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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4gdaBTNStreptavidin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4gdaBTNStreptavidin/1.000
3ry2BTNStreptavidin/0.691
2rtgBTNStreptavidin/0.657
1srgMHBStreptavidin/0.647
4bx7B4FStreptavidin/0.646
2izfBTNStreptavidin/0.644
2rtnIMIStreptavidin/0.640
1stpBTNStreptavidin/0.634
1lcwSHMStreptavidin/0.632
1sreHABStreptavidin/0.632
2izgBTNStreptavidin/0.628
2rteBTNStreptavidin/0.628
2izlIMIStreptavidin/0.626
2izhBTNStreptavidin/0.625
1mk5BTNStreptavidin/0.623
2rtoIMIStreptavidin/0.622
2rtdBTNStreptavidin/0.621
2rtfBTNStreptavidin/0.618
1rxhBNIStreptavidin/0.616
4dneDTBStreptavidin/0.615
1lczBH7Streptavidin/0.611
3wznBTNStreptavidin/0.610
2rtpIMIStreptavidin/0.609
1srjNABStreptavidin/0.608
1i9hBNIStreptavidin/0.607
1sriDMBStreptavidin/0.602
2y3fBTNStreptavidin/0.602
2rtqIMIStreptavidin/0.600
1swtBTNStreptavidin/0.599
2aviBTNAvidin/0.598
3wyqBTNStreptavidin/0.597
1srfMTBStreptavidin/0.589
1df8BTNStreptavidin/0.585
1luqBTNStreptavidin/0.584
2fhlBNIAvidin-related protein 4/5/0.579
1srhMOBStreptavidin/0.578
2c4iBTNAvidin/0.578
2uywBTNAvd protein/0.578
4bcsBTNAvidin-related protein 4/5/0.577
1y52BTNAvidin-related protein 4/5/0.575
2fhnBNIAvidin-related protein 4/5/0.575
2rtiGLLStreptavidin/0.575
3rdqDTBStreptavidin/0.573
2iziBTNStreptavidin/0.568
4z28BTNHoefavidin/0.568
2izjBTNStreptavidin/0.566
1nqmBTNStreptavidin/0.563
2rtrIMIStreptavidin/0.563
3ew2BTNHypothetical conserved protein/0.561
1avdBTNAvidin/0.558
2izkGLLStreptavidin/0.557
1sweBTNStreptavidin/0.555
2rtmIMIStreptavidin/0.544
1swpBTQStreptavidin/0.543
1nc9IMIStreptavidin/0.540
2uz2BTNAvd protein/0.533
1swnBTNStreptavidin/0.528
2rtkGLLStreptavidin/0.528
3t2wBTNAvidin/streptavidin/0.522
4bb3KKAIsopenicillin N synthase1.21.3.10.521
1n43BTNStreptavidin/0.513
3c3xNAPEugenol synthase 11.1.1.3180.513
1swrBTNStreptavidin/0.512
2a5c8DAAvidin/0.512
4psbGA3Cytokinin-specific binding protein/0.505
2rtlIMIStreptavidin/0.504
1swpBTNStreptavidin/0.501
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.501
1mepBTNStreptavidin/0.499
3bk2U5PRibonuclease J/0.499
4gd9BTNStreptavidin/0.499
2flhZEACytokinin-specific binding protein/0.496
1ndjBTNStreptavidin/0.494
1swdBTNStreptavidin/0.494
2zbaZBATrichothecene 3-O-acetyltransferase/0.494
2tohHBITyrosine 3-monooxygenase1.14.16.20.492
4q0kGA3Phytohormone-binding protein/0.491
3h3sH15Collagen type IV alpha-3-binding protein/0.490
1n9mBTNStreptavidin/0.487
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.487
4bj8BTNAvidin/0.486
4rn615UProthrombin3.4.21.50.486
2y6fM9FIsopenicillin N synthase1.21.3.10.485
4du82P0Mevalonate diphosphate decarboxylase/0.485
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.484
1qiqACCIsopenicillin N synthase1.21.3.10.484
3eksCY9Actin-5C/0.484
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.484
2zjwREFCasein kinase II subunit alpha2.7.11.10.483
4abkAR6Poly [ADP-ribose] polymerase 142.4.2.300.482
4a81DXCMajor pollen allergen Bet v 1-A/0.481
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.480
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.480
2bu9HFVIsopenicillin N synthase1.21.3.10.479
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.479
2pksG44Prothrombin3.4.21.50.478
1kt6RTLRetinol-binding protein 4/0.477
1eioGCHGastrotropin/0.476
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.475
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.475
4fxy0W2Neurolysin, mitochondrial3.4.24.160.475
1r2jFADFkbI/0.474
2jgsBTNAvidin/0.474
2zscBTNTamavidin2/0.474
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.474
4aosFADSteroid monooxygenase/0.474
1gj4132Prothrombin3.4.21.50.473
3arvSAUChitinase A/0.473
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.473
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.473
1fmlRTLRetinol dehydratase/0.472
2vbdV10Isopenicillin N synthase1.21.3.10.472
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.472
