scPDB - Distribution of Binding site Similarity values of 3fyw entry / Site 1

PDB ID	HET	Uniprot Name	EC Number
3fyw	XCF	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3fyw	XCF	Dihydrofolate reductase	1.5.1.3	1.000
3frd	DHF	Dihydrofolate reductase	1.5.1.3	0.747
3fre	TOP	Dihydrofolate reductase	1.5.1.3	0.714
3fy9	XCF	Dihydrofolate reductase	1.5.1.3	0.667
3fy8	XCF	Dihydrofolate reductase	1.5.1.3	0.650
3fyv	XCF	Dihydrofolate reductase	1.5.1.3	0.650
3frf	XCF	Dihydrofolate reductase	1.5.1.3	0.645
3fra	I2H	Dihydrofolate reductase	1.5.1.3	0.637
4xe6	06U	Dihydrofolate reductase	1.5.1.3	0.633
3srq	Q19	Dihydrofolate reductase	1.5.1.3	0.605
3sh2	5DR	Dihydrofolate reductase	1.5.1.3	0.601
3jw5	TOP	Dihydrofolate reductase	/	0.600
2w3v	TOP	Dihydrofolate reductase	/	0.597
3sa1	6DR	Dihydrofolate reductase	/	0.594
4fgh	0U6	Dihydrofolate reductase	1.5.1.3	0.587
1rx3	MTX	Dihydrofolate reductase	1.5.1.3	0.583
3jwc	EKB	Dihydrofolate reductase	/	0.583
3sru	Q26	Dihydrofolate reductase	1.5.1.3	0.583
3m08	RAR	Dihydrofolate reductase	1.5.1.3	0.580
3cse	N22	Uncharacterized protein	/	0.579
3ia4	MTX	Dihydrofolate reductase	/	0.579
3srw	Q27	Dihydrofolate reductase	1.5.1.3	0.579
1klk	PMD	Dihydrofolate reductase	1.5.1.3	0.578
2w9g	TOP	Dihydrofolate reductase	1.5.1.3	0.575
3jwm	5WB	Dihydrofolate reductase	/	0.570
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.569
4elg	52J	Dihydrofolate reductase	/	0.568
1m7a	MQU	Dihydrofolate reductase	1.5.1.3	0.567
3srr	Q20	Dihydrofolate reductase	1.5.1.3	0.567
3td8	D2R	Dihydrofolate reductase	1.5.1.3	0.567
1dg5	TOP	Dihydrofolate reductase	1.5.1.3	0.565
3eel	53T	Uncharacterized protein	/	0.565
3sai	9DR	Dihydrofolate reductase	/	0.565
4nx6	FOL	Dihydrofolate reductase	1.5.1.3	0.565
3eej	53R	Uncharacterized protein	/	0.561
3qlz	QLZ	Uncharacterized protein	/	0.560
3tqb	FOL	Dihydrofolate reductase	/	0.559
4ele	31I	Dihydrofolate reductase	/	0.559
3inv	C50	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.556
4elb	34S	Dihydrofolate reductase	/	0.554
1daj	MOT	Dihydrofolate reductase	1.5.1.3	0.553
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.553
3qls	55V	Dihydrofolate reductase	1.5.1.3	0.553
2zza	FOL	Dihydrofolate reductase	/	0.550
3qlx	QLR	Uncharacterized protein	/	0.550
3kjs	DQ1	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.549
3dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.548
4h98	14Q	Uncharacterized protein	/	0.548
1cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.546
4h96	14Q	Dihydrofolate reductase	1.5.1.3	0.546
3iro	2CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.545
3jw3	TOP	Dihydrofolate reductase	/	0.544
1df7	MTX	Dihydrofolate reductase	1.5.1.3	0.543
4m2x	TMQ	Dihydrofolate reductase	1.5.1.3	0.543
3qlw	N22	Dihydrofolate reductase	1.5.1.3	0.542
3qlr	QLR	Dihydrofolate reductase	1.5.1.3	0.541
3dga	RJ1	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.540
3sa2	7DR	Dihydrofolate reductase	/	0.540
3eek	53S	Uncharacterized protein	/	0.539
3tq9	MTX	Dihydrofolate reductase	/	0.539
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.538
3qly	55V	Uncharacterized protein	/	0.538
3dat	MTX	Dihydrofolate reductase	/	0.537
3sgy	06W	Dihydrofolate reductase	1.5.1.3	0.537
4nx7	FOL	Dihydrofolate reductase	1.5.1.3	0.537
2fzh	DH1	Dihydrofolate reductase	1.5.1.3	0.535
2qk8	MTX	Dihydrofolate reductase	/	0.534
3srs	M23	Dihydrofolate reductase	1.5.1.3	0.534
3fl8	RAR	Dihydrofolate reductase	/	0.532
1qzf	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.529
2fzi	DH3	Dihydrofolate reductase	1.5.1.3	0.528
3jsu	KA5	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.528
1ly3	COG	Dihydrofolate reductase	1.5.1.3	0.527
3eem	53V	Uncharacterized protein	/	0.527
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.527
4elh	53I	Dihydrofolate reductase	/	0.525
4ixe	IXE	Dihydrofolate reductase	1.5.1.3	0.524
1dg7	WRB	Dihydrofolate reductase	1.5.1.3	0.522
3ix9	MTX	Dihydrofolate reductase	1.5.1.3	0.518
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.518
3cd2	MTX	Dihydrofolate reductase	1.5.1.3	0.517
4ixf	IXF	Dihydrofolate reductase	1.5.1.3	0.516
4elf	35I	Dihydrofolate reductase	/	0.514
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.512
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.512
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.510
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.510
1j3k	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.508
1aoe	GW3	Dihydrofolate reductase	1.5.1.3	0.507
4p66	MTX	Dihydrofolate reductase	/	0.507
1j3i	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.506
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.506
4elb	34R	Dihydrofolate reductase	/	0.506
3fl9	TOP	Dihydrofolate reductase	/	0.504
4kjj	FOL	Dihydrofolate reductase	1.5.1.3	0.503
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.502
3dau	MTX	Dihydrofolate reductase	1.5.1.3	0.502
