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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3f0fC5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3f0fC5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/1.000
3jvhHHV2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.568
3iewCTP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.548
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.491
4bgh3I6Cyclin-dependent kinase 22.7.11.220.489
4fkw62KCyclin-dependent kinase 22.7.11.220.487
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.485
1ke9LS5Cyclin-dependent kinase 22.7.11.220.481
1fvt106Cyclin-dependent kinase 22.7.11.220.479
4eh60ONMitogen-activated protein kinase 14/0.479
2btsU32Cyclin-dependent kinase 22.7.11.220.478
2iviACWIsopenicillin N synthase1.21.3.10.476
2y60M8FIsopenicillin N synthase1.21.3.10.476
3s0o50ZCyclin-dependent kinase 22.7.11.220.475
3zkyWT4Isopenicillin N synthase1.21.3.10.475
2gfdRDAEndoplasmin/0.474
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.474
1dr3HBIDihydrofolate reductase1.5.1.30.473
2byh2D7Heat shock protein HSP 90-alpha/0.473
1ckpPVBCyclin-dependent kinase 22.7.11.220.472
3upjU03Gag-Pol polyprotein/0.472
1w06W05Isopenicillin N synthase1.21.3.10.471
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.471
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.471
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.471
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.470
2bhhRYUCyclin-dependent kinase 22.7.11.220.470
2xvv9DNSerum albumin/0.470
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.470
3p7nFMNLight-activated DNA-binding protein EL222/0.470
4hw764MMacrophage colony-stimulating factor 1 receptor2.7.10.10.470
1d4yTPVGag-Pol polyprotein3.4.23.160.469
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.469
2esaGDMEndoplasmin/0.469
2y9qANPMitogen-activated protein kinase 12.7.11.240.469
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.469
4b1rITCTetracycline repressor protein class D/0.469
2bxmIMNSerum albumin/0.468
2wotZZGTGF-beta receptor type-12.7.11.300.468
1gih1PUCyclin-dependent kinase 22.7.11.220.467
1nsfATPVesicle-fusing ATPase3.6.4.60.467
1oirHDYCyclin-dependent kinase 22.7.11.220.467
2vwqNAPGlucose 1-dehydrogenase/0.467
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.467
2iw84SPCyclin-dependent kinase 22.7.11.220.466
2z6dFMNPhototropin-22.7.11.10.466
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.466
1hvlA76Gag-Pol polyprotein/0.465
2bu8ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.465
1g4tFTPThiamine-phosphate synthase/0.464
1h1r6CPCyclin-dependent kinase 22.7.11.220.464
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.464
1q1wFADPutidaredoxin reductase1.18.1.50.464
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.464
1b39ATPCyclin-dependent kinase 22.7.11.220.463
1bk0ACVIsopenicillin N synthase1.21.3.10.463
1hb1OCVIsopenicillin N synthase1.21.3.10.463
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.463
1vjy460TGF-beta receptor type-12.7.11.300.463
2aznNAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase/0.463
2hckQUETyrosine-protein kinase HCK2.7.10.20.463
2q631UNGag-Pol polyprotein3.4.23.160.463
3d4pNADL-lactate dehydrogenase 11.1.1.270.463
3el1DR7Gag-Pol polyprotein3.4.23.160.463
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.463
1hb3SCVIsopenicillin N synthase1.21.3.10.462
1jpaANPEphrin type-B receptor 22.7.10.10.462
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.462
1qvrANPChaperone protein ClpB/0.462
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.462
2r64740Cyclin-dependent kinase 22.7.11.220.462
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.462
4e4l0NHTyrosine-protein kinase JAK1/0.462
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.462
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.462
1g67TZPThiamine-phosphate synthase/0.461
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1uzwCDHIsopenicillin N synthase1.21.3.10.461
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.461
