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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.11.000
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.616
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.599
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.599
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.588
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.583
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.580
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.578
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.578
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.577
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.570
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.569
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.568
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.568
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.560
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.557
2hog710Serine/threonine-protein kinase Chk12.7.11.10.554
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.552
3zh8C58Protein kinase C iota type2.7.11.130.552
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.551
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.548
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.548
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.547
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.546
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.546
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.546
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.545
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.543
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.542
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.541
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.540
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.530
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.530
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.530
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.529
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.527
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.527
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.526
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.525
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.525
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.523
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.523
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.523
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.523
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.520
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.519
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.518
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.515
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.514
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.514
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.513
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.512
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.512
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.512
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.511
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.511
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.511
2j0lANPFocal adhesion kinase 12.7.10.20.508
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.507
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.507
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.504
4jia1K3Tyrosine-protein kinase JAK2/0.504
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.502
3ggfGVDSerine/threonine-protein kinase 26/0.502
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.501
3a7hATPSerine/threonine-protein kinase 242.7.11.10.500
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.499
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.498
3t8oATPRhodopsin kinase/0.497
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.496
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.496
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.495
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.495
4ysjADPCalmodulin-like domain protein kinase/0.495
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.494
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.494
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.492
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.491
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.490
3axwTIDCasein kinase II subunit alpha2.7.11.10.490
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.490
5auvAGIDeath-associated protein kinase 12.7.11.10.490
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.489
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.488
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
3rni21ZCyclin-dependent kinase 22.7.11.220.488
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.488
4gmy0X5Tyrosine-protein kinase JAK2/0.488
2vd5BI8Myotonin-protein kinase2.7.11.10.487
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.486
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.486
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.485
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.484
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.484
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.484
3qyw6PBMitogen-activated protein kinase 12.7.11.240.484
4grb0XGCasein kinase II subunit alpha2.7.11.10.484
