sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 1.000 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.498 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.491 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.488 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.487 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.487 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.486 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.485 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.482 | |
| 1sdm | ADP | Kinesin heavy chain-like protein | / | 0.481 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.480 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.480 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.479 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.479 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.479 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.479 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.478 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.478 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.478 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.477 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.477 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.477 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.476 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.475 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.475 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.475 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.474 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.474 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.474 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.473 | |
| 4l4x | NDP | AmphI | / | 0.473 | |
| 5a3b | APR | SIR2 family protein | / | 0.473 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 1osv | CHC | Bile acid receptor | / | 0.472 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.472 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.471 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.470 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.469 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.468 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.468 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.467 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.467 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.466 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.466 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.466 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.465 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.465 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.465 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.465 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.465 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3cvu | FAD | RE11660p | / | 0.464 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.463 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.463 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.463 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.463 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.462 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.462 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.461 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 2hw1 | ANP | Ketohexokinase | / | 0.461 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.461 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.461 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.461 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.460 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.460 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.460 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.460 | |
| 4l8u | 9AZ | Serum albumin | / | 0.460 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.459 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.459 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.459 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.459 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.459 | |
| 3gob | HXX | DdmC | / | 0.459 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.459 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.459 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.459 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.458 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.458 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.458 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.458 | |
| 3cp9 | C19 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.458 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.458 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.458 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.457 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.457 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.457 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2y3r | TRK | TamL | / | 0.457 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.457 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.457 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.457 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.457 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 5doz | NDP | JamJ | / | 0.457 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.456 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.456 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.456 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.456 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.456 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.456 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.456 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.456 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.456 | |
| 3q92 | XNB | Ketohexokinase | / | 0.456 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.456 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.456 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.455 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.455 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.455 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.455 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.455 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.455 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.455 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.455 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.454 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.454 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.454 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.454 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.454 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.454 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.454 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.454 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.454 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.454 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.453 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.453 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.453 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.453 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.453 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.453 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.453 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.453 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.452 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.452 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.452 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.452 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4dja | FAD | (6-4) photolyase | / | 0.452 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.452 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.452 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.452 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.451 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.451 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 2y3s | TIR | TamL | / | 0.451 | |
| 3iaa | TYD | CalG2 | / | 0.451 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.451 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.451 | |
| 5ca1 | NZO | Tubulin beta-2 chain | / | 0.451 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.451 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.451 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.450 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.450 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1qy5 | NEC | Endoplasmin | / | 0.450 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.450 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.450 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2e07 | SAH | Diphthine synthase | / | 0.450 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.450 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.450 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.450 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.450 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.450 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.450 | |
| 3zuy | TCH | Transporter | / | 0.450 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.450 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 4o4f | ATP | Kinase | / | 0.450 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 1eio | GCH | Gastrotropin | / | 0.449 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.449 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.449 | |
| 2fyp | RDE | Endoplasmin | / | 0.449 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.449 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.449 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.449 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.449 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.449 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.449 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1c70 | L75 | Protease | / | 0.448 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.448 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.448 | |
| 1w5v | BE3 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 2ejz | SAH | Diphthine synthase | / | 0.448 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.448 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.448 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.448 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.448 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.448 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.448 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.447 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.447 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.447 | |
| 2p5c | SAH | Diphthine synthase | / | 0.447 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.447 | |
| 2wpx | ACO | Orf14 | / | 0.447 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.447 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.447 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.447 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.446 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.446 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.446 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.446 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.446 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.446 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.446 | |
| 3qai | XNN | Ketohexokinase | / | 0.446 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.446 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.446 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.446 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.446 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.446 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.445 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.445 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.445 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2f3k | RO1 | Protease | / | 0.445 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.445 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2owu | SAH | Diphthine synthase | / | 0.445 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.445 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.445 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.445 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.445 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.445 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.444 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1rkd | ADP | Ribokinase | / | 0.444 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.444 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.444 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.444 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.444 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.444 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 2k5t | COA | PanD regulatory factor | / | 0.444 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.444 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.444 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.444 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.444 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.444 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.444 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.444 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.444 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.444 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.444 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.444 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.444 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.444 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.444 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.444 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.444 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.443 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.443 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.443 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.443 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.443 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.443 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.443 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.443 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.443 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.443 | |
| 4kb9 | G79 | Protease | / | 0.443 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.443 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.442 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.442 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.442 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2cjp | VPR | Epoxide hydrolase | / | 0.442 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3lf0 | ATP | Nitrogen regulatory protein P-II | / | 0.442 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.442 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.442 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.442 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.442 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.441 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.441 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.441 | |
| 2p3b | 3TL | V-1 protease | / | 0.441 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.441 | |
| 2qi1 | MZ4 | Gag-Pol polyprotein | / | 0.441 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3iaf | TPP | Benzaldehyde lyase | / | 0.441 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.441 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.441 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.441 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4e2d | FMN | Dehydrogenase | / | 0.441 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4lb2 | DM5 | Serum albumin | / | 0.441 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.441 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.441 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.440 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.440 | |
| 2go4 | TUX | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.440 | |
| 2nnk | ROC | Protease | / | 0.440 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.440 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.440 | |
| 3dck | KVI | Protease | / | 0.440 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.440 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.440 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3nxe | 2NC | Protease | / | 0.440 | |
| 3o9d | K19 | Pol polyprotein | / | 0.440 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.440 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.440 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.440 |