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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2bmeGNPRas-related protein Rab-4A

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2bmeGNPRas-related protein Rab-4A/1.000
1yu9GNPRas-related protein Rab-4A/0.623
4lrwGDPGTPase KRas/0.602
4ql3GDPGTPase KRas/0.597
1n6lGTPRas-related protein Rab-5A/0.596
4q03GDPGTPase KRas/0.596
4obeGDPGTPase KRas/0.595
3tgpGNPGTPase HRas/0.589
2fg5GNPRas-related protein Rab-31/0.585
2rggGNPGTPase HRas/0.579
4tq9GDPGTPase KRas/0.579
4epxGDPGTPase KRas/0.575
2fe4GDPRas-related protein Rab-6B/0.574
4l9sGDPGTPase HRas/0.574
3kkoGNPRas-related protein M-Ras/0.572
4lpkGDPGTPase KRas/0.571
2p2lGDPRas-related C3 botulinum toxin substrate 1/0.564
4q02GDPGTPase KRas/0.564
4l8gGDPGTPase KRas/0.560
4ldjGDPGTPase KRas/0.559
4lv6GDPGTPase KRas/0.559
4epwGDPGTPase KRas/0.558
4uj5GNPRas-related protein Rab-11A/0.557
3cphGDPRas-related protein SEC4/0.556
4o2rGDPGTP-binding protein Rheb/0.556
4qxaGTPRas-related protein Rab-9A/0.556
3qbtGNPRas-related protein Rab-8A/0.555
3pitGNPRas-related protein M-Ras/0.553
1x1rGDPRas-related protein M-Ras/0.552
3ddcGNPGTPase HRas/0.551
4xvqGNPGTPase HRas/0.551
4lhwGNPRas-related protein Rab-8A/0.549
2q3fGNPRas-related GTP-binding protein D/0.548
3kkqGDPRas-related protein M-Ras/0.545
4uj3GNPRas-related protein Rab-11A/0.545
4hdqGNPRas-related protein Rap-1b/0.542
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.541
3tsoGNPRas-related protein Rab-25/0.538
2ce2GDPGTPase HRas/0.536
1xtsGTPGTP-binding protein Rheb/0.535
4xvrGNPGTPase HRas/0.535
4g0nGNPGTPase HRas/0.534
4cidANPEH domain-containing protein 2/0.533
1zd9GDPADP-ribosylation factor-like protein 8A/0.532
4dsnGCPGTPase KRas/0.531
2rgeGNPGTPase HRas/0.530
3v4fGNPGTPase HRas/0.530
3k8yGNPGTPase HRas/0.527
2mscGDPMHC class I alpha chain/0.523
1d5cGDPGTPase (Rab6)/0.520
3k9lGNPGTPase HRas/0.520
1tu3GNPRas-related protein Rab-5A/0.518
5difGNPGTP-binding nuclear protein Ran/0.518
1g16GDPRas-related protein SEC4/0.516
2cl6CAGGTPase HRas/0.516
4dlvGNPGTPase HRas/0.516
1z2aGDPRas-related protein Rab-23/0.515
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.513
5iqbGNPBifunctional AAC/APH2.3.10.513
3lbhGNPGTPase HRas/0.512
3lbnGNPGTPase HRas/0.511
3x1zGNPRas-related protein Rap-1b/0.511
3rs0GNPGTPase HRas/0.510
2c5lGTPGTPase HRas/0.509
3i3sGNPGTPase HRas/0.509
3rs4GNPGTPase HRas/0.508
3vhxGTPADP-ribosylation factor 6/0.508
3w3zGTPGTP-binding nuclear protein Ran/0.507
5b2zGNPGTPase HRas/0.507
3oivGNPGTPase HRas/0.506
3rslGNPGTPase HRas/0.506
5jljGNPGTP-binding nuclear protein Ran/0.505
1n83CLRNuclear receptor ROR-alpha/0.504
3l8yGNPGTPase HRas/0.504
3k7mFAD6-hydroxy-L-nicotine oxidase/0.502
4dltGNPGTPase HRas/0.502
2xtnGTPGTPase IMAP family member 2/0.501
3rs5GNPGTPase HRas/0.501
1kphSAHCyclopropane mycolic acid synthase 12.1.1.790.500
3rabGNPRas-related protein Rab-3A/0.500
4wa7GDPGTPase KRas/0.500
4rkfGNPRas-related protein Rab-3/0.499
3bbpGTPRas-related protein Rab-6A/0.498
3oesGNPGTPase RhebL1/0.497
2izfBTNStreptavidin/0.495
4dlzGNPGTPase HRas/0.494
1ky2GNPGTP-binding protein YPT7/0.493
3x1wGDPRas-related protein Rap-1b/0.493
4d0lGSPRas-related protein Rab-11A/0.493
1lfdGNPGTPase HRas/0.492
2rgcGNPGTPase HRas/0.492
4dlxGNPGTPase HRas/0.492
1g17GNPRas-related protein SEC4/0.491
1oixGDPRas-related protein Rab-11A/0.491
1z0dGDPRas-related protein Rab-5C/0.491
2rgbGNPGTPase HRas/0.491
3a6pGTPGTP-binding nuclear protein Ran/0.491
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.491
4js0GNPCell division control protein 42 homolog/0.491
2msdGNPMHC class I alpha chain/0.490
2ok8FADFerredoxin--NADP reductase, apicoplast/0.490
3d84NDPDihydrofolate reductase1.5.1.30.490
3lbiGNPGTPase HRas/0.489
3oiwGNPGTPase HRas/0.489
