Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.759 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.748 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.723 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.704 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.656 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.656 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.653 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.650 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.650 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.635 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.630 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.628 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.622 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.614 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.612 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.610 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.606 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.605 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.603 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.602 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.602 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.600 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.600 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.591 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.555 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.546 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.546 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.545 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.541 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.541 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.525 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.515 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.513 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.504 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.504 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.502 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.502 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.501 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.496 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.496 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.496 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.495 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.492 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.491 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.490 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.490 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.490 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.488 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.488 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.487 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.487 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.487 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4xr9 | NAD | CalS8 | / | 0.485 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.484 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.484 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.484 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.483 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.483 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.481 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.481 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.480 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.480 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.480 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.480 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.479 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.479 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.479 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.478 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.478 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.477 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.476 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.476 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.476 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.476 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.476 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.475 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.474 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.474 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.474 | |
| 1m9t | INE | Nitric oxide synthase, inducible | 1.14.13.39 | 0.473 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.473 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.473 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.473 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.473 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.473 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.472 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.472 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.472 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.471 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.470 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.470 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.470 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.470 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.470 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.470 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.469 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.469 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.469 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.469 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.468 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.468 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.467 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.467 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1fml | RTL | Retinol dehydratase | / | 0.466 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.466 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.466 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.466 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 4dpd | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.465 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.465 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.465 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.464 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.464 | |
| 2el0 | SAH | Diphthine synthase | / | 0.464 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.464 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.463 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.463 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.463 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.463 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.463 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4e2b | FMN | Dehydrogenase | / | 0.463 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.463 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.462 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.462 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.462 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.462 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.462 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.461 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.461 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4iqq | UMP | Thymidylate synthase | / | 0.461 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.461 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.460 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.460 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.460 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.460 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.460 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.460 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.459 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.459 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.459 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.458 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.458 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.458 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.458 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.458 | |
| 4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.458 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.458 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.457 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.457 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.457 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.457 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.457 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.457 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.456 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.456 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.456 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.456 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.455 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.455 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.455 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.455 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.455 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.455 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.454 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.454 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.454 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.454 | |
| 2pkl | DHT | Androgen receptor | / | 0.454 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.454 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.454 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.453 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.453 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.453 | |
| 1jmf | UMP | Thymidylate synthase | / | 0.453 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2y3r | TIR | TamL | / | 0.453 | |
| 2y4g | TIR | TamL | / | 0.453 | |
| 3cse | N22 | Uncharacterized protein | / | 0.453 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.453 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.453 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4qed | NAP | ElxO | / | 0.453 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.453 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.452 | |
| 1m9j | CLW | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.452 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.452 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3eai | 328 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.452 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.452 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.452 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.452 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.452 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.452 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.451 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.451 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.451 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.451 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.451 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4qen | SAH | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 | 2.1.1.43 | 0.451 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.451 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.450 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 2e17 | SAH | Diphthine synthase | / | 0.450 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.450 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.450 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.450 | |
| 3e7i | B2 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.450 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.450 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.450 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.450 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.450 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2bxm | IMN | Serum albumin | / | 0.449 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.449 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e68 | AT6 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.449 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.449 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.449 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4zm3 | PLP | Aminotransferase | / | 0.449 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.448 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.448 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.448 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.448 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.448 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.448 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.448 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.448 | |
| 3eej | 53R | Uncharacterized protein | / | 0.448 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.448 | |
| 3ggc | H26 | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.448 | |
| 3i53 | SAH | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.448 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 4e2d | FMN | Dehydrogenase | / | 0.448 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4gqe | 6KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.448 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.447 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.447 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.447 | |
| 3ebf | 332 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.447 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.447 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.447 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.447 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.447 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.447 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.447 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.447 | |
| 4hx5 | 19V | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.446 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.446 | |
| 2y3r | TRK | TamL | / | 0.446 | |
| 3dga | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.446 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.445 | |
| 1m9r | INE | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.445 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.445 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
| 1t79 | DHT | Androgen receptor | / | 0.445 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.445 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3n63 | XFN | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.445 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.445 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 4fvz | 4KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.445 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.445 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.444 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.444 | |
| 1nja | DCM | Thymidylate synthase | / | 0.444 | |
| 1njc | DCM | Thymidylate synthase | / | 0.444 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.444 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.444 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.444 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.444 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.444 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.444 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.444 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.444 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.443 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.443 | |
| 3eah | 327 | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.443 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.443 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.443 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.443 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4idp | GNP | Atlastin-1 | 3.6.5 | 0.443 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.443 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.443 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.442 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.442 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.442 | |
| 1vce | SAH | Diphthine synthase | / | 0.442 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.442 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.442 | |
| 4boe | CLR | Japanin | / | 0.442 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.442 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.442 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1bp0 | UMP | Thymidylate synthase | / | 0.441 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.441 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.441 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.441 | |
| 4bmp | FMN | Protein NrdI | / | 0.441 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.441 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.441 | |
| 4oey | DHT | Androgen receptor | / | 0.441 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.441 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.441 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.440 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.440 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.440 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.440 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.440 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ex8 | AIF | Riboflavin biosynthesis protein RibD | 1.1.1.193 | 0.440 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.440 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 3pvt | 3HC | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.440 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.440 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.440 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.440 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 | |
| 4y1b | NAP | AntE | / | 0.440 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.440 |