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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.301.000
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.527
4bfxZVXPantothenate kinase2.7.1.330.521
4krs1SXTankyrase-12.4.2.300.518
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.507
4bfvZVVPantothenate kinase2.7.1.330.506
1x1aSAMC-20 methyltransferase/0.497
3tlc7MDMicrocin C7 self-immunity protein MccF/0.495
4tkg09LTankyrase-22.4.2.300.494
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.493
4bftZVTPantothenate kinase2.7.1.330.493
4bfwZVWPantothenate kinase2.7.1.330.493
2ejzSAHDiphthine synthase/0.492
3ekuCY9Actin-5C/0.490
2g1n1IGRenin3.4.23.150.489
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.489
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.488
4pnrG18Tankyrase-22.4.2.300.488
3u9y09LTankyrase-22.4.2.300.487
3v2uATPProtein GAL3/0.487
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.487
4bfzZVZPantothenate kinase2.7.1.330.485
5jhnSAMHistone-lysine N-methyltransferase EHMT2/0.483
1tj0FADBifunctional protein PutA1.5.5.20.481
3fp0FP015-O-acetyltransferase/0.481
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.480
2zitNADExotoxin A2.4.2.360.479
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.479
2g1r3IGRenin3.4.23.150.478
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.478
4bjcRPBTankyrase-22.4.2.300.478
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.478
3aosJH2Hemolymph juvenile hormone binding protein/0.477
3fhxPXLPyridoxal kinase2.7.1.350.477
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.477
4bj9UHBTankyrase-22.4.2.300.477
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.476
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.475
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.475
4b2gV1NUncharacterized protein/0.475
4jlm1NNDeoxycytidine kinase2.7.1.740.475
4yaoFMNNADPH--cytochrome P450 reductase/0.475
1d3dBZTProthrombin3.4.21.50.474
1xvaSAMGlycine N-methyltransferase2.1.1.200.474
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.474
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.473
1cs4FOKAdenylate cyclase type 2/0.472
1cs4FOKAdenylate cyclase type 5/0.472
2geuCOKPantothenate kinase2.7.1.330.472
3zkyWT4Isopenicillin N synthase1.21.3.10.472
4bb3KKAIsopenicillin N synthase1.21.3.10.472
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.472
1ja1FMNNADPH--cytochrome P450 reductase/0.471
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.471
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.471
2g9rG27Glycogen phosphorylase, muscle form2.4.1.10.471
2xveFADPutative flavin-containing monooxygenase/0.471
3h3qH13Collagen type IV alpha-3-binding protein/0.471
4bfsZVSPantothenate kinase2.7.1.330.471
5irnADPNucleotide binding oligomerization domain containing 2/0.471
1h60STRPentaerythritol tetranitrate reductase/0.470
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.470
4e2yJHZMethyltransferase/0.470
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.470
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.469
1xk9P34Exotoxin A2.4.2.360.469
2g1s4IGRenin3.4.23.150.469
2g1y5IGRenin3.4.23.150.469
2h8xFMNXenA/0.469
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3h3t16HCollagen type IV alpha-3-binding protein/0.469
4esoNAPPutative oxidoreductase/0.469
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.469
1dr3TAPDihydrofolate reductase1.5.1.30.468
1pq944BOxysterols receptor LXR-beta/0.468
3qe2FMNNADPH--cytochrome P450 reductase/0.468
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.468
4tjy3GNTankyrase-22.4.2.300.468
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.467
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.467
3pkbY16Methionine aminopeptidase 2/0.467
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.467
4j3mAJ8Tankyrase-22.4.2.300.467
2il2LIXRenin3.4.23.150.465
2w6zL21Biotin carboxylase6.3.4.140.465
3h3r14HCollagen type IV alpha-3-binding protein/0.465
4zowCLMMultidrug transporter MdfA/0.465
1culFOKAdenylate cyclase type 2/0.464
1culFOKAdenylate cyclase type 5/0.464
1h63FMNPentaerythritol tetranitrate reductase/0.464
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.464
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.464
1p0pBCHCholinesterase3.1.1.80.464
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.464
2iko7IGRenin3.4.23.150.464
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.464
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.464
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.463
2cekN8TAcetylcholinesterase3.1.1.70.463
2dxwSAHDiphthine synthase/0.463
2p6kSAHDiphthine synthase/0.463
3hl0NADMaleylacetate reductase/0.463
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.463
