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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3tiz3TICyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3tiz3TICyclin-dependent kinase 22.7.11.221.000
3lfnA27Cyclin-dependent kinase 22.7.11.220.634
3qzhX69Cyclin-dependent kinase 22.7.11.220.619
3unk0BYCyclin-dependent kinase 22.7.11.220.613
3rpv26ZCyclin-dependent kinase 22.7.11.220.608
3r6xX84Cyclin-dependent kinase 22.7.11.220.602
3r7vZ02Cyclin-dependent kinase 22.7.11.220.602
3qxoX65Cyclin-dependent kinase 22.7.11.220.601
4fki09KCyclin-dependent kinase 22.7.11.220.599
3qu0X40Cyclin-dependent kinase 22.7.11.220.595
3qzgX67Cyclin-dependent kinase 22.7.11.220.595
2w1hL0FCyclin-dependent kinase 22.7.11.220.594
4fkq42KCyclin-dependent kinase 22.7.11.220.593
3r8lZ30Cyclin-dependent kinase 22.7.11.220.592
3rm719ZCyclin-dependent kinase 22.7.11.220.591
4fkr45KCyclin-dependent kinase 22.7.11.220.591
3pxyJWSCyclin-dependent kinase 22.7.11.220.585
3qtzX42Cyclin-dependent kinase 22.7.11.220.584
2r3kSCQCyclin-dependent kinase 22.7.11.220.583
3rpo24ZCyclin-dependent kinase 22.7.11.220.583
3r7yZ04Cyclin-dependent kinase 22.7.11.220.580
2c6o4SPCyclin-dependent kinase 22.7.11.220.579
3rm618ZCyclin-dependent kinase 22.7.11.220.579
1ke6LS2Cyclin-dependent kinase 22.7.11.220.577
2w06FRVCyclin-dependent kinase 22.7.11.220.577
3qtuX44Cyclin-dependent kinase 22.7.11.220.577
3rk507ZCyclin-dependent kinase 22.7.11.220.576
3rni21ZCyclin-dependent kinase 22.7.11.220.576
3qwjX6ACyclin-dependent kinase 22.7.11.220.575
3qx2X63Cyclin-dependent kinase 22.7.11.220.575
3r8pZ46Cyclin-dependent kinase 22.7.11.220.575
1di8DTQCyclin-dependent kinase 22.7.11.220.574
1fvt106Cyclin-dependent kinase 22.7.11.220.574
3ddqRRCCyclin-dependent kinase 22.7.11.220.573
3r9dX6BCyclin-dependent kinase 22.7.11.220.573
4acm7YGCyclin-dependent kinase 22.7.11.220.573
3rjc06ZCyclin-dependent kinase 22.7.11.220.572
2a4lRRCCyclin-dependent kinase 22.7.11.220.569
3unj0BXCyclin-dependent kinase 22.7.11.220.569
4fkt48KCyclin-dependent kinase 22.7.11.220.569
3r73X87Cyclin-dependent kinase 22.7.11.220.568
2r3p3SCCyclin-dependent kinase 22.7.11.220.567
3ezvEZVCyclin-dependent kinase 22.7.11.220.567
4ek816KCyclin-dependent kinase 22.7.11.220.566
1ke8LS4Cyclin-dependent kinase 22.7.11.220.564
3qqfX07Cyclin-dependent kinase 22.7.11.220.564
3rak03ZCyclin-dependent kinase 22.7.11.220.563
3ral04ZCyclin-dependent kinase 22.7.11.220.563
3r1sX73Cyclin-dependent kinase 22.7.11.220.562
3s1h56ZCyclin-dependent kinase 22.7.11.220.562
3sw719KCyclin-dependent kinase 22.7.11.220.562
1urwI1PCyclin-dependent kinase 22.7.11.220.561
3iggEFQCyclin-dependent kinase 22.7.11.220.561
1oi9N20Cyclin-dependent kinase 22.7.11.220.560
2r3lSCWCyclin-dependent kinase 22.7.11.220.560
3qtrX36Cyclin-dependent kinase 22.7.11.220.560
3r7iX9ICyclin-dependent kinase 22.7.11.220.558
1ke7LS3Cyclin-dependent kinase 22.7.11.220.557
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.557
3lfsA07Cyclin-dependent kinase 22.7.11.220.557
3roy22ZCyclin-dependent kinase 22.7.11.220.557
1vyzN5BCyclin-dependent kinase 22.7.11.220.556
2a0cCK9Cyclin-dependent kinase 22.7.11.220.556
1v1k3FPCyclin-dependent kinase 22.7.11.220.555
3r1yX76Cyclin-dependent kinase 22.7.11.220.555
1oitHDTCyclin-dependent kinase 22.7.11.220.554
4lyn1YGCyclin-dependent kinase 22.7.11.220.554
3ddpRC8Cyclin-dependent kinase 22.7.11.220.553
1pxmCK5Cyclin-dependent kinase 22.7.11.220.552
1r78FMDCyclin-dependent kinase 22.7.11.220.552
3r7eX88Cyclin-dependent kinase 22.7.11.220.552
3rk708ZCyclin-dependent kinase 22.7.11.220.551
3rmf20ZCyclin-dependent kinase 22.7.11.220.550
1p2a5BNCyclin-dependent kinase 22.7.11.220.549
2btrU73Cyclin-dependent kinase 22.7.11.220.549
1gii1PUCyclin-dependent kinase 22.7.11.220.548
2c5yMTWCyclin-dependent kinase 22.7.11.220.547
2fvdLIACyclin-dependent kinase 22.7.11.220.547
2j9mPY8Cyclin-dependent kinase 22.7.11.220.547
2uzoC62Cyclin-dependent kinase 22.7.11.220.547
3qtxX43Cyclin-dependent kinase 22.7.11.220.547
3rpy27ZCyclin-dependent kinase 22.7.11.220.547
