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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1pyxANPGlycogen synthase kinase-3 beta2.7.11.26

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1pyxANPGlycogen synthase kinase-3 beta2.7.11.261.000
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.608
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.602
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.599
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.593
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.592
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.589
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.585
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.573
5drdATPAurora kinase A2.7.11.10.567
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.565
1ol5ADPAurora kinase A2.7.11.10.557
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.551
3du8553Glycogen synthase kinase-3 beta2.7.11.260.549
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.549
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.548
2dwbANPAurora kinase A2.7.11.10.547
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.546
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.546
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.545
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.543
5dt4ATPAurora kinase A2.7.11.10.541
1mq4ADPAurora kinase A2.7.11.10.537
3c50ADPRhodopsin kinase/0.535
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.535
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.534
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.532
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.530
2acxANPG protein-coupled receptor kinase 62.7.11.160.527
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.527
5dt3ATPAurora kinase A2.7.11.10.527
4jbpYPHAurora kinase A2.7.11.10.525
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.522
2qo9ANPEphrin type-A receptor 32.7.10.10.520
3qc9ADPRhodopsin kinase/0.520
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.518
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.518
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.517
4deeADPAurora kinase A2.7.11.10.517
3k5uPFQAurora kinase A2.7.11.10.516
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.516
5dn3ATPAurora kinase A2.7.11.10.516
4utdACPAurora kinase A2.7.11.10.515
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.511
4jajXU1Aurora kinase A2.7.11.10.510
3efwAK8Aurora kinase A2.7.11.10.509
1lp4ANPCasein kinase II subunit alpha2.7.11.10.507
2np8CC3Aurora kinase A2.7.11.10.507
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.506
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.505
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.504
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.504
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.503
2hog710Serine/threonine-protein kinase Chk12.7.11.10.502
4oavACP2-5A-dependent ribonuclease3.1.260.500
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.496
4oauADP2-5A-dependent ribonuclease3.1.260.496
5dosATPAurora kinase A2.7.11.10.496
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.495
1ol7ADPAurora kinase A2.7.11.10.494
4hvh19RTyrosine-protein kinase JAK32.7.10.20.494
5dnrATPAurora kinase A2.7.11.10.493
3a7jADPSerine/threonine-protein kinase 242.7.11.10.492
3c4wATPRhodopsin kinase/0.492
3c4zADPRhodopsin kinase/0.492
1jstATPCyclin-dependent kinase 22.7.11.220.491
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.491
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.491
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.490
1u54ACPActivated CDC42 kinase 1/0.490
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.490
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.490
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.489
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.489
4jbqVX6Aurora kinase A2.7.11.10.489
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.489
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.488
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.488
4qnaX11Serine/threonine-protein kinase 242.7.11.10.488
3zh8C58Protein kinase C iota type2.7.11.130.487
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.487
4ix5ANPUncharacterized protein/0.487
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.487
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.486
2j4z626Aurora kinase A2.7.11.10.486
4jqeANPCasein kinase II subunit alpha2.7.11.10.486
4o0sADNAurora kinase A2.7.11.10.486
3t8oATPRhodopsin kinase/0.485
3le62BZCyclin-dependent kinase 22.7.11.220.484
4c3pACPAurora kinase A2.7.11.10.484
4jboWPHAurora kinase A2.7.11.10.484
4nm5ADPGlycogen synthase kinase-3 beta2.7.11.260.484
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.483
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.483
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.483
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.482
4eomATPCyclin-dependent kinase 22.7.11.220.482
