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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3w2fFADNADH-cytochrome b5 reductase 31.6.2.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3w2fFADNADH-cytochrome b5 reductase 31.6.2.21.000
3w2eFADNADH-cytochrome b5 reductase 31.6.2.20.557
2wkyIBCGlutamate receptor ionotropic, kainate 1/0.515
1euyQSIGlutamine--tRNA ligase6.1.1.180.498
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.497
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.495
2qxxTTPdCTP deaminase3.5.4.130.493
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.493
5c1mCLRMu-type opioid receptor/0.493
3n0hTOPDihydrofolate reductase1.5.1.30.492
1d6w00RProthrombin3.4.21.50.487
1lkeDOGBilin-binding protein/0.487
1ypeUIPProthrombin3.4.21.50.487
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.484
3p9tTCLRepressor/0.484
4k9yK9YFocal adhesion kinase 12.7.10.20.484
1x8b824Wee1-like protein kinase2.7.10.20.481
2z2w770Wee1-like protein kinase2.7.10.20.481
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.481
1ypjUIBProthrombin3.4.21.50.480
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.480
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.480
1qvtPRLHTH-type transcriptional regulator QacR/0.479
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.479
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.478
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.478
4gn6TYLLactoperoxidase1.11.1.70.478
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.478
2in6839Wee1-like protein kinase2.7.10.20.477
3juqAKDPhenazine biosynthesis protein A/B/0.476
4n4v2GYTankyrase-12.4.2.300.476
1ae8AZLProthrombin3.4.21.50.475
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.475
2cn0F25Prothrombin3.4.21.50.474
4bfxZVXPantothenate kinase2.7.1.330.474
2j7cIDEBeta-glucosidase A3.2.1.210.473
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.473
4jq8KJ8Epidermal growth factor receptor2.7.10.10.471
1d3pBT3Prothrombin3.4.21.50.470
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.470
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.470
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.470
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.470
4jx1CAHCamphor 5-monooxygenase1.14.15.10.470
2q6hCXXNa(+):neurotransmitter symporter (Snf family)/0.469
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.469
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.469
4cbyKEEHistone deacetylase 43.5.1.980.469
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.469
4qa0SHHHistone deacetylase 83.5.1.980.469
4xulGTPUncharacterized protein mg662/0.469
1oc1ASVIsopenicillin N synthase1.21.3.10.468
1ypgUIRProthrombin3.4.21.50.468
2io6330Wee1-like protein kinase2.7.10.20.468
2x9vTMQPteridine reductase/0.468
3ubaHC4Lactoperoxidase1.11.1.70.468
4xoqF42Coenzyme F420:L-glutamate ligase/0.468
1xm1GAHProthrombin3.4.21.50.467
1xzqFONtRNA modification GTPase MnmE3.6.50.467
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.467
2v34CTN4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.467
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
1dr3HBIDihydrofolate reductase1.5.1.30.466
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.466
2acwUPGGlycosyltransferase/0.466
2zda32UProthrombin3.4.21.50.466
4bfuZVUPantothenate kinase2.7.1.330.466
4bfyZVYPantothenate kinase2.7.1.330.466
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.466
4lrrCF9Thymidylate synthase/0.466
1cqsEQUSteroid Delta-isomerase5.3.3.10.465
1ndzFR5Adenosine deaminase3.5.4.40.465
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.465
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.465
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.465
3stdMQ0Scytalone dehydratase4.2.1.940.465
3vo2FADFerredoxin--NADP reductase/0.465
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
1lnmDTXBilin-binding protein/0.464
1qrtATPGlutamine--tRNA ligase6.1.1.180.464
1qtiGNTAcetylcholinesterase3.1.1.70.464
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.464
3oafOAGDihydrofolate reductase1.5.1.30.464
3owsEQUSteroid Delta-isomerase5.3.3.10.464
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.464
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.463
3abaFLICytochrome P450/0.463
3c1kT15Prothrombin3.4.21.50.463
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.463
1wxyFRKAdenosine deaminase3.5.4.40.462
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.462
2xtbKRMAdenosine kinase, putative/0.462
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.462
4c717RD3-oxoacyl-ACP synthase/0.462
4hfnCIY2-alkenal reductase (NADP(+)-dependent)/0.462
4lb2DM5Serum albumin/0.462
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.461
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.461
