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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.11.000
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.657
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.618
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.614
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.604
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.601
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.601
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.598
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.595
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.590
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.574
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.572
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.569
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.564
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.557
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.556
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.556
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.553
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.553
2hog710Serine/threonine-protein kinase Chk12.7.11.10.550
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.550
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.548
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.545
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.545
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.543
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.542
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.540
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.539
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.537
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.537
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.534
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.534
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.533
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.531
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.530
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.530
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.530
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.529
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.529
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.528
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.527
2vrx447Aurora kinase B-A2.7.11.10.527
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.524
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.524
3zewSTUEphrin type-B receptor 42.7.10.10.524
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.521
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.521
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.520
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.519
5av2KMPDeath-associated protein kinase 12.7.11.10.519
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.518
1wvxBD4Death-associated protein kinase 12.7.11.10.517
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.517
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.517
3ztxZTXAurora kinase B-A2.7.11.10.517
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.516
2ijmADPFocal adhesion kinase 12.7.10.20.515
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.515
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.514
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.514
3bqr4RBDeath-associated protein kinase 3/0.513
4b99R4LMitogen-activated protein kinase 72.7.11.240.513
4yuqKS1Calmodulin-like domain protein kinase/0.512
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.511
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.511
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.511
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.510
3a62STURibosomal protein S6 kinase beta-12.7.11.10.510
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.510
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.510
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.510
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.510
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.510
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.508
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.507
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.506
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.504
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.504
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.504
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.504
1jklANPDeath-associated protein kinase 12.7.11.10.503
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.503
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.503
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.502
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.502
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.502
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.502
5auvAGIDeath-associated protein kinase 12.7.11.10.502
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.501
4iebANPCalmodulin-domain protein kinase 1/0.501
1zys199Serine/threonine-protein kinase Chk12.7.11.10.499
2j0m4STFocal adhesion kinase 12.7.10.20.499
3gubGUBDeath-associated protein kinase 12.7.11.10.499
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.498
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.498
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.497
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.496
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.496
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.495
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.495
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.494
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.493
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.493
3mvl38PMitogen-activated protein kinase 14/0.493
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.493
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.493
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.493
2ckeIQUDeath-associated protein kinase 2/0.492
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.492
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.492
4nka2K7Fibroblast growth factor receptor 1/0.492
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.491
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.491
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.491
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.491
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.491
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.490
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.490
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.490