4qmlANPSerine/threonine-protein kinase 242.7.11.10.484
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.483
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.483
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.482
2wotZZGTGF-beta receptor type-12.7.11.300.482
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.482
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.481
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.481
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.481
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.480
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.480
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.480
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.480
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.479
2izuP01Casein kinase I isoform gamma-32.7.11.10.479
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.479
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.479
1xl2189Gag-Pol polyprotein3.4.23.160.478
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.478
3pxkPXKFocal adhesion kinase 12.7.10.20.478
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.477
1vjy460TGF-beta receptor type-12.7.11.300.477
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.477
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.477
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.477
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.476
2in6839Wee1-like protein kinase2.7.10.20.475
3gubGUBDeath-associated protein kinase 12.7.11.10.475
4nj32KDCyclin-dependent kinase 22.7.11.220.475
3at4CCKCasein kinase II subunit alpha2.7.11.10.474
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.474
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.474
5av2KMPDeath-associated protein kinase 12.7.11.10.474
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.473
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.473
2pwlACPFibroblast growth factor receptor 2/0.473
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.473
5auwQUEDeath-associated protein kinase 12.7.11.10.473
1zrzBI1Protein kinase C iota type2.7.11.130.472
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.472
2x1nX1NCyclin-dependent kinase 22.7.11.220.472
3q9xEMOCasein kinase II subunit alpha2.7.11.10.472
1pjkANPCasein kinase II subunit alpha2.7.11.10.471
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.471
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.471
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.471
4fob0USALK tyrosine kinase receptor2.7.10.10.471
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.471
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.471
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.471
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.471
2ijmATPFocal adhesion kinase 12.7.10.20.470
2yy8MTAtRNA (cytidine(56)-2'-O)-methyltransferase/0.470
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1h1s4SPCyclin-dependent kinase 22.7.11.220.469
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.469
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.468
2j0m4STFocal adhesion kinase 12.7.10.20.468
3lltANPProtein serine/threonine kinase-1/0.468
3w551FMMitogen-activated protein kinase 12.7.11.240.468
5e8ySTUTGF-beta receptor type-22.7.11.300.468
2vgoAD5Aurora kinase B-A2.7.11.10.467
2xa4AZ5Tyrosine-protein kinase JAK2/0.467
4fv6E57Mitogen-activated protein kinase 12.7.11.240.467
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.467
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.466
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3ezrEZRCyclin-dependent kinase 22.7.11.220.465
3zep1NXTyrosine-protein kinase JAK32.7.10.20.465
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.465
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.465
4i22IREEpidermal growth factor receptor2.7.10.10.465
2jkqVG8Focal adhesion kinase 12.7.10.20.464
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.464
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.464
3a62STURibosomal protein S6 kinase beta-12.7.11.10.464
4fv9E71Mitogen-activated protein kinase 12.7.11.240.464
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.463
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.463
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.463
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.463
3eljGS7Mitogen-activated protein kinase 82.7.11.240.463
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.463
4bcmT7ZCyclin-dependent kinase 22.7.11.220.463
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.463
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.463
4ryvZEAProtein LlR18A/0.463
1aq1STUCyclin-dependent kinase 22.7.11.220.462
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.462
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.462
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.462
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.462
4h3qANPMitogen-activated protein kinase 12.7.11.240.462
2etm7PYFocal adhesion kinase 12.7.10.20.461
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.461
3bqr4RBDeath-associated protein kinase 3/0.461
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.461
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.461
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
5ap7SVEDual specificity protein kinase TTK2.7.12.10.461
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.460
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.460
