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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.11.000
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.872
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.723
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.713
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.665
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.654
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.619
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.618
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.615
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.609
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.609
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.597
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.588
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.586
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.576
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.576
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.563
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.554
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.547
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.547
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.546
4b99R4LMitogen-activated protein kinase 72.7.11.240.546
4iebANPCalmodulin-domain protein kinase 1/0.546
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.542
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.538
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.536
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.535
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.535
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.532
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.532
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.531
3bqr4RBDeath-associated protein kinase 3/0.530
2hog710Serine/threonine-protein kinase Chk12.7.11.10.529
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.528
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.528
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.527
1wvxBD4Death-associated protein kinase 12.7.11.10.523
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.521
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.519
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.519
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.518
2c475IDCasein kinase I isoform gamma-2/0.517
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.517
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.517
4c4h7RODual specificity protein kinase TTK2.7.12.10.516
4gt3ATPMitogen-activated protein kinase 12.7.11.240.516
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.515
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.514
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.514
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.513
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.512
4ansVGHALK tyrosine kinase receptor2.7.10.10.512
3a62STURibosomal protein S6 kinase beta-12.7.11.10.511
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.511
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.508
1jklANPDeath-associated protein kinase 12.7.11.10.507
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.507
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.507
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.507
4fv9E71Mitogen-activated protein kinase 12.7.11.240.506
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.505
2yfxVGHALK tyrosine kinase receptor2.7.10.10.505
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.505
3i60E86Mitogen-activated protein kinase 12.7.11.240.505
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.505
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.505
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.505
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.504
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.504
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.504
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.503
3zewSTUEphrin type-B receptor 42.7.10.10.503
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.503
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.502
4wsqKSAAP2-associated protein kinase 12.7.11.10.502
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.501
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.501
2ckeIQUDeath-associated protein kinase 2/0.500
2etm7PYFocal adhesion kinase 12.7.10.20.500
3q92XNBKetohexokinase/0.500
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.499
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.498
1zys199Serine/threonine-protein kinase Chk12.7.11.10.498
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.498
4iaq2GM5-hydroxytryptamine receptor 1B/0.498
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.497
4i22IREEpidermal growth factor receptor2.7.10.10.497
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.496
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.495
5av2KMPDeath-associated protein kinase 12.7.11.10.495
3hx4ANPCalmodulin-domain protein kinase 1/0.494