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.472
4a862ANMajor pollen allergen Bet v 1-A/0.472
1trgCB3Thymidylate synthase/0.470
2r5nTPPTransketolase 1/0.470
3gwfFADCyclohexanone monooxygenase/0.470
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.470
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.469
1kt7RTLRetinol-binding protein 4/0.469
1ot7IU5Bile acid receptor/0.469
4yvbBTNStreptavidin/0.469
1lkeDOGBilin-binding protein/0.468
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.468
2xy93ESAngiotensin-converting enzyme3.2.10.468
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.468
4a83DXCMajor pollen allergen Bet v 1-A/0.468
3sn6P0GBeta-2 adrenergic receptor/0.468
1mrqSTRAldo-keto reductase family 1 member C1/0.467
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
4dpy2P0Mevalonate diphosphate decarboxylase/0.467
4dz7D02Carbonic anhydrase 24.2.1.10.467
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.467
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.466
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1tj0FADBifunctional protein PutA1.5.5.20.466
1wsvTHHAminomethyltransferase, mitochondrial/0.466
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
2jb4A14Isopenicillin N synthase1.21.3.10.466
2y60M8FIsopenicillin N synthase1.21.3.10.466
3mqe416Prostaglandin G/H synthase 21.14.99.10.466
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.466
3wypBSOStreptavidin/0.466
3zkyWT4Isopenicillin N synthase1.21.3.10.466
5cmx0G6Prothrombin3.4.21.50.466
1jtqLY3Thymidylate synthase/0.465
1obnASVIsopenicillin N synthase1.21.3.10.465
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.465
2gvdFKPAdenylate cyclase type 2/0.465
2gvdFKPAdenylate cyclase type 5/0.465
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.465
4a8v2ANMajor pollen allergen Bet v 1-J/0.465
1w6hTITPlasmepsin-23.4.23.390.464
2impNAILactaldehyde dehydrogenase1.2.1.220.464
3ekuCY9Actin-5C/0.464
3p3zP3ZPutative cytochrome P450/0.464
3up3XCAaceDAF-12/0.464
4oztP1AEcdysone receptor, putative/0.464
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.464
1vbiNADMalate/L-lactate dehydrogenase family protein/0.463
3af0GDPPantothenate kinase2.7.1.330.463
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4xd1T3QQdtf/0.463
5irnADPNucleotide binding oligomerization domain containing 2/0.463
1p8dCO1Oxysterols receptor LXR-beta/0.462
2xveFADPutative flavin-containing monooxygenase/0.462
4ure1PSCyclohexanol dehydrogenase/0.462
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.462
1jtuLYBThymidylate synthase/0.461
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.461
1uzwCDHIsopenicillin N synthase1.21.3.10.461
2v58LZJBiotin carboxylase6.3.4.140.461
3bg7FADPyranose 2-oxidase/0.461
3rdoBTNStreptavidin/0.461
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.461
1amoFADNADPH--cytochrome P450 reductase/0.460
1hb1OCVIsopenicillin N synthase1.21.3.10.460
1pqc444Oxysterols receptor LXR-beta/0.460
3bhrTHGThymidylate synthase/0.460
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.460
4gevCB3Thymidylate synthase/0.460
1gj5130Prothrombin3.4.21.50.459
2npfMOUElongation factor 2/0.459
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3f3sNADLambda-crystallin homolog/0.459
4l1xSTRAldo-keto reductase family 1 member C2/0.459
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.459
1cqp803Integrin alpha-L/0.458
1e7aPFLSerum albumin/0.458
1xddAAYIntegrin alpha-L/0.458
1z6tADPApoptotic protease-activating factor 1/0.458
2h55DZ8Heat shock protein HSP 90-alpha/0.458
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
2zhw12UProthrombin3.4.21.50.458
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.458
3owuEQUSteroid Delta-isomerase5.3.3.10.458
3rimTPPTransketolase2.2.1.10.458
4othDRNSerine/threonine-protein kinase N1/0.458
4rtsSAMDNA adenine methylase2.1.1.720.458
5fm7ADPRuvB-like helicase/0.458
1blzACVIsopenicillin N synthase1.21.3.10.457