5iqgGDPBifunctional AAC/APH2.3.10.489
1d6w00RProthrombin3.4.21.50.488
1e96GTPRas-related C3 botulinum toxin substrate 1/0.488
3cobADPKinesin heavy chain-like protein/0.488
3rs7GNPGTPase HRas/0.488
4l9wGNPGTPase HRas/0.488
1n08ADPRiboflavin kinase2.7.1.260.487
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.486
5il1SAMN6-adenosine-methyltransferase 70 kDa subunit/0.485
4dlwGNPGTPase HRas/0.484
4l2xYL2Farnesyl pyrophosphate synthase2.5.1.100.484
5dhaGNPGTP-binding nuclear protein Ran/0.484
2j0vGDPRac-like GTP-binding protein ARAC7/0.483
3w8fNAD3-hydroxybutyrate dehydrogenase/0.483
4h5cYS4Farnesyl pyrophosphate synthase2.5.1.100.483
4pkwGM6Lethal factor3.4.24.830.483
1cxzGSPTransforming protein RhoA/0.482
4g01GDPRas-related protein RABF2b/0.482
4o25GTPGTP-binding protein Rheb/0.481
3ddw055Glycogen phosphorylase, liver form2.4.1.10.480
3nga3NGCasein kinase II subunit alpha2.7.11.10.480
4nyjGNPGTPase HRas/0.480
1zbdGTPRas-related protein Rab-3A/0.479
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.479
4demYS4Farnesyl pyrophosphate synthase2.5.1.100.479
4dlsGNPGTPase HRas/0.479
1dr2TAPDihydrofolate reductase1.5.1.30.478
1wdtGTPElongation factor G (EF-G-2)/0.478
2l0xGDPGTP-binding protein Rheb/0.478
3oiuGNPGTPase HRas/0.478
1dr3TAPDihydrofolate reductase1.5.1.30.477
1rx8NAPDihydrofolate reductase1.5.1.30.477
3ea5GDPGTP-binding nuclear protein Ran/0.477
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.476
5iqdGNPBifunctional AAC/APH2.3.10.476
1db48INPhospholipase A2, membrane associated/0.475
1ypkCCRProthrombin3.4.21.50.475
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.475
3wyfGTPGTP-binding nuclear protein/0.475
1dr3HBIDihydrofolate reductase1.5.1.30.474
1pw1HELD-alanyl-D-alanine carboxypeptidase3.4.16.40.474
3k7tFAD6-hydroxy-L-nicotine oxidase/0.474
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.473
1opbRETRetinol-binding protein 2/0.473
1p4mADPRiboflavin kinase2.7.1.260.473
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.473
1giaGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.472
1vyrFMNPentaerythritol tetranitrate reductase/0.472
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.472
3pcrGTPADP-ribosylation factor 6/0.472
1dr5NAPDihydrofolate reductase1.5.1.30.471
2ffqGSPRas-related protein Rab-6B/0.471
2vprTDCTetracycline repressor protein class H/0.471
3c15GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.471
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.471
1zc4GNPRas-related protein Ral-A/0.470
2hamC33Vitamin D3 receptor/0.470
3i587NA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.470
4a7b3W5Collagenase 33.4.240.470
4h5eYS4Farnesyl pyrophosphate synthase2.5.1.100.470
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.470
5iqiGNPBifunctional AAC/APH2.3.10.470
2yg4FADPutrescine oxidase/0.469
4mitGTPRho-related protein racC/0.469
1k5dGNPGTP-binding nuclear protein Ran/0.468
1pq944BOxysterols receptor LXR-beta/0.468
3bi6396Wee1-like protein kinase2.7.10.20.468
3vv8B02Beta-secretase 13.4.23.460.468
1rszDIHPurine nucleoside phosphorylase2.4.2.10.467
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.467
3zeiAWHO-acetylserine sulfhydrylase/0.467
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.466
2r5nTPPTransketolase 1/0.466
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.466
3kudGDPGTPase HRas/0.466
4qi5FADCellobiose dehydrogenase/0.466
4r1lADPPhenylacetate-coenzyme A ligase/0.466
1z2nADPInositol-tetrakisphosphate 1-kinase2.7.1.1340.465
2dxdANPNucleoside diphosphate kinase2.7.4.60.465
2w06FRVCyclin-dependent kinase 22.7.11.220.465
4an4DUDPutative glycosyl transferase/0.465
4dsuGDPGTPase KRas/0.465
1gpeFADGlucose oxidase1.1.3.40.464
1hdoNAPFlavin reductase (NADPH)/0.464
1s3uTQDDihydrofolate reductase1.5.1.30.464