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.481
3i60E86Mitogen-activated protein kinase 12.7.11.240.481
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.481
5dr2ATPAurora kinase A2.7.11.10.481
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.480
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.480
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.479
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.479
1unlRRCCyclin-dependent-like kinase 52.7.11.10.478
3gxlQIGTGF-beta receptor type-12.7.11.300.478
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.478
4dgmAGICasein kinase II subunit alpha2.7.11.10.478
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.478
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.477
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.477
4jr7GNPCasein kinase II subunit alpha2.7.11.10.477
4lopSB4Mitogen-activated protein kinase 14/0.477
4qmzB49Serine/threonine-protein kinase 242.7.11.10.477
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.477
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.476
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.476
4riyADPEpidermal growth factor receptor2.7.10.10.476
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.475
2henADPEphrin type-B receptor 22.7.10.10.475
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.475
4fkv61KCyclin-dependent kinase 22.7.11.220.475
5dpvSKEAurora kinase A2.7.11.10.475
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.474
2uzlC94Cyclin-dependent kinase 22.7.11.220.474
3c4xATPRhodopsin kinase/0.474
3tnwF18Cyclin-dependent kinase 22.7.11.220.474
4gk2L66Ephrin type-A receptor 32.7.10.10.474
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.474
4qmpDKISerine/threonine-protein kinase 242.7.11.10.474
5aacVGHALK tyrosine kinase receptor2.7.10.10.474
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.473
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.473
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.473
4g2fC07Ephrin type-A receptor 32.7.10.10.473
4gk3L87Ephrin type-A receptor 32.7.10.10.473
4zseANPEpidermal growth factor receptor2.7.10.10.473
5dr9SKEAurora kinase A2.7.11.10.473
1csnATPCasein kinase I homolog 12.7.11.10.472
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.472
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.472
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.471
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.471
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.471
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.471
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.471
2w1fL0FAurora kinase A2.7.11.10.471
3be9P04Casein kinase II subunit alpha2.7.11.10.471
4jia1K3Tyrosine-protein kinase JAK2/0.471
6cp4CAMCamphor 5-monooxygenase1.14.15.10.471
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.470
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.470
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4bn1ADPAurora kinase A2.7.11.10.470
4e4m0NHTyrosine-protein kinase JAK2/0.470
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.470
1di8DTQCyclin-dependent kinase 22.7.11.220.469
2xru400Aurora kinase A2.7.11.10.469
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.469
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.469
4fv7E94Mitogen-activated protein kinase 12.7.11.240.469
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.469
4qmlANPSerine/threonine-protein kinase 242.7.11.10.469
1jpaANPEphrin type-B receptor 22.7.10.10.468
1oi9N20Cyclin-dependent kinase 22.7.11.220.468
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.468
4c3rACPAurora kinase A2.7.11.10.468
1dayGNPCasein kinase II subunit alpha2.7.11.10.467
1fvv107Cyclin-dependent kinase 22.7.11.220.467
2iw84SPCyclin-dependent kinase 22.7.11.220.467
2py3ACPFibroblast growth factor receptor 2/0.467
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.467
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.467
4hvg19QTyrosine-protein kinase JAK32.7.10.20.467
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4z34ON7Lysophosphatidic acid receptor 1/0.467
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.466
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.466
5e8wSTUTGF-beta receptor type-12.7.11.300.466
1bw9NADPhenylalanine dehydrogenase/0.465
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
1jnkANPMitogen-activated protein kinase 102.7.11.240.465
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.465
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.465
3hx4ANPCalmodulin-domain protein kinase 1/0.465
4aotGW8Serine/threonine-protein kinase 102.7.11.10.465
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.465
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.465
4wboANWRhodopsin kinase/0.465
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
2qocANPEphrin type-A receptor 32.7.10.10.464
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4c62XWWTyrosine-protein kinase JAK2/0.464
5e8xSTUTGF-beta receptor type-12.7.11.300.464