1bwlFMNNADPH dehydrogenase 11.6.99.10.457
1m78NDPDihydrofolate reductase1.5.1.30.457
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3bl7DD1m7GpppX diphosphatase3.6.1.590.457
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.457
3sp9IL2Peroxisome proliferator-activated receptor delta/0.457
4c6zTLE3-oxoacyl-ACP synthase/0.457
4ggzBTNBll1558 protein/0.457
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.457
4pd6URINucleoside permease/0.457
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.457
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
3af1GDPPantothenate kinase2.7.1.330.456
3fywXCFDihydrofolate reductase1.5.1.30.456
3vf60H6Glucokinase2.7.1.20.456
4fqsLYAThymidylate synthase ThyA/0.456
4kbyC2EStimulator of interferon genes protein/0.456
4qe6JN3Bile acid receptor/0.456
4twnB96Ephrin type-A receptor 32.7.10.10.456
1culFOKAdenylate cyclase type 2/0.455
1culFOKAdenylate cyclase type 5/0.455
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.455
1psa0ZLPepsin A3.4.23.10.455
1sb1165Prothrombin3.4.21.50.455
1trkTPPTransketolase 12.2.1.10.455
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.455
2vmyFFOSerine hydroxymethyltransferase/0.455
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.455
3cehAVEGlycogen phosphorylase, liver form2.4.1.10.455
3jziJZLBiotin carboxylase6.3.4.140.455
3maaFKPAdenylate cyclase type 2/0.455
3maaFKPAdenylate cyclase type 5/0.455
4dliIRGMitogen-activated protein kinase 14/0.455
4k4eK4ETankyrase-12.4.2.300.455
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.455
5efwFMNNPH1-1/0.455
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.454
1h65GDPTranslocase of chloroplast 343.6.50.454
1qjfACSIsopenicillin N synthase1.21.3.10.454
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.454
1v35NAIEnoyl-ACP reductase/0.454
1zg32HIIsoflavone 4'-O-methyltransferase/0.454
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4cukNAID-lactate dehydrogenase/0.454
4mv1ADPBiotin carboxylase6.3.4.140.454
5epvACPBlue-light-activated histidine kinase2.7.13.30.454
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.453
1me6IVSPlasmepsin-23.4.23.390.453
1nbiSAMGlycine N-methyltransferase2.1.1.200.453
1osvCHCBile acid receptor/0.453
1pq944BOxysterols receptor LXR-beta/0.453
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.453
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.453
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
2w9hTOPDihydrofolate reductase1.5.1.30.453
3elm24FCollagenase 33.4.240.453
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
3lqfNADGalactitol dehydrogenase/0.453
3vgwNVZAvidin/0.453
4avlTMPPolymerase acidic protein/0.453
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.453
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.453
1axwMTXThymidylate synthase/0.452
1bq1CB3Thymidylate synthase/0.452
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.452
1hb3SCVIsopenicillin N synthase1.21.3.10.452
1lf2R37Plasmepsin-23.4.23.390.452
1tysDHFThymidylate synthase/0.452
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.452
1zdwFLVPrenyltransferase/0.452
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.452
2ejvNADL-threonine 3-dehydrogenase/0.452
2ghlLIBMitogen-activated protein kinase 14/0.452
2powI7CCarbonic anhydrase 24.2.1.10.452
2vjmCOAFormyl-CoA:oxalate CoA-transferase/0.452
3qm4PN0Cytochrome P450 2D6/0.452
3zdu38RCyclin-dependent kinase-like 32.7.11.220.452
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.452
4hl515WTankyrase-22.4.2.300.452
4kko1REGag-Pol polyprotein2.7.7.490.452
2cdaNAPGlucose 1-dehydrogenase/0.451
2fj1CTCTetracycline repressor protein class D/0.451
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
3icpNADNAD-dependent epimerase/dehydratase/0.451
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.451
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.451
3mytEQUSteroid Delta-isomerase5.3.3.10.451
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.451
