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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4i02CMPcAMP-activated global transcriptional regulator CRP

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4i02CMPcAMP-activated global transcriptional regulator CRP/1.000
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.614
2oz6CMPCyclic AMP receptor-like protein/0.539
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.535
1hw5CMPcAMP-activated global transcriptional regulator CRP/0.525
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.523
1g6nCMPcAMP-activated global transcriptional regulator CRP/0.504
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.503
4nxvGDPMitochondrial dynamics protein MID51/0.503
1cgpCMPcAMP-activated global transcriptional regulator CRP/0.502
3ryrCMPcAMP-activated global transcriptional regulator CRP/0.501
4i0bCMPcAMP-activated global transcriptional regulator CRP/0.501
1upw444Oxysterols receptor LXR-beta/0.499
3ctyFADProbable thioredoxin reductase/0.497
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.497
4a6bQG8Gag-Pol polyprotein3.4.23.160.491
2gzwCMPcAMP-activated global transcriptional regulator CRP/0.490
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.490
2fznFADBifunctional protein PutA1.5.5.20.488
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.487
3nwxKVSGag-Pol polyprotein3.4.23.160.487
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.486
1tj2FADBifunctional protein PutA1.5.5.20.485
3f03FMNPentaerythritol tetranitrate reductase/0.485
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.484
2y05NAPProstaglandin reductase 1/0.484
3dmeFADPutative conserved exported protein/0.484
1i5zCMPcAMP-activated global transcriptional regulator CRP/0.483
2vbdV10Isopenicillin N synthase1.21.3.10.483
1gqtACPRibokinase/0.482
2g5cNADPrephenate dehydrogenase/0.482
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.482
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.482
1nytNAPShikimate dehydrogenase (NADP(+))/0.481
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.481
1yqxNAPSinapyl alcohol dehydrogenase/0.480
1ruoCMPcAMP-activated global transcriptional regulator CRP/0.479
2qo9ANPEphrin type-A receptor 32.7.10.10.479
3rypCMPcAMP-activated global transcriptional regulator CRP/0.479
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.479
4g2fC07Ephrin type-A receptor 32.7.10.10.478
4l9kEHFSerum albumin/0.478
4yagNAIC alpha-dehydrogenase/0.478
5dp2NAPCurF/0.478
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.477
3s1dZIRCytokinin dehydrogenase 11.5.99.120.477
3w0iO11Vitamin D3 receptor/0.477
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.476
4dh60KNBeta-secretase 13.4.23.460.476
4gr1FADGlutathione reductase, mitochondrial1.8.1.70.476
4tuvCPZCytochrome P450 1191.140.476
2ev9NAPShikimate dehydrogenase (NADP(+))/0.475
3vt7VDXVitamin D3 receptor/0.475
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.474
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.474
3cukFADD-amino-acid oxidase1.4.3.30.473
4i09CMPcAMP-activated global transcriptional regulator CRP/0.473
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.473
4nh82LCHeat shock protein HSP 90-alpha/0.473
1bwlFMNNADPH dehydrogenase 11.6.99.10.472
1vjy460TGF-beta receptor type-12.7.11.300.472
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.471
2givACOHistone acetyltransferase KAT8/0.471
2hamC33Vitamin D3 receptor/0.471
3nxe2NCProtease/0.471
3to6LYS_CMCHistone acetyltransferase ESA1/0.471
4jbiNDPAlcohol dehydrogenase (Zinc)/0.471
1u3cFADCryptochrome-1/0.470
3drcMTXDihydrofolate reductase1.5.1.30.470
4jq9FADDihydrolipoyl dehydrogenase/0.470
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.469
3ic9FADPutative dihydrolipoamide dehydrogenase/0.469
3q44D50M1 family aminopeptidase3.4.110.469
1k6cMK1Gag-Pol polyprotein3.4.23.160.468
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.468
1yqdNAPSinapyl alcohol dehydrogenase/0.468
2uxpCLMHTH-type transcriptional regulator TtgR/0.468
4hzfCMPcAMP-activated global transcriptional regulator CRP/0.468