2x9dITCTetracycline repressor protein class D/0.464
3rhaFDAPutrescine oxidase/0.464
4hdoGNPRas-related protein Rap-1b/0.464
4orkGDPBifunctional AAC/APH2.3.10.464
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.464
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.463
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.463
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.463
3th5GNPRas-related C3 botulinum toxin substrate 1/0.463
1dgmADNAdenosine kinase2.7.1.200.462
1njjORXOrnithine decarboxylase/0.462
1rx8FOLDihydrofolate reductase1.5.1.30.462
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.462
4g1y0VOVitamin D3 receptor A/0.462
4o2lGTPGTP-binding protein Rheb/0.462
5eccNAPDehydrofolate reductase type I/0.462
1l2oADPMyosin heavy chain, striated muscle/0.461
1sreHABStreptavidin/0.461
2xw19NVSerum albumin/0.461
3vt9YI4Vitamin D3 receptor/0.461
4cmfPXGUncharacterized protein/0.461
1drhNAPDihydrofolate reductase1.5.1.30.460
1jmiUMPThymidylate synthase/0.460
1vzaUMPThymidylate synthase/0.460
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.460
2bkuGTPGTP-binding nuclear protein Ran/0.460
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.460
2r8oT5XTransketolase 1/0.460
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.460
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
4a99FADTetX family tetracycline inactivation enzyme/0.460
1dhiMTXDihydrofolate reductase1.5.1.30.459
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.459
2r8pT6FTransketolase 1/0.459
3rimTPPTransketolase2.2.1.10.459
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.459
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.459
4ceqQCHIntegrase/0.459
4dpeNGHStromelysin-13.4.24.170.459
4ehv0SJMitogen-activated protein kinase 14/0.459
4fidGDPG protein alpha subunit, putative/0.459
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4lzwTHMUridine phosphorylase/0.459
1ia3TQ5Dihydrofolate reductase1.5.1.30.458
1ibrGNPGTP-binding nuclear protein Ran/0.458
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.458
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.458
2fhnBNIAvidin-related protein 4/5/0.458
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.458
2izkGLLStreptavidin/0.458
2ji6TPWOxalyl-CoA decarboxylase4.1.1.80.458
2o7oDXTTetracycline repressor protein class D/0.458
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.458
2wlgSOPPolysialic acid O-acetyltransferase/0.458
2xlrFADPutative flavin-containing monooxygenase/0.458
3gonANPPhosphomevalonate kinase/0.458
3pd4A3GThreonine--tRNA ligase6.1.1.30.458
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.458
4cf23GMIntegrase/0.458
4d7mTDCTetracycline repressor protein class D/0.458
4xg1LLPDiaminopimelate decarboxylase/0.458
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.457
1rx1NAPDihydrofolate reductase1.5.1.30.457
1s0xC3SNuclear receptor ROR-alpha/0.457
1svwGTPProbable GTP-binding protein EngB/0.457
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.457
2fj1CTCTetracycline repressor protein class D/0.457
2g8dUMPThymidylate synthase/0.457
2gcpGSPRho-related GTP-binding protein RhoC/0.457
3dds26BGlycogen phosphorylase, liver form2.4.1.10.457
3kwn23ZCathepsin S3.4.22.270.457
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.457
4pnmNU1Tankyrase-22.4.2.300.457
1fdrFADFerredoxin--NADP reductase1.18.1.20.456
1rxhBNIStreptavidin/0.456
1wy7SAHUncharacterized protein/0.456
1x1cSAHC-20 methyltransferase/0.456
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.456
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.456
3fpkFADFerredoxin-NADP reductase/0.456
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.456
4dsoGSPGTPase KRas/0.456
4gg50J3Hepatocyte growth factor receptor2.7.10.10.456
