome polyprotein/0.467
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1mjbACOHistone acetyltransferase ESA1/0.466
1rneC60Renin3.4.23.150.466
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.466
3h3t16HCollagen type IV alpha-3-binding protein/0.466
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.466
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.466
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.465
3h3r14HCollagen type IV alpha-3-binding protein/0.465
4a86H35Major pollen allergen Bet v 1-A/0.465
4boeCLRJapanin/0.465
1nytNAPShikimate dehydrogenase (NADP(+))/0.464
2znq401Peroxisome proliferator-activated receptor delta/0.464
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.464
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.464
3sp9IL2Peroxisome proliferator-activated receptor delta/0.464
4b7754MBeta-secretase 13.4.23.460.464
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.463
2eldSAHDiphthine synthase/0.463
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.463
2he5NDPAldo-keto reductase family 1 member C211.1.10.463
2ovhAS0Progesterone receptor/0.463
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.463
3fwgCAMCamphor 5-monooxygenase1.14.15.10.463
4a8v2ANMajor pollen allergen Bet v 1-J/0.463
4ke01R8Beta-secretase 13.4.23.460.463
1beuIPLTryptophan synthase alpha chain/0.462
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.462
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.462
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.462
2pb4SAHDiphthine synthase/0.462
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.462
2ym2FADPhenylacetone monooxygenase1.14.13.920.462
3fhyATPPyridoxal kinase2.7.1.350.462
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.462
4acuQN7Beta-secretase 13.4.23.460.462
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.462
1bil0IURenin3.4.23.150.461
1tqf32PBeta-secretase 13.4.23.460.461
1w0kADPATP synthase subunit alpha, mitochondrial/0.461
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.461
2gjlFMNNitronate monooxygenase1.13.12.160.461
2gjnFMNNitronate monooxygenase1.13.12.160.461
2zcvNDPQuinone oxidoreductase 21.6.5.20.461
3gviADPMalate dehydrogenase/0.461
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.461
4a83DXCMajor pollen allergen Bet v 1-A/0.461
4c4oNADSADH/0.461
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.461
5fwnNAPPutative dehydrogenase/0.461
1gw2FERPeroxidase C1A1.11.1.70.460
1xvaSAMGlycine N-methyltransferase2.1.1.200.460
2e7rSAHDiphthine synthase/0.460
2eniSAHDiphthine synthase/0.460
3u9eCOALmo1369 protein/0.460
3wqmB29Diterpene synthase3.1.7.80.460
4a862ANMajor pollen allergen Bet v 1-A/0.460
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.460
5k5zANPUncharacterized protein/0.460
1me6IVSPlasmepsin-23.4.23.390.459
1p0pBCHCholinesterase3.1.1.80.459
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.459
1xelUPGUDP-glucose 4-epimerase5.1.3.20.459
3ik6HCZGlutamate receptor 2/0.459
3lqfNADGalactitol dehydrogenase/0.459
3wrlCAMCamphor 5-monooxygenase1.14.15.10.459
4azy7F3Beta-secretase 13.4.23.460.459
4bfxZVXPantothenate kinase2.7.1.330.459
4dc0NDPPutative ketoacyl reductase1.3.10.459
4friDWABeta-secretase 13.4.23.460.459
4g7gVFVLanosterol 14-alpha-demethylase/0.459
4ycpFMNtRNA-dihydrouridine(16) synthase/0.459
5a9sNAPPutative dehydrogenase/0.459
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.458
1ra8FOLDihydrofolate reductase1.5.1.30.458
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.458
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.458
2il2LIXRenin3.4.23.150.458
2rqfJH3Hemolymph juvenile hormone binding protein/0.458
3h3qH13Collagen type IV alpha-3-binding protein/0.458
3vyfVYFRenin3.4.23.150.458
4dh60KNBeta-secretase 13.4.23.460.458
4dptAGSMevalonate diphosphate decarboxylase/0.458
4h3f10OBeta-secretase 13.4.23.460.458
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.458