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.461
4asg814ATP-dependent molecular chaperone HSP82/0.461
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.461
4g95OAGDihydrofolate reductase1.5.1.30.461
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.461
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.460
2fypRDEEndoplasmin/0.460
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.460
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
3nu3478Gag-Pol polyprotein3.4.23.160.460
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.460
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.460
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.460
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.460
4ez30S0Cyclin-dependent kinase 22.7.11.220.460
1gij2PUCyclin-dependent kinase 22.7.11.220.459
1pkdUCNCyclin-dependent kinase 22.7.11.220.459
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.459
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.459
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.459
2qd8065Gag-Pol polyprotein3.4.23.160.459
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.459
2wouZZFTGF-beta receptor type-12.7.11.300.459
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.459
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.459
4upjU04Gag-Pol polyprotein/0.459
6cp4CAMCamphor 5-monooxygenase1.14.15.10.459
1b6pPI7Gag-Pol polyprotein3.4.23.160.458
1dr3TAPDihydrofolate reductase1.5.1.30.458
1nb9RBFRiboflavin kinase2.7.1.260.458
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.458
3kfr3TLGag-Pol polyprotein/0.458
4fv9E71Mitogen-activated protein kinase 12.7.11.240.458
4hnbFMNLOV protein/0.458
4ivc1J6Tyrosine-protein kinase JAK1/0.458
4riyADPEpidermal growth factor receptor2.7.10.10.458
4u0mGTPCyclic GMP-AMP synthase/0.458
9hvp0E9Gag-Pol polyprotein/0.458
1bdqIM1Gag-Pol polyprotein3.4.23.160.457
1fnnADPORC1-type DNA replication protein/0.457
1hvkA79Gag-Pol polyprotein/0.457
2vwx7X4Ephrin type-B receptor 42.7.10.10.457
3ekwDR7Gag-Pol polyprotein3.4.23.160.457
3ogqAB1Pol polyprotein/0.457
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.457
1b6lPI4Gag-Pol polyprotein3.4.23.160.456
1w0xOLOCyclin-dependent kinase 22.7.11.220.456
1zrzBI1Protein kinase C iota type2.7.11.130.456
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.456
2f8g017Gag-Pol polyprotein3.4.23.160.456
2hk9NAPShikimate dehydrogenase (NADP(+))/0.456
3nxe2NCProtease/0.456
3sheI85MAP kinase-activated protein kinase 32.7.11.10.456
4b1vLABActin, alpha skeletal muscle/0.456
4fkpLS5Cyclin-dependent kinase 22.7.11.220.456
4gk2L66Ephrin type-A receptor 32.7.10.10.456
1dr2TAPDihydrofolate reductase1.5.1.30.455
1meiMOAInosine-5'-monophosphate dehydrogenase/0.455
1w8cN69Cyclin-dependent kinase 22.7.11.220.455
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.455
2duv371Cyclin-dependent kinase 22.7.11.220.455
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.455
4eor4SPCyclin-dependent kinase 22.7.11.220.455
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.455
4fx360KCyclin-dependent kinase 22.7.11.220.455
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.455
4prxADPDNA gyrase subunit B/0.455
4r3aRBFBlue-light-activated histidine kinase 22.7.13.30.455
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.455
1oi9N20Cyclin-dependent kinase 22.7.11.220.454
1y4lSVRBasic phospholipase A2 homolog 2/0.454
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.454
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3pj8404Cyclin-dependent kinase 22.7.11.220.454
3qqkX02Cyclin-dependent kinase 22.7.11.220.454
3qu0X40Cyclin-dependent kinase 22.7.11.220.454
3zh8C58Protein kinase C iota type2.7.11.130.454
3zoiM2WIsopenicillin N synthase1.21.3.10.454
4affATPNitrogen regulatory protein P-II/0.454
1d4kPI8Gag-Pol polyprotein3.4.23.160.453
1g6cIFPThiamine-phosphate synthase/0.453
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.453
1ke5LS1Cyclin-dependent kinase 22.7.11.220.453
1mesDMPGag-Pol polyprotein3.4.23.160.453
1py5PY1TGF-beta receptor type-12.7.11.300.453
