sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.829 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.820 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.808 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.805 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.802 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.800 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.785 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.782 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.780 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.777 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.758 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.635 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.620 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.614 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.611 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.601 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.577 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.571 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.562 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.561 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.553 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.553 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.551 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.551 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.548 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.544 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.524 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.521 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.515 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.514 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.512 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.509 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.507 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.507 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.507 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.506 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.503 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.503 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.503 | |
| 4iae | 1DX | Alr2278 protein | / | 0.500 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.498 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.497 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.497 | |
| 4iah | 1DX | Alr2278 protein | / | 0.497 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.494 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.494 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.493 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.491 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.491 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.491 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.491 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.491 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.490 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.489 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.489 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.488 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.485 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.483 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.482 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.482 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.482 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.482 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.482 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.481 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.481 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.480 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.479 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.478 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.477 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.476 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.474 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.473 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.473 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.473 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.472 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.472 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.472 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.472 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.472 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.471 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.470 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.469 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.469 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 4fx9 | COA | Coenzyme A disulfide reductase | 1.8.1.14 | 0.469 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.469 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.469 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.468 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.468 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.468 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.468 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.468 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.467 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.467 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.467 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.467 | |
| 1dtp | APU | Diphtheria toxin | / | 0.466 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.466 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.466 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.465 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.465 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.465 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.464 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.464 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.464 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.464 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.463 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.463 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.463 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.463 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.463 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.463 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.462 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.462 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.462 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.462 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.462 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.461 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.461 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.461 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.461 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.461 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.461 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.461 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.460 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.460 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.460 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.460 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.460 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.459 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.459 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.459 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.459 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.459 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.459 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.459 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.459 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4e2b | FMN | Dehydrogenase | / | 0.459 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.459 | |
| 5cyo | GDP | Septin-9 | / | 0.459 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.458 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.458 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.458 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.457 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.457 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.457 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.457 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.457 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.457 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.457 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.456 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.456 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.455 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.455 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.455 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.455 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.455 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.455 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.455 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.454 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.454 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.454 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.454 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.454 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.454 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.454 | |
| 4boe | CLR | Japanin | / | 0.454 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.454 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.454 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.454 | |
| 4xr9 | NAD | CalS8 | / | 0.454 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.454 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.453 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.453 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1jf2 | CZH | Obelin | / | 0.453 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.453 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.453 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.453 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.453 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.453 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.452 | |
| 1x28 | PGU | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.452 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.452 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.452 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3c1o | NAP | Eugenol synthase | / | 0.451 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.451 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.451 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.450 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.450 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.450 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.450 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.450 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.450 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.450 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.450 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.450 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.450 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.449 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.449 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.449 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.449 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.449 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.449 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.449 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.449 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.448 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.448 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.448 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.448 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.448 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.448 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.448 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.448 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.447 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.447 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 2ejz | SAH | Diphthine synthase | / | 0.447 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.447 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.447 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 4chq | CWU | Integrase | / | 0.447 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.447 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.447 | |
| 4y1b | NAP | AntE | / | 0.447 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.446 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.446 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.445 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.445 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.445 | |
| 4jic | FMN | GTN Reductase | / | 0.445 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.444 | |
| 3arp | DEQ | Chitinase A | / | 0.444 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.444 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3e8x | NAP | BH1520 protein | / | 0.444 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.444 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4e2d | FMN | Dehydrogenase | / | 0.444 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.444 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4n1g | CEI | Obelin | / | 0.444 | |
| 4v12 | POG | MaoC like domain protein | / | 0.444 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.444 | |
| 1c7o | PPG | Hemolysin | / | 0.443 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.443 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.443 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.443 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.443 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.443 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.443 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.442 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.442 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.442 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.442 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.442 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.442 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.442 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.441 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.441 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.441 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 1xa4 | COA | L-carnitine CoA-transferase | / | 0.441 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.441 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.441 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.441 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.441 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.441 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4eqk | MGT | Polymerase basic protein 2 | / | 0.441 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.441 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.441 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.441 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.440 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.440 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.440 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.440 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2b8t | THM | Thymidine kinase | / | 0.440 | |
| 2bxo | OPB | Serum albumin | / | 0.440 | |
| 3a6r | FMN | FMN-binding protein | / | 0.440 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.440 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.440 | |
| 4e32 | DWN | Methyltransferase | / | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.440 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.440 |