4fv9E71Mitogen-activated protein kinase 12.7.11.240.490
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.489
4ysjADPCalmodulin-like domain protein kinase/0.489
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.487
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.487
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.487
5av3KMPDeath-associated protein kinase 12.7.11.10.487
1mqbANPEphrin type-A receptor 22.7.10.10.486
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.486
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.485
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.485
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.485
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.484
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.484
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.484
3w2o03PEpidermal growth factor receptor2.7.10.10.484
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.484
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.484
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.484
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.484
4pd6URINucleoside permease/0.484
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.483
3c4xATPRhodopsin kinase/0.483
3i60E86Mitogen-activated protein kinase 12.7.11.240.483
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.483
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.483
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.482
1yvj4STTyrosine-protein kinase JAK32.7.10.20.482
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.482
3t8oATPRhodopsin kinase/0.482
4f640S8Fibroblast growth factor receptor 1/0.482
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.482
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.482
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.482
3q92XNBKetohexokinase/0.481
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.481
2c6eHPMAurora kinase A2.7.11.10.480
2j0lANPFocal adhesion kinase 12.7.10.20.480
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.480
2vu3LZECyclin-dependent kinase 22.7.11.220.480
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.480
4ansVGHALK tyrosine kinase receptor2.7.10.10.480
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.480
4gt3ATPMitogen-activated protein kinase 12.7.11.240.480
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.479
2xp2VGHALK tyrosine kinase receptor2.7.10.10.479
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.479
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.478
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.478
3qaiXNNKetohexokinase/0.478
4i22IREEpidermal growth factor receptor2.7.10.10.478
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.477
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.477
2ojj82AMitogen-activated protein kinase 12.7.11.240.477
2vgpAD6Aurora kinase B-A2.7.11.10.477
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.477
5av4GENDeath-associated protein kinase 12.7.11.10.476
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.475
2j7t274Serine/threonine-protein kinase 102.7.11.10.475
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.475
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.475
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.475
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.474
2c475IDCasein kinase I isoform gamma-2/0.474
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.474
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.474
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.474
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.474
4wsqKSAAP2-associated protein kinase 12.7.11.10.474
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.473
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.473
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.473
2yaaATPDeath-associated protein kinase 2/0.473
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.473
4fv6E57Mitogen-activated protein kinase 12.7.11.240.473
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.472
2j0k4STFocal adhesion kinase 12.7.10.20.472
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.472
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.472
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.472
4grb0XGCasein kinase II subunit alpha2.7.11.10.472
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.471
3lltANPProtein serine/threonine kinase-1/0.471
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4jbpYPHAurora kinase A2.7.11.10.471
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.471
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.470
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.470
3nbwTR4Ketohexokinase/0.470
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.470
4h3qANPMitogen-activated protein kinase 12.7.11.240.470
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.470
4s33ANPMitogen-activated protein kinase 12.7.11.240.470
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.470
5e8wSTUTGF-beta receptor type-12.7.11.300.470
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.469
1xjdSTUProtein kinase C theta type2.7.11.130.469
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.469
3qa2XNAKetohexokinase/0.469
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.469
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.468
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.468
3hx4ANPCalmodulin-domain protein kinase 1/0.468
3oafOAGDihydrofolate reductase1.5.1.30.468
4anqVGHALK tyrosine kinase receptor2.7.10.10.468
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.468
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.468
1k6pXN3Gag-Pol polyprotein3.4.23.160.467
2x9fX9FEphrin type-B receptor 42.7.10.10.467
3c4wATPRhodopsin kinase/0.467
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.467
4btkDTQTau-tubulin kinase 12.7.11.10.467
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.466
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.466
3a7hATPSerine/threonine-protein kinase 242.7.11.10.466
3gu6ADPDeath-associated protein kinase 12.7.11.10.466
3my5RFZCyclin-dependent kinase 22.7.11.220.466
4bcmT7ZCyclin-dependent kinase 22.7.11.220.466
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.466
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.466
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.465
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.465
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.465
4bchT7ZCyclin-dependent kinase 92.7.11.220.465
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.465
5auwQUEDeath-associated protein kinase 12.7.11.10.465
1qvnFRIInterleukin-2/0.464
3dfcANPDeath-associated protein kinase 12.7.11.10.464