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.494
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.494
4joa3DKALK tyrosine kinase receptor2.7.10.10.494
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.494
2vrx447Aurora kinase B-A2.7.11.10.493
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.493
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.493
3t8oATPRhodopsin kinase/0.493
5av3KMPDeath-associated protein kinase 12.7.11.10.493
1yvj4STTyrosine-protein kinase JAK32.7.10.20.491
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.491
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.491
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.491
2of2547Tyrosine-protein kinase Lck2.7.10.20.491
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.491
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.490
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.490
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.490
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.489
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.489
3w2o03PEpidermal growth factor receptor2.7.10.10.489
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.489
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.488
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.488
5auwQUEDeath-associated protein kinase 12.7.11.10.488
2ijmADPFocal adhesion kinase 12.7.10.20.487
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.487
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.487
1xjdSTUProtein kinase C theta type2.7.11.130.486
2j0j4STFocal adhesion kinase 12.7.10.20.486
3gubGUBDeath-associated protein kinase 12.7.11.10.486
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.486
3qaiXNNKetohexokinase/0.486
2j0m4STFocal adhesion kinase 12.7.10.20.485
2xvdAS6Ephrin type-B receptor 42.7.10.10.485
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.485
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.485
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.485
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.485
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.484
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.484
2vd5BI8Myotonin-protein kinase2.7.11.10.484
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.483
2hk51BMTyrosine-protein kinase HCK2.7.10.20.483
2j7t274Serine/threonine-protein kinase 102.7.11.10.482
3c4xATPRhodopsin kinase/0.482
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.482
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.482
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
4bcmT7ZCyclin-dependent kinase 22.7.11.220.482
4fuxE75Mitogen-activated protein kinase 12.7.11.240.482
4gk4L90Ephrin type-A receptor 32.7.10.10.482
4gmy0X5Tyrosine-protein kinase JAK2/0.482
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.482
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.481
2c6eHPMAurora kinase A2.7.11.10.481
2vu3LZECyclin-dependent kinase 22.7.11.220.481
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.481
4anqVGHALK tyrosine kinase receptor2.7.10.10.481
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.481
4c4g7RODual specificity protein kinase TTK2.7.12.10.481
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.481
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.480
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.480
3at4CCKCasein kinase II subunit alpha2.7.11.10.480
3axwTIDCasein kinase II subunit alpha2.7.11.10.480
4grb0XGCasein kinase II subunit alpha2.7.11.10.480
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.480
5av4GENDeath-associated protein kinase 12.7.11.10.480
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.479
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.479
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.478
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.478
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.478
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.478
4fz60VGTyrosine-protein kinase SYK2.7.10.20.478
4hgt15GCasein kinase I isoform delta2.7.11.10.478
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.477
2xp2VGHALK tyrosine kinase receptor2.7.10.10.477
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.477
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.477
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.477
4nka2K7Fibroblast growth factor receptor 1/0.477
2yaaATPDeath-associated protein kinase 2/0.476
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.476
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.476
4jia1K3Tyrosine-protein kinase JAK2/0.476
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.476
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.475
2uzbC75Cyclin-dependent kinase 22.7.11.220.475
4c4iX20Dual specificity protein kinase TTK2.7.12.10.475
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4fv6E57Mitogen-activated protein kinase 12.7.11.240.475
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.474
3gu6ADPDeath-associated protein kinase 12.7.11.10.474
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.474
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.474
