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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4eutBX7Serine/threonine-protein kinase TBK12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4eutBX7Serine/threonine-protein kinase TBK12.7.11.11.000
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.612
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.572
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.565
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.559
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.546
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.546
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.544
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.541
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.541
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.540
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.538
3zh8C58Protein kinase C iota type2.7.11.130.533
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.530
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.530
4e6d0NUTyrosine-protein kinase JAK2/0.529
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.527
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.525
1yvj4STTyrosine-protein kinase JAK32.7.10.20.524
4aqc88ATyrosine-protein kinase JAK2/0.520
4ez50RSCyclin-dependent kinase 62.7.11.220.520
4bbfO19Tyrosine-protein kinase JAK2/0.518
2in6839Wee1-like protein kinase2.7.10.20.517
3lpbNVBTyrosine-protein kinase JAK2/0.516
3zep1NXTyrosine-protein kinase JAK32.7.10.20.516
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.515
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.515
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.514
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.514
4hvi19STyrosine-protein kinase JAK32.7.10.20.514
2vv9IM9Cyclin-dependent kinase 22.7.11.220.513
3zewSTUEphrin type-B receptor 42.7.10.10.513
4ji91M3Tyrosine-protein kinase JAK2/0.511
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.510
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.510
4hge15VTyrosine-protein kinase JAK2/0.510
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.509
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.508
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.508
4ivb1J5Tyrosine-protein kinase JAK1/0.506
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.505
2yn8STUEphrin type-B receptor 42.7.10.10.503
1fvv107Cyclin-dependent kinase 22.7.11.220.502
3i60E86Mitogen-activated protein kinase 12.7.11.240.502
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.502
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.501
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.501
4fv6E57Mitogen-activated protein kinase 12.7.11.240.501
4btjATPTau-tubulin kinase 12.7.11.10.500
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.500
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.499
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.499
4e6q0NVTyrosine-protein kinase JAK2/0.498
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.498
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.497
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.497
2vu3LZECyclin-dependent kinase 22.7.11.220.497
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.497
4y95746Tyrosine-protein kinase/0.497
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.496
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.495
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.494
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.494
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.494
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.494
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.493
3a62STURibosomal protein S6 kinase beta-12.7.11.10.492
3rvg17PTyrosine-protein kinase JAK2/0.492
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.491
4hvh19RTyrosine-protein kinase JAK32.7.10.20.491
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.490
4jia1K3Tyrosine-protein kinase JAK2/0.490
4f081RSTyrosine-protein kinase JAK2/0.489
4i5cC5ITyrosine-protein kinase JAK1/0.489
4o0wADNAurora kinase A2.7.11.10.489
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.488
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
1x8b824Wee1-like protein kinase2.7.10.20.487
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.487
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.487
3at4CCKCasein kinase II subunit alpha2.7.11.10.487
4hvg19QTyrosine-protein kinase JAK32.7.10.20.487
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.486
1u54ACPActivated CDC42 kinase 1/0.486
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.486
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.486
2hog710Serine/threonine-protein kinase Chk12.7.11.10.486
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.486