1pyePM1Cyclin-dependent kinase 22.7.11.220.453
2bb9AKCGag-Pol polyprotein3.4.23.160.453
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.453
2izt23DCasein kinase I isoform gamma-32.7.11.10.453
2xd6XD6ATP-dependent molecular chaperone HSP82/0.453
3ijwACOAminoglycoside N3-acetyltransferase/0.453
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.453
3rpv26ZCyclin-dependent kinase 22.7.11.220.453
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4c57FEFCyclin-G-associated kinase2.7.11.10.453
4i22IREEpidermal growth factor receptor2.7.10.10.453
1me8RVPInosine-5'-monophosphate dehydrogenase/0.452
2b55D31Cyclin-dependent kinase 22.7.11.220.452
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.452
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.452
2hog710Serine/threonine-protein kinase Chk12.7.11.10.452
2hs2017Protease/0.452
2pr5FMNBlue-light photoreceptor/0.452
3d1xROCGag-Pol polyprotein3.4.23.160.452
3dogNNNCyclin-dependent kinase 22.7.11.220.452
3gqoAPRNon-structural polyprotein/0.452
3iggEFQCyclin-dependent kinase 22.7.11.220.452
3mxdK53Gag-Pol polyprotein3.4.23.160.452
3ral04ZCyclin-dependent kinase 22.7.11.220.452
4b7p9UNHeat shock protein HSP 90-alpha/0.452
4c58824Cyclin-G-associated kinase2.7.11.10.452
4hdpG52Gag-Pol polyprotein3.4.23.160.452
4hj6FMNLOV protein/0.452
4ipeANPTNF receptor-associated protein 1/0.452
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4xc0ACPHeat shock cognate 90 kDa protein/0.452
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
1gii1PUCyclin-dependent kinase 22.7.11.220.451
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1rx8NAPDihydrofolate reductase1.5.1.30.451
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.451
2fxsRDAATP-dependent molecular chaperone HSP82/0.451
2iorADPChaperone protein HtpG/0.451
2jd1NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.451
2nnpROCProtease/0.451
3ql8X01Cyclin-dependent kinase 22.7.11.220.451
3u2mFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.451
3ue6FMNAureochrome1/0.451
3uvvREARetinoic acid receptor RXR-alpha/0.451
3wd7COAAcridone synthase/0.451
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.451
4a6nFADTetX family tetracycline inactivation enzyme/0.451
4fkv61KCyclin-dependent kinase 22.7.11.220.451
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.451
1dm2HMDCyclin-dependent kinase 22.7.11.220.450
1drhNAPDihydrofolate reductase1.5.1.30.450
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1qbsDMPGag-Pol polyprotein3.4.23.160.450
1qxlFR8Adenosine deaminase3.5.4.40.450
1rx1NAPDihydrofolate reductase1.5.1.30.450
1sduMK1Gag-Pol polyprotein3.4.23.160.450
1u3dFADCryptochrome-1/0.450
2cig1DGDihydrofolate reductase1.5.1.30.450
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.450
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.450
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.450
2o7pNAPRiboflavin biosynthesis protein RibD/0.450
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
2znnS44Peroxisome proliferator-activated receptor alpha/0.450
3ecg065Gag-Pol polyprotein3.4.23.470.450
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.450
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.450
3qlrNDPDihydrofolate reductase1.5.1.30.450
3rni21ZCyclin-dependent kinase 22.7.11.220.450
3tl9ROCGag-Pol polyprotein3.4.23.160.450
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.450
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.450
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.450
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.450
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.450
1fm8DDCChalcone--flavonone isomerase 15.5.1.60.449
1g69TZPThiamine-phosphate synthase/0.449
1ivq0PXGag-Pol polyprotein/0.449
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.449
1rbyGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.449
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
2r3r6SCCyclin-dependent kinase 22.7.11.220.449
2uzoC62Cyclin-dependent kinase 22.7.11.220.449