3vw7VPXProteinase-activated receptor 1/0.463
2bn4FMNNADPH--cytochrome P450 reductase/0.462
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.462
2g247IGRenin3.4.23.150.462
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.462
4bfyZVYPantothenate kinase2.7.1.330.462
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.462
1dtpAPUDiphtheria toxin/0.461
1eveE20Acetylcholinesterase3.1.1.70.461
2gevCOKPantothenate kinase2.7.1.330.461
2ok8FADFerredoxin--NADP reductase, apicoplast/0.461
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.461
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3eksCY9Actin-5C/0.461
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.461
1ja0FMNNADPH--cytochrome P450 reductase/0.460
2zcvNDPQuinone oxidoreductase 21.6.5.20.460
3b8hNADExotoxin A2.4.2.360.460
3h3sH15Collagen type IV alpha-3-binding protein/0.460
3u8l09QAcetylcholine-binding protein/0.460
3oeeANPATP synthase subunit alpha, mitochondrial/0.459
3oeeANPATP synthase subunit beta, mitochondrial3.6.3.140.459
3ojxFMNNADPH--cytochrome P450 reductase/0.459
3zc3FADFerredoxin--NADP reductase1.18.1.20.459
4acxS8ZBeta-secretase 13.4.23.460.459
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.459
1dr3HBIDihydrofolate reductase1.5.1.30.458
1rzuADPGlycogen synthase 12.4.1.210.458
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.458
2abaSTRPentaerythritol tetranitrate reductase/0.458
2e8sSAHDiphthine synthase/0.458
2ikuLIYRenin3.4.23.150.458
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.458
3ziuLSSLeucyl-tRNA synthetase/0.458
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.458
1pqc444Oxysterols receptor LXR-beta/0.457
2rfiSAHHistone-lysine N-methyltransferase EHMT1/0.457
3af0GDPPantothenate kinase2.7.1.330.457
3b1dPLSBetaC-S lyase/0.457
3bk2U5PRibonuclease J/0.457
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.457
4loi1YCStimulator of interferon genes protein/0.457
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.457
1h8hATPATP synthase subunit alpha, mitochondrial/0.456
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.456
1hzzNAPNAD(P) transhydrogenase subunit beta1.6.1.20.456
1odcA8BAcetylcholinesterase3.1.1.70.456
2ea4F79Methionine aminopeptidase 2/0.456
2fhnBNIAvidin-related protein 4/5/0.456
2w6qOA5Biotin carboxylase6.3.4.140.456
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.456
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.456
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
2eh5SAHDiphthine synthase/0.455
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.455
2ym2NAPPhenylacetone monooxygenase1.14.13.920.455
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.455
3junAKDPhenazine biosynthesis protein A/B/0.455
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.455
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.455
3vydVYDRenin3.4.23.150.455
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.455
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.455
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.455
1e0jANPDNA primase/helicase2.7.70.454
1ta6177Prothrombin3.4.21.50.454
2g21L1BRenin3.4.23.150.454
2hldANPATP synthase subunit alpha, mitochondrial/0.454
2hldANPATP synthase subunit beta, mitochondrial3.6.3.140.454
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.454
2x9dITCTetracycline repressor protein class D/0.454
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.454
3arvSAUChitinase A/0.454
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.454
5c1mCLRMu-type opioid receptor/0.454
5dsyUHBPoly [ADP-ribose] polymerase 22.4.2.300.454
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.453
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.453
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1t2cNAIL-lactate dehydrogenase1.1.1.270.453
2fznFADBifunctional protein PutA1.5.5.20.453
2gtbAZPOrf1ab polyprotein/0.453
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.453
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.453
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.453
4an4DUDPutative glycosyl transferase/0.453
4bjbP34Tankyrase-22.4.2.300.453
4k6fNAPPutative Acetoacetyl-CoA reductase/0.453
1gky5GPGuanylate kinase2.7.4.80.452
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1ia3TQ5Dihydrofolate reductase1.5.1.30.452
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.452
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.452
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.452
3swcSAHHistone-lysine N-methyltransferase EHMT1/0.452
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.452
4ead0NPThymidine phosphorylase2.4.2.40.452
4fse0VABeta-secretase 13.4.23.460.452
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.452
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.452