3r9dX6BCyclin-dependent kinase 22.7.11.220.474
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.474
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.474
4j97ACPFibroblast growth factor receptor 2/0.474
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.473
2qo9ANPEphrin type-A receptor 32.7.10.10.473
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.473
3gc9B45Mitogen-activated protein kinase 112.7.11.240.473
3uvqFS8Mitogen-activated protein kinase 14/0.473
3zh8C58Protein kinase C iota type2.7.11.130.473
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.473
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.473
4iarERM5-hydroxytryptamine receptor 1B/0.473
4qo9627Serine/threonine-protein kinase 242.7.11.10.473
5aaaVGHALK tyrosine kinase receptor2.7.10.10.473
1mqbANPEphrin type-A receptor 22.7.10.10.472
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.472
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.472
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.472
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.472
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.472
4c62XWWTyrosine-protein kinase JAK2/0.472
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.472
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.471
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4bchT7ZCyclin-dependent kinase 92.7.11.220.471
4jbpYPHAurora kinase A2.7.11.10.471
4nks2M2Fibroblast growth factor receptor 1/0.471
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.471
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.471
5upjUINGag-Pol polyprotein/0.471
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2j0lANPFocal adhesion kinase 12.7.10.20.470
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.470
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.470
1oiyN41Cyclin-dependent kinase 22.7.11.220.469
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.469
4cd0AWJALK tyrosine kinase receptor2.7.10.10.469
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.469
1oi9N20Cyclin-dependent kinase 22.7.11.220.468
2zmd537Dual specificity protein kinase TTK2.7.12.10.468
3nc9TR3Ketohexokinase/0.468
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.468
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.468
4yuqKS1Calmodulin-like domain protein kinase/0.468
2ituITQEpidermal growth factor receptor2.7.10.10.467
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4ez50RSCyclin-dependent kinase 62.7.11.220.467
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.467
1pjkANPCasein kinase II subunit alpha2.7.11.10.466
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.466
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4g170VNCasein kinase I isoform gamma-32.7.11.10.466
4g1wG1WMitogen-activated protein kinase 82.7.11.240.466
5dr9SKEAurora kinase A2.7.11.10.466
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.465
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.465
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.465
3il1B5DGlutamate receptor 2/0.465
3vryB43Tyrosine-protein kinase HCK2.7.10.20.465
3ztxZTXAurora kinase B-A2.7.11.10.465
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.465
4riyADPEpidermal growth factor receptor2.7.10.10.465
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
1c70L75Protease/0.464
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.464
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.464
1zyjBI5Mitogen-activated protein kinase 14/0.464
2c7xNRBCytochrome P450 monooxygenase PikC/0.464
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.464
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.464
3bu5ATPInsulin receptor2.7.10.10.464
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
3qtuX44Cyclin-dependent kinase 22.7.11.220.464
3vetADPnebramycin 5' synthase6.1.2.20.464
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.464
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.464
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.464
4hys1BJMitogen-activated protein kinase 82.7.11.240.464
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2ca0PXICytochrome P450 monooxygenase PikC/0.463
2fde385Gag-Pol polyprotein3.4.23.160.463
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.463
3eb0DRKUncharacterized protein/0.463
3nbwTR4Ketohexokinase/0.463
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
3rak03ZCyclin-dependent kinase 22.7.11.220.463
4aguD15Cyclin-dependent kinase-like 1/0.463
4c4f7CEDual specificity protein kinase TTK2.7.12.10.463
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.463
5aacVGHALK tyrosine kinase receptor2.7.10.10.463
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.462
2of4979Tyrosine-protein kinase Lck2.7.10.20.462
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.462
3my5RFZCyclin-dependent kinase 22.7.11.220.462
3w2sW2REpidermal growth factor receptor2.7.10.10.462
4fnyI3KALK tyrosine kinase receptor2.7.10.10.462
4h3qANPMitogen-activated protein kinase 12.7.11.240.462
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.462
5ap57RODual specificity protein kinase TTK2.7.12.10.462
