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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2gksADPProbable bifunctional SAT/APS kinase2.7.1.25

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2gksADPProbable bifunctional SAT/APS kinase2.7.1.251.000
1towCRZFatty acid-binding protein, adipocyte/0.502
4du82P0Mevalonate diphosphate decarboxylase/0.500
1nzdUPGDNA beta-glucosyltransferase/0.493
3fr5I4AFatty acid-binding protein, adipocyte/0.493
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.490
2vhtATPNTPase P4/0.489
3h86AP5Adenylate kinase/0.484
2bxmIMNSerum albumin/0.483
1mjaCOAHistone acetyltransferase ESA1/0.481
2oapANPType II secretion system protein (GspE-2)/0.481
2vttLZDCyclin-dependent kinase 22.7.11.220.481
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.480
4m83ERYOleandomycin glycosyltransferase2.4.10.480
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.478
2nnqT4BFatty acid-binding protein, adipocyte/0.478
4m6jNDPDihydrofolate reductase1.5.1.30.478
3hk1B64Fatty acid-binding protein, adipocyte/0.477
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.477
2qenADPWalker-Type ATPase/0.476
2dv3SAHDiphthine synthase/0.475
3nmpPYVAbscisic acid receptor PYL2/0.475
3p62FMNPentaerythritol tetranitrate reductase/0.474
4i1iNADMalate dehydrogenase/0.474
4k28NADShikimate dehydrogenase family protein/0.474
1pjcNADAlanine dehydrogenase/0.473
2qo9ANPEphrin type-A receptor 32.7.10.10.473
4dfg0JVGag-Pol polyprotein3.4.23.160.473
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.472
1o9bNAIQuinate/shikimate dehydrogenase/0.472
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.472
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
3p8jFMNPentaerythritol tetranitrate reductase/0.472
4ehuANP2-hydroxyisocaproyl-CoA dehydratase activator/0.472
1nvtNAPShikimate dehydrogenase (NADP(+))/0.471
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.471
1g1aNADdTDP-glucose 4,6-dehydratase/0.470
1mjbACOHistone acetyltransferase ESA1/0.470
2fypRDEEndoplasmin/0.470
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1udcUFMUDP-glucose 4-epimerase5.1.3.20.469
2a94AP0L-lactate dehydrogenase1.1.1.270.469
2dxxSAHDiphthine synthase/0.469
2ft9CHDFatty acid-binding protein 2, liver/0.469
2qbmCAMCamphor 5-monooxygenase1.14.15.10.469
2dwbANPAurora kinase A2.7.11.10.468
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.467
1bim0QBRenin3.4.23.150.467
1drhNAPDihydrofolate reductase1.5.1.30.467
2rlcCHDCholoylglycine hydrolase3.5.1.240.467
3otwCOAPhosphopantetheine adenylyltransferase/0.467
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.466
1o76CAMCamphor 5-monooxygenase1.14.15.10.466
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
2qa2FADPolyketide oxygenase CabE/0.466
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.466
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.466
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.466
4qnwFMNChanoclavine-I aldehyde reductase easA/0.466
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.466
2b53D23Cyclin-dependent kinase 22.7.11.220.465
2hk9NAPShikimate dehydrogenase (NADP(+))/0.465
2qw034Z4-chlorobenzoyl CoA ligase/0.465
4fxy0W2Neurolysin, mitochondrial3.4.24.160.465
4h4yNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.465
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.464
1rx8NAPDihydrofolate reductase1.5.1.30.464
2huvSAHDiphthine synthase/0.464
2nniMTKCytochrome P450 2C8/0.464
2yxuATPPyridoxal kinase2.7.1.350.464
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.464
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.463
2ejjSAHDiphthine synthase/0.463
2gmvPEPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.463
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.463
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.463
3ppr4CSGlycine betaine/carnitine/choline-binding protein OpuCC/0.463
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.463
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.462
1dz8CAMCamphor 5-monooxygenase1.14.15.10.462
1m8gNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.462
1ri4SAMmRNA cap guanine-N7 methyltransferase2.1.1.560.462
1xelUPGUDP-glucose 4-epimerase5.1.3.20.462
2a9y26AAdenosine kinase2.7.1.200.462
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.462