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.456
5iqaGNPBifunctional AAC/APH2.3.10.456
1mmaADPMyosin-2 heavy chain/0.455
1zk7FADMercuric reductase1.16.1.10.455
2bbwGP5Adenylate kinase 4, mitochondrial/0.455
2d4h5GPGuanylate-binding protein 1/0.455
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.455
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.455
3w1xXRODihydroorotate dehydrogenase (fumarate)1.3.98.10.455
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.455
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
1luqBTNStreptavidin/0.454
1lwxAZDNucleoside diphosphate kinase, cytosolic2.7.4.60.454
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.454
1rjgSAHLeucine carboxyl methyltransferase 12.1.1.2330.454
1z6lFADPolyamine oxidase FMS1/0.454
2bxmIMNSerum albumin/0.454
2geuCOKPantothenate kinase2.7.1.330.454
2qbs024Tyrosine-protein phosphatase non-receptor type 13.1.3.480.454
3eg5GNPCell division control protein 42 homolog/0.454
3jziJZLBiotin carboxylase6.3.4.140.454
3w8eNAD3-hydroxybutyrate dehydrogenase/0.454
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.454
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.453
1ngsTPPTransketolase 12.2.1.10.453
1wn3HXCPhenylacetic acid degradation protein PaaI/0.453
1z7yAA5Cysteine synthase 12.5.1.470.453
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.453
2hu2NADC-terminal binding protein 1/0.453
2r2mI50Prothrombin3.4.21.50.453
2rgoFADAlpha-Glycerophosphate Oxidase/0.453
2w71L23Biotin carboxylase6.3.4.140.453
3gtsD3MDdmC/0.453
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.453
4ii4BYC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.453
4ju21O0Genome polyprotein2.7.7.480.453
1am4GNPCell division control protein 42 homolog/0.452
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.452
3kz1GSPTransforming protein RhoA/0.452
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.452
3t7vSAM3-methylornithine synthase/0.452
3v4aPK1Androgen receptor/0.452
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.452
4iteTEYVitamin D3 receptor/0.452
5agyGTBTau class glutathione S-transferase/0.452
1mvtDTMDihydrofolate reductase1.5.1.30.451
1sriDMBStreptavidin/0.451
1t57FMNConserved protein/0.451
4kgkGTPUncharacterized protein/0.451
4xr9TMPCalS8/0.451
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.451
5ez4NADBetaine-aldehyde dehydrogenase/0.451
1cs4GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.450
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.450
1m78NDPDihydrofolate reductase1.5.1.30.450
1n5dNDPCarbonyl reductase [NADPH] 1/0.450
1vzbUMPThymidylate synthase/0.450
1wc3APCAdenylate cyclase/0.450
2a3iC0RMineralocorticoid receptor/0.450
2fznFADBifunctional protein PutA1.5.5.20.450
3p67FMNPentaerythritol tetranitrate reductase/0.450
3p8jFMNPentaerythritol tetranitrate reductase/0.450
4a8v2ANMajor pollen allergen Bet v 1-J/0.450
4eh8IRGMitogen-activated protein kinase 14/0.450
4jicFMNGTN Reductase/0.450
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.450
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1vg8GNPRas-related protein Rab-7a/0.449
2jdcCAOProbable acetyltransferase/0.449
2yg6FADPutrescine oxidase/0.449
3b9lAZZSerum albumin/0.449
3bgxMEFThymidylate synthase/0.449
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
3vt3VDXVitamin D3 receptor/0.449
4buwF33Tankyrase-22.4.2.300.449
4eh7IRGMitogen-activated protein kinase 14/0.449
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.449
5bylGCPBifunctional AAC/APH2.3.10.449
1dfoPLGSerine hydroxymethyltransferase2.1.2.10.448
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.448
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.448
1srfMTBStreptavidin/0.448
1t4v14AProthrombin3.4.21.50.448
1txtCAAHMG-CoA synthase/0.448