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.458
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1jipKTN6-deoxyerythronolide B hydroxylase/0.457
1o76CAMCamphor 5-monooxygenase1.14.15.10.457
2anb5GPGuanylate kinase2.7.4.80.457
2dftADPShikimate kinase2.7.1.710.457
2dv4SAHDiphthine synthase/0.457
2g1n1IGRenin3.4.23.150.457
2owkSAHDiphthine synthase/0.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3p62FMNPentaerythritol tetranitrate reductase/0.457
3tjzGNPADP-ribosylation factor 1/0.457
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.457
4m83ERYOleandomycin glycosyltransferase2.4.10.457
4p9dTMPDeoxycytidylate deaminase/0.457
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
1npdNADQuinate/shikimate dehydrogenase/0.456
2vwqNAPGlucose 1-dehydrogenase/0.456
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.456
3i0pNADMalate dehydrogenase, putative/0.456
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.456
3own3OWRenin3.4.23.150.456
3rbaCODPhosphopantetheine adenylyltransferase/0.456
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.456
4djaFAD(6-4) photolyase/0.456
4djw0KPBeta-secretase 13.4.23.460.456
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.456
4pleCPSNuclear receptor subfamily 5 group A member 2/0.456
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.456
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.456
1rz0FADPhenol 2-hydroxylase component B/0.455
2d8aNADL-threonine 3-dehydrogenase/0.455
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.455
3d4pNADL-lactate dehydrogenase 11.1.1.270.455
3p84FMNPentaerythritol tetranitrate reductase/0.455
3pqbVGPPutative oxidoreductase/0.455
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.455
4a802ANMajor pollen allergen Bet v 1-A/0.455
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.455
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.455
4h3j10WBeta-secretase 13.4.23.460.455
1a72PADAlcohol dehydrogenase E chain1.1.1.10.454
1ddsMTXDihydrofolate reductase1.5.1.30.454
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.454
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.454
2g1r3IGRenin3.4.23.150.454
2hfuMEVMevalonate kinase/0.454
3t3c017Gag-Pol polyprotein3.4.23.160.454
3ziuLSSLeucyl-tRNA synthetase/0.454
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
4gm4TZDBenzoylformate decarboxylase4.1.1.70.454
1icsFMN12-oxophytodienoate reductase 11.3.1.420.453
1rfuADPPyridoxal kinase2.7.1.350.453
1tehNADAlcohol dehydrogenase class-31.1.1.10.453
1udbUFGUDP-glucose 4-epimerase5.1.3.20.453
1wngSAHDiphthine synthase/0.453
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.453
2v16C47Renin3.4.23.150.453
2xuoTZ4Acetylcholinesterase3.1.1.70.453
3h3sH15Collagen type IV alpha-3-binding protein/0.453
3r9uFADThioredoxin reductase/0.453
3s79ASDAromatase1.14.14.140.453
4dbzNDPPutative ketoacyl reductase1.3.10.453
4dfg0JVGag-Pol polyprotein3.4.23.160.453
4loi1YCStimulator of interferon genes protein/0.453
1fmjRTLRetinol dehydratase/0.452
1vhzAPRADP compounds hydrolase NudE3.6.10.452
2ab8MTPAdenosine kinase2.7.1.200.452
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2dxxSAHDiphthine synthase/0.452
2el3SAHDiphthine synthase/0.452
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3cobADPKinesin heavy chain-like protein/0.452
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.452
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.452
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.452
3wrjCAMCamphor 5-monooxygenase1.14.15.10.452
4emtC2EStimulator of interferon genes protein/0.452
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.452
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.452
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.452
1pjcNADAlanine dehydrogenase/0.451
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.451
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.451
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.451