4bfzZVZPantothenate kinase2.7.1.330.462
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.462
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.462
1dhjMTXDihydrofolate reductase1.5.1.30.461
1h50FMNPentaerythritol tetranitrate reductase/0.461
1mbtFADUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.461
1xddAAYIntegrin alpha-L/0.461
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.461
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.461
4jqlVJ6Heat shock protein HSP 90-alpha/0.461
1k8y13PTryptophan synthase alpha chain/0.460
1msnJE2Gag-Pol polyprotein3.4.23.160.460
1n77ATPGlutamate--tRNA ligase6.1.1.170.460
1ra8FOLDihydrofolate reductase1.5.1.30.460
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.460
2briANPUridylate kinase2.7.4.220.460
2e07SAHDiphthine synthase/0.460
2i5bADPPyridoxine kinase/0.460
2j4dMHFCryptochrome DASH, chloroplastic/mitochondrial/0.460
3drcMTXDihydrofolate reductase1.5.1.30.460
3p82FMNPentaerythritol tetranitrate reductase/0.460
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.460
4kne1CYDihydrofolate reductase1.5.1.30.460
4rosAPRMalate dehydrogenase/0.460
4tmbFMNOld yellow enzyme/0.460
4yp12BAStimulator of interferon genes protein/0.460
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.459
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.459
1udaUFGUDP-glucose 4-epimerase5.1.3.20.459
3u9eCOALmo1369 protein/0.459
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.459
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.459
1u71MXADihydrofolate reductase1.5.1.30.458
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2gjlFMNNitronate monooxygenase1.13.12.160.458
2xpuTDCTetracycline repressor protein class D/0.458
3asjXYMHomoisocitrate dehydrogenase/0.458
3bbrBHYGlutamate receptor 2/0.458
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.458
3d4pNADL-lactate dehydrogenase 11.1.1.270.458
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.458
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.458
3kjm245Cytokinin dehydrogenase 11.5.99.120.458
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.457
1g67TZPThiamine-phosphate synthase/0.457
1h51FMNPentaerythritol tetranitrate reductase/0.457
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.457
1v0pPVBCell division control protein 2 homolog2.7.11.220.457
2owkSAHDiphthine synthase/0.457
2x0rNADMalate dehydrogenase/0.457
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.457
3i0pNADMalate dehydrogenase, putative/0.457
3w1xXRODihydroorotate dehydrogenase (fumarate)1.3.98.10.457
4d04NAPPhenylacetone monooxygenase1.14.13.920.457
4ef4C2EStimulator of interferon genes protein/0.457
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.457
4l4eCAMCamphor 5-monooxygenase1.14.15.10.457
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.457
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.456
1i58ACPChemotaxis protein CheA2.7.13.30.456
1kp2ATPArgininosuccinate synthase6.3.4.50.456
2iyfERYOleandomycin glycosyltransferase2.4.10.456
2p3qSAHGenome polyprotein/0.456
2w06FRVCyclin-dependent kinase 22.7.11.220.456
2zbaZBATrichothecene 3-O-acetyltransferase/0.456
3af1GDPPantothenate kinase2.7.1.330.456
3apwDP0Alpha-1-acid glycoprotein 2/0.456
3bv3P39Mitogen-activated protein kinase 14/0.456
3junAKDPhenazine biosynthesis protein A/B/0.456
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.456
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.456
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.456
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.456
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
1esvLARActin, alpha skeletal muscle/0.455
1h6vNDPThioredoxin reductase 1, cytoplasmic1.8.1.90.455
1me6IVSPlasmepsin-23.4.23.390.455
1wg8SAMRibosomal RNA small subunit methyltransferase H/0.455
1xvaSAMGlycine N-methyltransferase2.1.1.200.455
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.455
2vnjFADNADPH:ferredoxin reductase/0.455
2w6qOA5Biotin carboxylase6.3.4.140.455
3mgdACOPredicted acetyltransferase/0.455
3ojlNADCap5O/0.455
3tjzGNPADP-ribosylation factor 1/0.455
4dae6CRPurine nucleoside phosphorylase DeoD-type2.4.2.10.455
4k6fNAPPutative Acetoacetyl-CoA reductase/0.455
4l4fCAMCamphor 5-monooxygenase1.14.15.10.455
1lb9DNQGlutamate receptor 2/0.454
1ytmATPPhosphoenolpyruvate carboxykinase (ATP)/0.454