1g4tFTPThiamine-phosphate synthase/0.467
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1sn5T3Transthyretin/0.467
1tj1FADBifunctional protein PutA1.5.5.20.467
2ou2ACOHistone acetyltransferase KAT5/0.467
2xhd7T9Glutamate receptor 2/0.467
3gw9VNILanosterol 14-alpha-demethylase/0.467
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
2hk9NAPShikimate dehydrogenase (NADP(+))/0.466
3hv5R24Mitogen-activated protein kinase 14/0.466
3uylTYDProbable NDP-rhamnosyltransferase/0.466
4n9iPCGCatabolite expression activator/0.466
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.466
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.466
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
1h50FMNPentaerythritol tetranitrate reductase/0.465
1lluNADAlcohol dehydrogenase/0.465
2y0mACOHistone acetyltransferase KAT8/0.465
3p62FMNPentaerythritol tetranitrate reductase/0.465
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.465
4i0aCMPcAMP-activated global transcriptional regulator CRP/0.465
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.465
1j3kNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
2hcdBIVVitamin D3 receptor A/0.464
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2npaMMBPeroxisome proliferator-activated receptor alpha/0.464
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.464
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.464
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.464
1h63FMNPentaerythritol tetranitrate reductase/0.463
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.463
3uteFADUDP-galactopyranose mutase/0.463
1f8sFADL-amino-acid oxidase1.4.3.20.462
2gjlFMNNitronate monooxygenase1.13.12.160.462
3atzFMNProstaglandin F2a synthase/0.462
3bbrBHYGlutamate receptor 2/0.462
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
1hb3SCVIsopenicillin N synthase1.21.3.10.461
2xgs44PUncharacterized protein/0.461
3b70NAPEnoyl reductase LovC10.461
3icrFADCoenzyme A disulfide reductase/0.461
3ukoNADAlcohol dehydrogenase class-3/0.461
1bwsNDPGDP-L-fucose synthase/0.460
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1txiTX5Vitamin D3 receptor/0.460
2ftoCB3Thymidylate synthase/0.460
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.460
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2y6fM9FIsopenicillin N synthase1.21.3.10.460
3bg7FADPyranose 2-oxidase/0.460
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
1e3wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.459
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.459
2a94AP0L-lactate dehydrogenase1.1.1.270.459
2abbFMNPentaerythritol tetranitrate reductase/0.459
2bi4NADLactaldehyde reductase1.1.1.770.459
2po7CHDFerrochelatase, mitochondrial4.99.1.10.459
3mk6ACOPantothenate kinase 32.7.1.330.459
4a6cQG9Gag-Pol polyprotein3.4.23.160.459
4ambDUDPutative glycosyl transferase/0.459
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.458
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.458
2iviACWIsopenicillin N synthase1.21.3.10.458
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
3gbuATPUncharacterized sugar kinase PH14592.7.10.458
3vt3VDXVitamin D3 receptor/0.458
4dymIYZActivin receptor type-12.7.11.300.458
4jicFMNGTN Reductase/0.458
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.458
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.458
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.457
2h55DZ8Heat shock protein HSP 90-alpha/0.457
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.457
2ykeYKEHeat shock protein HSP 90-alpha/0.457
2zl9VDAVitamin D3 receptor/0.457
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3tz3B36Acetyl-CoA carboxylase/0.457
3vt9YI4Vitamin D3 receptor/0.457
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.457
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.457
1culFOKAdenylate cyclase type 2/0.456
1culFOKAdenylate cyclase type 5/0.456
1drhNAPDihydrofolate reductase1.5.1.30.456
1s19MC9Vitamin D3 receptor/0.456
1u3dFADCryptochrome-1/0.456
3bgcLJHGag-Pol polyprotein3.4.23.160.456
3lqfNADGalactitol dehydrogenase/0.456