4n3l2FNProthrombin3.4.21.50.452
4uthFMNXenobiotic reductase/0.452
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.451
1h50FMNPentaerythritol tetranitrate reductase/0.451
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.451
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.451
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.451
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.451
1ve3SAMUncharacterized protein/0.451
1yryMSGPurine nucleoside phosphorylase2.4.2.10.451
2a5kAZPReplicase polyprotein 1ab3.4.220.451
2jb4A14Isopenicillin N synthase1.21.3.10.451
2pncCLUPrimary amine oxidase, liver isozyme/0.451
3bj7COADiamine acetyltransferase 1/0.451
3fhxPLPPyridoxal kinase2.7.1.350.451
3go4SAHUncharacterized protein/0.451
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.451
3qwc98PProthrombin3.4.21.50.451
3vg10GTBeta-secretase 13.4.23.460.451
4araC56Acetylcholinesterase3.1.1.70.451
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.451
1ecb5GPAmidophosphoribosyltransferase/0.450
1hb3SCVIsopenicillin N synthase1.21.3.10.450
1hk5T44Serum albumin/0.450
1rd4L08Integrin alpha-L/0.450
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.450
1x1dSAHC-20 methyltransferase/0.450
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.450
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
2emrSAHDiphthine synthase/0.450
2iviACWIsopenicillin N synthase1.21.3.10.450
2jgsBTNAvidin/0.450
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.450
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3ojwFMNNADPH--cytochrome P450 reductase/0.450
3oqkS52Renin3.4.23.150.450
3vt9YI4Vitamin D3 receptor/0.450
3vucHHERenin3.4.23.150.450
4b1rITCTetracycline repressor protein class D/0.450
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4ise1FWGlucokinase2.7.1.20.450
4q71FADBifunctional protein PutA/0.450
4yp12BAStimulator of interferon genes protein/0.450
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.450
1hb1OCVIsopenicillin N synthase1.21.3.10.449
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.449
1qjfACSIsopenicillin N synthase1.21.3.10.449
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.449
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.449
2a94AP0L-lactate dehydrogenase1.1.1.270.449
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.449
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.449
2vkeTACTetracycline repressor protein class D/0.449
3abxRCBGlucanase/0.449
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3fpdSAHHistone-lysine N-methyltransferase EHMT1/0.449
3g5mFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
3juqAKDPhenazine biosynthesis protein A/B/0.449
3l67FMNXenobiotic reductase/0.449
3qgi33FGenome polyprotein2.7.7.480.449
3sff0DIHistone deacetylase 83.5.1.980.449
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.449
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.449
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.449
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.449
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.449
4fizCUE17beta-hydroxysteroid dehydrogenase/0.449
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.449
4kbyC2EStimulator of interferon genes protein/0.449
1f20FADNitric oxide synthase, brain1.14.13.390.448
1jumBERHTH-type transcriptional regulator QacR/0.448
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.448
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.448
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.448
1x1bSAHC-20 methyltransferase/0.448
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.448
2emuSAHDiphthine synthase/0.448
2g8yNADHydroxycarboxylate dehydrogenase B/0.448
2idkC2FGlycine N-methyltransferase2.1.1.200.448
2vprTDCTetracycline repressor protein class H/0.448
2w6oOA3Biotin carboxylase6.3.4.140.448
2xlrFADPutative flavin-containing monooxygenase/0.448
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.448
3fktSIIBeta-secretase 13.4.23.460.448
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.448
3mj4URMUDP-galactopyranose mutase/0.448
3vt7VDXVitamin D3 receptor/0.448
3zeiAWHO-acetylserine sulfhydrylase/0.448
4i13FOLDihydrofolate reductase1.5.1.30.448
4m83ERYOleandomycin glycosyltransferase2.4.10.448
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.448
4v2gITCTetracycline repressor protein class D/0.448
4xguADPPutative pachytene checkpoint protein 2/0.448
5fd8A5APutative carboxypeptidase yocD/0.448
1bk0ACVIsopenicillin N synthase1.21.3.10.447
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1rneC60Renin3.4.23.150.447
1swpBTQStreptavidin/0.447
1zrb062Prothrombin3.4.21.50.447
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.447
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2d29FADAcyl-CoA dehydrogenase/0.447