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.451
2fznFADBifunctional protein PutA1.5.5.20.451
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.451
2p5cSAHDiphthine synthase/0.451
2qbuSAHPrecorrin-2 methyltransferase/0.451
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.451
2x8gFADThioredoxin glutathione reductase/0.451
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3f03FMNPentaerythritol tetranitrate reductase/0.451
3ggj25HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.451
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.451
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4d89BXDBeta-secretase 13.4.23.460.451
4du82P0Mevalonate diphosphate decarboxylase/0.451
4g95OAGDihydrofolate reductase1.5.1.30.451
4lol1YEStimulator of interferon genes protein/0.451
4rvdSAMD-mycarose 3-C-methyltransferase/0.451
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.451
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.450
1y9dTPPPyruvate oxidase1.2.3.30.450
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.450
2dv3SAHDiphthine synthase/0.450
2e0nSAHPrecorrin-2 C20-methyltransferase/0.450
2g1o2IGRenin3.4.23.150.450
2hr8SAHDiphthine synthase/0.450
2owuSAHDiphthine synthase/0.450
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.450
2znpK55Peroxisome proliferator-activated receptor delta/0.450
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3qwbNDPProbable quinone oxidoreductase1.6.5.50.450
3vucHHERenin3.4.23.150.450
3wv9FEGHmd co-occurring protein HcgE/0.450
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.450
4la1FADThioredoxin glutathione reductase/0.450
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.450
1bwsNDPGDP-L-fucose synthase/0.449
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.449
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.449
3csoXNIGenome polyprotein2.7.7.480.449
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.449
3n0hTOPDihydrofolate reductase1.5.1.30.449
3own3OXRenin3.4.23.150.449
4a6bQG8Gag-Pol polyprotein3.4.23.160.449
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.449
4g47TZFMycocyclosin synthase1.14.21.90.449
5cyoGDPSeptin-9/0.449
1eioGCHGastrotropin/0.448
1h51FMNPentaerythritol tetranitrate reductase/0.448
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.448
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.448
1re7FOLDihydrofolate reductase1.5.1.30.448
1udaUFGUDP-glucose 4-epimerase5.1.3.20.448
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.448
2dsiSAHDiphthine synthase/0.448
2dxvSAHDiphthine synthase/0.448
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2hizLIJBeta-secretase 13.4.23.460.448
2i4qUA4Renin3.4.23.150.448
2q5g1FAPeroxisome proliferator-activated receptor delta/0.448
3fhxPLPPyridoxal kinase2.7.1.350.448
3ixj586Beta-secretase 13.4.23.460.448
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3nsh957Beta-secretase 13.4.23.460.448
3slkNDPPolyketide synthase extender module 2/0.448
3zoiM2WIsopenicillin N synthase1.21.3.10.448
4b4vL34Bifunctional protein FolD/0.448
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
4i0i957Beta-secretase 13.4.23.460.448
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
5d3qGDPDynamin-13.6.5.50.448
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.448
1bk0ACVIsopenicillin N synthase1.21.3.10.447
1ipeNDPTropinone reductase 21.1.1.2360.447
1khrVIRStreptogramin A acetyltransferase2.3.10.447
1mvtDTMDihydrofolate reductase1.5.1.30.447
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1x2hLPALipoate-protein ligase A6.3.1.200.447
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.447
2fk8SAMHydroxymycolate synthase MmaA42.1.10.447
2i7pACOPantothenate kinase 32.7.1.330.447
2p4j23IBeta-secretase 13.4.23.460.447
2p83MR0Beta-secretase 13.4.23.460.447
2qbmCAMCamphor 5-monooxygenase1.14.15.10.447
2wd8VGFPteridine reductase/0.447
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.447