3tq8	TOP	Dihydrofolate reductase	/	0.502
4x5f	FOL	Dihydrofolate reductase	1.5.1.3	0.501
4h97	53S	Dihydrofolate reductase	1.5.1.3	0.500
2har	OCC	Vitamin D3 receptor	/	0.498
2cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.497
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.494
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.493
4fhh	0U3	Vitamin D3 receptor A	/	0.493
4dp3	MMV	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.492
4x5g	FOL	Dihydrofolate reductase	1.5.1.3	0.492
3um5	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.491
4ia3	BIV	Vitamin D3 receptor A	/	0.491
2y6f	M9F	Isopenicillin N synthase	1.21.3.1	0.490
4ia7	BIV	Vitamin D3 receptor A	/	0.490
4ixg	IXG	Dihydrofolate reductase	1.5.1.3	0.490
4lcg	1WM	UDP-3-O-acyl-N-acetylglucosamine deacetylase	/	0.490
1dis	BDM	Dihydrofolate reductase	1.5.1.3	0.489
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.489
1ly4	COQ	Dihydrofolate reductase	1.5.1.3	0.489
3m09	RAR	Dihydrofolate reductase	1.5.1.3	0.489
4fgg	0U5	Dihydrofolate reductase	1.5.1.3	0.489
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.487
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.487
3d80	Q22	Dihydrofolate reductase	1.5.1.3	0.487
3qfx	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.487
3zbn	COA	3-ketoacyl-CoA thiolase-like protein	/	0.487
4nky	3QZ	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.487
1guf	NDP	Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial	1.3.1.10	0.486
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.485
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.485
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.485
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.484
2y1o	T26	UDP-N-acetylmuramoylalanine--D-glutamate ligase	6.3.2.9	0.484
2hb7	O1C	Vitamin D3 receptor	/	0.483
4fhi	0S4	Vitamin D3 receptor A	/	0.483
4g8z	TOP	Dihydrofolate reductase	1.5.1.3	0.483
3gc9	B45	Mitogen-activated protein kinase 11	2.7.11.24	0.482
4j6d	TES	Cytochrome P450 monooxygenase	/	0.482
2hcd	BIV	Vitamin D3 receptor A	/	0.481
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.480
2o4j	VD4	Vitamin D3 receptor	/	0.480
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.480
4hgt	15G	Casein kinase I isoform delta	2.7.11.1	0.480
1dyr	TOP	Dihydrofolate reductase	1.5.1.3	0.479
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.479
1s0z	EB1	Vitamin D3 receptor	/	0.478
2has	C3O	Vitamin D3 receptor	/	0.478
4ite	TEY	Vitamin D3 receptor	/	0.478
4nb6	444	Nuclear receptor ROR-gamma	/	0.478
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.477
2hb8	MVD	Vitamin D3 receptor	/	0.477
3vt5	YI2	Vitamin D3 receptor	/	0.477
1m13	HYF	Nuclear receptor subfamily 1 group I member 2	/	0.476
3a78	3EV	Vitamin D3 receptor	/	0.476
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.476
3kpz	ZNE	Vitamin D3 receptor	/	0.476
3um6	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.476
1ie9	VDX	Vitamin D3 receptor	/	0.475
1kzj	CB3	Thymidylate synthase	/	0.475
3anl	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.475
4ia1	BIV	Vitamin D3 receptor A	/	0.475
1db1	VDX	Vitamin D3 receptor	/	0.474
2hbh	XE4	Vitamin D3 receptor A	/	0.474
3zsi	52P	Mitogen-activated protein kinase 14	/	0.474
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.474
2ham	C33	Vitamin D3 receptor	/	0.473
3mdv	CL6	Cholesterol 24-hydroxylase	/	0.473
3qgt	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.473
4i3w	NAD	Aldehyde dehydrogenase (NAD+)	/	0.473
4j6c	STR	Cytochrome P450 monooxygenase	/	0.473
1qiq	ACC	Isopenicillin N synthase	1.21.3.1	0.472
3vt9	YI4	Vitamin D3 receptor	/	0.472
1rkh	VD2	Vitamin D3 receptor	/	0.471
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.471
3a1l	2CC	Cytochrome P450	/	0.471
3nga	3NG	Casein kinase II subunit alpha	2.7.11.1	0.471
4g2i	0VQ	Vitamin D3 receptor	/	0.471
1rk3	VDX	Vitamin D3 receptor	/	0.470
2bl9	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.470
2vn0	TDZ	Cytochrome P450 2C8	/	0.470
4ia2	BIV	Vitamin D3 receptor A	/	0.470
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.469
1rx2	FOL	Dihydrofolate reductase	1.5.1.3	0.469
1s19	MC9	Vitamin D3 receptor	/	0.469
2zla	VDB	Vitamin D3 receptor	/	0.469
3fco	IIG	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.469
4ezj	0SC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.469
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.468
2o4r	VD5	Vitamin D3 receptor	/	0.468
1ouy	094	Mitogen-activated protein kinase 14	/	0.467
1rjk	VDZ	Vitamin D3 receptor	/	0.467
3lfc	Z86	Mitogen-activated protein kinase 14	/	0.467
3lu8	IQX	Serum albumin	/	0.467
3vt8	YI3	Vitamin D3 receptor	/	0.467
1qxo	FMN	Chorismate synthase	/	0.466
2pzi	AXX	Serine/threonine-protein kinase PknG	2.7.11.1	0.466
2yki	YKI	Heat shock protein HSP 90-alpha	/	0.466
3ctj	320	Hepatocyte growth factor receptor	2.7.10.1	0.466
3vrv	YSD	Vitamin D3 receptor	/	0.466