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.448
2p9hIPTLactose operon repressor/0.448
2ywlFADThioredoxin reductase related protein/0.448
3oibFDAPutative acyl-CoA dehydrogenase/0.448
3r7wGNPGTP-binding protein GTR2/0.448
3refGDPRho family GTPase/0.448
4iarERM5-hydroxytryptamine receptor 1B/0.448
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.448
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.447
1gky5GPGuanylate kinase2.7.4.80.447
1jjeBYSBeta-lactamase/0.447
1njaDCMThymidylate synthase/0.447
1x7gNAPPutative ketoacyl reductase1.3.10.447
1z6tADPApoptotic protease-activating factor 1/0.447
2bswCAOProbable acetyltransferase/0.447
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.447
2g8aUMPThymidylate synthase/0.447
2zuiCAMCamphor 5-monooxygenase1.14.15.10.447
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
3k5gBJCBeta-secretase 13.4.23.460.447
3mp3HGGHydroxymethylglutaryl-CoA lyase, mitochondrial4.1.3.40.447
3x2fNAIAdenosylhomocysteinase/0.447
4k5p1OSM1 family aminopeptidase3.4.110.447
4nm9FADBifunctional protein PutA/0.447
1rkhVD2Vitamin D3 receptor/0.446
2g86UMPThymidylate synthase/0.446
2re8GSUGlutamine--tRNA ligase6.1.1.180.446
3e5hGNPRas-related protein Rab-28/0.446
3i7g732Collagenase 33.4.240.446
3s3vTOPDihydrofolate reductase1.5.1.30.446
4gevCB3Thymidylate synthase/0.446
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.446
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4x5iFOLDihydrofolate reductase1.5.1.30.446
4xqcNADHomospermidine synthase2.5.1.440.446
5di3GNPADP-ribosylation factor-like protein 3/0.446
1jscTPPAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.445
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.445
1tehNADAlcohol dehydrogenase class-31.1.1.10.445
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.445
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.445
2b8v3BNBeta-secretase 13.4.23.460.445
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
2d1nFA4Collagenase 33.4.240.445
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.445
2g89UMPThymidylate synthase/0.445
2ic5GDPRas-related C3 botulinum toxin substrate 3/0.445
2j9gANPBiotin carboxylase6.3.4.140.445
2yg5FADPutrescine oxidase/0.445
3gb4D3MDdmC/0.445
3ha3SAHHydroxymycolate synthase MmaA42.1.10.445
3ldoANP78 kDa glucose-regulated protein/0.445
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
3pt9SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.445
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.445
4imgNGFN-acetylneuraminate lyase/0.445
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.445
1e4gATPCell division protein FtsA/0.444
1jmfUMPThymidylate synthase/0.444
1tj0FADBifunctional protein PutA1.5.5.20.444
2ozrGG1Collagenase 33.4.240.444
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.444
3qge26FGenome polyprotein2.7.7.480.444
3up3XCAaceDAF-12/0.444
4buxF35Tankyrase-22.4.2.300.444
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.444
4djx0KQBeta-secretase 13.4.23.460.444
4kne1CYDihydrofolate reductase1.5.1.30.444
4m6jNDPDihydrofolate reductase1.5.1.30.444
5k7wSAHN6-adenosine-methyltransferase 70 kDa subunit/0.444
5kf2ACOPredicted acetyltransferase/0.444
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.443
1n4hREANuclear receptor ROR-beta/0.443
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.443
1udaUFGUDP-glucose 4-epimerase5.1.3.20.443
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
2c2aADPSensor histidine kinase/0.443
2f3rG5PGuanylate kinase2.7.4.80.443
2fonFADAcyl-coenzyme A oxidase/0.443
2tprFADTrypanothione reductase1.8.1.120.443
2vczVC3Hematopoietic prostaglandin D synthase/0.443
3ijdC2FMethylenetetrahydrofolate reductase/0.443
3m53SAHHistone-lysine N-methyltransferase SETD72.1.1.430.443