4e730NRMitogen-activated protein kinase 82.7.11.240.460
4jqeANPCasein kinase II subunit alpha2.7.11.10.460
4k8aK8AFocal adhesion kinase 12.7.10.20.460
4y95746Tyrosine-protein kinase/0.460
3bhy7CPDeath-associated protein kinase 3/0.459
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.459
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.459
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.458
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3igoANPCalmodulin-domain protein kinase 1, putative/0.458
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.458
4d58BI9Focal adhesion kinase 12.7.10.20.458
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.458
4gu610NFocal adhesion kinase 12.7.10.20.458
2uzbC75Cyclin-dependent kinase 22.7.11.220.457
2y9qANPMitogen-activated protein kinase 12.7.11.240.457
4d4sBI9Focal adhesion kinase 12.7.10.20.457
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.457
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.457
1w0xOLOCyclin-dependent kinase 22.7.11.220.456
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.456
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.456
3gu83GUDeath-associated protein kinase 12.7.11.10.456
3nwxKVSGag-Pol polyprotein3.4.23.160.456
3oibFDAPutative acyl-CoA dehydrogenase/0.456
3tnwF18Cyclin-dependent kinase 22.7.11.220.456
4b99R4LMitogen-activated protein kinase 72.7.11.240.456
4fkg4CKCyclin-dependent kinase 22.7.11.220.456
4j97ACPFibroblast growth factor receptor 2/0.456
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.456
4wboANWRhodopsin kinase/0.456
1oirHDYCyclin-dependent kinase 22.7.11.220.455
1u4dDBQActivated CDC42 kinase 1/0.455
1xjdSTUProtein kinase C theta type2.7.11.130.455
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.455
3lfqA28Cyclin-dependent kinase 22.7.11.220.455
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.455
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.455
4gk4L90Ephrin type-A receptor 32.7.10.10.455
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.454
2bfyH1NAurora kinase B-A2.7.11.10.454
2ckeIQUDeath-associated protein kinase 2/0.454
2i40BLZCyclin-dependent kinase 22.7.11.220.454
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.454
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.454
2xvdAS6Ephrin type-B receptor 42.7.10.10.454
3q9wEMOCasein kinase II subunit alpha2.7.11.10.454
3ztxZTXAurora kinase B-A2.7.11.10.454
4a6cQG9Gag-Pol polyprotein3.4.23.160.454
4fkt48KCyclin-dependent kinase 22.7.11.220.454
4hgs15GCasein kinase I isoform gamma-32.7.11.10.454
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.454
2vu3LZECyclin-dependent kinase 22.7.11.220.453
3iok1P6Tyrosine-protein kinase JAK2/0.453
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.453
3sheI85MAP kinase-activated protein kinase 32.7.11.10.453
3vs3VSETyrosine-protein kinase HCK2.7.10.20.453
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4c4f7CEDual specificity protein kinase TTK2.7.12.10.453
4dgnLU2Casein kinase II subunit alpha2.7.11.10.453
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.453
4qmpDKISerine/threonine-protein kinase 242.7.11.10.453
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.453
3sn6P0GBeta-2 adrenergic receptor/0.453
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.452
1pxoCK7Cyclin-dependent kinase 22.7.11.220.452
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.452
1wvxBD4Death-associated protein kinase 12.7.11.10.452
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.452
2hc4VDXVitamin D3 receptor A/0.452
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.452
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3bheBZNGag-Pol polyprotein3.4.23.160.452
3c4zADPRhodopsin kinase/0.452
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3gu6ADPDeath-associated protein kinase 12.7.11.10.452
3zptM8YGag-Pol polyprotein3.4.23.160.452
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.452
1me8RVPInosine-5'-monophosphate dehydrogenase/0.451
1oitHDTCyclin-dependent kinase 22.7.11.220.451
1x8b824Wee1-like protein kinase2.7.10.20.451
2ijmADPFocal adhesion kinase 12.7.10.20.451
2z2w770Wee1-like protein kinase2.7.10.20.451
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
4acm7YGCyclin-dependent kinase 22.7.11.220.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.451
1m2pHNACasein kinase II subunit alpha2.7.11.10.450
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.450
3lfsA07Cyclin-dependent kinase 22.7.11.220.450
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.450
4ix6ADPUncharacterized protein/0.450
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.450
4qmzB49Serine/threonine-protein kinase 242.7.11.10.450
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.450
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.450
5av4GENDeath-associated protein kinase 12.7.11.10.450
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.449
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.449
2xb7GUIALK tyrosine kinase receptor2.7.10.10.449
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.449
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.449
3qzhX69Cyclin-dependent kinase 22.7.11.220.449
4aqc88ATyrosine-protein kinase JAK2/0.449
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.449
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.449
1qmzATPCyclin-dependent kinase 22.7.11.220.448
2a4lRRCCyclin-dependent kinase 22.7.11.220.448
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.448
2btrU73Cyclin-dependent kinase 22.7.11.220.448