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.456
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.456
4dieC5PCytidylate kinase/0.456
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.456
4ji91M3Tyrosine-protein kinase JAK2/0.456
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
4ntcFADThioredoxin reductase gliT/0.456
4qgiROCGag-Pol polyprotein3.4.23.160.456
4u8iFDAUDP-galactopyranose mutase/0.456
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.455
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.455
2vkmBSDBeta-secretase 13.4.23.460.455
3kpkFADSulfide-quinone reductase/0.455
3uwqU5POrotidine 5'-phosphate decarboxylase/0.455
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.455
4wkqIREEpidermal growth factor receptor2.7.10.10.455
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.455
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2a1y5GPGMP reductase/0.454
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.454
2cy0NAPShikimate dehydrogenase (NADP(+))/0.454
2gv8NDPThiol-specific monooxygenase1.14.130.454
2pobGW4Peroxisome proliferator-activated receptor gamma/0.454
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.454
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.454
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.454
3uceNDPDehydrogenase/0.454
3vt8YI3Vitamin D3 receptor/0.454
4bb3KKAIsopenicillin N synthase1.21.3.10.454
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.454
4iteTEYVitamin D3 receptor/0.454
4uyf73BBromodomain-containing protein 2/0.454
5cnnANPEpidermal growth factor receptor2.7.10.10.454
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.453
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1jpaANPEphrin type-B receptor 22.7.10.10.453
1mjbACOHistone acetyltransferase ESA1/0.453
2c0cNAPProstaglandin reductase 310.453
2dteNAIGlucose 1-dehydrogenase related protein/0.453
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.453
2hb7O1CVitamin D3 receptor/0.453
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.453
2yyuC5POrotidine 5'-phosphate decarboxylase/0.453
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.453
3grsFADGlutathione reductase, mitochondrial1.8.1.70.453
3h3sH15Collagen type IV alpha-3-binding protein/0.453
3hz5Z64Heat shock protein HSP 90-alpha/0.453
4dnaFADProbable glutathione reductase/0.453
4e5yNDPGDP-L-fucose synthase1.1.1.2710.453
4fhh0U3Vitamin D3 receptor A/0.453
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.453
4rupH97Vitamin D3 receptor A/0.453
1cf3FADGlucose oxidase1.1.3.40.452
1db1VDXVitamin D3 receptor/0.452
1hb1OCVIsopenicillin N synthase1.21.3.10.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1lf3EH5Plasmepsin-23.4.23.390.452
1xe65FPPlasmepsin-23.4.23.390.452
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
4a99FADTetX family tetracycline inactivation enzyme/0.452
4opiFDAConserved Archaeal protein/0.452
1c1dNAIPhenylalanine dehydrogenase/0.451
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1e3eNAIAlcohol dehydrogenase 41.1.1.10.451
1fm9570Peroxisome proliferator-activated receptor gamma/0.451
1graFADGlutathione reductase, mitochondrial1.8.1.70.451
1k6tXN1Gag-Pol polyprotein3.4.23.160.451
1rm3NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.451
2fzwNADAlcohol dehydrogenase class-31.1.1.10.451
2harOCCVitamin D3 receptor/0.451
2hc4VDXVitamin D3 receptor A/0.451
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.451
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.451
3tvuB37Acetyl-CoA carboxylase/0.451
4a8v2ANMajor pollen allergen Bet v 1-J/0.451
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4ki8ADP60 kDa chaperonin/0.451
4nxxGDPMitochondrial dynamics protein MID51/0.451
1bsvNDPGDP-L-fucose synthase/0.450
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.450
1ie3NADMalate dehydrogenase/0.450
1ipeNDPTropinone reductase 21.1.1.2360.450
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.450
2rg5279Mitogen-activated protein kinase 14/0.450
2wsbNADGalactitol dehydrogenase/0.450
3a783EVVitamin D3 receptor/0.450