3p74FMNPentaerythritol tetranitrate reductase/0.443
3phiNDPShikimate dehydrogenase (NADP(+))/0.443
3qs817DAnthranilate phosphoribosyltransferase/0.443
3v1nHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.443
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.443
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.443
4gojGNPADP-ribosylation factor-like protein 3/0.443
4u0mGTPCyclic GMP-AMP synthase/0.443
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.443
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.443
1a2bGSPTransforming protein RhoA/0.442
1kp2ATPArgininosuccinate synthase6.3.4.50.442
1n9mBTNStreptavidin/0.442
1umaIN2Prothrombin3.4.21.50.442
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.442
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.442
2gvdFKPAdenylate cyclase type 2/0.442
2gvdFKPAdenylate cyclase type 5/0.442
2j62GSZO-GlcNAcase NagJ/0.442
2xlsFADPutative flavin-containing monooxygenase/0.442
3a783EVVitamin D3 receptor/0.442
3aw9GDUNAD-dependent epimerase/dehydratase/0.442
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.442
3ngq1PSCCR4-NOT transcription complex subunit 6-like3.1.13.40.442
3vrwYS5Vitamin D3 receptor/0.442
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.442
3zoiM2WIsopenicillin N synthase1.21.3.10.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4bfsZVSPantothenate kinase2.7.1.330.442
4ceoG0TIntegrase/0.442
4g67SAHUncharacterized ACR, COG1565 superfamily/0.442
4jauADPSensor histidine kinase/0.442
4qzuRTLRetinol-binding protein 2/0.442
4relKMPGlycosyltransferase/0.442
4tm0NAPKtzI/0.442
4xz3COAAcyl-CoA synthetase (NDP forming)/0.442
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
5jjrSAHGenome polyprotein/0.442
1dhrNADDihydropteridine reductase1.5.1.340.441
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
1j4jACOAcetyltransferase2.3.10.441
1nhkCMPNucleoside diphosphate kinase2.7.4.60.441
1pd9CO4Dihydrofolate reductase1.5.1.30.441
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.441
1uvsI11Prothrombin3.4.21.50.441
1wklATPNucleoside diphosphate kinase/0.441
1wmaAB3Carbonyl reductase [NADPH] 11.1.1.1840.441
2a84ATPPantothenate synthetase6.3.2.10.441
2c29NAPDihydroflavonol 4-reductase/0.441
2ftoTMPThymidylate synthase/0.441
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.441
2xpuTDCTetracycline repressor protein class D/0.441
2yy7NADL-threonine dehydrogenase/0.441
3aosJH2Hemolymph juvenile hormone binding protein/0.441
3cqeP91Wee1-like protein kinase2.7.10.20.441
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3golXNDGenome polyprotein2.7.7.480.441
3gwdNAPCyclohexanone monooxygenase/0.441
4bueJQFTankyrase-22.4.2.300.441
4e2dFMNDehydrogenase/0.441
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
4f700STCyclin-dependent kinase 82.7.11.220.441
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.441
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4p9dTMPDeoxycytidylate deaminase/0.441
4rx6ATPNitrogen regulatory PII-like protein/0.441
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.441
1cf3FADGlucose oxidase1.1.3.40.440
1disBDMDihydrofolate reductase1.5.1.30.440
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.440
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.440
1s6qTPBGag-Pol polyprotein2.7.7.490.440
1youPFDCollagenase 33.4.240.440
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.440
2y3fBTNStreptavidin/0.440
3f03FMNPentaerythritol tetranitrate reductase/0.440
3mykANPMyosin-2 heavy chain/0.440
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.440
3u9eCOALmo1369 protein/0.440
4avlTMPPolymerase acidic protein/0.440
4rnwFMNNADPH dehydrogenase 11.6.99.10.440
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.440
5dhgDGVNociceptin receptor/0.440