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.449
3ekyDR7Gag-Pol polyprotein3.4.23.160.449
3juqAJDPhenazine biosynthesis protein A/B/0.449
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.449
3lsiFADPyranose 2-oxidase/0.449
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.449
3qrmNK7Gag-Pol polyprotein3.4.23.160.449
3qyw6PBMitogen-activated protein kinase 12.7.11.240.449
3roy22ZCyclin-dependent kinase 22.7.11.220.449
3rpr25ZCyclin-dependent kinase 22.7.11.220.449
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.449
3unk0BYCyclin-dependent kinase 22.7.11.220.449
4eok4SPCyclin-dependent kinase 22.7.11.220.449
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.449
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4hjfC2EGGDEF family protein/0.449
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.449
4wucANPDNA gyrase subunit B/0.449
5hidB1ESerine/threonine-protein kinase B-raf2.7.11.10.449
1mvsDTMDihydrofolate reductase1.5.1.30.448
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.448
1uymPU3Heat shock protein HSP 90-beta/0.448
1xddAAYIntegrin alpha-L/0.448
2cppCAMCamphor 5-monooxygenase1.14.15.10.448
2uzlC94Cyclin-dependent kinase 22.7.11.220.448
3cic316Beta-secretase 13.4.23.460.448
3ec0GRLGag-Pol polyprotein3.4.23.470.448
3qzgX67Cyclin-dependent kinase 22.7.11.220.448
3zmmF9JTyrosine-protein kinase JAK2/0.448
4aa5NQBMitogen-activated protein kinase 14/0.448
4c02TAKActivin receptor type-12.7.11.300.448
4e37NDPCatalase1.11.1.60.448
4erwSTUCyclin-dependent kinase 22.7.11.220.448
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.448
5kj6PFBAlcohol dehydrogenase E chain1.1.1.10.448
1ec3MS3Gag-Pol polyprotein3.4.23.160.447
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.447
1ke6LS2Cyclin-dependent kinase 22.7.11.220.447
1oguST8Cyclin-dependent kinase 22.7.11.220.447
1qf5RPLAdenylosuccinate synthetase/0.447
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.447
1v59NADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.447
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.447
2o1uANPEndoplasmin/0.447
2r3lSCWCyclin-dependent kinase 22.7.11.220.447
2vwy7X5Ephrin type-B receptor 42.7.10.10.447
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.447
3mvl38PMitogen-activated protein kinase 14/0.447
3pwrROCGag-Pol polyprotein3.4.23.160.447
3r8vZ62Cyclin-dependent kinase 22.7.11.220.447
3sw719KCyclin-dependent kinase 22.7.11.220.447
4b99R4LMitogen-activated protein kinase 72.7.11.240.447
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.447
4c4f7CEDual specificity protein kinase TTK2.7.12.10.447
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.447
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
4j361HRKynurenine 3-monooxygenase/0.447
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
1bv9XV6Gag-Pol polyprotein3.4.23.160.446
1db1VDXVitamin D3 receptor/0.446
1dmpDMQGag-Pol polyprotein3.4.23.160.446
1fwkADPHomoserine kinase2.7.1.390.446
1h1pCMGCyclin-dependent kinase 22.7.11.220.446
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.446
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.446
1sbgIM1Gag-Pol polyprotein/0.446
1xe65FPPlasmepsin-23.4.23.390.446
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.446
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.446
3b895GP16S rRNA methylase/0.446
3b9lAZZSerum albumin/0.446
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3ctyFADProbable thioredoxin reductase/0.446
3ggfGVDSerine/threonine-protein kinase 26/0.446
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.446
3r9nZ68Cyclin-dependent kinase 22.7.11.220.446
3rvg17PTyrosine-protein kinase JAK2/0.446
3s2pPMUCyclin-dependent kinase 22.7.11.220.446
3sqq99ZCyclin-dependent kinase 22.7.11.220.446
3sw1FMNSensory box protein/0.446
3uyt0CKCasein kinase I isoform delta2.7.11.10.446
3v9v21LPeroxisome proliferator-activated receptor gamma/0.446
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.446
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.446
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.446
4lb2DM5Serum albumin/0.446
