sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dgq | EAA | Glutathione S-transferase P | 2.5.1.18 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3dgq | EAA | Glutathione S-transferase P | 2.5.1.18 | 1.000 | |
| 3n9j | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.657 | |
| 1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.653 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.640 | |
| 3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.615 | |
| 3csj | CBL | Glutathione S-transferase P | 2.5.1.18 | 0.610 | |
| 20gs | CBD | Glutathione S-transferase P | 2.5.1.18 | 0.608 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.604 | |
| 9gss | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.596 | |
| 1aqx | GTD | Glutathione S-transferase P | 2.5.1.18 | 0.590 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.586 | |
| 1pgt | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.585 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.582 | |
| 2glr | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.580 | |
| 2oac | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.578 | |
| 2oa7 | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.576 | |
| 2j9h | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.556 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.555 | |
| 3pgt | GBX | Glutathione S-transferase P | 2.5.1.18 | 0.555 | |
| 12gs | 0HH | Glutathione S-transferase P | 2.5.1.18 | 0.550 | |
| 2oad | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.546 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.514 | |
| 1mtc | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.509 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.508 | |
| 2po3 | T4K | 4-dehydrase | / | 0.506 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.506 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.506 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.505 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.501 | |
| 4n1g | CEI | Obelin | / | 0.500 | |
| 1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.499 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.499 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.498 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.495 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.494 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.494 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.491 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.491 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.491 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.490 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.489 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.488 | |
| 2xvw | 9NR | Serum albumin | / | 0.487 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.484 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.483 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.482 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.482 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.482 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.482 | |
| 3b9l | AZZ | Serum albumin | / | 0.481 | |
| 3pfh | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.481 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.481 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.481 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.481 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.480 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.480 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.480 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.479 | |
| 2r4u | ADP | Glycogen synthase | 2.4.1.21 | 0.479 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.479 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.479 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.478 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.478 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.478 | |
| 2xvv | 9DN | Serum albumin | / | 0.477 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.477 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.476 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.476 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.476 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.475 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.475 | |
| 3gx9 | TXD | Morphinone reductase | / | 0.475 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.475 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.474 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.474 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.474 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.473 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.472 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.472 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.472 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.472 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.472 | |
| 5kj1 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.472 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.471 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 0.471 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.471 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.471 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.471 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.471 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.470 | |
| 4iah | 1DX | Alr2278 protein | / | 0.470 | |
| 4pu2 | PLU | Aminopeptidase N | / | 0.470 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.470 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.469 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.469 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.469 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.469 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.469 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.469 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.469 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2bxm | IMN | Serum albumin | / | 0.468 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.468 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.468 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.468 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.468 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.468 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.468 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.467 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.467 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.467 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.467 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.467 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.466 | |
| 2r5n | TPP | Transketolase 1 | / | 0.466 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.466 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.466 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.466 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.465 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 3c1o | NAP | Eugenol synthase | / | 0.465 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.465 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.465 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.464 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.464 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.464 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.464 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.464 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.464 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.463 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.463 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.463 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.463 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.463 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.463 | |
| 3eq6 | BCO | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.463 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.463 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.463 | |
| 4iae | 1DX | Alr2278 protein | / | 0.463 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.463 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.462 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 2bxq | IMN | Serum albumin | / | 0.462 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.462 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.462 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.462 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.462 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.462 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.462 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.462 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.461 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.461 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.461 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.461 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.461 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.461 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.461 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.460 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1e2n | RCA | Thymidine kinase | / | 0.460 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.460 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.460 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.460 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.460 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.460 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.459 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.459 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.459 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.459 | |
| 3eku | CY9 | Actin-5C | / | 0.459 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.459 | |
| 3oq6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.459 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.459 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 5kje | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.458 | |
| 1go2 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 1uhh | CZP | Aequorin-2 | / | 0.458 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.458 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.458 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.458 | |
| 3px2 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.458 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.458 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.458 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.458 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 1swg | BTN | Streptavidin | / | 0.457 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.457 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.457 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.457 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.457 | |
| 4dwv | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.457 | |
| 4l4x | NDP | AmphI | / | 0.457 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4nvk | 2NY | Peroxidase | / | 0.457 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.457 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1gul | GLY_GGL_ICY | Glutathione S-transferase A4 | 2.5.1.18 | 0.456 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.456 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.456 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.456 | |
| 2r8p | T6F | Transketolase 1 | / | 0.456 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.456 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.456 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.456 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.456 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.456 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.456 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.455 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.455 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.455 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.455 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.455 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.455 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.455 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.455 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.454 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.454 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.454 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.454 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.454 | |