3qqlX03Cyclin-dependent kinase 22.7.11.220.546
3qxpX64Cyclin-dependent kinase 22.7.11.220.546
4fks46KCyclin-dependent kinase 22.7.11.220.546
3qqhX0ACyclin-dependent kinase 22.7.11.220.545
1oiyN41Cyclin-dependent kinase 22.7.11.220.543
4fkj11KCyclin-dependent kinase 22.7.11.220.542
2xmyCDKCyclin-dependent kinase 22.7.11.220.541
4ek610KCyclin-dependent kinase 22.7.11.220.541
4kd11QKCyclin-dependent kinase 22.7.11.220.541
2r64740Cyclin-dependent kinase 22.7.11.220.540
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.540
3r7uX96Cyclin-dependent kinase 22.7.11.220.540
1ckpPVBCyclin-dependent kinase 22.7.11.220.538
3lfqA28Cyclin-dependent kinase 22.7.11.220.538
3sw418KCyclin-dependent kinase 22.7.11.220.538
1pxkCK3Cyclin-dependent kinase 22.7.11.220.537
2b55D31Cyclin-dependent kinase 22.7.11.220.536
4fko20KCyclin-dependent kinase 22.7.11.220.536
3qruX19Cyclin-dependent kinase 22.7.11.220.535
3s0o50ZCyclin-dependent kinase 22.7.11.220.535
2btsU32Cyclin-dependent kinase 22.7.11.220.534
3qziX72Cyclin-dependent kinase 22.7.11.220.534
4bcpT3CCyclin-dependent kinase 22.7.11.220.534
4fkpLS5Cyclin-dependent kinase 22.7.11.220.534
2uznC96Cyclin-dependent kinase 22.7.11.220.533
3ti1B49Cyclin-dependent kinase 22.7.11.220.533
2iw94SPCyclin-dependent kinase 22.7.11.220.532
2r3mSCXCyclin-dependent kinase 22.7.11.220.532
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.532
3qtwX3ACyclin-dependent kinase 22.7.11.220.532
3wblPDYCyclin-dependent kinase 22.7.11.220.532
1ke9LS5Cyclin-dependent kinase 22.7.11.220.531
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.529
2w05FRTCyclin-dependent kinase 22.7.11.220.529
3r1qX75Cyclin-dependent kinase 22.7.11.220.529
3r8vZ62Cyclin-dependent kinase 22.7.11.220.529
3s2pPMUCyclin-dependent kinase 22.7.11.220.529
2b52D42Cyclin-dependent kinase 22.7.11.220.528
1w0xOLOCyclin-dependent kinase 22.7.11.220.526
3ezrEZRCyclin-dependent kinase 22.7.11.220.526
3r28XA0Cyclin-dependent kinase 22.7.11.220.526
4bgh3I6Cyclin-dependent kinase 22.7.11.220.526
3ig7EFPCyclin-dependent kinase 22.7.11.220.525
1h1s4SPCyclin-dependent kinase 22.7.11.220.524
1ke5LS1Cyclin-dependent kinase 22.7.11.220.522
1oguST8Cyclin-dependent kinase 22.7.11.220.521
4fkv61KCyclin-dependent kinase 22.7.11.220.520
1oiuN76Cyclin-dependent kinase 22.7.11.220.519
3sqq99ZCyclin-dependent kinase 22.7.11.220.519
3fz1B98Cyclin-dependent kinase 22.7.11.220.517
2iw84SPCyclin-dependent kinase 22.7.11.220.516
3r9hZ67Cyclin-dependent kinase 22.7.11.220.516
4bcnT9NCyclin-dependent kinase 22.7.11.220.516
1h1r6CPCyclin-dependent kinase 22.7.11.220.515
3pj8404Cyclin-dependent kinase 22.7.11.220.515
2r3jSCJCyclin-dependent kinase 22.7.11.220.514
1g5sI17Cyclin-dependent kinase 22.7.11.220.513
1pxlCK4Cyclin-dependent kinase 22.7.11.220.513
2vu3LZECyclin-dependent kinase 22.7.11.220.513
3py0SU9Cyclin-dependent kinase 22.7.11.220.513
3rkb12ZCyclin-dependent kinase 22.7.11.220.513
4eor4SPCyclin-dependent kinase 22.7.11.220.513
1oiqHDUCyclin-dependent kinase 22.7.11.220.512
3ql8X01Cyclin-dependent kinase 22.7.11.220.512
2vv9IM9Cyclin-dependent kinase 22.7.11.220.511
3r71X86Cyclin-dependent kinase 22.7.11.220.511
3raiX85Cyclin-dependent kinase 22.7.11.220.511
1pxpCK8Cyclin-dependent kinase 22.7.11.220.509
1ykr628Cyclin-dependent kinase 22.7.11.220.507
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.507
3qx4X4BCyclin-dependent kinase 22.7.11.220.507
3rahO1ZCyclin-dependent kinase 22.7.11.220.505
3rzb02ZCyclin-dependent kinase 22.7.11.220.505
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.505
2c6iDT1Cyclin-dependent kinase 22.7.11.220.504
3qqkX02Cyclin-dependent kinase 22.7.11.220.504
3r83Z14Cyclin-dependent kinase 22.7.11.220.504
4eol1ROCyclin-dependent kinase 22.7.11.220.504
4ez30S0Cyclin-dependent kinase 22.7.11.220.503
2uzlC94Cyclin-dependent kinase 22.7.11.220.502
3my5RFZCyclin-dependent kinase 22.7.11.220.502
3qzfX66Cyclin-dependent kinase 22.7.11.220.502
3r9nZ68Cyclin-dependent kinase 22.7.11.220.502
2vttLZDCyclin-dependent kinase 22.7.11.220.501