2f6rACOBifunctional coenzyme A synthase/0.454
2itwITQEpidermal growth factor receptor2.7.10.10.454
2xhd7T9Glutamate receptor 2/0.454
3elcF012-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.454
3gviADPMalate dehydrogenase/0.454
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.454
3nbvANPKetohexokinase/0.454
3oetNADErythronate-4-phosphate dehydrogenase/0.454
4a4zANPAntiviral helicase SKI23.6.4.130.454
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4f5yC2EStimulator of interferon genes protein/0.454
4mvcCDCCholine-phosphate cytidylyltransferase A/0.454
4xdmGDMHeat shock cognate 90 kDa protein/0.454
1bwsNDPGDP-L-fucose synthase/0.453
1i59ADPChemotaxis protein CheA2.7.13.30.453
1j4jACOAcetyltransferase2.3.10.453
1nzfUPGDNA beta-glucosyltransferase/0.453
1sqkLARActin, alpha skeletal muscle/0.453
1tl7ONMAdenylate cyclase type 2/0.453
1tl7ONMAdenylate cyclase type 5/0.453
1w6hTITPlasmepsin-23.4.23.390.453
2a1nCAMCamphor 5-monooxygenase1.14.15.10.453
2e4nSAHDiphthine synthase/0.453
2zshGA3Gibberellin receptor GID1A30.453
3oibFDAPutative acyl-CoA dehydrogenase/0.453
3t4eNADQuinate/shikimate dehydrogenase/0.453
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.453
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.453
4nbwNADShort-chain dehydrogenase/reductase SDR/0.453
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4uxxACPDiacylglycerol kinase2.7.1.1070.453
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1i59ANPChemotaxis protein CheA2.7.13.30.452
1t85CAMCamphor 5-monooxygenase1.14.15.10.452
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.452
1vyrFMNPentaerythritol tetranitrate reductase/0.452
2abjPLPBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.452
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.452
2c20NADUDP-glucose 4-epimerase/0.452
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.452
3cukFADD-amino-acid oxidase1.4.3.30.452
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
3em3478Gag-Pol polyprotein3.4.23.160.452
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.452
4dbc3QPAspartate aminotransferase2.6.1.10.452
4dptAGSMevalonate diphosphate decarboxylase/0.452
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.452
4m9aFDAAcyl-CoA dehydrogenase/0.452
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.452
4qysPLRTryptophan synthase beta chain 24.2.1.200.452
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.452
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.452
5dp2NAPCurF/0.452
1dyjDDFDihydrofolate reductase1.5.1.30.451
1toiHCIAspartate aminotransferase2.6.1.10.451
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.451
2cy0NAPShikimate dehydrogenase (NADP(+))/0.451
2h23SAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.451
2he5NDPAldo-keto reductase family 1 member C211.1.10.451
2j4kU5PUridylate kinase2.7.4.220.451
2qboCAMCamphor 5-monooxygenase1.14.15.10.451
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.451
2vwqNAPGlucose 1-dehydrogenase/0.451
3fwiCAMCamphor 5-monooxygenase1.14.15.10.451
3ixp834Ecdysone receptor/0.451
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4rnwFMNNADPH dehydrogenase 11.6.99.10.451
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.451
1ddsMTXDihydrofolate reductase1.5.1.30.450
1dhiMTXDihydrofolate reductase1.5.1.30.450
1fmjRTLRetinol dehydratase/0.450
1m78NDPDihydrofolate reductase1.5.1.30.450
1skmSAHModification methylase HhaI2.1.1.370.450
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.450
1yetGDMHeat shock protein HSP 90-alpha/0.450
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.450
2feuCAMCamphor 5-monooxygenase1.14.15.10.450
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.450
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.450
2rqfJH3Hemolymph juvenile hormone binding protein/0.450
2v16C47Renin3.4.23.150.450
3asjXYNHomoisocitrate dehydrogenase/0.450
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.450
3fr4F8AFatty acid-binding protein, adipocyte/0.450
3gvhNADMalate dehydrogenase/0.450
3h2cB58Dihydropteroate synthase/0.450
3lcjCOAPhosphopantetheine adenylyltransferase/0.450
4blrUTPNTPase P4/0.450
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.450
4cdmFO1Deoxyribodipyrimidine photolyase/0.450
4j16NADNAD/NADP transhydrogenase alpha subunit 1/0.450