2qo7ANPEphrin type-A receptor 32.7.10.10.463
2y3rTRKTamL/0.463
2zdt46CMitogen-activated protein kinase 102.7.11.240.463
3nszANPCasein kinase II subunit alpha2.7.11.10.463
3s2pPMUCyclin-dependent kinase 22.7.11.220.463
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.463
4dgo0JWCasein kinase II subunit alpha2.7.11.10.463
4ix4ADPUncharacterized protein/0.463
1ol6ATPAurora kinase A2.7.11.10.462
1x2hLPALipoate-protein ligase A6.3.1.200.462
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.462
3hmm855TGF-beta receptor type-12.7.11.300.462
4kigENOPhenylpyruvate C(3)-methyltransferase2.1.1.2810.462
1ke6LS2Cyclin-dependent kinase 22.7.11.220.461
1vjy460TGF-beta receptor type-12.7.11.300.461
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.461
2c6tDT5Cyclin-dependent kinase 22.7.11.220.461
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.461
3a60STURibosomal protein S6 kinase beta-12.7.11.10.461
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4i22IREEpidermal growth factor receptor2.7.10.10.461
4lfiGNPCasein kinase II subunit alpha2.7.11.10.461
4y95746Tyrosine-protein kinase/0.461
1phgMYTCamphor 5-monooxygenase1.14.15.10.460
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.460
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.460
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.460
3wv9FEGHmd co-occurring protein HcgE/0.460
4a8v2ANMajor pollen allergen Bet v 1-J/0.460
4fkg4CKCyclin-dependent kinase 22.7.11.220.460
4kb81QOCasein kinase I isoform delta2.7.11.10.460
4n57ADPAPH(2'')-Id/0.460
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.459
3e5aVX6Aurora kinase A2.7.11.10.459
3eb0DRKUncharacterized protein/0.459
3w16P9JAurora kinase A2.7.11.10.459
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.459
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.458
2pvnP63Casein kinase II subunit alpha2.7.11.10.458
2x1nX1NCyclin-dependent kinase 22.7.11.220.458
3oom507Activin receptor type-12.7.11.300.458
4eor4SPCyclin-dependent kinase 22.7.11.220.458
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.458
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.457
3uo50BXAurora kinase A2.7.11.10.457
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.457
4g170VNCasein kinase I isoform gamma-32.7.11.10.457
4l4cCAMCamphor 5-monooxygenase1.14.15.10.457
1xddAAYIntegrin alpha-L/0.456
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.456
2pzpACPFibroblast growth factor receptor 2/0.456
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.456
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.456
1gebCAMCamphor 5-monooxygenase1.14.15.10.455
1rw8580TGF-beta receptor type-12.7.11.300.455
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.455
3a62STURibosomal protein S6 kinase beta-12.7.11.10.455
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.455
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.455
3w18N13Aurora kinase A2.7.11.10.455
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.455
4ix6ADPUncharacterized protein/0.455
4k33ACPFibroblast growth factor receptor 32.7.10.10.455
4mwhATPCasein kinase II subunit alpha2.7.11.10.455
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.454
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.454
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.454
3fwjCAMCamphor 5-monooxygenase1.14.15.10.454
3mdvCL6Cholesterol 24-hydroxylase/0.454
3r9hZ67Cyclin-dependent kinase 22.7.11.220.454
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.454
1gij2PUCyclin-dependent kinase 22.7.11.220.453
1t86CAMCamphor 5-monooxygenase1.14.15.10.453
1vyw292Cyclin-dependent kinase 22.7.11.220.453
2bhhRYUCyclin-dependent kinase 22.7.11.220.453
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.453
2x6dX6DAurora kinase A2.7.11.10.453
2xngA0HAurora kinase A2.7.11.10.453
4j97ACPFibroblast growth factor receptor 2/0.453
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.453
4loqSB4Mitogen-activated protein kinase 14/0.453
4qysPLRTryptophan synthase beta chain 24.2.1.200.453
5e92ANPTGF-beta receptor type-22.7.11.300.453
1e9hINRCyclin-dependent kinase 22.7.11.220.452
1phePIYCamphor 5-monooxygenase1.14.15.10.452
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1t85CAMCamphor 5-monooxygenase1.14.15.10.452
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.452
2cchATPCyclin-dependent kinase 22.7.11.220.452
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.452
2zaxCAMCamphor 5-monooxygenase1.14.15.10.452
3ijdC2FMethylenetetrahydrofolate reductase/0.452
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.452
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.452
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.452
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4xlvACPInsulin receptor2.7.10.10.452
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.452
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.451
2w1eL0EAurora kinase A2.7.11.10.451
2w1gL0GAurora kinase A2.7.11.10.451
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.451
3ddpRC8Cyclin-dependent kinase 22.7.11.220.451