1w8cN69Cyclin-dependent kinase 22.7.11.220.500
2r3r6SCCyclin-dependent kinase 22.7.11.220.500
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.499
4erwSTUCyclin-dependent kinase 22.7.11.220.499
4fx360KCyclin-dependent kinase 22.7.11.220.499
1e9hINRCyclin-dependent kinase 22.7.11.220.498
2b54D05Cyclin-dependent kinase 22.7.11.220.498
4fkw62KCyclin-dependent kinase 22.7.11.220.498
1vyw292Cyclin-dependent kinase 22.7.11.220.496
3sheI85MAP kinase-activated protein kinase 32.7.11.10.496
3le62BZCyclin-dependent kinase 22.7.11.220.495
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.494
2x1nX1NCyclin-dependent kinase 22.7.11.220.494
3r8zZ63Cyclin-dependent kinase 22.7.11.220.493
3qtsX46Cyclin-dependent kinase 22.7.11.220.492
1h1pCMGCyclin-dependent kinase 22.7.11.220.491
1pyePM1Cyclin-dependent kinase 22.7.11.220.491
2r3iSCFCyclin-dependent kinase 22.7.11.220.491
3s00Z60Cyclin-dependent kinase 22.7.11.220.491
3nga3NGCasein kinase II subunit alpha2.7.11.10.490
1gih1PUCyclin-dependent kinase 22.7.11.220.489
2duv371Cyclin-dependent kinase 22.7.11.220.489
3r9oZ71Cyclin-dependent kinase 22.7.11.220.489
1aq1STUCyclin-dependent kinase 22.7.11.220.488
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.488
4bcoT6QCyclin-dependent kinase 22.7.11.220.488
4eok4SPCyclin-dependent kinase 22.7.11.220.488
3dogNNNCyclin-dependent kinase 22.7.11.220.487
3qqgX06Cyclin-dependent kinase 22.7.11.220.487
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.487
1oirHDYCyclin-dependent kinase 22.7.11.220.486
2vthLZ2Cyclin-dependent kinase 22.7.11.220.486
4eon1ROCyclin-dependent kinase 22.7.11.220.486
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.485
3qrtX14Cyclin-dependent kinase 22.7.11.220.485
3qtqX35Cyclin-dependent kinase 22.7.11.220.484
2r3gSC9Cyclin-dependent kinase 22.7.11.220.483
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.483
4fkg4CKCyclin-dependent kinase 22.7.11.220.483
2c69CT8Cyclin-dependent kinase 22.7.11.220.482
2r3o2SCCyclin-dependent kinase 22.7.11.220.482
2wxvWXVCyclin-dependent kinase 22.7.11.220.482
2zdt46CMitogen-activated protein kinase 102.7.11.240.482
3rk909ZCyclin-dependent kinase 22.7.11.220.482
2bhhRYUCyclin-dependent kinase 22.7.11.220.481
2c4g514Cyclin-dependent kinase 22.7.11.220.481
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.481
2w17I19Cyclin-dependent kinase 22.7.11.220.481
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.480
2r3fSC8Cyclin-dependent kinase 22.7.11.220.480
2cchATPCyclin-dependent kinase 22.7.11.220.479
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.479
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.479
1h0w207Cyclin-dependent kinase 22.7.11.220.478
3be9P04Casein kinase II subunit alpha2.7.11.10.478
3qwkX62Cyclin-dependent kinase 22.7.11.220.478
3rpr25ZCyclin-dependent kinase 22.7.11.220.478
1unlRRCCyclin-dependent-like kinase 52.7.11.10.477
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.477
4c4jX21Dual specificity protein kinase TTK2.7.12.10.477
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.477
5dr6SKEAurora kinase A2.7.11.10.477
2b53D23Cyclin-dependent kinase 22.7.11.220.476
3oqfS51Renin3.4.23.150.476
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.475
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.475
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.475
2vtsLZCCyclin-dependent kinase 22.7.11.220.474
4tuvCPZCytochrome P450 1191.140.474
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.473
4cfnJYMCyclin-dependent kinase 22.7.11.220.473
1gij2PUCyclin-dependent kinase 22.7.11.220.472
1y8yCT7Cyclin-dependent kinase 22.7.11.220.472
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.472
1pkdUCNCyclin-dependent kinase 22.7.11.220.471
2pvnP63Casein kinase II subunit alpha2.7.11.10.471
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.471
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.471
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.471
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.470
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.470