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.450
4q73FADBifunctional protein PutA/0.450
4wudANPDNA gyrase subunit B/0.450
5bsfNADPyrroline-5-carboxylate reductase/0.450
1dgmADNAdenosine kinase2.7.1.200.449
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.449
1kvtUPGUDP-glucose 4-epimerase5.1.3.20.449
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.449
1ra3MTXDihydrofolate reductase1.5.1.30.449
1tqf32PBeta-secretase 13.4.23.460.449
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.449
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.449
2qtvGNPSmall COPII coat GTPase SAR13.6.50.449
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
3gbuATPUncharacterized sugar kinase PH14592.7.10.449
3h06VBPGlutamate receptor 2/0.449
3lxiCAMCytochrome P450/0.449
3nl6TPSUncharacterized protein/0.449
3oxv478Gag-Pol polyprotein3.4.23.160.449
3smkCW714-3-3 protein sigma/0.449
4ap3NAPSteroid monooxygenase/0.449
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.449
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.449
4k0tD9ZCarbonic anhydrase 24.2.1.10.449
4lol1YEStimulator of interferon genes protein/0.449
4q71FADBifunctional protein PutA/0.449
4x5gFOLDihydrofolate reductase1.5.1.30.449
5i4nATPTyrosine-protein kinase JAK2/0.449
4ej4EJ4Delta-type opioid receptor/0.449
1culFOKAdenylate cyclase type 2/0.448
1culFOKAdenylate cyclase type 5/0.448
1g41ADPATP-dependent protease ATPase subunit HslU/0.448
1guyNADMalate dehydrogenase/0.448
1hbvGANGag-Pol polyprotein/0.448
1nhhANPDNA mismatch repair protein MutL/0.448
1uyuCAMCamphor 5-monooxygenase1.14.15.10.448
2e08SAHDiphthine synthase/0.448
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.448
2hutSAHDiphthine synthase/0.448
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.448
3a13CAPRibulose bisphosphate carboxylase/0.448
3a8tATPAdenylate isopentenyltransferase/0.448
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.448
3zznADPL-lactate dehydrogenase/0.448
4c77N01Phenylacetone monooxygenase1.14.13.920.448
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.448
4kwhNAPReductase homolog/0.448
4xgxADPFAD:protein FMN transferase/0.448
1ae1NAPTropinone reductase 1/0.447
1gvhFADFlavohemoprotein/0.447
1w48APCNTPase P4/0.447
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.447
2c27ACOMycothiol acetyltransferase2.3.1.1890.447
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.447
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.447
2qnqQN3Gag-Pol polyprotein3.4.23.160.447
3c15GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.447
3fwjCAMCamphor 5-monooxygenase1.14.15.10.447
3lzs017Gag-Pol polyprotein3.4.23.160.447
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.447
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.447
4dpy2P0Mevalonate diphosphate decarboxylase/0.447
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.447
4ke11R6Beta-secretase 13.4.23.460.447
4kgmATPUncharacterized protein/0.447
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.447
5djtFMNNPH1-2/0.447
5hi6MTXDihydrofolate reductase/0.447
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.446
1oc1ASVIsopenicillin N synthase1.21.3.10.446
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1qr6NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.446
2emrSAHDiphthine synthase/0.446
2fy4COACholine O-acetyltransferase2.3.1.60.446
2huxSAHDiphthine synthase/0.446
2owgSAHDiphthine synthase/0.446
2ylzFADPhenylacetone monooxygenase1.14.13.920.446
2z6rSAHDiphthine synthase/0.446
3muoZPRProlyl endopeptidase/0.446
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.446
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.446
4b1uLABActin, alpha skeletal muscle/0.446
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.446
4lx9ACON-alpha-acetyltransferase2.3.10.446
4mwhATPCasein kinase II subunit alpha2.7.11.10.446
4o2rGDPGTP-binding protein Rheb/0.446
4qxq1YEStimulator of interferon genes protein/0.446
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
5ez4NADBetaine-aldehyde dehydrogenase/0.446
1cjuFOKAdenylate cyclase type 2/0.445
1cjuFOKAdenylate cyclase type 5/0.445
1drbMTXDihydrofolate reductase1.5.1.30.445
1mvtDTMDihydrofolate reductase1.5.1.30.445
1n3sGTPGTP cyclohydrolase 13.5.4.160.445
1ol7ADPAurora kinase A2.7.11.10.445
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.445