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.486
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.486
5av2KMPDeath-associated protein kinase 12.7.11.10.486
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
2yaaATPDeath-associated protein kinase 2/0.485
2z2w770Wee1-like protein kinase2.7.10.20.485
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.485
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.485
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.485
3w2rW2REpidermal growth factor receptor2.7.10.10.485
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.485
3iok1P6Tyrosine-protein kinase JAK2/0.484
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
4j95ACPFibroblast growth factor receptor 2/0.484
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.483
4e4n0NLTyrosine-protein kinase JAK1/0.483
4gmy0X5Tyrosine-protein kinase JAK2/0.483
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.482
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.482
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
5av3KMPDeath-associated protein kinase 12.7.11.10.482
5cvfATPCasein kinase II subunit alpha2.7.11.10.482
5dt0SKEAurora kinase A2.7.11.10.482
2ckeIQUDeath-associated protein kinase 2/0.481
3tnwF18Cyclin-dependent kinase 22.7.11.220.481
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.481
4y93746Tyrosine-protein kinase/0.481
1jklANPDeath-associated protein kinase 12.7.11.10.480
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.480
2x6dX6DAurora kinase A2.7.11.10.480
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.480
3rak03ZCyclin-dependent kinase 22.7.11.220.480
4aguD15Cyclin-dependent kinase-like 1/0.480
4axdANPInositol-pentakisphosphate 2-kinase2.7.1.1580.480
4bcmT7ZCyclin-dependent kinase 22.7.11.220.480
3be9P04Casein kinase II subunit alpha2.7.11.10.479
1wvySTUDeath-associated protein kinase 12.7.11.10.478
2fvdLIACyclin-dependent kinase 22.7.11.220.478
3eb0DRKUncharacterized protein/0.478
3nux3NVCyclin-dependent kinase 62.7.11.220.478
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.478
4eooATPCyclin-dependent kinase 22.7.11.220.478
4wkqIREEpidermal growth factor receptor2.7.10.10.478
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.476
1pkdUCNCyclin-dependent kinase 22.7.11.220.476
4dtaADNAPH(2'')-Id/0.476
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.476
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.476
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.476
2j0m4STFocal adhesion kinase 12.7.10.20.475
2q7vFADThioredoxin reductase/0.475
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.475
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.475
3sheI85MAP kinase-activated protein kinase 32.7.11.10.475
4dt9GMPAPH(2'')-Id/0.475
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.474
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.474
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.474
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.473
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2b7aIZATyrosine-protein kinase JAK2/0.473
3gu7ADPDeath-associated protein kinase 12.7.11.10.473
4c62XWWTyrosine-protein kinase JAK2/0.473
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.473
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.473
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.472
2w17I19Cyclin-dependent kinase 22.7.11.220.472
3ggfGVDSerine/threonine-protein kinase 26/0.472
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.472
3q9xEMOCasein kinase II subunit alpha2.7.11.10.472
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.472
2pvnP63Casein kinase II subunit alpha2.7.11.10.471
2vd5BI8Myotonin-protein kinase2.7.11.10.471
3qtrX36Cyclin-dependent kinase 22.7.11.220.471
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.471
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.471
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.471
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.471
1wvxBD4Death-associated protein kinase 12.7.11.10.470
2bqvA1AProtease/0.470
2pvmP29Casein kinase II subunit alpha2.7.11.10.470
4ehzJAKTyrosine-protein kinase JAK1/0.470
5e8ySTUTGF-beta receptor type-22.7.11.300.470
1eh4IC1Casein kinase I homolog 12.7.11.10.469
1k6tXN1Gag-Pol polyprotein3.4.23.160.469
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.469
2eb3ANPEpidermal growth factor receptor2.7.10.10.469
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.469
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.469
3lltANPProtein serine/threonine kinase-1/0.469
3t8oATPRhodopsin kinase/0.469
3zxtACPDeath-associated protein kinase 12.7.11.10.469
4c61LMMTyrosine-protein kinase JAK2/0.469
4jbqVX6Aurora kinase A2.7.11.10.469
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.469
1qmzATPCyclin-dependent kinase 22.7.11.220.468