4qmpDKISerine/threonine-protein kinase 242.7.11.10.446
1ke8LS4Cyclin-dependent kinase 22.7.11.220.445
1p2a5BNCyclin-dependent kinase 22.7.11.220.445
1z1rHBHGag-Pol polyprotein3.4.23.160.445
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.445
2hc0AB2Protease/0.445
2pvnP63Casein kinase II subunit alpha2.7.11.10.445
2pwrG4GGag-Pol polyprotein3.4.23.160.445
2q54MU1Protease/0.445
2whdFADThioredoxin reductase/0.445
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.445
2xa4AZ5Tyrosine-protein kinase JAK2/0.445
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.445
3a62STURibosomal protein S6 kinase beta-12.7.11.10.445
3dd125DGlycogen phosphorylase, liver form2.4.1.10.445
3ekv478Gag-Pol polyprotein3.4.23.160.445
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3iewCDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.445
3kf03TLGag-Pol polyprotein/0.445
3oxxDR7Gag-Pol polyprotein3.4.23.160.445
3pe6ZYHMonoglyceride lipase/0.445
3rmf20ZCyclin-dependent kinase 22.7.11.220.445
3s54017Protease/0.445
4fv7E94Mitogen-activated protein kinase 12.7.11.240.445
4ivb1J5Tyrosine-protein kinase JAK1/0.445
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.445
1daz0Q4Gag-Pol polyprotein3.4.23.160.444
1meiXMPInosine-5'-monophosphate dehydrogenase/0.444
1v1k3FPCyclin-dependent kinase 22.7.11.220.444
1w4xFADPhenylacetone monooxygenase1.14.13.920.444
1yrdCAMCamphor 5-monooxygenase1.14.15.10.444
1zsr0ZTGag-Pol polyprotein3.4.23.160.444
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.444
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.444
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.444
2y05NAPProstaglandin reductase 1/0.444
2yefANPHeat shock protein HSP 90-alpha/0.444
2znpK55Peroxisome proliferator-activated receptor delta/0.444
3bxsDRSGag-Pol polyprotein3.4.23.160.444
3ekx1UNGag-Pol polyprotein3.4.23.160.444
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.444
3r6xX84Cyclin-dependent kinase 22.7.11.220.444
3sm2478Putative gag-pro-pol polyprotein/0.444
3uli1N3Cyclin-dependent kinase 22.7.11.220.444
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.444
4ek610KCyclin-dependent kinase 22.7.11.220.444
4gqtADPHeat shock protein 90/0.444
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.444
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.444
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.444
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.443
1bdlIM1Gag-Pol polyprotein3.4.23.160.443
1eh4IC1Casein kinase I homolog 12.7.11.10.443
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1f123HCHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1hvrXK2Gag-Pol polyprotein/0.443
1k2c0Q4Gag-Pol polyprotein3.4.23.160.443
2of4979Tyrosine-protein kinase Lck2.7.10.20.443
2qci065Gag-Pol polyprotein3.4.23.160.443
2v52LABActin, alpha skeletal muscle/0.443
3ddqRRCCyclin-dependent kinase 22.7.11.220.443
3gxlQIGTGF-beta receptor type-12.7.11.300.443
3hx4ANPCalmodulin-domain protein kinase 1/0.443
3kenZZDKinesin-like protein KIF11/0.443
3ndxRITGag-Pol polyprotein3.4.23.160.443
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.443
3qx4X4BCyclin-dependent kinase 22.7.11.220.443
3rdqDTBStreptavidin/0.443
3rk708ZCyclin-dependent kinase 22.7.11.220.443
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4ek1CAMCamphor 5-monooxygenase1.14.15.10.443
4ji91M3Tyrosine-protein kinase JAK2/0.443
4z34ON7Lysophosphatidic acid receptor 1/0.443
1bdrIM1Gag-Pol polyprotein3.4.23.160.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1jld0PPGag-Pol polyprotein/0.442
1kvkATPMevalonate kinase2.7.1.360.442
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.442
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.442
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.442
1u2oNECEndoplasmin/0.442
1wbmBLLPol protein/0.442
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.442
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.442
2r5pMK1Gag-Pol polyprotein/0.442
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.442
2xx213CATP-dependent molecular chaperone HSP82/0.442