3itjFADThioredoxin reductase 11.8.1.90.450
3oibFDAPutative acyl-CoA dehydrogenase/0.450
3slkNDPPolyketide synthase extender module 2/0.450
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.450
4g3jVNTLanosterol 14-alpha-demethylase/0.450
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.450
4o2bLOCTubulin beta-2B chain/0.450
5e8wSTUTGF-beta receptor type-12.7.11.300.450
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.450
5jlaNADPutative short-chain dehydrogenase/reductase/0.450
1fy7COAHistone acetyltransferase ESA1/0.449
1ia1NDPDihydrofolate reductase1.5.1.30.449
1uyePU9Heat shock protein HSP 90-alpha/0.449
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2aznNAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase/0.449
2d29FADAcyl-CoA dehydrogenase/0.449
2fzmFADBifunctional protein PutA1.5.5.20.449
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.449
2jk6FADTrypanothione reductase/0.449
2vprTDCTetracycline repressor protein class H/0.449
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
3jynNDPQuinone oxidoreductase/0.449
3oqkS52Renin3.4.23.150.449
3tnlNADShikimate dehydrogenase (NADP(+))/0.449
3zuyTCHTransporter/0.449
4e5kNADPhosphonate dehydrogenase1.20.1.10.449
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.449
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.449
4nxuADPMitochondrial dynamics protein MID51/0.449
4q71FADBifunctional protein PutA/0.449
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.449
1greFADGlutathione reductase, mitochondrial1.8.1.70.448
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.448
1m17AQ4Epidermal growth factor receptor2.7.10.10.448
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
2ca0PXICytochrome P450 monooxygenase PikC/0.448
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.448
2qu6857Vascular endothelial growth factor receptor 22.7.10.10.448
2vx07X7Ephrin type-B receptor 42.7.10.10.448
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.448
2zlaVDBVitamin D3 receptor/0.448
3hwrNDP2-dehydropantoate 2-reductase/0.448
3triNAPPyrroline-5-carboxylate reductase/0.448
3up0D7SaceDAF-12/0.448
3vt5YI2Vitamin D3 receptor/0.448
3w0yDS4Vitamin D3 receptor/0.448
3w5rLOAVitamin D3 receptor/0.448
4g1z0VPVitamin D3 receptor A/0.448
4gl4NAIAlcohol dehydrogenase class-3/0.448
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
5dbgNADIridoid synthase1.3.1.990.448
1bk0ACVIsopenicillin N synthase1.21.3.10.447
1dr3TAPDihydrofolate reductase1.5.1.30.447
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.447
1qvnFRIInterleukin-2/0.447
1rx1NAPDihydrofolate reductase1.5.1.30.447
2a87FADThioredoxin reductase1.8.1.90.447
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.447
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.447
3ik6HCZGlutamate receptor 2/0.447
3ingNDPHomoserine dehydrogenase related protein/0.447
3n0bFADFlavin-dependent thymidylate synthase2.1.1.1480.447
3w5tLHPVitamin D3 receptor/0.447
4ap3FADSteroid monooxygenase/0.447
4b7xNAPProbable oxidoreductase/0.447
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4xq9NADHomospermidine synthase2.5.1.440.447
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.447
1ma0NADAlcohol dehydrogenase class-31.1.1.10.446
1rjkVDZVitamin D3 receptor/0.446
1rk3VDXVitamin D3 receptor/0.446
1tehNADAlcohol dehydrogenase class-31.1.1.10.446
1zrzBI1Protein kinase C iota type2.7.11.130.446
2a92NAIL-lactate dehydrogenase/0.446
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.446
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.446
2ebaFADPutative glutaryl-CoA dehydrogenase/0.446
2gs7ANPEpidermal growth factor receptor2.7.10.10.446
2iyaZIOOleandomycin glycosyltransferase/0.446
2rkvZBATrichothecene 3-O-acetyltransferase/0.446
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.446
3atyFMNProstaglandin F2a synthase/0.446
3crzFADFerredoxin--NADP+ reductase/0.446
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3kb6NADD-lactate dehydrogenase/0.446
3nl6TPSUncharacterized protein/0.446
3w0aDS5Vitamin D3 receptor/0.446
4b7sQLECytochrome P450 monooxygenase PikC/0.446