1eh4IC1Casein kinase I homolog 12.7.11.10.469
1xjdSTUProtein kinase C theta type2.7.11.130.469
2wpa889Cyclin-dependent kinase 22.7.11.220.469
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.469
3hz5Z64Heat shock protein HSP 90-alpha/0.469
3r8uZ31Cyclin-dependent kinase 22.7.11.220.469
4au8Z3RCyclin-dependent-like kinase 52.7.11.10.469
1h1q2A6Cyclin-dependent kinase 22.7.11.220.468
2pmoHMDProtein kinase 7/0.468
2r3q5SCCyclin-dependent kinase 22.7.11.220.468
2xikJ60Serine/threonine-protein kinase 252.7.11.10.468
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.468
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.468
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.468
1pxoCK7Cyclin-dependent kinase 22.7.11.220.467
3uli1N3Cyclin-dependent kinase 22.7.11.220.467
1uydPU8Heat shock protein HSP 90-alpha/0.466
2zjwREFCasein kinase II subunit alpha2.7.11.10.466
4eos1ROCyclin-dependent kinase 22.7.11.220.466
2uxoTACHTH-type transcriptional regulator TtgR/0.465
3f47I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.465
4bcmT7ZCyclin-dependent kinase 22.7.11.220.465
4gk4L90Ephrin type-A receptor 32.7.10.10.465
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.465
2vtqLZACyclin-dependent kinase 22.7.11.220.464
2wipP49Cyclin-dependent kinase 22.7.11.220.464
4eop1ROCyclin-dependent kinase 22.7.11.220.464
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.464
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.463
2uzeC95Cyclin-dependent kinase 22.7.11.220.463
3dmtNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.463
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.463
3tnwF18Cyclin-dependent kinase 22.7.11.220.463
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.463
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.463
4fv8E63Mitogen-activated protein kinase 12.7.11.240.463
4l8u9AZSerum albumin/0.463
1xddAAYIntegrin alpha-L/0.462
2uzbC75Cyclin-dependent kinase 22.7.11.220.462
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.462
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.462
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.462
4btjADPTau-tubulin kinase 12.7.11.10.462
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.462
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.462
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.462
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.462
1x1bSAHC-20 methyltransferase/0.461
2b7aIZATyrosine-protein kinase JAK2/0.461
2bheBRYCyclin-dependent kinase 22.7.11.220.461
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.461
3tucFPWTyrosine-protein kinase SYK2.7.10.20.461
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.461
4jlj1NMDeoxycytidine kinase2.7.1.740.461
2i40BLZCyclin-dependent kinase 22.7.11.220.460
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.460
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.460
4aua4AUCyclin-dependent kinase 62.7.11.220.460
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.460
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.460
4qmpDKISerine/threonine-protein kinase 242.7.11.10.460
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.460
1fvv107Cyclin-dependent kinase 22.7.11.220.459
2c68CT6Cyclin-dependent kinase 22.7.11.220.459
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.459
3ttjJBIMitogen-activated protein kinase 102.7.11.240.459
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.459
4a6bQG8Gag-Pol polyprotein3.4.23.160.459
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.459
4wboANWRhodopsin kinase/0.459
2excJNKMitogen-activated protein kinase 102.7.11.240.458
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.458
3qlsNDPDihydrofolate reductase1.5.1.30.458
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.458
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.458
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.458
2c6kDT2Cyclin-dependent kinase 22.7.11.220.457
2c6tDT5Cyclin-dependent kinase 22.7.11.220.457
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.457