3vrw	YS5	Vitamin D3 receptor	/	0.466
4ge4	0KE	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.466
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.466
1ie8	KH1	Vitamin D3 receptor	/	0.465
1txi	TX5	Vitamin D3 receptor	/	0.465
1uy7	PU4	Heat shock protein HSP 90-alpha	/	0.465
2hc4	VDX	Vitamin D3 receptor A	/	0.465
2hw2	RFP	Rifampin ADP-ribosyl transferase	/	0.465
2jko	BIJ	Focal adhesion kinase 1	2.7.10.2	0.465
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.465
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.465
3irx	UDR	Gag-Pol polyprotein	2.7.7.49	0.465
3qaq	QAQ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.465
3r3f	4CO	4-hydroxybenzoyl-CoA thioesterase	3.1.2.23	0.465
3w0r	ANP	Hygromycin-B 4-O-kinase	2.7.1.163	0.465
1rkg	VD1	Vitamin D3 receptor	/	0.464
2i4z	DRH	Peroxisome proliferator-activated receptor gamma	/	0.464
2jkq	VG8	Focal adhesion kinase 1	2.7.10.2	0.464
3cgc	COA	Coenzyme A disulfide reductase	/	0.464
3cv9	VDX	Vitamin D3 dihydroxylase	/	0.464
3d0b	SNX	Heat shock protein HSP 90-alpha	/	0.464
3l8s	BFF	Mitogen-activated protein kinase 14	/	0.464
3mdm	FJZ	Cholesterol 24-hydroxylase	/	0.464
3vt7	VDX	Vitamin D3 receptor	/	0.464
3vtc	TK3	Vitamin D3 receptor	/	0.464
4g1d	0VK	Vitamin D3 receptor A	/	0.464
4g1y	0VO	Vitamin D3 receptor A	/	0.464
4g21	0VP	Vitamin D3 receptor A	/	0.464
1a72	PAD	Alcohol dehydrogenase E chain	1.1.1.1	0.463
3imx	B84	Glucokinase	2.7.1.2	0.463
3w0a	DS5	Vitamin D3 receptor	/	0.463
4awi	AQ2	Mitogen-activated protein kinase 8	2.7.11.24	0.463
5hi6	MTX	Dihydrofolate reductase	/	0.463
1rt4	UC1	Gag-Pol polyprotein	2.7.7.49	0.462
4b7s	QLE	Cytochrome P450 monooxygenase PikC	/	0.462
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.462
2jfa	RAL	Estrogen receptor	/	0.461
2pmd	GNP	Translation initiation factor 2 subunit gamma	/	0.461
2q9f	C3S	Cholesterol 24-hydroxylase	/	0.461
3i0r	RT3	Gag-Pol polyprotein	2.7.7.49	0.461
3icr	COA	Coenzyme A disulfide reductase	/	0.461
3wd7	COA	Acridone synthase	/	0.461
3zux	TCH	Transporter	/	0.461
4h8n	NDP	NADPH-dependent conjugated polyketone reductase C2	/	0.461
4l9k	EHF	Serum albumin	/	0.461
4nkv	AER	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.461
1okz	UCN	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.460
1uy8	PU5	Heat shock protein HSP 90-alpha	/	0.460
2p33	J07	Mitogen-activated protein kinase 10	2.7.11.24	0.460
3czr	3CZ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.460
3fwj	CAM	Camphor 5-monooxygenase	1.14.15.1	0.460
3gkj	HC3	Niemann-Pick C1 protein	/	0.460
3hz1	37D	Heat shock protein HSP 90-alpha	/	0.460
3mee	T27	Gag-Pol polyprotein	2.7.7.49	0.460
3qm4	PN0	Cytochrome P450 2D6	/	0.460
3vt3	VDX	Vitamin D3 receptor	/	0.460
4jq7	KJQ	Epidermal growth factor receptor	2.7.10.1	0.460
4l8u	9AZ	Serum albumin	/	0.460
4v12	POG	MaoC like domain protein	/	0.460
1s4d	SAH	Uroporphyrinogen-III C-methyltransferase	2.1.1.107	0.459
1suo	CPZ	Cytochrome P450 2B4	1.14.14.1	0.459
1uho	VDN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.459
2cig	1DG	Dihydrofolate reductase	1.5.1.3	0.459
2p1u	4TN	Retinoic acid receptor RXR-alpha	/	0.459
2vg7	NNI	Gag-Pol polyprotein	2.7.7.49	0.459
2zlc	VDX	Vitamin D3 receptor	/	0.459
3cgf	JNF	Mitogen-activated protein kinase 10	2.7.11.24	0.459
3gwf	FAD	Cyclohexanone monooxygenase	/	0.459
3ncg	BK1	Calmodulin-domain protein kinase 1, putative	/	0.459
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.459
4anq	VGH	ALK tyrosine kinase receptor	2.7.10.1	0.459
4o70	1QK	Bromodomain-containing protein 4	/	0.459
1dz6	CAM	Camphor 5-monooxygenase	1.14.15.1	0.458
1kbo	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.458
1zeo	C01	Peroxisome proliferator-activated receptor gamma	/	0.458
2c59	NAD	GDP-mannose 3,5-epimerase	5.1.3.18	0.458
2ovy	PFJ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.458
2wue	KEK	4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase	3.7.1.17	0.458
3ibq	ATP	Pyridoxal kinase	/	0.458
3qf9	NM8	Serine/threonine-protein kinase pim-1	2.7.11.1	0.458
3r04	UNQ	Serine/threonine-protein kinase pim-1	2.7.11.1	0.458
3ruk	AER	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.458
4ezk	0SD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.458
4o71	CPB	Bromodomain-containing protein 4	/	0.458
4wa9	AXI	Tyrosine-protein kinase ABL1	2.7.10.2	0.458
5awm	ANP	Stress-activated protein kinase JNK	2.7.11.24	0.458
1iyz	NDP	Probable quinone oxidoreductase	/	0.457
1v7a	FRC	Adenosine deaminase	3.5.4.4	0.457
2qbn	CAM	Camphor 5-monooxygenase	1.14.15.1	0.457
3ofm	4B0	Casein kinase II subunit alpha'	2.7.11.1	0.457
3qwb	NDP	Probable quinone oxidoreductase	1.6.5.5	0.457
3r0t	FU9	Casein kinase II subunit alpha	2.7.11.1	0.457
3tda	PN0	Cytochrome P450 2D6	/	0.457
4ajw	VWN	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	2.7.1.153	0.457
4cuk	NAI	D-lactate dehydrogenase	/	0.457
4fjy	FJY	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.457