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.446
4l4xNDPAmphI/0.446
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.445
1pr9NAPL-xylulose reductase1.1.1.100.445
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.445
1tl7FOKAdenylate cyclase type 2/0.445
1tl7FOKAdenylate cyclase type 5/0.445
1w2xRCPAcetyl-CoA carboxylase/0.445
1w4zNAPPutative ketoacyl reductase1.3.10.445
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.445
2gr1FADFerredoxin reductase/0.445
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.445
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.445
2wotZZGTGF-beta receptor type-12.7.11.300.445
2xaaNADSecondary alcohol dehydrogenase/0.445
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.445
3e2sFADBifunctional protein PutA1.5.5.20.445
3hazFADBifunctional protein PutA/0.445
3kccCMPcAMP-activated global transcriptional regulator CRP/0.445
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
3oqfS51Renin3.4.23.150.445
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.445
3r9uFADThioredoxin reductase/0.445
3t3c017Gag-Pol polyprotein3.4.23.160.445
3vtdTKDVitamin D3 receptor/0.445
4g7gVFVLanosterol 14-alpha-demethylase/0.445
4yaiNAIC alpha-dehydrogenase/0.445
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.445
1bygSTUTyrosine-protein kinase CSK/0.444
1c2tGARPhosphoribosylglycinamide formyltransferase/0.444
1cjkFOKAdenylate cyclase type 2/0.444
1cjkFOKAdenylate cyclase type 5/0.444
1cjtFOKAdenylate cyclase type 2/0.444
1cjtFOKAdenylate cyclase type 5/0.444
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.444
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.444
1m13HYFNuclear receptor subfamily 1 group I member 2/0.444
1mjaCOAHistone acetyltransferase ESA1/0.444
1qorNDPQuinone oxidoreductase 1/0.444
1uyfPU1Heat shock protein HSP 90-alpha/0.444
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.444
2ardFDAFlavin-dependent tryptophan halogenase PrnA1.14.19.90.444
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.444
2hqmFADGlutathione reductase1.8.1.70.444
2itzIREEpidermal growth factor receptor2.7.10.10.444
2uxoTACHTH-type transcriptional regulator TtgR/0.444
2vn0TDZCytochrome P450 2C8/0.444
3d3wNAPL-xylulose reductase1.1.1.100.444
3k4nFADPyranose 2-oxidase/0.444
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
3qwbNDPProbable quinone oxidoreductase1.6.5.50.444
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
3vrvYSDVitamin D3 receptor/0.444
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.444
4hjoAQ4Epidermal growth factor receptor2.7.10.10.444
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.444
4hwkNAPSepiapterin reductase1.1.1.1530.444
4i22IREEpidermal growth factor receptor2.7.10.10.444
4ia3BIVVitamin D3 receptor A/0.444
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.444
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1knrFADL-aspartate oxidase1.4.3.160.443
1mzs6693-oxoacyl-[acyl-carrier-protein] synthase 3/0.443
1pdhFASp-hydroxybenzoate hydroxylase/0.443
1rkhVD2Vitamin D3 receptor/0.443
1rneC60Renin3.4.23.150.443
1zz2B11Mitogen-activated protein kinase 14/0.443
2ad5ADPCTP synthase/0.443
2ahrNAPPyrroline-5-carboxylate reductase/0.443
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.443
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
2pg0FADAcyl-CoA dehydrogenase/0.443
3ac1KZITyrosine-protein kinase Lck2.7.10.20.443
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.443
3gwfFADCyclohexanone monooxygenase/0.443
3kpzZNEVitamin D3 receptor/0.443
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
3zpsEQMGag-Pol polyprotein3.4.23.160.443
4enhFVXCholesterol 24-hydroxylase/0.443
4ewo996Beta-secretase 13.4.23.460.443
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4i01CMPcAMP-activated global transcriptional regulator CRP/0.443
4i5vB4PDiadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2/0.443
4q73FADBifunctional protein PutA/0.443
4qi5FADCellobiose dehydrogenase/0.443
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.443
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