1fg62NCGag-Pol polyprotein3.4.23.160.461
2izrBRKCasein kinase I isoform gamma-32.7.11.10.461
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.461
2x9fX9FEphrin type-B receptor 42.7.10.10.461
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3q9xEMOCasein kinase II subunit alpha2.7.11.10.461
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.461
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.461
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4hvg19QTyrosine-protein kinase JAK32.7.10.20.461
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.461
4kb81QNCasein kinase I isoform delta2.7.11.10.461
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.461
5uviZMAAdenosine receptor A2a/0.461
1fm4DXCMajor pollen allergen Bet v 1-L/0.460
2bpv1INGag-Pol polyprotein3.4.23.160.460
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.460
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.460
3q5iANPProtein kinase, putative/0.460
3qa2XNAKetohexokinase/0.460
4bcnT9NCyclin-dependent kinase 22.7.11.220.460
4fob0USALK tyrosine kinase receptor2.7.10.10.460
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.460
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.460
4ysjADPCalmodulin-like domain protein kinase/0.460
1h1r6CPCyclin-dependent kinase 22.7.11.220.459
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.459
2bpw1INGag-Pol polyprotein3.4.23.160.459
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.459
2i4vDJRV-1 protease/0.459
2izsBRQCasein kinase I isoform gamma-32.7.11.10.459
2r43G3GGag-Pol polyprotein3.4.23.160.459
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.459
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.459
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.459
3tl9ROCGag-Pol polyprotein3.4.23.160.459
3vquO22Dual specificity protein kinase TTK2.7.12.10.459
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.459
4f640S8Fibroblast growth factor receptor 1/0.459
4fv8E63Mitogen-activated protein kinase 12.7.11.240.459
4k8aK8AFocal adhesion kinase 12.7.10.20.459
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.459
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.459
1npa3NHGag-Pol polyprotein3.4.23.160.458
1npwLGZGag-Pol polyprotein3.4.23.160.458
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.458
3a7hATPSerine/threonine-protein kinase 242.7.11.10.458
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.458
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.458
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.458
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.458
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2c4g514Cyclin-dependent kinase 22.7.11.220.457
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2ojj82AMitogen-activated protein kinase 12.7.11.240.457
3ekt017Gag-Pol polyprotein3.4.23.160.457
3h0sB38Acetyl-CoA carboxylase/0.457
3lltANPProtein serine/threonine kinase-1/0.457
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.457
4gk2L66Ephrin type-A receptor 32.7.10.10.457
4id71G0Activated CDC42 kinase 1/0.457
4o0uADNAurora kinase A2.7.11.10.457
1h1s4SPCyclin-dependent kinase 22.7.11.220.456
1qbu846Gag-Pol polyprotein3.4.23.160.456
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.456
2itnANPEpidermal growth factor receptor2.7.10.10.456
2yn8STUEphrin type-B receptor 42.7.10.10.456
3l8p0CEAngiopoietin-1 receptor2.7.10.10.456
4bcqTJFCyclin-dependent kinase 22.7.11.220.456
4bgh3I6Cyclin-dependent kinase 22.7.11.220.456
4e4m0NHTyrosine-protein kinase JAK2/0.456
4hvi19STyrosine-protein kinase JAK32.7.10.20.456
5e8xSTUTGF-beta receptor type-12.7.11.300.456
1pkdUCNCyclin-dependent kinase 22.7.11.220.455
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.455
2qnnQN1Gag-Pol polyprotein3.4.23.160.455
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.455
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.455
3mvl38PMitogen-activated protein kinase 14/0.455
4c3pACPAurora kinase A2.7.11.10.455
4e730NRMitogen-activated protein kinase 82.7.11.240.455
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
5k2aZMAAdenosine receptor A2a/0.455
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.454
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.454
3i0rRT3Gag-Pol polyprotein2.7.7.490.454
3lfqA28Cyclin-dependent kinase 22.7.11.220.454
3ormAGSSerine/threonine protein kinase/0.454
3upjU03Gag-Pol polyprotein/0.454
4hvh19RTyrosine-protein kinase JAK32.7.10.20.454
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.454
1b6pPI7Gag-Pol polyprotein3.4.23.160.453
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.453
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.453
2pwcG3GGag-Pol polyprotein3.4.23.160.453
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.453
3i2l2NCProtease/0.453
3jw2017Gag-Pol polyprotein3.4.23.160.453
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4qgiROCGag-Pol polyprotein3.4.23.160.453
5auxKMPDeath-associated protein kinase 12.7.11.10.453
5av047XDeath-associated protein kinase 12.7.11.10.453
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.452
2nmxM25Carbonic anhydrase 14.2.1.10.452
2xyeCXGGag-Pol polyprotein/0.452
3ekwDR7Gag-Pol polyprotein3.4.23.160.452