1vyw292Cyclin-dependent kinase 22.7.11.220.445
2aa3AP0L-lactate dehydrogenase/0.445
2bpoNAPNADPH--cytochrome P450 reductase/0.445
2e0nSAHPrecorrin-2 C20-methyltransferase/0.445
2e1zB4PPropionate kinase/0.445
2eh2SAHDiphthine synthase/0.445
2eklNADD-3-phosphoglycerate dehydrogenase/0.445
2j08FADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.445
2q46NAPUncharacterized protein At5g02240/0.445
3fstFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.445
3phiNDPShikimate dehydrogenase (NADP(+))/0.445
3s1dZIRCytokinin dehydrogenase 11.5.99.120.445
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.445
3w1qYRODihydroorotate dehydrogenase (fumarate)1.3.98.10.445
4a6nFADTetX family tetracycline inactivation enzyme/0.445
4b4w9L9Bifunctional protein FolD/0.445
4bfwZVWPantothenate kinase2.7.1.330.445
4fwfFADLysine-specific histone demethylase 1B10.445
4kgkGTPUncharacterized protein/0.445
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1l8aTDPPyruvate dehydrogenase E1 component1.2.4.10.444
1mj9COAHistone acetyltransferase ESA1/0.444
1pd9CO4Dihydrofolate reductase1.5.1.30.444
1t88CAMCamphor 5-monooxygenase1.14.15.10.444
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.444
1wvgCXYCDP-glucose 4,6-dehydratase4.2.1.450.444
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.444
2b8tTHMThymidine kinase/0.444
2balPQAMitogen-activated protein kinase 14/0.444
2bi8FADUDP-galactopyranose mutase5.4.99.90.444
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2e8qSAHDiphthine synthase/0.444
2pwcG3GGag-Pol polyprotein3.4.23.160.444
2w6zL21Biotin carboxylase6.3.4.140.444
2x06NADL-sulfolactate dehydrogenase/0.444
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.444
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.444
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.444
3se5ANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.444
3sptUD1Bifunctional protein GlmU/0.444
3vx4ATPPutative ABC transporter, ATP-binding protein ComA/0.444
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
4bfxZVXPantothenate kinase2.7.1.330.444
4cukNAID-lactate dehydrogenase/0.444
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.444
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.444
5dg3U21Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase/0.444
1bw9NADPhenylalanine dehydrogenase/0.443
1dz4CAMCamphor 5-monooxygenase1.14.15.10.443
1g4oBSBCarbonic anhydrase 24.2.1.10.443
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.443
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.443
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.443
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.443
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.443
2itnANPEpidermal growth factor receptor2.7.10.10.443
2q7vFADThioredoxin reductase/0.443
2qd8065Gag-Pol polyprotein3.4.23.160.443
2zjwREFCasein kinase II subunit alpha2.7.11.10.443
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.443
3fwyADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein/0.443
3gkaFMNN-ethylmaleimide reductase/0.443
3in6FMNUncharacterized protein/0.443
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.443
3mjrAC2Deoxycytidine kinase2.7.1.740.443
3rqqBA3ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.443
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.443
3toh079Gag-Pol polyprotein2.7.7.490.443
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
4cf7ADPAdenylate kinase/0.443
4n9iPCGCatabolite expression activator/0.443
4yqfGDPSeptin-9/0.443
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
4ztvTA7Anthranilate phosphoribosyltransferase/0.443
5a9sNAPPutative dehydrogenase/0.443
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.443
1hkuNADC-terminal-binding protein 11.1.10.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1j5pNADL-aspartate dehydrogenase1.4.1.210.442
1jzqILAIsoleucine--tRNA ligase6.1.1.50.442
1kfcIPLTryptophan synthase alpha chain/0.442
1lbcCYZGlutamate receptor 2/0.442
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.442
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.442
1vbiNADMalate/L-lactate dehydrogenase family protein/0.442
1wngSAHDiphthine synthase/0.442
2bi4NADLactaldehyde reductase1.1.1.770.442
2cvwGDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.442