1blzACVIsopenicillin N synthase1.21.3.10.442
1icqFMN12-oxophytodienoate reductase 11.3.1.420.442
1iyzNDPProbable quinone oxidoreductase/0.442
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1k6vXN2Gag-Pol polyprotein3.4.23.160.442
1msmJE2Gag-Pol polyprotein3.4.23.160.442
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.442
1nvtNAPShikimate dehydrogenase (NADP(+))/0.442
1w6hTITPlasmepsin-23.4.23.390.442
2c29NAPDihydroflavonol 4-reductase/0.442
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.442
2hasC3OVitamin D3 receptor/0.442
2hb8MVDVitamin D3 receptor/0.442
2jn3JN3Fatty acid-binding protein, liver/0.442
2vbpVB1Isopenicillin N synthase1.21.3.10.442
2wbaFADTrypanothione reductase1.8.1.120.442
2wouZZFTGF-beta receptor type-12.7.11.300.442
2y60M8FIsopenicillin N synthase1.21.3.10.442
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3il1B5DGlutamate receptor 2/0.442
3nx4NAPPutative oxidoreductase/0.442
3own3OWRenin3.4.23.150.442
3p82FMNPentaerythritol tetranitrate reductase/0.442
3pm9FADPutative oxidoreductase/0.442
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.442
3w0jT08Vitamin D3 receptor/0.442
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.442
4jq8KJ8Epidermal growth factor receptor2.7.10.10.442
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.442
1g1aNADdTDP-glucose 4,6-dehydratase/0.441
1s0zEB1Vitamin D3 receptor/0.441
1sbyNADAlcohol dehydrogenase1.1.1.10.441
1uyhPU0Heat shock protein HSP 90-alpha/0.441
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.441
2o4jVD4Vitamin D3 receptor/0.441
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.441
2q7vFADThioredoxin reductase/0.441
2xlsFADPutative flavin-containing monooxygenase/0.441
2xveFADPutative flavin-containing monooxygenase/0.441
2ym2NAPPhenylacetone monooxygenase1.14.13.920.441
2z3uCRRCytochrome P450/0.441
2zb3NDPProstaglandin reductase 21.3.1.480.441
3cosNADAlcohol dehydrogenase 41.1.1.10.441
3fcjFADNitroalkane oxidase1.7.3.10.441
3i7eDJRGag-Pol polyprotein/0.441
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.441
3nxxNDPDihydrofolate reductase1.5.1.30.441
3r5zF42Uncharacterized protein/0.441
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.441
3vt45YIVitamin D3 receptor/0.441
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
3zkyWT4Isopenicillin N synthase1.21.3.10.441
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.441
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.441
4ejmNAPPutative zinc-binding dehydrogenase/0.441
4gk2L66Ephrin type-A receptor 32.7.10.10.441
4kba1QMCasein kinase I isoform delta2.7.11.10.441
4n57ADPAPH(2'')-Id/0.441
4nxwADPMitochondrial dynamics protein MID51/0.441
4o701QKBromodomain-containing protein 4/0.441
4ruoBIVVitamin D3 receptor A/0.441
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.441
4ww0ADPATP-dependent zinc metalloprotease FtsH/0.441
4yryFADGlutamate synthase, beta subunit/0.441
5dbvCOAAldehyde Dehydrogenase/0.441
1mp0NADAlcohol dehydrogenase class-31.1.1.10.440
1nf7RVPInosine-5'-monophosphate dehydrogenase 2/0.440
1rfvADPPyridoxal kinase2.7.1.350.440
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.950.440
2i4qUA4Renin3.4.23.150.440
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2owuSAHDiphthine synthase/0.440
2r0pK2CPutative FAD-monooxygenase/0.440
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2v6oFADThioredoxin glutathione reductase/0.440
3dr1C5DVitamin D3 receptor A/0.440
3kybFADUDP-galactopyranose mutase5.4.99.90.440
3nwq2NCGag-Pol polyprotein3.4.23.160.440
3oom507Activin receptor type-12.7.11.300.440
3rf7NADIron-containing alcohol dehydrogenase/0.440
3w0c6DSVitamin D3 receptor/0.440
3w32W32Epidermal growth factor receptor2.7.10.10.440
3zpuM8BGag-Pol polyprotein3.4.23.160.440
4b7dQLECytochrome P450 monooxygenase PikC/0.440
4c58824Cyclin-G-associated kinase2.7.11.10.440
4dbzNDPPutative ketoacyl reductase1.3.10.440
4dplNAPMalonyl-CoA reductase1.2.1.750.440
4e5j581Polymerase acidic protein/0.440
4o1mNADEnoyl-acyl carrier reductase/0.440
5lc1NADL-threonine 3-dehydrogenase/0.440