4ubs	DIF	Pentalenic acid synthase	1.14.15.11	0.457
4yr9	NAD	L-threonine 3-dehydrogenase, mitochondrial	1.1.1.103	0.457
1e7v	LY2	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.456
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.456
1uzw	CDH	Isopenicillin N synthase	1.21.3.1	0.456
2bbq	PFG	Thymidylate synthase	/	0.456
2y30	SM8	Putative repressor SimReg2	/	0.456
3inx	JZC	Heat shock protein HSP 90-alpha	/	0.456
3m7r	VDX	Vitamin D3 receptor	/	0.456
3nr4	PYV	Abscisic acid receptor PYL2	/	0.456
3qlh	T27	Gag-Pol polyprotein	2.7.7.49	0.456
3vru	YS3	Vitamin D3 receptor	/	0.456
3vtb	TKA	Vitamin D3 receptor	/	0.456
4b7d	QLE	Cytochrome P450 monooxygenase PikC	/	0.456
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.456
4xum	IMN	Peroxisome proliferator-activated receptor gamma	/	0.456
5c03	AGS	Non-receptor tyrosine-protein kinase TYK2	2.7.10.2	0.456
1rfv	ADP	Pyridoxal kinase	2.7.1.35	0.455
1uy9	PU6	Heat shock protein HSP 90-alpha	/	0.455
2chw	039	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
2h55	DZ8	Heat shock protein HSP 90-alpha	/	0.455
2nnh	REA	Cytochrome P450 2C8	/	0.455
2qbl	CAM	Camphor 5-monooxygenase	1.14.15.1	0.455
2wug	HPK	4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase	3.7.1.17	0.455
2yei	XQI	Heat shock protein HSP 90-alpha	/	0.455
3apf	BMW	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
3gxo	MQA	Mitomycin biosynthesis 6-O-methyltransferase	/	0.455
3i8a	N22	Dihydrofolate reductase	1.5.1.3	0.455
3meg	T27	Gag-Pol polyprotein	2.7.7.49	0.455
3nsz	ANP	Casein kinase II subunit alpha	2.7.11.1	0.455
3oom	507	Activin receptor type-1	2.7.11.30	0.455
3opd	HIE	Heat shock protein 83	/	0.455
3sr5	Q12	Dihydrofolate reductase	1.5.1.3	0.455
3ssn	MVI	Mycinamicin VI 2''-O-methyltransferase	/	0.455
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.455
4i7f	NVE	Gag-Pol polyprotein	2.7.7.49	0.455
4itf	TFY	Vitamin D3 receptor	/	0.455
4j6b	PLO	Cytochrome P450 monooxygenase	/	0.455
4jqe	ANP	Casein kinase II subunit alpha	2.7.11.1	0.455
5eyp	LOC	Tubulin beta chain	/	0.455
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.454
1cbo	FAD	Cholesterol oxidase	1.1.3.6	0.454
1ep4	S11	Gag-Pol polyprotein	2.7.7.49	0.454
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.454
1rg7	MTX	Dihydrofolate reductase	1.5.1.3	0.454
1uyf	PU1	Heat shock protein HSP 90-alpha	/	0.454
2blc	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.454
2fto	CB3	Thymidylate synthase	/	0.454
2h96	893	Mitogen-activated protein kinase 8	2.7.11.24	0.454
2m56	CAM	Camphor 5-monooxygenase	1.14.15.1	0.454
2vqo	TFG	Histone deacetylase 4	3.5.1.98	0.454
2y60	M8F	Isopenicillin N synthase	1.21.3.1	0.454
3bej	MUF	Bile acid receptor	/	0.454
3bgq	VX2	Serine/threonine-protein kinase pim-1	2.7.11.1	0.454
3irn	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.454
3sgv	2BJ	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.454
3w0y	DS4	Vitamin D3 receptor	/	0.454
4c58	824	Cyclin-G-associated kinase	2.7.11.1	0.454
4eft	EFT	Heat shock protein HSP 90-alpha	/	0.454
4jlc	SU6	Serine/threonine-protein kinase TBK1	2.7.11.1	0.454
4tuv	CPZ	Cytochrome P450 119	1.14	0.454
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.454
1aj8	COA	Citrate synthase	/	0.453
1cbq	RE9	Cellular retinoic acid-binding protein 2	/	0.453
1r9o	FLP	Cytochrome P450 2C9	/	0.453
1uyd	PU8	Heat shock protein HSP 90-alpha	/	0.453
2qbo	CAM	Camphor 5-monooxygenase	1.14.15.1	0.453
3bv2	P38	Mitogen-activated protein kinase 14	/	0.453
3caq	NDP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.453
3dei	RXB	Caspase-3	3.4.22.56	0.453
3ds6	A17	Mitogen-activated protein kinase 14	/	0.453
3ln1	CEL	Prostaglandin G/H synthase 2	1.14.99.1	0.453
3mvl	38P	Mitogen-activated protein kinase 14	/	0.453
3ns2	PYV	Abscisic acid receptor PYL2	/	0.453
3w0c	6DS	Vitamin D3 receptor	/	0.453
4bgi	I4I	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.453
4c9p	CAM	Cytochrome P450	/	0.453
4g1z	0VP	Vitamin D3 receptor A	/	0.453
4j0r	1H2	Bromodomain-containing protein 4	/	0.453
4jlk	1NO	Deoxycytidine kinase	2.7.1.74	0.453
4xsr	UPG	Alr3699 protein	/	0.453
5e8x	STU	TGF-beta receptor type-1	2.7.11.30	0.453
1uy6	PU3	Heat shock protein HSP 90-alpha	/	0.452
2d8a	NAD	L-threonine 3-dehydrogenase	/	0.452
2fwz	H71	Heat shock protein HSP 90-alpha	/	0.452
2i4p	DRH	Peroxisome proliferator-activated receptor gamma	/	0.452
3c7q	XIN	Vascular endothelial growth factor receptor 2	2.7.10.1	0.452
3cbs	R12	Cellular retinoic acid-binding protein 2	/	0.452
3dej	RXC	Caspase-3	3.4.22.56	0.452
3ml8	ML8	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.452
3nj0	PYV	Abscisic acid receptor PYL2	/	0.452
3pe2	E1B	Casein kinase II subunit alpha	2.7.11.1	0.452
4aot	GW8	Serine/threonine-protein kinase 10	2.7.11.1	0.452
4b8z	NAP	GDP-L-fucose synthase	1.1.1.271	0.452
4dre	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.452
4fsr	HKC	Serine/threonine-protein kinase Chk1	2.7.11.1	0.452