2uzbC75Cyclin-dependent kinase 22.7.11.220.468
2wipP49Cyclin-dependent kinase 22.7.11.220.468
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.468
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.467
2qo7ANPEphrin type-A receptor 32.7.10.10.467
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.467
2x9dITCTetracycline repressor protein class D/0.467
2zjwREFCasein kinase II subunit alpha2.7.11.10.467
3bhy7CPDeath-associated protein kinase 3/0.467
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.467
4fx360KCyclin-dependent kinase 22.7.11.220.467
4jbpYPHAurora kinase A2.7.11.10.467
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.466
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.466
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.466
3hx4ANPCalmodulin-domain protein kinase 1/0.466
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.466
4hgs15GCasein kinase I isoform gamma-32.7.11.10.466
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.466
3w2sW2REpidermal growth factor receptor2.7.10.10.465
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
4dgnLU2Casein kinase II subunit alpha2.7.11.10.465
1finATPCyclin-dependent kinase 22.7.11.220.464
1pmn984Mitogen-activated protein kinase 102.7.11.240.464
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.464
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.464
3s4qNK0Mitogen-activated protein kinase 14/0.464
4anmWULCasein kinase II subunit alpha2.7.11.10.464
4dgo0JWCasein kinase II subunit alpha2.7.11.10.464
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.464
4gk3L87Ephrin type-A receptor 32.7.10.10.464
4j99ACPFibroblast growth factor receptor 2/0.464
1gqtACPRibokinase/0.463
1k6pXN3Gag-Pol polyprotein3.4.23.160.463
1pxpCK8Cyclin-dependent kinase 22.7.11.220.463
2qoqANPEphrin type-A receptor 32.7.10.10.463
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2vttLZDCyclin-dependent kinase 22.7.11.220.463
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.463
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.463
3s1h56ZCyclin-dependent kinase 22.7.11.220.463
3u4uLNHCasein kinase II subunit alpha2.7.11.10.463
4fv9E71Mitogen-activated protein kinase 12.7.11.240.463
4h3qANPMitogen-activated protein kinase 12.7.11.240.463
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.462
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.462
2csnCKICasein kinase I homolog 12.7.11.10.462
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.462
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.462
3ncz3NCRho-associated protein kinase 12.7.11.10.462
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.462
4fk60UJTyrosine-protein kinase JAK1/0.462
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.462
4jboWPHAurora kinase A2.7.11.10.462
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.462
4lrjANPUncharacterized protein/0.462
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.462
1bygSTUTyrosine-protein kinase CSK/0.461
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1om1IQACasein kinase II subunit alpha2.7.11.10.461
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2w05FRTCyclin-dependent kinase 22.7.11.220.461
3bheBZNGag-Pol polyprotein3.4.23.160.461
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4jnqFDAThioredoxin reductase/0.461
4q5hANPProtein kinase OspG2.70.461
5dosATPAurora kinase A2.7.11.10.461
1aq1STUCyclin-dependent kinase 22.7.11.220.460
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.460
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2henADPEphrin type-B receptor 22.7.10.10.460
2ijmADPFocal adhesion kinase 12.7.10.20.460
2w1fL0FAurora kinase A2.7.11.10.460
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3t113T1Gag-Pol polyprotein3.4.23.160.460
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.460
4gk4L90Ephrin type-A receptor 32.7.10.10.460
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.460
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.460
1bxqPP8Penicillopepsin-13.4.23.200.459
1m2rMNYCasein kinase II subunit alpha2.7.11.10.459
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.459
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.459
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.459
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.459
3ggu017Gag-Pol polyprotein3.4.23.160.459
4bgg844Activin receptor type-12.7.11.300.459
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.459
4grb0XGCasein kinase II subunit alpha2.7.11.10.459
4ix5ANPUncharacterized protein/0.459
4ix6ADPUncharacterized protein/0.459
5dr9SKEAurora kinase A2.7.11.10.459
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.458
2h96893Mitogen-activated protein kinase 82.7.11.240.458
2itqITQEpidermal growth factor receptor2.7.10.10.458
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.458
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.458