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.447
2zbaZBATrichothecene 3-O-acetyltransferase/0.447
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.447
3af1GDPPantothenate kinase2.7.1.330.447
3kb1ADPIron-sulfur cluster carrier protein/0.447
4b0qGMFBeta-secretase 13.4.23.460.447
1hfqMOTDihydrofolate reductase1.5.1.30.446
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.446
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.446
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.446
1msmJE2Gag-Pol polyprotein3.4.23.160.446
1ra3MTXDihydrofolate reductase1.5.1.30.446
1w34FADFerredoxin--NADP reductase1.18.1.20.446
1yb5NAPQuinone oxidoreductase1.6.5.50.446
2dfvNADL-threonine 3-dehydrogenase/0.446
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.446
2p6iSAHDiphthine synthase/0.446
2xlpFADPutative flavin-containing monooxygenase/0.446
2xukTZ5Acetylcholinesterase3.1.1.70.446
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.446
3gbuATPUncharacterized sugar kinase PH14592.7.10.446
3k5c0BIBeta-secretase 13.4.23.460.446
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4awp99AHeat shock protein HSP 90-alpha/0.446
4bftZVTPantothenate kinase2.7.1.330.446
4bfvZVVPantothenate kinase2.7.1.330.446
4bgg844Activin receptor type-12.7.11.300.446
4fizCUE17beta-hydroxysteroid dehydrogenase/0.446
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.446
4v2gITCTetracycline repressor protein class D/0.446
1cf3FADGlucose oxidase1.1.3.40.445
1f20FADNitric oxide synthase, brain1.14.13.390.445
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.445
1mj9COAHistone acetyltransferase ESA1/0.445
1qoqIGPTryptophan synthase alpha chain/0.445
1vbiNADMalate/L-lactate dehydrogenase family protein/0.445
1xddAAYIntegrin alpha-L/0.445
2bjfDXCCholoylglycine hydrolase3.5.1.240.445
2c27ACOMycothiol acetyltransferase2.3.1.1890.445
2fj1CTCTetracycline repressor protein class D/0.445
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.445
2ohvNHLGlutamate racemase/0.445
2p5uNADUDP-glucose 4-epimerase/0.445
3s1dZIRCytokinin dehydrogenase 11.5.99.120.445
3wrhCAMCamphor 5-monooxygenase1.14.15.10.445
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.445
4lhvGDPRas-related protein Rab-8A/0.445
4m6jNDPDihydrofolate reductase1.5.1.30.445
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4wecNADShort chain dehydrogenase/0.445
5kwvANPPantothenate synthetase/0.445
1hb1OCVIsopenicillin N synthase1.21.3.10.444
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.444
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.444
1x1bSAHC-20 methyltransferase/0.444
2egbSAHDiphthine synthase/0.444
2ejjSAHDiphthine synthase/0.444
2oz57XYUncharacterized protein/0.444
2vijC44Beta-secretase 13.4.23.460.444
2xfsJ01Uncharacterized protein/0.444
2z6rSAHDiphthine synthase/0.444
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.444
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.444
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.444
3t3r9PLCytochrome P450 2A61.14.130.444
3vswR31Renin3.4.23.150.444
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.444
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.444
4f31KAIGlutamate receptor 3/0.444
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.444
4k28NADShikimate dehydrogenase family protein/0.444
4ktkKTKCytochrome P450/0.444
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.444
4o63NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.444
4oqyNDP(S)-imine reductase/0.444
4wxxSAHDNA (cytosine-5)-methyltransferase 12.1.1.370.444
5itzGTPTubulin alpha-1B chain/0.444
1fm4DXCMajor pollen allergen Bet v 1-L/0.443
1pd9CO4Dihydrofolate reductase1.5.1.30.443
2g226IGRenin3.4.23.150.443
3b70NAPEnoyl reductase LovC10.443
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3jv7NADSecondary alcohol dehydrogenase/0.443
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.443
3v3m0ENReplicase polyprotein 1a3.4.19.120.443