2ed5SAHDiphthine synthase/0.442
2hu2NADC-terminal binding protein 1/0.442
2pcmSAHDiphthine synthase/0.442
2rkvZBATrichothecene 3-O-acetyltransferase/0.442
2tpsTPSThiamine-phosphate synthase/0.442
2vcmM11Isopenicillin N synthase1.21.3.10.442
2y3rTRKTamL/0.442
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.442
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
3s8cCDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.442
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.442
3ziuLSSLeucyl-tRNA synthetase/0.442
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4bzqADPBifunctional enzyme CysN/CysC2.7.1.250.442
4dieC5PCytidylate kinase/0.442
4djaFAD(6-4) photolyase/0.442
4dxhNAJAlcohol dehydrogenase E chain1.1.1.10.442
4e2bFMNDehydrogenase/0.442
4ek1CAMCamphor 5-monooxygenase1.14.15.10.442
4eqrFADCoenzyme A disulfide reductase/0.442
4i8zG08Gag-Pol polyprotein3.4.23.160.442
4okw198Androgen receptor/0.442
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
5cyoGDPSeptin-9/0.442
1bdlIM1Gag-Pol polyprotein3.4.23.160.441
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1i58ADPChemotaxis protein CheA2.7.13.30.441
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.441
1touB1VFatty acid-binding protein, adipocyte/0.441
2cvqNDPMalate dehydrogenase/0.441
2ek4SAHDiphthine synthase/0.441
2givACOHistone acetyltransferase KAT8/0.441
2hfuMEVMevalonate kinase/0.441
2owuSAHDiphthine synthase/0.441
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.441
3d91REMRenin3.4.23.150.441
3dc3AZMCarbonic anhydrase 24.2.1.10.441
3e6yCW114-3-3-like protein C/0.441
3jvvACPTwitching mobility protein/0.441
3pwm017Gag-Pol polyprotein3.4.23.160.441
3r4b74TGag-Pol polyprotein/0.441
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4dbzNDPPutative ketoacyl reductase1.3.10.441
4ewqMWLMitogen-activated protein kinase 14/0.441
4i231C9Epidermal growth factor receptor2.7.10.10.441
4nmdFDABifunctional protein PutA/0.441
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.441
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.441
5dhhDGWNociceptin receptor/0.441
1adfTADAlcohol dehydrogenase E chain1.1.1.10.440
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.440
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.440
1byqADPHeat shock protein HSP 90-alpha/0.440
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.440
1g4tFTPThiamine-phosphate synthase/0.440
1h73ANPHomoserine kinase2.7.1.390.440
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.440
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.440
1pq944BOxysterols receptor LXR-beta/0.440
1vi2NADQuinate/shikimate dehydrogenase/0.440
1xe55FEPlasmepsin-23.4.23.390.440
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2ekaSAHDiphthine synthase/0.440
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.440
2gesCOKPantothenate kinase2.7.1.330.440
2h2jSFGRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.440
2ien017Gag-Pol polyprotein3.4.23.160.440
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.440
2p6iSAHDiphthine synthase/0.440
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.440
2yegXQGHeat shock protein HSP 90-alpha/0.440
2z6dFMNPhototropin-22.7.11.10.440
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.440
3ekrPY9Heat shock protein HSP 90-alpha/0.440
3elePLPAminotransferase/0.440
3enkUPGUDP-glucose 4-epimerase/0.440
3epoMP5Phosphomethylpyrimidine synthase/0.440
3gonANPPhosphomevalonate kinase/0.440
3h6vNS6Glutamate receptor 2/0.440
3k6l2BBPeptide deformylase3.5.1.880.440
3o15IFPThiamine-phosphate synthase/0.440
3pj8404Cyclin-dependent kinase 22.7.11.220.440
3pzrNAPAspartate-semialdehyde dehydrogenase 1/0.440
3rlq3RQHeat shock protein HSP 90-alpha/0.440
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
3wswNADL-lactate dehydrogenase/0.440
4a862ANMajor pollen allergen Bet v 1-A/0.440
4bfsZVSPantothenate kinase2.7.1.330.440
4i02CMPcAMP-activated global transcriptional regulator CRP/0.440
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.440
4oztP1AEcdysone receptor, putative/0.440
4relKMPGlycosyltransferase/0.440
4u0mGTPCyclic GMP-AMP synthase/0.440
4xvuATPATPase GET3/0.440
4y35F90Endothiapepsin3.4.23.220.440
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.440
5dn3ATPAurora kinase A2.7.11.10.440
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.440