3nwxKVSGag-Pol polyprotein3.4.23.160.458
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.458
5auwQUEDeath-associated protein kinase 12.7.11.10.458
1hosPHPGag-Pol polyprotein/0.457
2g226IGRenin3.4.23.150.457
3cgfJNFMitogen-activated protein kinase 102.7.11.240.457
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3igoANPCalmodulin-domain protein kinase 1, putative/0.457
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3oqkS52Renin3.4.23.150.457
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.457
3sw418KCyclin-dependent kinase 22.7.11.220.457
4a6bQG8Gag-Pol polyprotein3.4.23.160.457
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.457
4ivd15TTyrosine-protein kinase JAK1/0.457
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.457
5dnrATPAurora kinase A2.7.11.10.457
1e9hINRCyclin-dependent kinase 22.7.11.220.456
2io6330Wee1-like protein kinase2.7.10.20.456
2qo9ANPEphrin type-A receptor 32.7.10.10.456
2uxpCLMHTH-type transcriptional regulator TtgR/0.456
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.456
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
3eyhIZATyrosine-protein kinase JAK1/0.456
3qxpX64Cyclin-dependent kinase 22.7.11.220.456
3r9hZ67Cyclin-dependent kinase 22.7.11.220.456
4bchT7ZCyclin-dependent kinase 92.7.11.220.456
4btjADPTau-tubulin kinase 12.7.11.10.456
4otiMI1Serine/threonine-protein kinase N1/0.456
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.456
5eg3ACPFibroblast growth factor receptor 2/0.456
1py5PY1TGF-beta receptor type-12.7.11.300.455
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.455
2g20L1ARenin3.4.23.150.455
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.455
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.455
3uhl2NCGag-Pol polyprotein3.4.23.160.455
3w33W19Epidermal growth factor receptor2.7.10.10.455
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.455
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.455
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.455
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.455
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.455
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4ye3G04Gag-Pol polyprotein3.4.23.160.455
5av047XDeath-associated protein kinase 12.7.11.10.455
1m2pHNACasein kinase II subunit alpha2.7.11.10.454
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.454
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.454
1v0oINRCell division control protein 2 homolog2.7.11.220.454
2j0lANPFocal adhesion kinase 12.7.10.20.454
3a8wATPProtein kinase C iota type2.7.11.130.454
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.454
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.454
3ral04ZCyclin-dependent kinase 22.7.11.220.454
3sz0FADSulfide-quinone reductase/0.454
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.454
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4b7xNAPProbable oxidoreductase/0.454
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.454
4iva1J5Tyrosine-protein kinase JAK2/0.454
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.454
4riyADPEpidermal growth factor receptor2.7.10.10.454
1ppm0P1Penicillopepsin-13.4.23.200.453
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.453
2pvlP55Casein kinase II subunit alpha2.7.11.10.453
2pwlACPFibroblast growth factor receptor 2/0.453
3lixE17Protease/0.453
3nwq2NCGag-Pol polyprotein3.4.23.160.453
3own3OWRenin3.4.23.150.453
3pxkPXKFocal adhesion kinase 12.7.10.20.453
4c57FEFCyclin-G-associated kinase2.7.11.10.453
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.453
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.453
4ii5ADPCyclin-dependent kinase 22.7.11.220.453
4j98ACPFibroblast growth factor receptor 2/0.453
4qnyANPMitogen activated protein kinase, putative/0.453
4ux9ANPMitogen-activated protein kinase 82.7.11.240.453
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
5auvAGIDeath-associated protein kinase 12.7.11.10.453
2eufLQQCyclin-dependent kinase 62.7.11.220.452
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.452
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.452
3bqr4RBDeath-associated protein kinase 3/0.452
3ekp478Gag-Pol polyprotein3.4.23.160.452
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.452
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.452
3sw719KCyclin-dependent kinase 22.7.11.220.452
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.452
3w32W32Epidermal growth factor receptor2.7.10.10.452
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.452
5ag6MYAGlycylpeptide N-tetradecanoyltransferase/0.452
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.451
2cchATPCyclin-dependent kinase 22.7.11.220.451
2w4jADPDeath-associated protein kinase 12.7.11.10.451
3gubGUBDeath-associated protein kinase 12.7.11.10.451
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4e4m0NHTyrosine-protein kinase JAK2/0.451