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.452
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.452
1pp9	SMA	Cytochrome b	/	0.451
1qkn	RAL	Estrogen receptor beta	/	0.451
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.451
2hk9	NAP	Shikimate dehydrogenase (NADP(+))	/	0.451
2ihv	TPP	N(2)-(2-carboxyethyl)arginine synthase	/	0.451
2vxo	XMP	GMP synthase [glutamine-hydrolyzing]	6.3.5.2	0.451
2x9d	ITC	Tetracycline repressor protein class D	/	0.451
2y5s	78H	Dihydropteroate synthase	/	0.451
3el7	PD3	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.451
3fls	FLS	Mitogen-activated protein kinase 14	/	0.451
3nwy	GTP	Uridylate kinase	/	0.451
3nx4	NAP	Putative oxidoreductase	/	0.451
3pe6	ZYH	Monoglyceride lipase	/	0.451
3w5t	LHP	Vitamin D3 receptor	/	0.451
4bqg	50Q	Heat shock protein HSP 90-alpha	/	0.451
4cp4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.451
4i2p	G73	Gag-Pol polyprotein	2.7.7.49	0.451
4jnm	1LJ	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.451
4ly9	1YY	Glucokinase regulatory protein	/	0.451
4mq1	2C3	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	2.7.12.1	0.451
4rr8	A3S	Probable threonine--tRNA ligase 2	6.1.1.3	0.451
4v2g	ITC	Tetracycline repressor protein class D	/	0.451
5itz	LOC	Tubulin beta-2B chain	/	0.451
3eml	ZMA	Adenosine receptor A2a	/	0.451
1boz	PRD	Dihydrofolate reductase	1.5.1.3	0.450
1ju6	LYA	Thymidylate synthase	2.1.1.45	0.450
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.450
1uyk	PUX	Heat shock protein HSP 90-alpha	/	0.450
2b0m	201	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.450
2ewa	SB2	Mitogen-activated protein kinase 14	/	0.450
2exc	JNK	Mitogen-activated protein kinase 10	2.7.11.24	0.450
2wi7	2KL	Heat shock protein HSP 90-alpha	/	0.450
2wkm	PFY	Hepatocyte growth factor receptor	2.7.10.1	0.450
2zl9	VDA	Vitamin D3 receptor	/	0.450
4dym	IYZ	Activin receptor type-1	2.7.11.30	0.450
4e73	0NR	Mitogen-activated protein kinase 8	2.7.11.24	0.450
4eil	CB3	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.450
4fex	0TO	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.450
4g3r	CAM	Camphor 5-monooxygenase	1.14.15.1	0.450
4nxv	GDP	Mitochondrial dynamics protein MID51	/	0.450
1cjk	FOK	Adenylate cyclase type 2	/	0.449
1cjk	FOK	Adenylate cyclase type 5	/	0.449
1g4s	TPS	Thiamine-phosphate synthase	/	0.449
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.449
1t88	CAM	Camphor 5-monooxygenase	1.14.15.1	0.449
1wc1	TAT	Adenylate cyclase	/	0.449
1yqj	6NP	Mitogen-activated protein kinase 14	/	0.449
1yrd	CAM	Camphor 5-monooxygenase	1.14.15.1	0.449
2c0o	L2G	Tyrosine-protein kinase HCK	2.7.10.2	0.449
2c3q	GTX	Glutathione S-transferase theta-1	2.5.1.18	0.449
2fb8	215	Serine/threonine-protein kinase B-raf	2.7.11.1	0.449
2idz	ZID	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.449
2rio	ADP	Serine/threonine-protein kinase/endoribonuclease IRE1	2.7.11.1	0.449
2ybo	SAH	Methyltransferase	/	0.449
2zyn	BCD	Periplasmic binding protein	/	0.449
3ft8	MOJ	Heat shock protein HSP 90-alpha	/	0.449
3hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.449
3t8v	BTJ	M1 family aminopeptidase	3.4.11	0.449
3vev	0H4	Glucokinase	2.7.1.2	0.449
3w0i	O11	Vitamin D3 receptor	/	0.449
3w0q	ANP	Hygromycin-B 4-O-kinase	2.7.1.163	0.449
4acd	GR9	Glycogen synthase kinase-3 beta	2.7.11.26	0.449
4f1s	F1S	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.449
4jq8	KJ8	Epidermal growth factor receptor	2.7.10.1	0.449
4jvb	1M0	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	/	0.449
4jvf	17X	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	/	0.449
4rqv	ATP	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.449
4ruo	BIV	Vitamin D3 receptor A	/	0.449
4xiv	ACP	Chemotaxis protein CheA	2.7.13.3	0.449
4xiv	ADP	Chemotaxis protein CheA	2.7.13.3	0.449
4ysw	NAI	Xanthine dehydrogenase/oxidase	/	0.449
4k5y	1Q5	Corticotropin-releasing factor receptor 1	/	0.449
1bk0	ACV	Isopenicillin N synthase	1.21.3.1	0.448
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.448
1dz4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.448
1j3j	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.448
1lhw	ESM	Sex hormone-binding globulin	/	0.448
1szm	BI4	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.448
1uye	PU9	Heat shock protein HSP 90-alpha	/	0.448
1w83	L11	Mitogen-activated protein kinase 14	/	0.448
1yhs	STU	Serine/threonine-protein kinase pim-1	2.7.11.1	0.448
1zrz	BI1	Protein kinase C iota type	2.7.11.13	0.448
2c3i	IYZ	Serine/threonine-protein kinase pim-1	2.7.11.1	0.448
2cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.448
2fwy	H64	Heat shock protein HSP 90-alpha	/	0.448
2kce	D16	Thymidylate synthase	/	0.448
2vkd	UPG	Cytotoxin L	/	0.448
3a99	ANP	Serine/threonine-protein kinase pim-1	2.7.11.1	0.448
3i4b	Z48	Glycogen synthase kinase-3 beta	2.7.11.26	0.448
3w0j	T08	Vitamin D3 receptor	/	0.448
3zvu	A8S	Abscisic acid receptor PYR1	/	0.448