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.451
3vrbFTNSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.451
3vrbFTNCytochrome b-large subunit/0.451
4dz5NAPAldo-keto reductase family 1 member C3/0.451
4k6mSAHGenome polyprotein/0.451
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.451
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.451
5dcyNAPIridoid synthase1.3.1.990.451
1c7oPPGHemolysin/0.450
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1kt3RTLRetinol-binding protein 4/0.450
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.450
1thnADPAnti-sigma F factor/0.450
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.450
2j14GNIPeroxisome proliferator-activated receptor delta/0.450
2p5yNADUDP-glucose 4-epimerase/0.450
2q5qKPVIndole-3-pyruvate decarboxylase4.1.1.740.450
2v5aLZLBiotin carboxylase6.3.4.140.450
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.450
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.450
3f0rTSNHistone deacetylase 83.5.1.980.450
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3h3t16HCollagen type IV alpha-3-binding protein/0.450
3ixp834Ecdysone receptor/0.450
3up0D7SaceDAF-12/0.450
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.450
4eb5PLPCysteine desulfurase IscS 2/0.450
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.450
4m83ERYOleandomycin glycosyltransferase2.4.10.450
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.450
5emhNAPIridoid synthase1.3.1.990.450
1kziTHGThymidylate synthase/0.449
1mvtDTMDihydrofolate reductase1.5.1.30.449
1n0uSO1Elongation factor 2/0.449
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.449
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2b35NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2x7hPFNProstaglandin reductase 310.449
2yg3FADPutrescine oxidase/0.449
3f63GTXGlutathione transferase GST1-4/0.449
3fznD7KBenzoylformate decarboxylase4.1.1.70.449
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.449
3lkhLT6Genome polyprotein2.7.7.480.449
3nr4PYVAbscisic acid receptor PYL2/0.449
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.449
4bfxZVXPantothenate kinase2.7.1.330.449
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.449
4kwhNAPReductase homolog/0.449
4rrgA3TThreonine--tRNA ligase6.1.1.30.449
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.449
1itzTPPTransketolase, chloroplastic2.2.1.10.448
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.448
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.448
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2x9dITCTetracycline repressor protein class D/0.448
2xvv9DNSerum albumin/0.448
2z3uCRRCytochrome P450/0.448
3bw4FMNPutative 2-nitropropane dioxygenase/0.448
3dds26BGlycogen phosphorylase, liver form2.4.1.10.448
3ewkFADSensory box histidine kinase/response regulator/0.448
3vtdTKDVitamin D3 receptor/0.448
4az29MUProthrombin3.4.21.50.448
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.448
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.448
4y9lFADAcyl-CoA dehydrogenase family member 11/0.448
8catNDPCatalase1.11.1.60.448
1cjtFOKAdenylate cyclase type 2/0.447
1cjtFOKAdenylate cyclase type 5/0.447
1dyrTOPDihydrofolate reductase1.5.1.30.447
1f4gTP4Thymidylate synthase/0.447
1kvkATPMevalonate kinase2.7.1.360.447
1ldqSHMAvidin/0.447
1oc1ASVIsopenicillin N synthase1.21.3.10.447
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.447
2a2sGSNGlutathione S-transferase P2.5.1.180.447
2bdyUNBProthrombin3.4.21.50.447
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.447
2nr4FMNConserved protein/0.447
2q4wFADCytokinin dehydrogenase 71.5.99.120.447
3gwfNAPCyclohexanone monooxygenase/0.447
3h3r14HCollagen type IV alpha-3-binding protein/0.447
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3n8yDIFProstaglandin G/H synthase 11.14.99.10.447
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
4ceqQCHIntegrase/0.447
4i8vBHFCytochrome P450 1A11.14.14.10.447