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.451
4hyu1BKMitogen-activated protein kinase 82.7.11.240.451
4ysjADPCalmodulin-like domain protein kinase/0.451
1dssNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.450
2fy5SOPCholine O-acetyltransferase2.3.1.60.450
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.450
2iw84SPCyclin-dependent kinase 22.7.11.220.450
2izsBRQCasein kinase I isoform gamma-32.7.11.10.450
2uzdC85Cyclin-dependent kinase 22.7.11.220.450
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.450
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3mb714ICasein kinase II subunit alpha2.7.11.10.450
3rkb12ZCyclin-dependent kinase 22.7.11.220.450
4bgh3I6Cyclin-dependent kinase 22.7.11.220.450
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4jqeANPCasein kinase II subunit alpha2.7.11.10.450
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.450
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.450
5dr6SKEAurora kinase A2.7.11.10.450
1gii1PUCyclin-dependent kinase 22.7.11.220.449
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1zeoC01Peroxisome proliferator-activated receptor gamma/0.449
2pym1UNGag-Pol polyprotein3.4.23.160.449
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2v7a627Tyrosine-protein kinase ABL12.7.10.20.449
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.449
2x4f16XMyosin light chain kinase family member 42.7.11.10.449
3oqfS51Renin3.4.23.150.449
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.449
4k33ACPFibroblast growth factor receptor 32.7.10.10.449
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
5dpvSKEAurora kinase A2.7.11.10.449
1pxmCK5Cyclin-dependent kinase 22.7.11.220.448
1zrzBI1Protein kinase C iota type2.7.11.130.448
2cciATPCyclin-dependent kinase 22.7.11.220.448
2q5p241Peroxisome proliferator-activated receptor gamma/0.448
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.448
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.448
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.448
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.448
4j97ACPFibroblast growth factor receptor 2/0.448
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.448
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.448
4z34ON7Lysophosphatidic acid receptor 1/0.448
1h1r6CPCyclin-dependent kinase 22.7.11.220.447
2fxdDR7Pol polyprotein/0.447
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.447
3liqE14Protease/0.447
3pe2E1BCasein kinase II subunit alpha2.7.11.10.447
3pqbVGPPutative oxidoreductase/0.447
3slz3TLPutative gag-pro-pol polyprotein/0.447
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.447
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.447
4i22IREEpidermal growth factor receptor2.7.10.10.447
4qnaX11Serine/threonine-protein kinase 242.7.11.10.447
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.447
5cnnANPEpidermal growth factor receptor2.7.10.10.447
1gih1PUCyclin-dependent kinase 22.7.11.220.446
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.446
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
2gjlFMNNitronate monooxygenase1.13.12.160.446
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.446
2pwcG3GGag-Pol polyprotein3.4.23.160.446
2qhcAB1Protease/0.446
3efwAK8Aurora kinase A2.7.11.10.446
3gggNADPrephenate dehydrogenase/0.446
3hziATPSerine/threonine-protein kinase toxin HipA/0.446
3icrCOACoenzyme A disulfide reductase/0.446
3nynSGVG protein-coupled receptor kinase 62.7.11.160.446
3sdi3SDProteasome subunit beta type-53.4.25.10.446
3sdi3SDProteasome subunit beta type-63.4.25.10.446
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.446
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.446
4e5w0NTTyrosine-protein kinase JAK1/0.446
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.446
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.446
4gub0Y4Casein kinase II subunit alpha2.7.11.10.446
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.446
1kkq471Peroxisome proliferator-activated receptor alpha/0.445
2b7zMK1Gag-Pol polyprotein/0.445
2c6iDT1Cyclin-dependent kinase 22.7.11.220.445
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.445
2xb7GUIALK tyrosine kinase receptor2.7.10.10.445
3ad9NADSubunit alpha of sarocosine oxidase/0.445
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.445
3litE15Protease/0.445
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.445
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3oom507Activin receptor type-12.7.11.300.445
3rmf20ZCyclin-dependent kinase 22.7.11.220.445
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.445
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.445
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.445
5l8lADPAurora kinase A2.7.11.10.445
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1oecAA2Fibroblast growth factor receptor 2/0.444