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.457
3ggfGVDSerine/threonine-protein kinase 26/0.457
3zh8C58Protein kinase C iota type2.7.11.130.457
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.457
5a3bAPRSIR2 family protein/0.457
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.456
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.456
2o0uC0MMitogen-activated protein kinase 102.7.11.240.456
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.456
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.456
3r3sNADPutative oxidoreductase/0.456
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.456
4eoi1ROCyclin-dependent kinase 22.7.11.220.456
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.456
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.456
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.456
1osvCHCBile acid receptor/0.455
2c6lDT4Cyclin-dependent kinase 22.7.11.220.455
2pvlP55Casein kinase II subunit alpha2.7.11.10.455
2qo9ANPEphrin type-A receptor 32.7.10.10.455
2wotZZGTGF-beta receptor type-12.7.11.300.455
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.455
4gk2L66Ephrin type-A receptor 32.7.10.10.455
4i22IREEpidermal growth factor receptor2.7.10.10.455
1om1IQACasein kinase II subunit alpha2.7.11.10.454
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.454
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.454
2vnaNAPProstaglandin reductase 21.3.1.480.454
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.454
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.454
3at4CCKCasein kinase II subunit alpha2.7.11.10.454
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.454
4dgnLU2Casein kinase II subunit alpha2.7.11.10.454
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
2c5nCK8Cyclin-dependent kinase 22.7.11.220.453
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.453
2ebaFADPutative glutaryl-CoA dehydrogenase/0.453
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.453
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
2xnbY8LCyclin-dependent kinase 22.7.11.220.453
4g2fC07Ephrin type-A receptor 32.7.10.10.453
4jk3NADUncharacterized protein/0.453
4kb81QNCasein kinase I isoform delta2.7.11.10.453
5cu6ATPCasein kinase II subunit alpha2.7.11.10.453
1ie8KH1Vitamin D3 receptor/0.452
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.452
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.452
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.452
4fv9E71Mitogen-activated protein kinase 12.7.11.240.452
1e1xNW1Cyclin-dependent kinase 22.7.11.220.451
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1phgMYTCamphor 5-monooxygenase1.14.15.10.451
1ruoCMPcAMP-activated global transcriptional regulator CRP/0.451
1ungALHCyclin-dependent-like kinase 52.7.11.10.451
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.451
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.451
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.451
2xa4AZ5Tyrosine-protein kinase JAK2/0.451
3d8vUD1Bifunctional protein GlmU/0.451
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.451
3nx4NAPPutative oxidoreductase/0.451
3poz03PEpidermal growth factor receptor2.7.10.10.451
1v0pPVBCell division control protein 2 homolog2.7.11.220.450
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.450
2csnCKICasein kinase I homolog 12.7.11.10.450
2vwpNDPGlucose 1-dehydrogenase/0.450
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3mdmFJZCholesterol 24-hydroxylase/0.450
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.450
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.450
4ryvZEAProtein LlR18A/0.450
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1kzjCB3Thymidylate synthase/0.449
1npa3NHGag-Pol polyprotein3.4.23.160.449
1npvL27Gag-Pol polyprotein3.4.23.160.449
1npwLGZGag-Pol polyprotein3.4.23.160.449
1uyePU9Heat shock protein HSP 90-alpha/0.449
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.449
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.449