4jbtASDCytochrome P450 monooxygenase/0.447
4zu44TGWxcM-like protein/0.447
1e7qNAPGDP-L-fucose synthase/0.446
1fvpFMANon-fluorescent flavoprotein/0.446
1i75NOJCyclomaltodextrin glucanotransferase2.4.1.190.446
1l8aTDPPyruvate dehydrogenase E1 component1.2.4.10.446
1o2g696Prothrombin3.4.21.50.446
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.446
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.446
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.446
2on6IMHPurine nucleoside phosphorylase2.4.2.10.446
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.446
2qw8NAPEugenol synthase 11.1.1.3180.446
2vbpVB1Isopenicillin N synthase1.21.3.10.446
2wdqCBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.446
2wdqCBESuccinate dehydrogenase cytochrome b556 subunit/0.446
2xviFADPutative flavin-containing monooxygenase/0.446
3nguADPNucleoside diphosphate kinase/0.446
3p8jFMNPentaerythritol tetranitrate reductase/0.446
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.446
3vhhVHHAvidin/0.446
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.446
4bquCLRJapanin/0.446
4mv8ACPBiotin carboxylase6.3.4.140.446
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.446
4zj8SUVOrexin receptor type 1/0.446
1h22E10Acetylcholinesterase3.1.1.70.445
1hquHBYGag-Pol polyprotein2.7.7.490.445
1nm6L86Prothrombin3.4.21.50.445
1pl6572Sorbitol dehydrogenase1.1.1.140.445
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.445
2bxqIMNSerum albumin/0.445
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.445
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.445
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2rlcCHDCholoylglycine hydrolase3.5.1.240.445
2v59LZKBiotin carboxylase6.3.4.140.445
3jpuTY4Transcriptional activator protein LasR/0.445
3pd2A3SThreonine--tRNA ligase6.1.1.30.445
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.445
4bfwZVWPantothenate kinase2.7.1.330.445
4gdcNDPUDP-galactopyranose mutase/0.445
4ipw1G7Mycocyclosin synthase1.14.21.90.445
4mihFADPyranose 2-oxidase1.1.3.100.445
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.445
4rrxLURProstaglandin G/H synthase 21.14.99.10.445
4tjy3GNTankyrase-22.4.2.300.445
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.445
1bk0ACVIsopenicillin N synthase1.21.3.10.444
1dgmADNAdenosine kinase2.7.1.200.444
1j9zFADNADPH--cytochrome P450 reductase/0.444
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1nzq162Prothrombin3.4.21.50.444
1pu9COAHAT A1/0.444
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1yvfPH7Polyprotein/0.444
2acwUPGGlycosyltransferase/0.444
2ofv242Tyrosine-protein kinase Lck2.7.10.20.444
2r9w23CBeta-lactamase3.5.2.60.444
2vczVC3Hematopoietic prostaglandin D synthase/0.444
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3f0aACOSpermidine N(1)-acetyltransferase/0.444
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3owyEQUSteroid Delta-isomerase5.3.3.10.444
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.444
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.444
3zc3NAPFerredoxin--NADP reductase1.18.1.20.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.444
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.444
5cb3APRO-acetyl-ADP-ribose deacetylase/0.444
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.444
4s0vSUVOrexin receptor type 2/0.444
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.443
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.443
1mp0NADAlcohol dehydrogenase class-31.1.1.10.443
1qo8FADFumarate reductase flavoprotein subunit/0.443
1rftPXMPyridoxal kinase2.7.1.350.443
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.443
1tqf32PBeta-secretase 13.4.23.460.443
2dvlFADAcyl-CoA dehydrogenase/0.443
2pixDHTAndrogen receptor/0.443
2w6pOA4Biotin carboxylase6.3.4.140.443
2xlsFADPutative flavin-containing monooxygenase/0.443
2xluNA7Putative flavin-containing monooxygenase/0.443
2yg4FADPutrescine oxidase/0.443