3vv8B02Beta-secretase 13.4.23.460.443
4d03FADPhenylacetone monooxygenase1.14.13.920.443
4exg916Beta-secretase 13.4.23.460.443
4gddNAIUDP-galactopyranose mutase/0.443
4kgkGTPUncharacterized protein/0.443
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.443
4yekTHMThymidine phosphorylase/0.443
1drhNAPDihydrofolate reductase1.5.1.30.442
1qrpHH0Pepsin A-43.4.23.10.442
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.442
1yrdCAMCamphor 5-monooxygenase1.14.15.10.442
2abaSTRPentaerythritol tetranitrate reductase/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2feuCAMCamphor 5-monooxygenase1.14.15.10.442
2huxSAHDiphthine synthase/0.442
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.442
2p9dSAHDiphthine synthase/0.442
2po7CHDFerrochelatase, mitochondrial4.99.1.10.442
2uxhQUEHTH-type transcriptional regulator TtgR/0.442
2ylxFADPhenylacetone monooxygenase1.14.13.920.442
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3gqvNAPEnoyl reductase LovC10.442
3ixk929Beta-secretase 13.4.23.460.442
3lqsPSZD-alanine aminotransferase2.6.1.210.442
3rsv3RSBeta-secretase 13.4.23.460.442
3tnlNADShikimate dehydrogenase (NADP(+))/0.442
3to6LYS_CMCHistone acetyltransferase ESA1/0.442
3vsxR32Renin3.4.23.150.442
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.442
4a87NARMajor pollen allergen Bet v 1-A/0.442
4b4w9L9Bifunctional protein FolD/0.442
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.442
4h4rFADBiphenyl dioxygenase ferredoxin reductase subunit/0.442
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.442
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.442
1dhfFOLDihydrofolate reductase1.5.1.30.441
1draMTXDihydrofolate reductase1.5.1.30.441
1e79ATPATP synthase subunit alpha, mitochondrial/0.441
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.441
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.441
1i6kTYMTryptophan--tRNA ligase6.1.1.20.441
1icpFMN12-oxophytodienoate reductase 11.3.1.420.441
1kfbIGPTryptophan synthase alpha chain/0.441
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1tllFMNNitric oxide synthase, brain1.14.13.390.441
1u4dDBQActivated CDC42 kinase 1/0.441
1u71MXADihydrofolate reductase1.5.1.30.441
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.441
2ignFADPyranose 2-oxidase/0.441
2ovmAS0Progesterone receptor/0.441
2owfSAHDiphthine synthase/0.441
2p6dSAHDiphthine synthase/0.441
2pb5SAHDiphthine synthase/0.441
2yj4ATPCopper-transporting ATPase/0.441
3cic316Beta-secretase 13.4.23.460.441
3fazNOSPurine nucleoside phosphorylase/0.441
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.441
3orfNADDihydropteridine reductase1.5.1.340.441
3p67FMNPentaerythritol tetranitrate reductase/0.441
4j0v1H7Beta-secretase 13.4.23.460.441
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.441
4m4922YL-lactate dehydrogenase A chain1.1.1.270.441
4q72FADBifunctional protein PutA/0.441
1dyjDDFDihydrofolate reductase1.5.1.30.440
1f0yCAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1fw0KAIGlutamate receptor 2/0.440
1i5eU5PUracil phosphoribosyltransferase/0.440
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2b7aIZATyrosine-protein kinase JAK2/0.440
2eeqSAHDiphthine synthase/0.440
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2wedPP6Penicillopepsin-13.4.23.200.440
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
2zvbSAHPrecorrin-3 C17-methyltransferase/0.440
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3ful52DLeukotriene A-4 hydrolase3.3.2.60.440
3fwjCAMCamphor 5-monooxygenase1.14.15.10.440
3q43D66M1 family aminopeptidase3.4.110.440
3qge26FGenome polyprotein2.7.7.480.440
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.440
3tqaNDPDihydrofolate reductase/0.440
3w3zGTPGTP-binding nuclear protein Ran/0.440
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.440
4fweFADLysine-specific histone demethylase 1B10.440
4gg1TZDBenzoylformate decarboxylase4.1.1.70.440
4k8s1QTBeta-secretase 13.4.23.460.440