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.447
2i4qUA4Renin3.4.23.150.447
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.447
2zsdCOAPantothenate kinase2.7.1.330.447
3b7dCNIGlutamate receptor 2/0.447
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.447
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.447
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.447
3g70A5TRenin3.4.23.150.447
3nmpPYVAbscisic acid receptor PYL2/0.447
3qt62P0Mevalonate diphosphate decarboxylase/0.447
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.447
3to3ATPPetrobactin biosynthesis protein AsbB/0.447
4a83DXCMajor pollen allergen Bet v 1-A/0.447
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.447
4dc0NDPPutative ketoacyl reductase1.3.10.447
4j491J1Uncharacterized protein/0.447
4klaCHDFerrochelatase, mitochondrial4.99.1.10.447
1f8fNADBenzyl alcohol dehydrogenase/0.446
1g63FMNEpidermin decarboxylase4.1.10.446
1kiaSAMGlycine N-methyltransferase2.1.1.200.446
1oc1ASVIsopenicillin N synthase1.21.3.10.446
1xddAAYIntegrin alpha-L/0.446
2lfoGCHFatty acid-binding protein, liver/0.446
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.446
2vn1FK5Peptidylprolyl isomerase/0.446
2xviFADPutative flavin-containing monooxygenase/0.446
3c14FOKAdenylate cyclase type 2/0.446
3c14FOKAdenylate cyclase type 5/0.446
3frkTQPQdtB/0.446
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.446
3gsiTHGDimethylglycine oxidase1.5.3.100.446
3rbaCODPhosphopantetheine adenylyltransferase/0.446
3ukoNADAlcohol dehydrogenase class-3/0.446
3v0o4GWHisto-blood group ABO system transferase/0.446
4dbs0HVAldo-keto reductase family 1 member C3/0.446
4dyn0MRNucleoprotein/0.446
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4i1c1BEBeta-secretase 13.4.23.460.446
4jzyFADCryptochrome-1/0.446
5dp2NAPCurF/0.446
1dhrNADDihydropteridine reductase1.5.1.340.445
1kh3ANPArgininosuccinate synthase/0.445
1kl2FONSerine hydroxymethyltransferase/0.445
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.445
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.445
1rsgFADPolyamine oxidase FMS1/0.445
1u65CP0Acetylcholinesterase3.1.1.70.445
1vbiNADMalate/L-lactate dehydrogenase family protein/0.445
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.445
3b82NADExotoxin A2.4.2.360.445
3c1kT15Prothrombin3.4.21.50.445
3c3xNAPEugenol synthase 11.1.1.3180.445
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3ijdC2FMethylenetetrahydrofolate reductase/0.445
3qeoLLTDeoxycytidine kinase2.7.1.740.445
3wieDN4Glucose 1-dehydrogenase/0.445
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.445
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.445
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.445
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.445
5jj0SAMHistone-lysine N-methyltransferase EHMT2/0.445
1fwyUD1Bifunctional protein GlmU/0.444
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.444
1h61PDNPentaerythritol tetranitrate reductase/0.444
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.444
1x2hLPALipoate-protein ligase A6.3.1.200.444
1x8lOXRRetinol dehydratase/0.444
1z71L17Prothrombin3.4.21.50.444
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.444
2gesCOKPantothenate kinase2.7.1.330.444
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2pauD5M5'-deoxynucleotidase YfbR/0.444
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.444
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
3aezGDPPantothenate kinase2.7.1.330.444
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.444
3gwdNAPCyclohexanone monooxygenase/0.444
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.444
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.444
3p2oNADBifunctional protein FolD/0.444
3p62FMNPentaerythritol tetranitrate reductase/0.444
3vt8YI3Vitamin D3 receptor/0.444
3vyfVYFRenin3.4.23.150.444
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.444
4eb7PLPCysteine desulfurase IscS 2/0.444
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.444
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4lxk1YTBeta-secretase 13.4.23.460.444
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.443
1dr5NAPDihydrofolate reductase1.5.1.30.443
1fmlRTLRetinol dehydratase/0.443
1h73ANPHomoserine kinase2.7.1.390.443
1lkeDOGBilin-binding protein/0.443
1nm5NAPNAD(P) transhydrogenase subunit beta1.6.1.20.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2cv2GSUGlutamate--tRNA ligase6.1.1.170.443
2givACOHistone acetyltransferase KAT8/0.443
2vkvTDCTetracycline repressor protein class D/0.443
3br9DEYGenome polyprotein2.7.7.480.443
3dt2GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.443
3f6sFMNFlavodoxin/0.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3nsh957Beta-secretase 13.4.23.460.443