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.443
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3qlrNDPDihydrofolate reductase1.5.1.30.443
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.443
3u8hBHPPhospholipase A2, membrane associated/0.443
4a84DXCMajor pollen allergen Bet v 1-A/0.443
4b63NAPL-ornithine N(5)-monooxygenase/0.443
5a3cNADSIR2 family protein/0.443
1cjkFOKAdenylate cyclase type 2/0.442
1cjkFOKAdenylate cyclase type 5/0.442
1dr3HBIDihydrofolate reductase1.5.1.30.442
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.442
1h50FMNPentaerythritol tetranitrate reductase/0.442
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1rszDIHPurine nucleoside phosphorylase2.4.2.10.442
1rx1NAPDihydrofolate reductase1.5.1.30.442
1tl7FOKAdenylate cyclase type 2/0.442
1tl7FOKAdenylate cyclase type 5/0.442
1vrwNAIEnoyl-ACP reductase/0.442
2gjlFMNNitronate monooxygenase1.13.12.160.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.442
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.442
3djfBC3Purine nucleoside phosphorylase/0.442
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.442
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.442
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3p8iFMNPentaerythritol tetranitrate reductase/0.442
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.442
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.442
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.442
4ambDUDPutative glycosyl transferase/0.442
4bfuZVUPantothenate kinase2.7.1.330.442
4c73TLH3-oxoacyl-ACP synthase/0.442
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.442
4jlj1NMDeoxycytidine kinase2.7.1.740.442
4prxADPDNA gyrase subunit B/0.442
4rrfA3SThreonine--tRNA ligase6.1.1.30.442
4s1iPLPPyridoxal kinase, putative/0.442
5iu86DZAdenosine receptor A2a/0.442
1be4PCGNucleoside diphosphate kinase A 22.7.4.60.441
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.441
1p0hCOAMycothiol acetyltransferase2.3.1.1890.441
1sq5ADPPantothenate kinase2.7.1.330.441
1ykdCMPAdenylate cyclase/0.441
2vn1FK5Peptidylprolyl isomerase/0.441
2w6qOA5Biotin carboxylase6.3.4.140.441
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.441
3aosJH2Hemolymph juvenile hormone binding protein/0.441
3atyFMNProstaglandin F2a synthase/0.441
3fhxPLPPyridoxal kinase2.7.1.350.441
3pd4A3GThreonine--tRNA ligase6.1.1.30.441
3qfcNAPNADPH--cytochrome P450 reductase/0.441
3rvhHQ2Lysine-specific demethylase 4A1.14.110.441
4dch4DCGlucokinase2.7.1.20.441
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.441
4n1gCEIObelin/0.441
4n3l2FNProthrombin3.4.21.50.441
4wasCOOEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
1dtpAPUDiphtheria toxin/0.440
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.440
1ly4COQDihydrofolate reductase1.5.1.30.440
1qgyFADFerredoxin--NADP reductase1.18.1.20.440
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1ypkCCRProthrombin3.4.21.50.440
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.440
2ii3CAOLipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1680.440
2w6oOA3Biotin carboxylase6.3.4.140.440
2xegCI9Glutamate carboxypeptidase 23.4.17.210.440
2y035FWBeta-1 adrenergic receptor/0.440
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
2zgx29UProthrombin3.4.21.50.440
2znq401Peroxisome proliferator-activated receptor delta/0.440
3d4bDZDNAD-dependent protein deacetylase/0.440
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3ehjACPSensor histidine kinase DesK2.7.13.30.440
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.440
3junAKDPhenazine biosynthesis protein A/B/0.440
3nuvASDSteroid Delta-isomerase5.3.3.10.440
3qtv06PProthrombin3.4.21.50.440
3ujlA8SAbscisic acid receptor PYL2/0.440
3v2uATPProtein GAL3/0.440
4bfvZVVPantothenate kinase2.7.1.330.440
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.440
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
5dbfNDPIridoid synthase1.3.1.990.440
7catNDPCatalase1.11.1.60.440