3iw4LW4Protein kinase C alpha type2.7.11.130.452
3sheI85MAP kinase-activated protein kinase 32.7.11.10.452
3zxtACPDeath-associated protein kinase 12.7.11.10.452
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
4gk3L87Ephrin type-A receptor 32.7.10.10.452
4i231C9Epidermal growth factor receptor2.7.10.10.452
4xlvACPInsulin receptor2.7.10.10.452
5auvAGIDeath-associated protein kinase 12.7.11.10.452
5dt0SKEAurora kinase A2.7.11.10.452
1cm8ANPMitogen-activated protein kinase 12/0.451
1jld0PPGag-Pol polyprotein/0.451
1muiAB1Protease/0.451
1u54ACPActivated CDC42 kinase 1/0.451
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.451
1wbmBLLPol protein/0.451
2cej1AHPol protein/0.451
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.451
2qoqANPEphrin type-A receptor 32.7.10.10.451
2r3jSCJCyclin-dependent kinase 22.7.11.220.451
2wipP49Cyclin-dependent kinase 22.7.11.220.451
3hl7I47Mitogen-activated protein kinase 14/0.451
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.451
3zdu38RCyclin-dependent kinase-like 32.7.11.220.451
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.451
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4s34ANPMitogen-activated protein kinase 12.7.11.240.451
1aq1STUCyclin-dependent kinase 22.7.11.220.450
1ec0BEDGag-Pol polyprotein3.4.23.160.450
1fvt106Cyclin-dependent kinase 22.7.11.220.450
1hsgMK1Gag-Pol polyprotein/0.450
1idb0DOGag-Pol polyprotein/0.450
1sh9RITGag-Pol polyprotein3.4.23.160.450
1vyzN5BCyclin-dependent kinase 22.7.11.220.450
2i40BLZCyclin-dependent kinase 22.7.11.220.450
2x6dX6DAurora kinase A2.7.11.10.450
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.450
3d1yROCGag-Pol polyprotein3.4.23.160.450
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.450
3lctADPALK tyrosine kinase receptor2.7.10.10.450
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3nynSGVG protein-coupled receptor kinase 62.7.11.160.450
3ral04ZCyclin-dependent kinase 22.7.11.220.450
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.450
3zep1NXTyrosine-protein kinase JAK32.7.10.20.450
4fx360KCyclin-dependent kinase 22.7.11.220.450
4gu94GUFocal adhesion kinase 12.7.10.20.450
4l9i8PRRhodopsin kinase/0.450
4wkqIREEpidermal growth factor receptor2.7.10.10.450
1bdrIM1Gag-Pol polyprotein3.4.23.160.449
1hiiC20Gag-Pol polyprotein/0.449
1me8RVPInosine-5'-monophosphate dehydrogenase/0.449
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.449
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.449
2f2cAP9Cyclin-dependent kinase 62.7.11.220.449
2j0k4STFocal adhesion kinase 12.7.10.20.449
2vv9IM9Cyclin-dependent kinase 22.7.11.220.449
2w05FRTCyclin-dependent kinase 22.7.11.220.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.449
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.449
4hgs15GCasein kinase I isoform gamma-32.7.11.10.449
4jboWPHAurora kinase A2.7.11.10.449
4nc3ERM5-hydroxytryptamine receptor 2B/0.449
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
2zjwREFCasein kinase II subunit alpha2.7.11.10.448
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.448
3ac1KZITyrosine-protein kinase Lck2.7.10.20.448
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.448
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.448
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.448
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.448
4btkDTQTau-tubulin kinase 12.7.11.10.448
4eok4SPCyclin-dependent kinase 22.7.11.220.448
4g6oE28Mitogen-activated protein kinase 12.7.11.240.448
4kba1QMCasein kinase I isoform delta2.7.11.10.448
4qmlANPSerine/threonine-protein kinase 242.7.11.10.448
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.448
1hxwRITGag-Pol polyprotein/0.447
2hw1ANPKetohexokinase/0.447
2ittAEEEpidermal growth factor receptor2.7.10.10.447
2pwlACPFibroblast growth factor receptor 2/0.447
3sa9A68Protease/0.447
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.447
3u4uLNHCasein kinase II subunit alpha2.7.11.10.447
4f630S7Fibroblast growth factor receptor 1/0.447
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
1ebwBEIGag-Pol polyprotein3.4.23.160.446
1meuDMPGag-Pol polyprotein3.4.23.160.446
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.446
3be9P04Casein kinase II subunit alpha2.7.11.10.446
4g160VMCasein kinase I isoform gamma-32.7.11.10.446
1finATPCyclin-dependent kinase 22.7.11.220.445
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.445
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.445
2qd7065Gag-Pol polyprotein3.4.23.160.445
2upjU02Gag-Pol polyprotein3.4.23.160.445
2xb7GUIALK tyrosine kinase receptor2.7.10.10.445
3el4ROCGag-Pol polyprotein3.4.23.160.445
3ggpNADPrephenate dehydrogenase/0.445
3nup3NUCyclin-dependent kinase 62.7.11.220.445
3qpjN4IGag-Pol polyprotein3.4.23.160.445
3rkb12ZCyclin-dependent kinase 22.7.11.220.445
3w3dATPActin, gamma-enteric smooth muscle/0.445
4c57FEFCyclin-G-associated kinase2.7.11.10.445
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.445
4jqeANPCasein kinase II subunit alpha2.7.11.10.445
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.445
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
5dosATPAurora kinase A2.7.11.10.445