4eiy	ZMA	Adenosine receptor A2a	/	0.448
4h3y	SAH	tRNA (guanine-N(1)-)-methyltransferase	/	0.448
4izy	1J2	Mitogen-activated protein kinase 8	2.7.11.24	0.448
4ku5	DCC	3-oxoacyl-[ACP] synthase III	/	0.448
4rrx	LUR	Prostaglandin G/H synthase 2	1.14.99.1	0.448
6cp4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.448
1hqu	HBY	Gag-Pol polyprotein	2.7.7.49	0.447
1hvy	D16	Thymidylate synthase	2.1.1.45	0.447
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.447
1kce	CB3	Thymidylate synthase	/	0.447
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.447
1ohk	COP	Dihydrofolate reductase	1.5.1.3	0.447
1phg	MYT	Camphor 5-monooxygenase	1.14.15.1	0.447
1qjf	ACS	Isopenicillin N synthase	1.21.3.1	0.447
1upb	TPP	N(2)-(2-carboxyethyl)arginine synthase	/	0.447
1zhz	ERG	Oxysterol-binding protein homolog 4	/	0.447
2bdf	24A	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.447
2g78	REA	Cellular retinoic acid-binding protein 2	/	0.447
2oiq	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.447
2wou	ZZF	TGF-beta receptor type-1	2.7.11.30	0.447
2ykj	YKJ	Heat shock protein HSP 90-alpha	/	0.447
3atz	FMN	Prostaglandin F2a synthase	/	0.447
3d7k	D7K	Benzaldehyde lyase	/	0.447
3f69	XDR	Serine/threonine-protein kinase PknB	2.7.11.1	0.447
3h3s	H15	Collagen type IV alpha-3-binding protein	/	0.447
3pjc	PJC	Tyrosine-protein kinase JAK3	2.7.10.2	0.447
3q9x	EMO	Casein kinase II subunit alpha	2.7.11.1	0.447
3qlg	1N1	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.447
3rwp	ABQ	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.447
3ua5	06X	Cytochrome P450 2B6	1.14.13	0.447
3zsg	T75	Mitogen-activated protein kinase 14	/	0.447
4bqp	VMY	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.447
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.447
4j0s	1H3	Bromodomain-containing protein 4	/	0.447
4l3j	5FI	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.447
4xwr	FAD	Cholesterol oxidase	1.1.3.6	0.447
4xxg	FAD	Cholesterol oxidase	1.1.3.6	0.447
3rfm	CFF	Adenosine receptor A2a	/	0.447
1bif	AGS	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4	2.7.1.105	0.446
1k6t	XN1	Gag-Pol polyprotein	3.4.23.16	0.446
1lco	PPY	Cytochrome b2, mitochondrial	1.1.2.3	0.446
1sd1	FMC	S-methyl-5'-thioadenosine phosphorylase	/	0.446
1xqc	AEJ	Estrogen receptor	/	0.446
1yi3	LY2	Serine/threonine-protein kinase pim-1	2.7.11.1	0.446
2p2h	994	Vascular endothelial growth factor receptor 2	2.7.10.1	0.446
2wuf	KEM	4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase	3.7.1.17	0.446
2yej	ZZ3	Heat shock protein HSP 90-alpha	/	0.446
2zaw	CAM	Camphor 5-monooxygenase	1.14.15.1	0.446
3hu1	AGS	Transitional endoplasmic reticulum ATPase	3.6.4.6	0.446
3ibd	CPZ	Cytochrome P450 2B6	1.14.13	0.446
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.446
3tm5	SFG	Uncharacterized protein	/	0.446
3up3	XCA	aceDAF-12	/	0.446
3uwl	FOZ	Thymidylate synthase	/	0.446
3w0h	W12	Vitamin D3 receptor	/	0.446
4dpu	AGS	Mevalonate diphosphate decarboxylase	/	0.446
4g1q	T27	Gag-Pol polyprotein	2.7.7.49	0.446
4g2h	0VQ	Vitamin D3 receptor A	/	0.446
4hhd	FMN	Phototropin-1	2.7.11.1	0.446
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.446
4nk9	2K5	Fibroblast growth factor receptor 1	/	0.446
4oal	245	Cytokinin dehydrogenase 4	/	0.446
4qpm	ADP	Mitotic checkpoint serine/threonine-protein kinase BUB1	2.7.11.1	0.446
4r20	AER	Cytochrome P450 family 17 polypeptide 2	/	0.446
4xgi	NAD	Glutamate dehydrogenase	/	0.446
4yuq	KS1	Calmodulin-like domain protein kinase	/	0.446
5k2a	ZMA	Adenosine receptor A2a	/	0.446
1ao8	MTX	Dihydrofolate reductase	1.5.1.3	0.445
1cul	FOK	Adenylate cyclase type 2	/	0.445
1cul	FOK	Adenylate cyclase type 5	/	0.445
1f12	3HC	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.445
1og5	SWF	Cytochrome P450 2C9	/	0.445
1q97	ATP	Serine/threonine-protein kinase SKY1	2.7.11.1	0.445
1rt5	UC2	Gag-Pol polyprotein	2.7.7.49	0.445
1tl1	H18	Gag-Pol polyprotein	2.7.7.49	0.445
1v0p	PVB	Cell division control protein 2 homolog	2.7.11.22	0.445
1wlv	COA	Phenylacetic acid degradation protein PaaI	/	0.445
1zg3	2HI	Isoflavone 4'-O-methyltransferase	/	0.445
2etr	Y27	Rho-associated protein kinase 1	2.7.11.1	0.445
2uxu	NAR	HTH-type transcriptional regulator TtgR	/	0.445
2vnh	FAD	NADPH:ferredoxin reductase	/	0.445
2y98	MIV	Mycinamicin IV hydroxylase/epoxidase	/	0.445
2yej	XQK	Heat shock protein HSP 90-alpha	/	0.445
2ykb	YKB	Heat shock protein HSP 90-alpha	/	0.445
3a4o	STU	Tyrosine-protein kinase Lyn	2.7.10.2	0.445
3be9	P04	Casein kinase II subunit alpha	2.7.11.1	0.445
3bfb	9OD	Pheromone-binding protein ASP1	/	0.445
3qlf	PD5	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.445
3s79	ASD	Aromatase	1.14.14.14	0.445
3ttj	JBI	Mitogen-activated protein kinase 10	2.7.11.24	0.445
3vs5	VSG	Tyrosine-protein kinase HCK	2.7.10.2	0.445
3vt6	5YI	Vitamin D3 receptor	/	0.445
4b5p	ACO	Alpha-tubulin N-acetyltransferase 1	/	0.445