3oqfS51Renin3.4.23.150.443
3rsv3RSBeta-secretase 13.4.23.460.443
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.443
4a86H35Major pollen allergen Bet v 1-A/0.443
4cdmFO1Deoxyribodipyrimidine photolyase/0.443
4d04NAPPhenylacetone monooxygenase1.14.13.920.443
4dbzNDPPutative ketoacyl reductase1.3.10.443
4fhd0TTSpore photoproduct lyase/0.443
4i0i957Beta-secretase 13.4.23.460.443
4i6gFADCryptochrome-2/0.443
4ke11R6Beta-secretase 13.4.23.460.443
4phlPILPhosphodiesterase/0.443
4pvdNDPNADPH-dependent methylglyoxal reductase GRE2/0.443
4rheFMNFlavin prenyltransferase UbiX/0.443
4tyqAP5Adenylate kinase/0.443
1cnfFADNitrate reductase [NADH]1.7.1.10.442
1j49NADD-lactate dehydrogenase1.1.1.280.442
1pvgANPDNA topoisomerase 25.99.1.30.442
1re0AFBADP-ribosylation factor 1/0.442
1re0AFBARF guanine-nucleotide exchange factor 1/0.442
1s7gNADNAD-dependent protein deacylase 2/0.442
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.442
1wxjIPLTryptophan synthase alpha chain/0.442
2c20NADUDP-glucose 4-epimerase/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.442
2r8oT5XTransketolase 1/0.442
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.442
2zjuIM4Acetylcholine-binding protein/0.442
3akzGSUGlutamate--tRNA ligase 2/0.442
3c15FOKAdenylate cyclase type 2/0.442
3c15FOKAdenylate cyclase type 5/0.442
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.442
3gwfNAPCyclohexanone monooxygenase/0.442
3hdyGDUUDP-galactopyranose mutase/0.442
3rk1ATPN-type ATP pyrophosphatase superfamily/0.442
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.442
3to6LYS_CMCHistone acetyltransferase ESA1/0.442
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.442
4b68NAPL-ornithine N(5)-monooxygenase/0.442
4de10J6Beta-lactamase/0.442
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4h3j10WBeta-secretase 13.4.23.460.442
4iji99TGlutathione S-transferase-like protein YibF/0.442
4nbwNADShort-chain dehydrogenase/reductase SDR/0.442
1hfqMOTDihydrofolate reductase1.5.1.30.441
1obnASVIsopenicillin N synthase1.21.3.10.441
1s3uTQDDihydrofolate reductase1.5.1.30.441
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.441
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.441
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.441
1ygkRRCPyridoxal kinase2.7.1.350.441
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.441
2pg0FADAcyl-CoA dehydrogenase/0.441
2qs1UB1Glutamate receptor ionotropic, kainate 1/0.441
2rlcCHDCholoylglycine hydrolase3.5.1.240.441
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.441
3l5lFMNXenobiotic reductase/0.441
3p0fBAUUridine phosphorylase 22.4.2.30.441
3wqmB29Diterpene synthase3.1.7.80.441
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.441
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.441
4giu636Anthranilate phosphoribosyltransferase/0.441
4hmxFMNPyridoxamine 5'-phosphate oxidase/0.441
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.441
4loh1SYStimulator of interferon genes protein/0.441
4rn615UProthrombin3.4.21.50.441
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.441
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.441
5fm7ADPRuvB-like helicase/0.441
1beuIPLTryptophan synthase alpha chain/0.440
1cjtFOKAdenylate cyclase type 2/0.440
1cjtFOKAdenylate cyclase type 5/0.440
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.440
1fw0KAIGlutamate receptor 2/0.440
1icqOPD12-oxophytodienoate reductase 11.3.1.420.440
1ja0FADNADPH--cytochrome P450 reductase/0.440
1kp3ATPArgininosuccinate synthase6.3.4.50.440
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.440
1txtCAAHMG-CoA synthase/0.440
2a9y26AAdenosine kinase2.7.1.200.440
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.440
2fj1CTCTetracycline repressor protein class D/0.440
2gpjFADSiderophore-interacting protein/0.440
2he5NDPAldo-keto reductase family 1 member C211.1.10.440
2rqfJH3Hemolymph juvenile hormone binding protein/0.440
2vetUMPThymidylate synthase/0.440
2x6o2TCTetracycline repressor protein class D/0.440
2xuiTZ5Acetylcholinesterase3.1.1.70.440
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
2zfr46UProthrombin3.4.21.50.440
3b78NADExotoxin A2.4.2.360.440
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.440
3e8xNAPBH1520 protein/0.440
3f3sNADLambda-crystallin homolog/0.440
3g6zA7TRenin3.4.23.150.440
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.440
4ca63EFAngiotensin-converting enzyme3.2.10.440
4dh60KNBeta-secretase 13.4.23.460.440
4e32DWNMethyltransferase/0.440
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.440
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.440
4psbGA3Cytokinin-specific binding protein/0.440
5jy1NADPutative short-chain dehydrogenase/reductase/0.440
3pblETQD(3) dopamine receptor/0.440