3my5RFZCyclin-dependent kinase 22.7.11.220.451
3so9017Pol protein/0.451
3t3q9PLCytochrome P450 2A61.14.130.451
3wowANPCasein kinase II subunit alpha2.7.11.10.451
4bgg844Activin receptor type-12.7.11.300.451
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.451
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.451
4gmy0X5Tyrosine-protein kinase JAK2/0.451
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.451
4nj32KDCyclin-dependent kinase 22.7.11.220.451
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.450
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.450
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.450
2excJNKMitogen-activated protein kinase 102.7.11.240.450
2qoqANPEphrin type-A receptor 32.7.10.10.450
2r64740Cyclin-dependent kinase 22.7.11.220.450
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.450
3ddqRRCCyclin-dependent kinase 22.7.11.220.450
3oroAGSSerine/threonine protein kinase/0.450
3qwkX62Cyclin-dependent kinase 22.7.11.220.450
3wecAUICytochrome P450/0.450
3wrhCAMCamphor 5-monooxygenase1.14.15.10.450
4erwSTUCyclin-dependent kinase 22.7.11.220.450
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.450
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.449
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.449
2pvhP19Casein kinase II subunit alpha2.7.11.10.449
2qboCAMCamphor 5-monooxygenase1.14.15.10.449
2vd5BI8Myotonin-protein kinase2.7.11.10.449
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.449
2y3sTIRTamL/0.449
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.449
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3friSAH16S rRNA methylase/0.449
3js2VM1Fibroblast growth factor receptor 1/0.449
3rni21ZCyclin-dependent kinase 22.7.11.220.449
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.449
4eok4SPCyclin-dependent kinase 22.7.11.220.449
4fob0USALK tyrosine kinase receptor2.7.10.10.449
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.449
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.449
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.449
5cvcPLPSerine racemase/0.449
1oiyN41Cyclin-dependent kinase 22.7.11.220.448
1pkdUCNCyclin-dependent kinase 22.7.11.220.448
1pxlCK4Cyclin-dependent kinase 22.7.11.220.448
1zeoC01Peroxisome proliferator-activated receptor gamma/0.448
2c5yMTWCyclin-dependent kinase 22.7.11.220.448
2csnCKICasein kinase I homolog 12.7.11.10.448
2qbmCAMCamphor 5-monooxygenase1.14.15.10.448
2w1dL0DAurora kinase A2.7.11.10.448
2xikJ60Serine/threonine-protein kinase 252.7.11.10.448
2z97CAMCamphor 5-monooxygenase1.14.15.10.448
3eljGS7Mitogen-activated protein kinase 82.7.11.240.448
3tqhNDPQuinone oxidoreductase/0.448
3ttjJBIMitogen-activated protein kinase 102.7.11.240.448
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.448
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.448
4g6oE28Mitogen-activated protein kinase 12.7.11.240.448
5auwQUEDeath-associated protein kinase 12.7.11.10.448
1ir3ANPInsulin receptor2.7.10.10.447
1ke9LS5Cyclin-dependent kinase 22.7.11.220.447
1vyzN5BCyclin-dependent kinase 22.7.11.220.447
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.447
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.447
2wihP48Cyclin-dependent kinase 22.7.11.220.447
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.447
2znq401Peroxisome proliferator-activated receptor delta/0.447
3clyACPFibroblast growth factor receptor 2/0.447
4bcnT9NCyclin-dependent kinase 22.7.11.220.447
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.447
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.446
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.446
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.446
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.446
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.446
2xuuADPDeath-associated protein kinase 12.7.11.10.446
2z3uCRRCytochrome P450/0.446
3cppCAMCamphor 5-monooxygenase1.14.15.10.446
3icsCOACoenzyme A disulfide reductase/0.446
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3s79ASDAromatase1.14.14.140.446
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.446
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.446
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.446
1dz6CAMCamphor 5-monooxygenase1.14.15.10.445
1pmn984Mitogen-activated protein kinase 102.7.11.240.445
1v0pPVBCell division control protein 2 homolog2.7.11.220.445
1y0s331Peroxisome proliferator-activated receptor delta/0.445
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2b52D42Cyclin-dependent kinase 22.7.11.220.445
2c6dANPAurora kinase A2.7.11.10.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2f2cAP9Cyclin-dependent kinase 62.7.11.220.445
3fwfCAMCamphor 5-monooxygenase1.14.15.10.445
3l0lHC3Nuclear receptor ROR-gamma/0.445
3r9uFADThioredoxin reductase/0.445
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.445
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.445
4qmySTUSerine/threonine-protein kinase 242.7.11.10.445
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1yw2PGJMitogen-activated protein kinase 14/0.444