1ebyBEBGag-Pol polyprotein3.4.23.160.444
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.444
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.444
1wvySTUDeath-associated protein kinase 12.7.11.10.444
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.444
2in6839Wee1-like protein kinase2.7.10.20.444
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.444
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.444
3dfcANPDeath-associated protein kinase 12.7.11.10.444
3gi5K62Gag-Pol polyprotein/0.444
3i6oGR6Gag-Pol polyprotein3.4.23.160.444
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.444
3oom507Activin receptor type-12.7.11.300.444
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.444
3qlrNDPDihydrofolate reductase1.5.1.30.444
3qruX19Cyclin-dependent kinase 22.7.11.220.444
3vewADPnebramycin 5' synthase6.1.2.20.444
3vvh4BMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
3zpuM8BGag-Pol polyprotein3.4.23.160.444
4eol1ROCyclin-dependent kinase 22.7.11.220.444
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.444
4ic7ANPMitogen-activated protein kinase 72.7.11.240.444
4l98LRGPeroxisome proliferator-activated receptor gamma/0.444
5auzGENDeath-associated protein kinase 12.7.11.10.444
1bai0Q4Gag-Pro polyprotein/0.443
1tvoFRZMitogen-activated protein kinase 12.7.11.240.443
2qd8065Gag-Pol polyprotein3.4.23.160.443
2qo7ANPEphrin type-A receptor 32.7.10.10.443
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.443
3e5aVX6Aurora kinase A2.7.11.10.443
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.443
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3tnwF18Cyclin-dependent kinase 22.7.11.220.443
3vfa031Gag-Pol polyprotein3.4.23.160.443
3zk5Z18Cytochrome P450 monooxygenase PikC/0.443
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.443
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.443
4btjATPTau-tubulin kinase 12.7.11.10.443
4erwSTUCyclin-dependent kinase 22.7.11.220.443
4hjfC2EGGDEF family protein/0.443
4ib4ERM5-hydroxytryptamine receptor 2B/0.443
4jq8KJ8Epidermal growth factor receptor2.7.10.10.443
5cvfATPCasein kinase II subunit alpha2.7.11.10.443
1ec3MS3Gag-Pol polyprotein3.4.23.160.442
1jkkANPDeath-associated protein kinase 12.7.11.10.442
1ke5LS1Cyclin-dependent kinase 22.7.11.220.442
1mtrPI6Gag-Pol polyprotein3.4.23.160.442
1tcxIM1Gag-Pol polyprotein3.4.23.160.442
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.442
1v9aSAHUncharacterized protein/0.442
1wbk568Pol protein/0.442
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.442
2hs2017Protease/0.442
2uy0HV1Gag-Pol polyprotein3.4.23.160.442
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.442
2xa4AZ5Tyrosine-protein kinase JAK2/0.442
3bhy7CPDeath-associated protein kinase 3/0.442
3gu83GUDeath-associated protein kinase 12.7.11.10.442
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.442
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.442
4c58824Cyclin-G-associated kinase2.7.11.10.442
4d58BI9Focal adhesion kinase 12.7.10.20.442
4dqe017Gag-Pol polyprotein/0.442
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.442
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1g35AHFGag-Pol polyprotein3.4.23.160.441
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.441
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.441
1yt9OISGag-Pol polyprotein/0.441
2acxANPG protein-coupled receptor kinase 62.7.11.160.441
2bpy3INGag-Pol polyprotein3.4.23.160.441
2qd6065Gag-Pol polyprotein3.4.23.160.441
2vgoAD5Aurora kinase B-A2.7.11.10.441
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.441
2z97CAMCamphor 5-monooxygenase1.14.15.10.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3nux3NVCyclin-dependent kinase 62.7.11.220.441
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.441
3uli1N3Cyclin-dependent kinase 22.7.11.220.441
4aotGW8Serine/threonine-protein kinase 102.7.11.10.441
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.441
4hyu1BKMitogen-activated protein kinase 82.7.11.240.441
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.441
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.441
1hpoUNIGag-Pol polyprotein3.4.23.160.440
1j39UPGDNA beta-glucosyltransferase/0.440
1jpaANPEphrin type-B receptor 22.7.10.10.440
1ndeMONEstrogen receptor beta/0.440
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.440
1u4dDBQActivated CDC42 kinase 1/0.440
1w5vBE3Gag-Pol polyprotein3.4.23.160.440
2h96893Mitogen-activated protein kinase 82.7.11.240.440
2vgpAD6Aurora kinase B-A2.7.11.10.440
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.440
3emg685Tyrosine-protein kinase SYK2.7.10.20.440
3h6vNS6Glutamate receptor 2/0.440
3h9f92MDual specificity protein kinase TTK2.7.12.10.440
3lzs017Gag-Pol polyprotein3.4.23.160.440
3qzfX66Cyclin-dependent kinase 22.7.11.220.440
3s0o50ZCyclin-dependent kinase 22.7.11.220.440
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.440
4dqc017Gag-Pol polyprotein/0.440
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4i7fNVEGag-Pol polyprotein2.7.7.490.440
4nb6444Nuclear receptor ROR-gamma/0.440
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.440
5e8wSTUTGF-beta receptor type-12.7.11.300.440