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.449
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3qn8NI7Gag-Pol polyprotein3.4.23.160.449
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.449
3t2kFADSulfide-quinone reductase/0.449
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
3wxyCOAUncharacterized protein/0.449
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.449
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4o1mNADEnoyl-acyl carrier reductase/0.449
4qmzB49Serine/threonine-protein kinase 242.7.11.10.449
1h0vUN4Cyclin-dependent kinase 22.7.11.220.448
1hiv1ZKGag-Pol polyprotein/0.448
1y4lSVRBasic phospholipase A2 homolog 2/0.448
2c6mDT5Cyclin-dependent kinase 22.7.11.220.448
2h96893Mitogen-activated protein kinase 82.7.11.240.448
2nq8ZIDEnoyl-ACP reductase/0.448
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.448
3bhy7CPDeath-associated protein kinase 3/0.448
3bqr4RBDeath-associated protein kinase 3/0.448
3l8p0CEAngiopoietin-1 receptor2.7.10.10.448
4b1uLABActin, alpha skeletal muscle/0.448
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4dpwAGSMevalonate diphosphate decarboxylase/0.448
4e730NRMitogen-activated protein kinase 82.7.11.240.448
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.447
2cig1DGDihydrofolate reductase1.5.1.30.447
2f2cAP9Cyclin-dependent kinase 62.7.11.220.447
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.447
2r43G3GGag-Pol polyprotein3.4.23.160.447
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.447
2x9dITCTetracycline repressor protein class D/0.447
2xngA0HAurora kinase A2.7.11.10.447
3s54017Protease/0.447
3sz0FADSulfide-quinone reductase/0.447
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.447
3zep1NXTyrosine-protein kinase JAK32.7.10.20.447
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.447
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.447
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.447
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.447
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.447
1u3cFADCryptochrome-1/0.446
1uyfPU1Heat shock protein HSP 90-alpha/0.446
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.446
2vtrLZBCyclin-dependent kinase 22.7.11.220.446
2xzwATPNitrogen regulatory protein P-II/0.446
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.446
3gxlQIGTGF-beta receptor type-12.7.11.300.446
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.446
3oom507Activin receptor type-12.7.11.300.446
1ajxAH1Gag-Pol polyprotein3.4.23.160.445
1cqp803Integrin alpha-L/0.445
1nzdUPGDNA beta-glucosyltransferase/0.445
1ouy094Mitogen-activated protein kinase 14/0.445
1pg3PRXAcetyl-coenzyme A synthetase/0.445
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.445
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.445
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.445
3axwTIDCasein kinase II subunit alpha2.7.11.10.445
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3f1kNAPUncharacterized oxidoreductase YciK10.445
3hx4ANPCalmodulin-domain protein kinase 1/0.445
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3mvl38PMitogen-activated protein kinase 14/0.445
3uxyNADShort-chain dehydrogenase/reductase SDR/0.445
3zsi52PMitogen-activated protein kinase 14/0.445
4aqc88ATyrosine-protein kinase JAK2/0.445
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.445
4nb6444Nuclear receptor ROR-gamma/0.445
4o8aFADBifunctional protein PutA1.2.1.880.445
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.445
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.444
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2hog710Serine/threonine-protein kinase Chk12.7.11.10.444
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.444
2lbaCHOFatty acid binding protein 6/0.444
2vf0F89Thymidylate synthase/0.444
2y6o1N1Ephrin type-A receptor 42.7.10.10.444
3aidARQGag-Pol polyprotein3.4.23.160.444
3h65I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.444
3ha5SFGHydroxymycolate synthase MmaA42.1.10.444