3d7kD7KBenzaldehyde lyase/0.442
3el4ROCGag-Pol polyprotein3.4.23.160.442
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.442
3ndtROCGag-Pol polyprotein3.4.23.160.442
3rm618ZCyclin-dependent kinase 22.7.11.220.442
3s00Z60Cyclin-dependent kinase 22.7.11.220.442
3sw418KCyclin-dependent kinase 22.7.11.220.442
3t50FMNBlue-light-activated histidine kinase2.7.13.30.442
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
4ce17FKATP-dependent molecular chaperone HSP82/0.442
4ei40Q2Tyrosine-protein kinase JAK1/0.442
4fko20KCyclin-dependent kinase 22.7.11.220.442
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.442
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.442
5cvhADPCasein kinase II subunit alpha2.7.11.10.442
5drdATPAurora kinase A2.7.11.10.442
6upjNIUGag-Pol polyprotein/0.442
1bgqRDCATP-dependent molecular chaperone HSP82/0.441
1c6zROCProtease/0.441
1hwr216Gag-Pol polyprotein3.4.23.160.441
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.441
1n9nFMNPutative blue light receptor/0.441
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1xkkFMMEpidermal growth factor receptor2.7.10.10.441
1zys199Serine/threonine-protein kinase Chk12.7.11.10.441
2avsMK1Gag-Pol polyprotein3.4.23.160.441
2excJNKMitogen-activated protein kinase 102.7.11.240.441
2huvSAHDiphthine synthase/0.441
2izuP01Casein kinase I isoform gamma-32.7.11.10.441
2r3o2SCCyclin-dependent kinase 22.7.11.220.441
2rc6NAPFerredoxin--NADP reductase/0.441
2xk2ADPHeat shock protein HSP 90-alpha/0.441
2yeiXQIHeat shock protein HSP 90-alpha/0.441
2zb3NDPProstaglandin reductase 21.3.1.480.441
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3zpsEQMGag-Pol polyprotein3.4.23.160.441
4aa4QC0Mitogen-activated protein kinase 14/0.441
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4e8wIHAD-beta-D-heptose 7-phosphate kinase/0.441
4enhFVXCholesterol 24-hydroxylase/0.441
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.441
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
4nmbFADBifunctional protein PutA/0.441
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.441
4wa9AXITyrosine-protein kinase ABL12.7.10.20.441
5e92ANPTGF-beta receptor type-22.7.11.300.441
1blzACVIsopenicillin N synthase1.21.3.10.440
1c2tNHSPhosphoribosylglycinamide formyltransferase/0.440
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.440
1ebzBECGag-Pol polyprotein3.4.23.160.440
1eyqNARChalcone--flavonone isomerase 15.5.1.60.440
1npa3NHGag-Pol polyprotein3.4.23.160.440
1npwLGZGag-Pol polyprotein3.4.23.160.440
1qvnFRIInterleukin-2/0.440
1rw8580TGF-beta receptor type-12.7.11.300.440
1unhIXMCyclin-dependent-like kinase 52.7.11.10.440
1uyuCAMCamphor 5-monooxygenase1.14.15.10.440
1z1hHBBGag-Pol polyprotein3.4.23.160.440
2aquDR7Gag-Pol polyprotein3.4.23.160.440
2f80017Gag-Pol polyprotein3.4.23.160.440
2gj3FADNitrogen fixation regulatory protein2.7.13.30.440
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2p6lSAHDiphthine synthase/0.440
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.440
3b7kCOAAcyl-coenzyme A thioesterase 123.1.2.10.440
3bv3P39Mitogen-activated protein kinase 14/0.440
3cvuFADRE11660p/0.440
3cyxROCGag-Pol polyprotein3.4.23.160.440
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.440
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.440
3gi4K60Gag-Pol polyprotein/0.440
3lovFADProtoporphyrinogen oxidase/0.440
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3p5kP5KMitogen-activated protein kinase 14/0.440
3r8lZ30Cyclin-dependent kinase 22.7.11.220.440
3s1dZIRCytokinin dehydrogenase 11.5.99.120.440
3vydVYDRenin3.4.23.150.440
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.440
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.440
3zsi52PMitogen-activated protein kinase 14/0.440
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.440
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.440
4fmqANPMitogen-activated protein kinase 12.7.11.240.440
4fob0USALK tyrosine kinase receptor2.7.10.10.440
4rvj478Protease/0.440
5e8ySTUTGF-beta receptor type-22.7.11.300.440