4eev	L1X	Hepatocyte growth factor receptor	2.7.10.1	0.445
4egn	TWO	Cytochrome P450	/	0.445
4ffl	ADP	Uncharacterized protein	/	0.445
4gxs	0YS	Glutamate receptor 2	/	0.445
4h6p	FMN	Chromate reductase	/	0.445
4hnc	0UT	Mandelate racemase	/	0.445
4wbo	ANW	Rhodopsin kinase	/	0.445
4yzc	STU	Serine/threonine-protein kinase/endoribonuclease IRE1	2.7.11.1	0.445
5fm7	ADP	RuvB-like helicase	/	0.445
1fvt	106	Cyclin-dependent kinase 2	2.7.11.22	0.444
1ijh	FAD	Cholesterol oxidase	1.1.3.6	0.444
1n4h	REA	Nuclear receptor ROR-beta	/	0.444
1r6g	442	Thyroid hormone receptor beta	/	0.444
1ykd	CMP	Adenylate cyclase	/	0.444
2a1n	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
2aqi	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.444
2iwu	NP5	ATP-dependent molecular chaperone HSP82	/	0.444
2q61	SF1	Peroxisome proliferator-activated receptor gamma	/	0.444
2z97	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
2zax	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
3cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
3ggg	NAD	Prephenate dehydrogenase	/	0.444
3h1j	SMA	Cytochrome b	/	0.444
3hz5	Z64	Heat shock protein HSP 90-alpha	/	0.444
3jpv	1DR	Serine/threonine-protein kinase pim-1	2.7.11.1	0.444
3oq1	3OQ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.444
3t3q	9PL	Cytochrome P450 2A6	1.14.13	0.444
3vt4	5YI	Vitamin D3 receptor	/	0.444
3x0a	5GP	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	2.7.1.149	0.444
4ez8	DHF	Thymidylate synthase	2.1.1.45	0.444
4gg5	0J3	Hepatocyte growth factor receptor	2.7.10.1	0.444
4j7x	SAS	Sepiapterin reductase	1.1.1.153	0.444
4k2x	FAD	Polyketide oxygenase/hydroxylase	/	0.444
4mxx	DB8	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.444
4uyg	73B	Bromodomain-containing protein 2	/	0.444
5dc5	B3N	Histone deacetylase 8	3.5.1.98	0.444
5im3	DTP	Ribonucleoside-diphosphate reductase	/	0.444
1buc	FAD	Acyl-CoA dehydrogenase, short-chain specific	1.3.8.1	0.443
1byg	STU	Tyrosine-protein kinase CSK	/	0.443
1fwm	CB3	Thymidylate synthase	/	0.443
1ppj	ANY	Cytochrome b	/	0.443
1q5d	EPB	Epothilone C/D epoxidase	1.14	0.443
1sej	F89	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.443
1zid	ZID	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.443
2blb	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.443
2iod	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.443
2oax	SNL	Mineralocorticoid receptor	/	0.443
2q59	240	Peroxisome proliferator-activated receptor gamma	/	0.443
2w9h	TOP	Dihydrofolate reductase	1.5.1.3	0.443
2xvi	FAD	Putative flavin-containing monooxygenase	/	0.443
3a0i	AJI	Glucokinase	2.7.1.2	0.443
3ce3	1FN	Hepatocyte growth factor receptor	2.7.10.1	0.443
3cqu	CQU	RAC-alpha serine/threonine-protein kinase	2.7.11.1	0.443
3u4u	LNH	Casein kinase II subunit alpha	2.7.11.1	0.443
3vrt	YS2	Vitamin D3 receptor	/	0.443
3w0g	W07	Vitamin D3 receptor	/	0.443
3zc3	NAP	Ferredoxin--NADP reductase	1.18.1.2	0.443
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.443
4gk2	L66	Ephrin type-A receptor 3	2.7.10.1	0.443
4k0y	1OA	Serine/threonine-protein kinase pim-1	2.7.11.1	0.443
4o4f	ATP	Kinase	/	0.443
1bh5	GTX	Lactoylglutathione lyase	4.4.1.5	0.442
1fdu	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.442
1lsj	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.442
1noo	CAH	Camphor 5-monooxygenase	1.14.15.1	0.442
1rye	NDP	Glucose--fructose oxidoreductase	1.1.99.28	0.442
1sn0	T44	Transthyretin	/	0.442
1sn5	T3	Transthyretin	/	0.442
1yw2	PGJ	Mitogen-activated protein kinase 14	/	0.442
1zyj	BI5	Mitogen-activated protein kinase 14	/	0.442
2hl0	A3S	Threonine--tRNA ligase	6.1.1.3	0.442
2ivu	ZD6	Proto-oncogene tyrosine-protein kinase receptor Ret	2.7.10.1	0.442
2nmt	NHM	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.442
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.442
2x4f	16X	Myosin light chain kinase family member 4	2.7.11.1	0.442
2yaa	ATP	Death-associated protein kinase 2	/	0.442
2z3u	CRR	Cytochrome P450	/	0.442
3ad9	NAD	Subunit alpha of sarocosine oxidase	/	0.442
3ada	NAD	Subunit alpha of sarocosine oxidase	/	0.442
3be2	RAJ	Vascular endothelial growth factor receptor 2	2.7.10.1	0.442
3hll	I45	Mitogen-activated protein kinase 14	/	0.442
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.442
3o0g	3O0	Cyclin-dependent-like kinase 5	2.7.11.1	0.442
3qpv	ADP	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	2.7.1.105	0.442
3t2k	FAD	Sulfide-quinone reductase	/	0.442
3tea	4CO	4-hydroxybenzoyl-CoA thioesterase	3.1.2.23	0.442
3uk6	ADP	RuvB-like 2	3.6.4.12	0.442
3v3m	0EN	Replicase polyprotein 1a	3.4.19.12	0.442
3v9v	21L	Peroxisome proliferator-activated receptor gamma	/	0.442
3zk5	Z18	Cytochrome P450 monooxygenase PikC	/	0.442
4awo	99B	Heat shock protein HSP 90-alpha	/	0.442
4fk3	325	Serine/threonine-protein kinase B-raf	2.7.11.1	0.442
4g1w	G1W	Mitogen-activated protein kinase 8	2.7.11.24	0.442
