sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qbr | 910 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2qbr | 910 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 1.000 | |
| 2h4k | 509 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.745 | |
| 2b07 | 598 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.624 | |
| 2qbs | 024 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.600 | |
| 1jf7 | TBH | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.559 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.531 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.518 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.516 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.512 | |
| 1q6s | 214 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.512 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.509 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.505 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.504 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.503 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.502 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.497 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.497 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.493 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.489 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.489 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.488 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.487 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.485 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.484 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.483 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.483 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.483 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.483 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.480 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.478 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.478 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.476 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.476 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.475 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.475 | |
| 4h6p | FMN | Chromate reductase | / | 0.475 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.474 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.474 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.473 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.473 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 1rxj | BNI | Streptavidin | / | 0.472 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.472 | |
| 3arv | SAU | Chitinase A | / | 0.472 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.472 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.472 | |
| 4y1b | NAP | AntE | / | 0.472 | |
| 5dp2 | NAP | CurF | / | 0.472 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.471 | |
| 3p5s | AVU | CD38 molecule | / | 0.471 | |
| 4iae | 1DX | Alr2278 protein | / | 0.471 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.470 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.469 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.469 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.469 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.469 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.469 | |
| 1w1v | ALJ | Chitinase | / | 0.468 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.468 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.468 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.467 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.467 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.467 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.467 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.467 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.467 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1qv0 | CZH | Obelin | / | 0.466 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.465 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.465 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.465 | |
| 4j7g | TRH | PCZA361.3 | / | 0.465 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.464 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.464 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.464 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.464 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.463 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.463 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.463 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 1c7o | PPG | Hemolysin | / | 0.462 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.462 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.462 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.462 | |
| 1s7l | COA | Acetyl transferase | / | 0.462 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.462 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.462 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.462 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.462 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.461 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.461 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.461 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.461 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.461 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.461 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.461 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.461 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.460 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
| 2q0g | UPU | Poly(A) polymerase, putative | / | 0.460 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.460 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.459 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.459 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.459 | |
| 4jxr | ACO | Acetyltransferase | / | 0.459 | |
| 4phl | PIL | Phosphodiesterase | / | 0.459 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 1dtp | APU | Diphtheria toxin | / | 0.458 | |
| 1s36 | CEI | Obelin | / | 0.458 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.458 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.458 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.457 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.457 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.457 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.457 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3w5u | FAD | Ferredoxin | / | 0.457 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.457 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.457 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.456 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.456 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.456 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.456 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.456 | |
| 4j7h | TRH | PCZA361.3 | / | 0.456 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.456 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.456 | |
| 1u0h | ONM | Adenylate cyclase type 2 | / | 0.455 | |
| 1u0h | ONM | Adenylate cyclase type 5 | / | 0.455 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.455 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.455 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.455 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.455 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.455 | |
| 4hs4 | FMN | Chromate reductase | / | 0.455 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.454 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4iah | 1DX | Alr2278 protein | / | 0.454 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.454 | |
| 5doz | NDP | JamJ | / | 0.454 | |
| 1gaq | FAD | Ferredoxin | / | 0.453 | |
| 1i05 | LTL | Major urinary protein 6 | / | 0.453 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.453 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.453 | |
| 1syn | F89 | Thymidylate synthase | / | 0.453 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.453 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.453 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3dla | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.453 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.453 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.452 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.452 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.451 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.451 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.451 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.450 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4zob | LGC | Lin1840 protein | / | 0.450 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.449 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.449 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.449 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2yhu | WHF | Pteridine reductase | / | 0.449 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.449 | |
| 4kxj | P34 | Nucleoprotein | / | 0.449 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.449 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.449 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.448 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.448 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.448 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.448 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.447 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1qsn | COA | HAT A1 | / | 0.447 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.447 | |
| 2b56 | UTP | RNA editing complex protein MP57 | / | 0.447 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.447 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.447 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.447 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.446 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.446 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1zdw | FLV | Prenyltransferase | / | 0.446 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.446 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.446 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.446 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.446 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.445 | |
| 1pxg | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2gc8 | 885 | Polyprotein | / | 0.445 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.445 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 2qe2 | 452 | Polyprotein | / | 0.445 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.445 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.445 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.445 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4jzy | FAD | Cryptochrome-1 | / | 0.445 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.444 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.444 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.444 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.444 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.444 | |
| 2rtf | BTN | Streptavidin | / | 0.444 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.444 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.444 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.444 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.444 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 4k30 | NLG | N-acetylglutamate synthase, mitochondrial | 2.3.1.1 | 0.444 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.443 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.443 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 4die | C5P | Cytidylate kinase | / | 0.443 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.443 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.443 | |
| 4oaq | NDP | R-specific carbonyl reductase | / | 0.443 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.443 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.442 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.442 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.442 | |
| 3akl | ANP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.442 | |
| 3irh | DTP | HD domain protein | / | 0.442 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.442 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.442 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4hh4 | SAH | CcbJ | / | 0.442 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.442 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.442 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.441 | |
| 1dmw | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.441 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.441 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 2pda | TPP | Pyruvate synthase | / | 0.441 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.441 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3vaq | ADN | Putative adenosine kinase | / | 0.441 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.441 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.441 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.441 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.441 | |
| 4gbr | CAU | Beta-2 adrenergic receptor | / | 0.441 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.440 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1sre | HAB | Streptavidin | / | 0.440 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.440 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.440 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.440 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.440 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.440 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.440 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.440 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4rel | KMP | Glycosyltransferase | / | 0.440 | |
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.440 |