| 3f90 | FMN | Flavodoxin | / | 0.454 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3sff | 0DI | Histone deacetylase 8 | 3.5.1.98 | 0.454 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.454 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.454 | |
| 4ovi | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.454 | |
| 4typ | AP5 | Adenylate kinase | / | 0.454 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 5ief | NBV | Neutral alpha-glucosidase AB | 3.2.1.84 | 0.454 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.454 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.454 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.453 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.453 | |
| 2iml | FMN | Uncharacterized protein | / | 0.453 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.453 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.453 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3o3r | NAP | Aldose reductase-related protein 1 | 1.1.1.21 | 0.453 | |
| 3sma | ACO | FrbF | / | 0.453 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.453 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.452 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.452 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.452 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.452 | |
| 2r2g | EMF | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.452 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3bt9 | DEQ | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.452 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.452 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.452 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.452 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.452 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.452 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.451 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.451 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.451 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.451 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.451 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.451 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3eks | CY9 | Actin-5C | / | 0.451 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.451 | |
| 3v2u | ATP | Protein GAL3 | / | 0.451 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.451 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.451 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.451 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.451 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.450 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.450 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.450 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.450 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.450 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.450 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.450 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.450 | |
| 4e32 | DWN | Methyltransferase | / | 0.450 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.450 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.450 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.449 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.449 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.449 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.449 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.449 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.449 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.449 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.449 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.449 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.449 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.449 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.449 | |
| 4hxy | NDP | Plm1 | / | 0.449 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.449 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1e79 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.448 | |
| 1e79 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.448 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2e77 | FMN | Lactate oxidase | / | 0.448 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.448 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.448 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.448 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.448 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.448 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.448 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.448 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.448 | |
| 4was | COO | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.448 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1hzz | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.447 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1ndi | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 1u3v | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.447 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.447 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.447 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.447 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.447 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.447 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 4e2d | FMN | Dehydrogenase | / | 0.447 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.447 | |
| 4j7g | TRH | PCZA361.3 | / | 0.447 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.447 | |
| 5cds | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.447 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.446 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.446 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.446 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.446 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.446 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.446 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.446 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.446 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.446 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.446 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.446 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.446 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.446 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.446 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.446 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 4odo | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.446 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.446 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.446 | |
| 5kj6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1efa | NPF | Lactose operon repressor | / | 0.445 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.445 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.445 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2b8t | THM | Thymidine kinase | / | 0.445 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.445 | |
| 2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.445 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2gcq | DOI | Adenylosuccinate synthetase | / | 0.445 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.445 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.445 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.445 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.445 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.445 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.445 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1z1f | STL | Resveratrol synthase | / | 0.444 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.444 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3e6e | DCS | Alanine racemase | / | 0.444 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.444 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.444 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.444 | |
| 3uwk | 0DF | Thymidylate kinase | 2.7.4.9 | 0.444 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.444 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4e2x | TYD | Methyltransferase | / | 0.444 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.444 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4mzu | COA | WxcM-like protein | / | 0.444 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.444 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.444 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.443 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 1p4a | PCP | Pur operon repressor | / | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.443 | |
| 2nm2 | NEU | Dihydroneopterin aldolase | / | 0.443 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.443 | |
| 2qjp | ANJ | Cytochrome b | / | 0.443 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.443 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.443 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.443 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.443 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.443 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.443 | |
| 4a5l | NDP | Thioredoxin reductase | / | 0.443 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.443 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.443 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.443 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.443 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.443 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.442 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.442 | |
| 1jf0 | CZH | Obelin | / | 0.442 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.442 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.442 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.442 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.442 | |
| 2pcg | SAH | Diphthine synthase | / | 0.442 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.442 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.442 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.442 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.442 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4adc | PLP | Succinylornithine transaminase | 2.6.1.81 | 0.442 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.442 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.442 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.442 | |
| 6adh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.442 | |
| 3ny9 | JSZ | Beta-2 adrenergic receptor | / | 0.442 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.441 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.441 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.441 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.441 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.441 | |
| 3jsz | UPG | Uncharacterized protein | / | 0.441 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 3wag | TYD | Glycosyltransferase | / | 0.441 | |
| 3wb5 | 0B4 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.441 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.440 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.440 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2wq6 | FAD | RE11660p | / | 0.440 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3mje | NDP | AmphB | / | 0.440 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4dwv | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.440 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.440 |