4jia1K3Tyrosine-protein kinase JAK2/0.464
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
1ppm0P1Penicillopepsin-13.4.23.200.463
2etm7PYFocal adhesion kinase 12.7.10.20.463
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.463
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.463
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.463
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.463
3zh8C58Protein kinase C iota type2.7.11.130.463
4c4g7RODual specificity protein kinase TTK2.7.12.10.463
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.463
4gu94GUFocal adhesion kinase 12.7.10.20.463
4j97ACPFibroblast growth factor receptor 2/0.463
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.463
1fvv107Cyclin-dependent kinase 22.7.11.220.462
2xvdAS6Ephrin type-B receptor 42.7.10.10.462
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.462
3fln3FNMitogen-activated protein kinase 14/0.462
3ortAGSSerine/threonine protein kinase/0.462
3sheI85MAP kinase-activated protein kinase 32.7.11.10.462
3t113T1Gag-Pol polyprotein3.4.23.160.462
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.462
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.462
4aotGW8Serine/threonine-protein kinase 102.7.11.10.462
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.462
4iaq2GM5-hydroxytryptamine receptor 1B/0.462
4jq8KJ8Epidermal growth factor receptor2.7.10.10.462
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.462
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1v9aSAHUncharacterized protein/0.461
2bfyH1NAurora kinase B-A2.7.11.10.461
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.461
2yfxVGHALK tyrosine kinase receptor2.7.10.10.461
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.461
3hl7I47Mitogen-activated protein kinase 14/0.461
3nc9TR3Ketohexokinase/0.461
3vryB43Tyrosine-protein kinase HCK2.7.10.20.461
4c4h7RODual specificity protein kinase TTK2.7.12.10.461
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.460
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.460
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.460
4k8aK8AFocal adhesion kinase 12.7.10.20.460
4s34ANPMitogen-activated protein kinase 12.7.11.240.460
5auxKMPDeath-associated protein kinase 12.7.11.10.460
1bygSTUTyrosine-protein kinase CSK/0.459
1k6cMK1Gag-Pol polyprotein3.4.23.160.459
2acxANPG protein-coupled receptor kinase 62.7.11.160.459
2zjwREFCasein kinase II subunit alpha2.7.11.10.459
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.459
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.459
4c3pACPAurora kinase A2.7.11.10.459
4fyn0VETyrosine-protein kinase SYK2.7.10.20.459
4g95OAGDihydrofolate reductase1.5.1.30.459
4hgt15GCasein kinase I isoform delta2.7.11.10.459
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.459
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.459
2uzbC75Cyclin-dependent kinase 22.7.11.220.458
2vd5BI8Myotonin-protein kinase2.7.11.10.458
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.458
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.458
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.458
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.458
4gk2L66Ephrin type-A receptor 32.7.10.10.458
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.458
4o0uADNAurora kinase A2.7.11.10.458
4qo9627Serine/threonine-protein kinase 242.7.11.10.458
1jkkANPDeath-associated protein kinase 12.7.11.10.457
1zrzBI1Protein kinase C iota type2.7.11.130.457
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.457
2om9AJAPeroxisome proliferator-activated receptor gamma/0.457
3q5iANPProtein kinase, putative/0.457
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4aguD15Cyclin-dependent kinase-like 1/0.457
4bgh3I6Cyclin-dependent kinase 22.7.11.220.457
4cd0AWJALK tyrosine kinase receptor2.7.10.10.457
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.457
4g170VNCasein kinase I isoform gamma-32.7.11.10.457
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.456
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.456
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.456
2j0j4STFocal adhesion kinase 12.7.10.20.456
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.456
3c4zADPRhodopsin kinase/0.456
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
5aaaVGHALK tyrosine kinase receptor2.7.10.10.456
2x6dX6DAurora kinase A2.7.11.10.455
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3bhy7CPDeath-associated protein kinase 3/0.455
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.455
3igoANPCalmodulin-domain protein kinase 1, putative/0.455
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.455
3wmxNADNAD dependent epimerase/dehydratase/0.455
1u54ACPActivated CDC42 kinase 1/0.454
2iw84SPCyclin-dependent kinase 22.7.11.220.454
3qc9ADPRhodopsin kinase/0.454
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.454
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.454
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.454
4fuxE75Mitogen-activated protein kinase 12.7.11.240.454
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.454
4iarERM5-hydroxytryptamine receptor 1B/0.454
4jajXU1Aurora kinase A2.7.11.10.454
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
1pkdUCNCyclin-dependent kinase 22.7.11.220.453
1wvySTUDeath-associated protein kinase 12.7.11.10.453
2w05FRTCyclin-dependent kinase 22.7.11.220.453
3at4CCKCasein kinase II subunit alpha2.7.11.10.453
3bu5ATPInsulin receptor2.7.10.10.453
3ggfGVDSerine/threonine-protein kinase 26/0.453
3gu7ADPDeath-associated protein kinase 12.7.11.10.453
3rkb12ZCyclin-dependent kinase 22.7.11.220.453
4dgmAGICasein kinase II subunit alpha2.7.11.10.453
4gmy0X5Tyrosine-protein kinase JAK2/0.453
4hvi19STyrosine-protein kinase JAK32.7.10.20.453
4ic7ANPMitogen-activated protein kinase 72.7.11.240.453
4jrvKJVEpidermal growth factor receptor2.7.10.10.453
4s32ANPMitogen-activated protein kinase 12.7.11.240.453
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.452
4a6nFADTetX family tetracycline inactivation enzyme/0.452
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.452
4e4m0NHTyrosine-protein kinase JAK2/0.452
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.452
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.452
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.452
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2in6839Wee1-like protein kinase2.7.10.20.451
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.451
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.451
3d7tSTUTyrosine-protein kinase CSK/0.451
3nwxKVSGag-Pol polyprotein3.4.23.160.451
4fmqANPMitogen-activated protein kinase 12.7.11.240.451
4g1wG1WMitogen-activated protein kinase 82.7.11.240.451
4jboWPHAurora kinase A2.7.11.10.451