4g3e	0WC	Mitogen-activated protein kinase kinase kinase 14	2.7.11.25	0.442
4hyu	1BK	Mitogen-activated protein kinase 8	2.7.11.24	0.442
4ipw	1G7	Mycocyclosin synthase	1.14.21.9	0.442
4kao	KAO	Focal adhesion kinase 1	2.7.10.2	0.442
4l2y	XXK	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	/	0.442
4l4d	CAM	Camphor 5-monooxygenase	1.14.15.1	0.442
4neu	Q1A	Receptor-interacting serine/threonine-protein kinase 1	2.7.11.1	0.442
4nka	2K7	Fibroblast growth factor receptor 1	/	0.442
4nmb	FAD	Bifunctional protein PutA	/	0.442
4p6x	HCY	Glucocorticoid receptor	/	0.442
4wlo	NAI	Malate dehydrogenase, mitochondrial	1.1.1.37	0.442
1cqp	803	Integrin alpha-L	/	0.441
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.441
1f4f	TP3	Thymidylate synthase	/	0.441
1fm7	DFV	Chalcone--flavonone isomerase 1	5.5.1.6	0.441
1fml	RTL	Retinol dehydratase	/	0.441
1gld	ADP	Glycerol kinase	/	0.441
1y0s	331	Peroxisome proliferator-activated receptor delta	/	0.441
2bxe	1FL	Serum albumin	/	0.441
2dwp	ACP	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	2.7.1.105	0.441
2i4j	DRJ	Peroxisome proliferator-activated receptor gamma	/	0.441
2of4	979	Tyrosine-protein kinase Lck	2.7.10.2	0.441
2rhr	EMO	Putative ketoacyl reductase	1.3.1	0.441
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.441
2vx0	7X7	Ephrin type-B receptor 4	2.7.10.1	0.441
2xgs	44P	Uncharacterized protein	/	0.441
3cbl	STU	Tyrosine-protein kinase Fes/Fps	2.7.10.2	0.441
3dho	B2M	Streptogramin A acetyltransferase	2.3.1	0.441
3h1v	TK1	Glucokinase	2.7.1.2	0.441
3hdm	MMG	Serine/threonine-protein kinase Sgk1	2.7.11.1	0.441
3l08	ZIG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441
3m8q	DJZ	Gag-Pol polyprotein	2.7.7.49	0.441
3p99	LNP	Lanosterol 14-alpha-demethylase	/	0.441
3tmz	06X	Cytochrome P450 2B4	1.14.14.1	0.441
3zhr	TPP	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.441
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.441
4bch	T7Z	Cyclin-dependent kinase 9	2.7.11.22	0.441
4bw1	S5B	Bromodomain-containing protein 4	/	0.441
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.441
4dca	ADP	Aminoglycoside phosphotransferase	/	0.441
4euf	NAD	Trans-2-enoyl-CoA reductase [NADH]	/	0.441
4ezl	0SE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441
4fjz	4FJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441
4hni	16W	Casein kinase I isoform epsilon	2.7.11.1	0.441
4ivw	1GJ	Estrogen receptor	/	0.441
4jr3	KJR	Epidermal growth factor receptor	2.7.10.1	0.441
4ktc	1X3	Genome polyprotein	3.4.21.98	0.441
4lmu	QUE	Serine/threonine-protein kinase pim-1	2.7.11.1	0.441
4mcv	29K	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.441
4y12	AGS	Serine/threonine-protein kinase PknG	2.7.11.1	0.441
4zp1	TPP	Pyruvate decarboxylase	4.1.1.1	0.441
5cu6	ATP	Casein kinase II subunit alpha	2.7.11.1	0.441
1bws	NDP	GDP-L-fucose synthase	/	0.440
1eet	BFU	Gag-Pol polyprotein	2.7.7.49	0.440
1kgj	FL8	Transthyretin	/	0.440
1kl2	FON	Serine hydroxymethyltransferase	/	0.440
1m2r	MNY	Casein kinase II subunit alpha	2.7.11.1	0.440
1nq1	4HY	Thyroid hormone receptor beta	/	0.440
1osv	CHC	Bile acid receptor	/	0.440
1s14	NOV	DNA topoisomerase 4 subunit B	/	0.440
1t86	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440
1tkt	H12	Gag-Pol polyprotein	2.7.7.49	0.440
1upa	TPP	N(2)-(2-carboxyethyl)arginine synthase	/	0.440
1yi4	ADN	Serine/threonine-protein kinase pim-1	2.7.11.1	0.440
2f4j	VX6	Tyrosine-protein kinase ABL1	2.7.10.2	0.440
2ojg	19A	Mitogen-activated protein kinase 1	2.7.11.24	0.440
2p7z	OHT	Estrogen-related receptor gamma	/	0.440
2qg2	A91	Heat shock protein HSP 90-alpha	/	0.440
2zva	1N1	Tyrosine-protein kinase Lyn	2.7.10.2	0.440
3cs8	BRL	Peroxisome proliferator-activated receptor gamma	/	0.440
3e5a	VX6	Aurora kinase A	2.7.11.1	0.440
3fi3	JK2	Mitogen-activated protein kinase 10	2.7.11.24	0.440
3l6j	Z90	Alr2278 protein	/	0.440
3r6p	A8S	Abscisic acid receptor PYL10	/	0.440
3stx	BKA	Methylketone synthase I	/	0.440
3ubd	SL0	Ribosomal protein S6 kinase alpha-3	2.7.11.1	0.440
3w1f	1O5	Dual specificity protein kinase TTK	2.7.12.1	0.440
4dgn	LU2	Casein kinase II subunit alpha	2.7.11.1	0.440
4dqu	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.440
4fr4	STU	Serine/threonine-protein kinase 32A	2.7.11.1	0.440
4gki	0JN	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.440
4gue	QCT	Ribosomal protein S6 kinase alpha-3	2.7.11.1	0.440
4k1b	1OC	Serine/threonine-protein kinase pim-1	2.7.11.1	0.440
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.440
4nks	2M2	Fibroblast growth factor receptor 1	/	0.440
4qa1	B3N	Histone deacetylase 8	3.5.1.98	0.440
4qi9	MTX	Dihydrofolate reductase	/	0.440
4rrh	A3S	Probable threonine--tRNA ligase 2	6.1.1.3	0.440
4ruj	VDX	Vitamin D3 receptor A	/	0.440
5dr2	ATP	Aurora kinase A	2.7.11.1	0.440
5ej4	TD6	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	/	0.440
5k2b	ZMA	Adenosine receptor A2a	/	0.440
3sn6	P0G	Beta-2 adrenergic receptor	/	0.440