1oiyN41Cyclin-dependent kinase 22.7.11.220.444
2cej1AHPol protein/0.444
2pqzG0GGag-Pol polyprotein3.4.23.160.444
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3gu6ADPDeath-associated protein kinase 12.7.11.10.444
3nc9TR3Ketohexokinase/0.444
3qbfJHGGag-Pol polyprotein3.4.23.160.444
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.444
3zptM8YGag-Pol polyprotein3.4.23.160.444
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.444
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.444
5ap7SVEDual specificity protein kinase TTK2.7.12.10.444
1meiMOAInosine-5'-monophosphate dehydrogenase/0.443
1metDMPGag-Pol polyprotein3.4.23.160.443
1y0s331Peroxisome proliferator-activated receptor delta/0.443
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.443
2i4vDJRV-1 protease/0.443
2pmoHMDProtein kinase 7/0.443
2pvhP19Casein kinase II subunit alpha2.7.11.10.443
3ezvEZVCyclin-dependent kinase 22.7.11.220.443
3kvxFMYMitogen-activated protein kinase 102.7.11.240.443
3qpjN4IGag-Pol polyprotein3.4.23.160.443
3zdu38RCyclin-dependent kinase-like 32.7.11.220.443
4a4qUX9Pol protein/0.443
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4e5yNDPGDP-L-fucose synthase1.1.1.2710.443
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.443
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.443
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.443
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.443
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.443
4gxs0YSGlutamate receptor 2/0.443
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
4wboANWRhodopsin kinase/0.443
4wsqKSAAP2-associated protein kinase 12.7.11.10.443
4xlvACPInsulin receptor2.7.10.10.443
5ax35IDMitogen-activated protein kinase 12.7.11.240.443
5e8wSTUTGF-beta receptor type-12.7.11.300.443
1cdeGARPhosphoribosylglycinamide formyltransferase/0.442
1jkkANPDeath-associated protein kinase 12.7.11.10.442
1k7l544Peroxisome proliferator-activated receptor alpha/0.442
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.442
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.442
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.442
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.442
2qnqQN3Gag-Pol polyprotein3.4.23.160.442
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.442
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.442
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.442
3c4xATPRhodopsin kinase/0.442
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3syiFADSulfide-quinone reductase/0.442
4fko20KCyclin-dependent kinase 22.7.11.220.442
4qmpDKISerine/threonine-protein kinase 242.7.11.10.442
4s34ANPMitogen-activated protein kinase 12.7.11.240.442
1ajvNMBGag-Pol polyprotein3.4.23.160.441
1bil0IURenin3.4.23.150.441
1e3eNAIAlcohol dehydrogenase 41.1.1.10.441
1fmlRTLRetinol dehydratase/0.441
1g35AHFGag-Pol polyprotein3.4.23.160.441
1t7j478Gag-Pol polyprotein3.4.23.160.441
1xl2189Gag-Pol polyprotein3.4.23.160.441
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.441
2c4g514Cyclin-dependent kinase 22.7.11.220.441
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.441
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.441
2q59240Peroxisome proliferator-activated receptor gamma/0.441
2wl05AHGag-Pol polyprotein/0.441
2xru400Aurora kinase A2.7.11.10.441
3a2oKNJGag-Pol polyprotein3.4.23.160.441
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3juhANPCasein kinase II subunit alpha2.7.11.10.441
3livE16Protease/0.441
3mtfA3FActivin receptor type-12.7.11.300.441
3my5RFZCyclin-dependent kinase 22.7.11.220.441
3oxv478Gag-Pol polyprotein3.4.23.160.441
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
4eok4SPCyclin-dependent kinase 22.7.11.220.441
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.441
4lfiGNPCasein kinase II subunit alpha2.7.11.10.441
4uymVOR14-alpha sterol demethylase Cyp51B/0.441
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.441
4z07PCGcGMP-dependent protein kinase 12.7.11.120.441
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.440
1w5vBE3Gag-Pol polyprotein3.4.23.160.440
1xkkFMMEpidermal growth factor receptor2.7.10.10.440
2of2547Tyrosine-protein kinase Lck2.7.10.20.440
2pwrG4GGag-Pol polyprotein3.4.23.160.440
2qd8065Gag-Pol polyprotein3.4.23.160.440
2upjU02Gag-Pol polyprotein3.4.23.160.440
2zdu446Mitogen-activated protein kinase 102.7.11.240.440
3c4zADPRhodopsin kinase/0.440
3l8p0CEAngiopoietin-1 receptor2.7.10.10.440
3nu3478Gag-Pol polyprotein3.4.23.160.440
3q92XNBKetohexokinase/0.440
3rni21ZCyclin-dependent kinase 22.7.11.220.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.440
4b99R4LMitogen-activated protein kinase 72.7.11.240.440
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4dgmAGICasein kinase II subunit alpha2.7.11.10.440
5cshATPCasein kinase II subunit alpha2.7.11.10.440