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
2p33J07Mitogen-activated protein kinase 102.7.11.240.448
3cgfJNFMitogen-activated protein kinase 102.7.11.240.448
3ormAGSSerine/threonine protein kinase/0.448
3ttiKBIMitogen-activated protein kinase 102.7.11.240.448
4b8lA0PAurora kinase B-A2.7.11.10.448
4fv8E63Mitogen-activated protein kinase 12.7.11.240.448
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
1nzdUPGDNA beta-glucosyltransferase/0.447
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.447
2c4g514Cyclin-dependent kinase 22.7.11.220.447
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.447
2yaaATPDeath-associated protein kinase 2/0.447
2yn8STUEphrin type-B receptor 42.7.10.10.447
3c4xATPRhodopsin kinase/0.447
3eyhIZATyrosine-protein kinase JAK1/0.447
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.447
3w33W19Epidermal growth factor receptor2.7.10.10.447
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.447
4eomATPCyclin-dependent kinase 22.7.11.220.447
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.447
4k9yK9YFocal adhesion kinase 12.7.10.20.447
4qnaX11Serine/threonine-protein kinase 242.7.11.10.447
1e9hINRCyclin-dependent kinase 22.7.11.220.446
3dfcANPDeath-associated protein kinase 12.7.11.10.446
3nynSGVG protein-coupled receptor kinase 62.7.11.160.446
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.446
4fkv61KCyclin-dependent kinase 22.7.11.220.446
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.446
4iteTEYVitamin D3 receptor/0.446
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.446
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.446
4y93746Tyrosine-protein kinase/0.446
1oiyN41Cyclin-dependent kinase 22.7.11.220.445
1pkdUCNCyclin-dependent kinase 22.7.11.220.445
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.445
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.445
3uyt0CKCasein kinase I isoform delta2.7.11.10.445
3uzp0CKCasein kinase I isoform delta2.7.11.10.445
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.445
4fmqANPMitogen-activated protein kinase 12.7.11.240.445
4hge15VTyrosine-protein kinase JAK2/0.445
4ivb1J5Tyrosine-protein kinase JAK1/0.445
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.445
4yuqKS1Calmodulin-like domain protein kinase/0.445
1k6tXN1Gag-Pol polyprotein3.4.23.160.444
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.444
2a0cCK9Cyclin-dependent kinase 22.7.11.220.444
2qo9ANPEphrin type-A receptor 32.7.10.10.444
3rak03ZCyclin-dependent kinase 22.7.11.220.444
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4c61LMMTyrosine-protein kinase JAK2/0.444
4ek816KCyclin-dependent kinase 22.7.11.220.444
4g3pUD1Bifunctional protein GlmU/0.444
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.444
1fvv107Cyclin-dependent kinase 22.7.11.220.443
2hamC33Vitamin D3 receptor/0.443
2iw84SPCyclin-dependent kinase 22.7.11.220.443
2pwrG4GGag-Pol polyprotein3.4.23.160.443
2pywADPMethylthioribose kinase2.7.1.1000.443
4fhi0S4Vitamin D3 receptor A/0.443
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.443
4gu94GUFocal adhesion kinase 12.7.10.20.443
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.443
4jq8KJ8Epidermal growth factor receptor2.7.10.10.443
5cshATPCasein kinase II subunit alpha2.7.11.10.443
5cvhADPCasein kinase II subunit alpha2.7.11.10.443
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1tvoFRZMitogen-activated protein kinase 12.7.11.240.442
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.442
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.442
2j0j4STFocal adhesion kinase 12.7.10.20.442
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.442
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.442
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.442
3ttjJBIMitogen-activated protein kinase 102.7.11.240.442
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.442
4ez50RSCyclin-dependent kinase 62.7.11.220.442
4fkw62KCyclin-dependent kinase 22.7.11.220.442
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.442
4ic7ANPMitogen-activated protein kinase 72.7.11.240.442
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.442
1wvySTUDeath-associated protein kinase 12.7.11.10.441
2b7aIZATyrosine-protein kinase JAK2/0.441
2qnqQN3Gag-Pol polyprotein3.4.23.160.441
2wouZZFTGF-beta receptor type-12.7.11.300.441
3rpv26ZCyclin-dependent kinase 22.7.11.220.441
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.441
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4hjoAQ4Epidermal growth factor receptor2.7.10.10.441
5av3KMPDeath-associated protein kinase 12.7.11.10.441
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1g5sI17Cyclin-dependent kinase 22.7.11.220.440
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.440
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2ftoCB3Thymidylate synthase/0.440
2izt23DCasein kinase I isoform gamma-32.7.11.10.440
2j0k4STFocal adhesion kinase 12.7.10.20.440
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.440
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.440
2zjwREFCasein kinase II subunit alpha2.7.11.10.440
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.440
3rvg17PTyrosine-protein kinase JAK2/0.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
3vt45YIVitamin D3 receptor/0.440
3zewSTUEphrin type-B receptor 42.7.10.10.440
4ek610KCyclin-dependent kinase 22.7.11.220.440
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fkpLS5Cyclin-dependent kinase 22.7.11.220.440
4ienCOAPutative acyl-CoA hydrolase/0.440