sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3u8k | 09P | Acetylcholine-binding protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3u8k | 09P | Acetylcholine-binding protein | / | 1.000 | |
| 3u8n | 09S | Acetylcholine-binding protein | / | 0.600 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.578 | |
| 3zdg | XRX | Acetylcholine-binding protein | / | 0.524 | |
| 3wip | ACH | Acetylcholine-binding protein | / | 0.509 | |
| 3u8m | 09R | Acetylcholine-binding protein | / | 0.508 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.503 | |
| 4alx | IZN | Acetylcholine-binding protein | / | 0.502 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.499 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.497 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.496 | |
| 2o12 | FMN | Chorismate synthase | / | 0.495 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.494 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.494 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.493 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.493 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.492 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.492 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.492 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.491 | |
| 1eio | GCH | Gastrotropin | / | 0.490 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.488 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.487 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.486 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.486 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.485 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.485 | |
| 4b5d | SW4 | Achbp | / | 0.485 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.484 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.484 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.483 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.483 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.483 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.483 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.482 | |
| 5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.482 | |
| 2bxm | IMN | Serum albumin | / | 0.481 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.481 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.481 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.480 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.480 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.480 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.480 | |
| 1fml | RTL | Retinol dehydratase | / | 0.479 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.479 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.479 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.479 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.478 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.478 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.477 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.477 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.476 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.476 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.476 | |
| 4afg | QMR | Achbp | / | 0.476 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.475 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.475 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.475 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.474 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.474 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.474 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.473 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.472 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.472 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.472 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.472 | |
| 1osv | CHC | Bile acid receptor | / | 0.471 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.471 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.471 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.471 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.471 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.471 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.471 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.470 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.470 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.470 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.469 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.469 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.469 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.469 | |
| 4pd6 | URI | Nucleoside permease | / | 0.469 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.468 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.468 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.468 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.468 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.468 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.468 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.468 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.468 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.467 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.467 | |
| 1zdw | FLV | Prenyltransferase | / | 0.467 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.467 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.467 | |
| 3zdh | XRS | Acetylcholine-binding protein | / | 0.467 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.466 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.466 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.466 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.466 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.466 | |
| 3b9l | AZZ | Serum albumin | / | 0.466 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.466 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.466 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.466 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.465 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.465 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.465 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.464 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.464 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.464 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.464 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.463 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.463 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.463 | |
| 3iaa | TYD | CalG2 | / | 0.463 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.463 | |
| 4hcy | 0YN | Transketolase | / | 0.463 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 4l4x | NDP | AmphI | / | 0.463 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.463 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.463 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.462 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.462 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.462 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.462 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.462 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.462 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.462 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.462 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.461 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.461 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.461 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.461 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.461 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.461 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.461 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.461 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.461 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.461 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.461 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4v12 | POG | MaoC like domain protein | / | 0.461 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.460 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.460 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.460 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.460 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.460 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.460 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.460 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.460 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.460 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.460 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.460 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.459 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.459 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.459 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 2wb2 | FAD | RE11660p | / | 0.459 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.459 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.459 | |
| 4oae | CLM | Uncharacterized protein | / | 0.459 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.458 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.458 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.458 | |
| 1z7e | UGA | Bifunctional polymyxin resistance protein ArnA | / | 0.458 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.458 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.458 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.458 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.458 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.458 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.457 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.457 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.457 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.457 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.457 | |
| 2wq7 | FAD | RE11660p | / | 0.457 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.457 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.457 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.457 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.456 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.456 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2wq6 | FAD | RE11660p | / | 0.456 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.456 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.456 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.456 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.456 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.456 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.455 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.455 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.455 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.455 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.455 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.455 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.455 | |
| 5a3b | APR | SIR2 family protein | / | 0.455 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.454 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 2e20 | B4P | Propionate kinase | / | 0.454 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.454 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.454 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.454 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.454 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.454 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3p2k | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.454 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.454 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.454 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.454 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.453 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.453 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.453 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.453 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.453 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3n0b | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.453 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.453 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.453 | |
| 4l8u | 9AZ | Serum albumin | / | 0.453 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.452 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.452 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.452 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.452 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.452 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.452 | |
| 4xr9 | NAD | CalS8 | / | 0.452 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.451 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.451 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.451 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.451 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.451 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3vgl | ANP | Glucokinase | / | 0.451 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.451 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.451 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.451 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.450 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.450 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.450 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3e8x | NAP | BH1520 protein | / | 0.450 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.450 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.450 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.449 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.449 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.449 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 2y6q | I7T | TetX family tetracycline inactivation enzyme | / | 0.449 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.449 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.449 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.449 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.449 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.449 | |
| 3up0 | D7S | aceDAF-12 | / | 0.449 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.449 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.449 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.449 | |
| 1gqt | ACP | Ribokinase | / | 0.448 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.448 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.448 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.448 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.448 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.448 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.448 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.448 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.448 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.448 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.448 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.448 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.448 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.448 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.447 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2e07 | SAH | Diphthine synthase | / | 0.447 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.447 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3fst | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.447 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.447 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.447 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.446 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.446 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.446 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.446 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.446 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.446 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4fyh | TR5 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.446 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.446 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.446 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.446 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.446 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.445 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.445 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.445 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.445 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.445 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.445 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.445 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.445 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.445 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.445 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.445 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.445 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.445 | |
| 4hxy | NDP | Plm1 | / | 0.445 | |
| 4jic | FMN | GTN Reductase | / | 0.445 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.445 | |
| 4o4i | GTP | Tubulin alpha-1B chain | / | 0.445 | |
| 4tlz | FAD | KtzI | / | 0.445 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.445 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.444 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.444 | |
| 1mi3 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.444 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.444 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.444 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.444 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4dja | FAD | (6-4) photolyase | / | 0.444 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.443 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.443 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 2q3e | NAI | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.443 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.443 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.443 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.443 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.443 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.443 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.443 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.442 | |
| 1lol | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.442 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.442 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.442 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.442 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.442 | |
| 2owk | SAH | Diphthine synthase | / | 0.442 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.442 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.442 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.442 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.442 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.442 | |
| 4tm0 | FAD | KtzI | / | 0.442 | |
| 5a3c | NAD | SIR2 family protein | / | 0.442 | |
| 5ain | QMR | Soluble acetylcholine receptor | / | 0.442 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.442 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.441 | |
| 1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.441 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1own | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.441 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.441 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.441 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.441 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.441 | |
| 3zuy | TCH | Transporter | / | 0.441 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.441 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.441 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.441 | |
| 4u7w | NDP | MxaA | / | 0.441 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.440 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.440 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.440 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.440 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.440 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.440 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.440 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.440 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.440 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.440 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.440 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.440 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.440 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.440 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.440 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.440 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.440 |