4jqeANPCasein kinase II subunit alpha2.7.11.10.451
5aacVGHALK tyrosine kinase receptor2.7.10.10.451
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.450
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.450
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.450
2xa4AZ5Tyrosine-protein kinase JAK2/0.450
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.450
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.450
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.450
4at9UTPInterleukin enhancer-binding factor 2/0.450
4hys1BJMitogen-activated protein kinase 82.7.11.240.450
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.450
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.449
2izrBRKCasein kinase I isoform gamma-32.7.11.10.449
2izsBRQCasein kinase I isoform gamma-32.7.11.10.449
3h9f92MDual specificity protein kinase TTK2.7.12.10.449
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.449
3r9dX6BCyclin-dependent kinase 22.7.11.220.449
3zep1NXTyrosine-protein kinase JAK32.7.10.20.449
4gk3L87Ephrin type-A receptor 32.7.10.10.449
4jbqVX6Aurora kinase A2.7.11.10.449
4jnqFDAThioredoxin reductase/0.449
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.449
4o0wADNAurora kinase A2.7.11.10.449
4wkqIREEpidermal growth factor receptor2.7.10.10.449
1finATPCyclin-dependent kinase 22.7.11.220.448
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.448
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.448
1w0xOLOCyclin-dependent kinase 22.7.11.220.448
2hw1ANPKetohexokinase/0.448
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.448
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.448
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.448
3qlrNDPDihydrofolate reductase1.5.1.30.448
3tnwF18Cyclin-dependent kinase 22.7.11.220.448
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.448
4a99FADTetX family tetracycline inactivation enzyme/0.448
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.448
2a0cCK9Cyclin-dependent kinase 22.7.11.220.447
2of2547Tyrosine-protein kinase Lck2.7.10.20.447
2qo7ANPEphrin type-A receptor 32.7.10.10.447
3eb0DRKUncharacterized protein/0.447
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.447
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.447
4b8lA0PAurora kinase B-A2.7.11.10.447
4hvg19QTyrosine-protein kinase JAK32.7.10.20.447
4nb6444Nuclear receptor ROR-gamma/0.447
4y93746Tyrosine-protein kinase/0.447
1k6vXN2Gag-Pol polyprotein3.4.23.160.446
1rc0KT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.446
2wecPP5Penicillopepsin-13.4.23.200.446
3flzFLZMitogen-activated protein kinase 14/0.446
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.446
4f630S7Fibroblast growth factor receptor 1/0.446
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.446
5av047XDeath-associated protein kinase 12.7.11.10.446
5fwgGPRGlutathione S-transferase Mu 12.5.1.180.446
1f123HCHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.445
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.445
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.445
3uzp0CKCasein kinase I isoform delta2.7.11.10.445
4bcqTJFCyclin-dependent kinase 22.7.11.220.445
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.445
4looSB4Mitogen-activated protein kinase 14/0.445
4qnyANPMitogen activated protein kinase, putative/0.445
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.445
1jpaANPEphrin type-B receptor 22.7.10.10.444
1u4dDBQActivated CDC42 kinase 1/0.444
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.444
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.444
2btsU32Cyclin-dependent kinase 22.7.11.220.444
2hk51BMTyrosine-protein kinase HCK2.7.10.20.444
2x1nX1NCyclin-dependent kinase 22.7.11.220.444
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.444
3ggoNAIPrephenate dehydrogenase/0.444
3l8p0CEAngiopoietin-1 receptor2.7.10.10.444
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.444
4nks2M2Fibroblast growth factor receptor 1/0.444
2henADPEphrin type-B receptor 22.7.10.10.443
3axwTIDCasein kinase II subunit alpha2.7.11.10.443
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.443
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.443
3nux3NVCyclin-dependent kinase 62.7.11.220.443
3t2zFADSulfide-quinone reductase/0.443
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.443
4l9i8PRRhodopsin kinase/0.443
5e8xSTUTGF-beta receptor type-12.7.11.300.443
1eh4IC1Casein kinase I homolog 12.7.11.10.442
1v5eFADPyruvate oxidase/0.442
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.442
2fvdLIACyclin-dependent kinase 22.7.11.220.442
2upjU02Gag-Pol polyprotein3.4.23.160.442
2uzlC94Cyclin-dependent kinase 22.7.11.220.442
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.442
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.442
3ggpNADPrephenate dehydrogenase/0.442
3lxiCAMCytochrome P450/0.442
3vetADPnebramycin 5' synthase6.1.2.20.442
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.442
4gk4L90Ephrin type-A receptor 32.7.10.10.442
4hvh19RTyrosine-protein kinase JAK32.7.10.20.442
4id71G0Activated CDC42 kinase 1/0.442
4jrnANPRhoptry kinase family protein/0.442
4kba1QMCasein kinase I isoform delta2.7.11.10.442
5aut2ANDeath-associated protein kinase 12.7.11.10.442
1bxqPP8Penicillopepsin-13.4.23.200.441
1di9MSQMitogen-activated protein kinase 14/0.441
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.441
2itzIREEpidermal growth factor receptor2.7.10.10.441
2xikJ60Serine/threonine-protein kinase 252.7.11.10.441
2zmd537Dual specificity protein kinase TTK2.7.12.10.441
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.441
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.441
3rak03ZCyclin-dependent kinase 22.7.11.220.441
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.441
4kb81QNCasein kinase I isoform delta2.7.11.10.441
1b15NAEAlcohol dehydrogenase1.1.1.10.440
1ig1ANPDeath-associated protein kinase 12.7.11.10.440
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.440
1v79FR7Adenosine deaminase3.5.4.40.440
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.440
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2qo9ANPEphrin type-A receptor 32.7.10.10.440
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.440
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.440
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.440
3oxv478Gag-Pol polyprotein3.4.23.160.440
3pxkPXKFocal adhesion kinase 12.7.10.20.440
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.440
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.440
4j99ACPFibroblast growth factor receptor 2/0.440
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.440
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
5e8ySTUTGF-beta receptor type-22.7.11.300.440
5e92ANPTGF-beta receptor type-22.7.11.300.440