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.444
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.444
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.444
2gjlFMNNitronate monooxygenase1.13.12.160.444
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.444
2vttLZDCyclin-dependent kinase 22.7.11.220.444
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.444
3ggfGVDSerine/threonine-protein kinase 26/0.444
3tjsD0RCytochrome P450 3A4/0.444
3ttiKBIMitogen-activated protein kinase 102.7.11.240.444
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4cp4CAMCamphor 5-monooxygenase1.14.15.10.444
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.444
4ek610KCyclin-dependent kinase 22.7.11.220.444
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.444
5l8kADPAurora kinase A2.7.11.10.444
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1h1r6CPCyclin-dependent kinase 22.7.11.220.443
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.443
3cgfJNFMitogen-activated protein kinase 102.7.11.240.443
3dt1P40Mitogen-activated protein kinase 14/0.443
3l63CAMCamphor 5-monooxygenase1.14.15.10.443
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3pm0BHFCytochrome P450 1B1/0.443
3zep1NXTyrosine-protein kinase JAK32.7.10.20.443
3zewSTUEphrin type-B receptor 42.7.10.10.443
4bcpT3CCyclin-dependent kinase 22.7.11.220.443
4c61LMMTyrosine-protein kinase JAK2/0.443
4c9pCAMCytochrome P450/0.443
4dymIYZActivin receptor type-12.7.11.300.443
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.443
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.443
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4qms1N1Serine/threonine-protein kinase 242.7.11.10.443
5dr6SKEAurora kinase A2.7.11.10.443
1drhNAPDihydrofolate reductase1.5.1.30.442
1dz8CAMCamphor 5-monooxygenase1.14.15.10.442
1e3eNAIAlcohol dehydrogenase 41.1.1.10.442
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.442
1w2xRCPAcetyl-CoA carboxylase/0.442
2bkzSBCCyclin-dependent kinase 22.7.11.220.442
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.442
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.442
2izrBRKCasein kinase I isoform gamma-32.7.11.10.442
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.442
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2vgoAD5Aurora kinase B-A2.7.11.10.442
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.442
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.442
3zmmF9JTyrosine-protein kinase JAK2/0.442
4c9oCAMCytochrome P450/0.442
4ejgNCTCytochrome P450 2A131.14.14.10.442
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.442
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.442
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.442
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.442
5a9sNAPPutative dehydrogenase/0.442
5cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1dyiFOLDihydrofolate reductase1.5.1.30.441
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1m2qMNXCasein kinase II subunit alpha2.7.11.10.441
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.441
1uyuCAMCamphor 5-monooxygenase1.14.15.10.441
2a7r5GPGMP reductase 2/0.441
2btrU73Cyclin-dependent kinase 22.7.11.220.441
2eufLQQCyclin-dependent kinase 62.7.11.220.441
2q9fC3SCholesterol 24-hydroxylase/0.441
2v7a627Tyrosine-protein kinase ABL12.7.10.20.441
2wxvWXVCyclin-dependent kinase 22.7.11.220.441
2yxuATPPyridoxal kinase2.7.1.350.441
3hl7I47Mitogen-activated protein kinase 14/0.441
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3t113T1Gag-Pol polyprotein3.4.23.160.441
4fi1ATPCasein kinase II subunit alpha2.7.11.10.441
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.441
4g3rCAMCamphor 5-monooxygenase1.14.15.10.441
4lrjANPUncharacterized protein/0.441
4qi5FADCellobiose dehydrogenase/0.441
4tuvCPZCytochrome P450 1191.140.441
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.441
1orrNADCDP-paratose 2-epimerase/0.440
1udaUFGUDP-glucose 4-epimerase5.1.3.20.440
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.440
2fy4COACholine O-acetyltransferase2.3.1.60.440
2j0m4STFocal adhesion kinase 12.7.10.20.440
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.440
3ezrEZRCyclin-dependent kinase 22.7.11.220.440
3fwgCAMCamphor 5-monooxygenase1.14.15.10.440
3icrCOACoenzyme A disulfide reductase/0.440
3igoANPCalmodulin-domain protein kinase 1, putative/0.440
3kvxFMYMitogen-activated protein kinase 102.7.11.240.440
3r7eX88Cyclin-dependent kinase 22.7.11.220.440
3r9oZ71Cyclin-dependent kinase 22.7.11.220.440
3roy22ZCyclin-dependent kinase 22.7.11.220.440
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.440
3vspEK8Peroxisome proliferator-activated receptor gamma/0.440
3vthAP2Carbamoyltransferase/0.440
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.440
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.440
4fk8FADFerredoxin--NADP reductase/0.440
4fkt48KCyclin-dependent kinase 22.7.11.220.440
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.440
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.440