3u4uLNHCasein kinase II subunit alpha2.7.11.10.444
3zewSTUEphrin type-B receptor 42.7.10.10.444
3zy3GDPGDP-fucose protein O-fucosyltransferase 12.4.1.2210.444
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.444
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.444
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.444
4qmySTUSerine/threonine-protein kinase 242.7.11.10.444
4wsqKSAAP2-associated protein kinase 12.7.11.10.444
1i5aACPChemotaxis protein CheA2.7.13.30.443
1ijjLARActin, alpha skeletal muscle/0.443
1odw0E8Gag-Pol polyprotein3.4.23.160.443
1wlvCOAPhenylacetic acid degradation protein PaaI/0.443
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.443
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.443
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3i60E86Mitogen-activated protein kinase 12.7.11.240.443
3mdvCL6Cholesterol 24-hydroxylase/0.443
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.443
4ivb1J5Tyrosine-protein kinase JAK1/0.443
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.443
1jld0PPGag-Pol polyprotein/0.442
1me6IVSPlasmepsin-23.4.23.390.442
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.442
1tlcF89Thymidylate synthase/0.442
1v9aSAHUncharacterized protein/0.442
2dvlFADAcyl-CoA dehydrogenase/0.442
2jkkBI9Focal adhesion kinase 12.7.10.20.442
2q7vFADThioredoxin reductase/0.442
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.442
3at3ATKCasein kinase II subunit alpha2.7.11.10.442
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.442
3cgfJNFMitogen-activated protein kinase 102.7.11.240.442
3gubGUBDeath-associated protein kinase 12.7.11.10.442
3k5uPFQAurora kinase A2.7.11.10.442
3lqfNADGalactitol dehydrogenase/0.442
3q9yTXQCasein kinase II subunit alpha2.7.11.10.442
3w33W19Epidermal growth factor receptor2.7.10.10.442
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.442
4gmy0X5Tyrosine-protein kinase JAK2/0.442
4jsfQJ4Nitric oxide synthase, brain1.14.13.390.442
4l9kEHFSerum albumin/0.442
4mwhATPCasein kinase II subunit alpha2.7.11.10.442
5upjUINGag-Pol polyprotein/0.442
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.441
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1w2xRCPAcetyl-CoA carboxylase/0.441
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.441
2c3qGTXGlutathione S-transferase theta-12.5.1.180.441
2of2547Tyrosine-protein kinase Lck2.7.10.20.441
2p33J07Mitogen-activated protein kinase 102.7.11.240.441
2xb7GUIALK tyrosine kinase receptor2.7.10.10.441
3dokGWJPol protein/0.441
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.441
3h9f92MDual specificity protein kinase TTK2.7.12.10.441
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.441
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.441
3rvg17PTyrosine-protein kinase JAK2/0.441
4c02TAKActivin receptor type-12.7.11.300.441
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.441
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4uymVOR14-alpha sterol demethylase Cyp51B/0.441
1dm2HMDCyclin-dependent kinase 22.7.11.220.440
1tj0FADBifunctional protein PutA1.5.5.20.440
1ysx4EBSerum albumin/0.440
2bx8AZQSerum albumin/0.440
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
2dv5SAHDiphthine synthase/0.440
2hveADPNucleoside diphosphate kinase A2.7.4.60.440
2p4yC03Peroxisome proliferator-activated receptor gamma/0.440
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.440
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
3ggoNAIPrephenate dehydrogenase/0.440
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.440
3qp0NI8Gag-Pol polyprotein3.4.23.160.440
3t1tGDPProbable gliding protein mglA/0.440
4a6cQG9Gag-Pol polyprotein3.4.23.160.440
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4nu5NADPhosphonate dehydrogenase1.20.1.10.440
4nu6NADPhosphonate dehydrogenase1.20.1.10.440
4q71FADBifunctional protein PutA/0.440
5e8xSTUTGF-beta receptor type-12.7.11.300.440
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.440
4z34ON7Lysophosphatidic acid receptor 1/0.440
3qakUKAAdenosine receptor A2a/0.440