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3af4GCPPantothenate kinase2.7.1.330.461
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.461
4c9wVGH7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.461
4la0198Serum albumin/0.461
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.461
1e3vDXCSteroid Delta-isomerase5.3.3.10.460
2f6rACOBifunctional coenzyme A synthase/0.460
3p5sAVUCD38 molecule/0.460
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.460
4qtnNNRNicotinamide riboside transporter PnuC/0.460
1drfFOLDihydrofolate reductase1.5.1.30.459
1mvsDTMDihydrofolate reductase1.5.1.30.459
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.459
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3ihgFADAklavinone 12-hydroxylase RdmE/0.459
3p99LNPLanosterol 14-alpha-demethylase/0.459
3s41S41Glucokinase2.7.1.20.459
3vjcZGASqualene synthase2.5.1.210.459
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.459
4fu0ADPD-alanine--D-alanine ligase/0.459
4q15HFGProline--tRNA ligase6.1.1.150.459
5d1bTSNHistone deacetylase 83.5.1.980.459
1b2lNDCAlcohol dehydrogenase1.1.1.10.458
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.458
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.458
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.458
3c35KAIGlutamate receptor ionotropic, kainate 1/0.458
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.458
3ojxFMNNADPH--cytochrome P450 reductase/0.458
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.458
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.458
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.458
4qa2SHHHistone deacetylase 83.5.1.980.458
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.457
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
1mvtDTMDihydrofolate reductase1.5.1.30.457
1pqc444Oxysterols receptor LXR-beta/0.457
1t4v14AProthrombin3.4.21.50.457
1yplRA8Prothrombin3.4.21.50.457
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
3pgiF41Endothiapepsin3.4.23.220.457
3rhjNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.457
3v94WYQPhosphodiesterase/0.457
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.457
4pnmNU1Tankyrase-22.4.2.300.457
1gjrFADFerredoxin--NADP reductase1.18.1.20.456
1m9m6NINitric oxide synthase, endothelial1.14.13.390.456
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.456
2j0sANPEukaryotic initiation factor 4A-III3.6.4.130.456
2zhf49UProthrombin3.4.21.50.456
2zsdCOAPantothenate kinase2.7.1.330.456
3lzzGDPUncharacterized protein/0.456
3pg3DG7Mitogen-activated protein kinase 14/0.456
4a16H34Acetylcholinesterase3.1.1.70.456
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.456
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.456
5epvACPBlue-light-activated histidine kinase2.7.13.30.456
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.455
2gvdFKPAdenylate cyclase type 2/0.455
2gvdFKPAdenylate cyclase type 5/0.455
2rc6FADFerredoxin--NADP reductase/0.455
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.455
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.455
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.455
4bfsZVSPantothenate kinase2.7.1.330.455
4dbw511Aldo-keto reductase family 1 member C3/0.455
4g1nNZTPyruvate kinase PKM2.7.1.400.455
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.455
1afeALZProthrombin3.4.21.50.454
1d4pBPPProthrombin3.4.21.50.454
1d9i00PProthrombin3.4.21.50.454
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.454
1oh0EQUSteroid Delta-isomerase5.3.3.10.454
1tllFADNitric oxide synthase, brain1.14.13.390.454
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
2jedLG8Protein kinase C theta type2.7.11.130.454
2mokFMNFlavodoxin 1/0.454
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.454
2zymACXPeriplasmic binding protein/0.454
3biu10UProthrombin3.4.21.50.454
3c34KAIGlutamate receptor ionotropic, kainate 1/0.454
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3h3t16HCollagen type IV alpha-3-binding protein/0.454
3v0p4GWHisto-blood group ABO system transferase/0.454
4fw05KJNitric oxide synthase, brain1.14.13.390.454
1gtrATPGlutamine--tRNA ligase6.1.1.180.453
2bjsACVIsopenicillin N synthase1.21.3.10.453
2jh6894Prothrombin3.4.21.50.453
2ob0ACON-alpha-acetyltransferase 50/0.453
2vrjNCWBeta-glucosidase A3.2.1.210.453
3owuEQUSteroid Delta-isomerase5.3.3.10.453
4i8vBHFCytochrome P450 1A11.14.14.10.453
1cjtFOKAdenylate cyclase type 2/0.452
1cjtFOKAdenylate cyclase type 5/0.452
1s3uTQDDihydrofolate reductase1.5.1.30.452
1votHUPAcetylcholinesterase3.1.1.70.452
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2hnzPC0Gag-Pol polyprotein2.7.7.490.452
2xlrFADPutative flavin-containing monooxygenase/0.452
2y60M8FIsopenicillin N synthase1.21.3.10.452
2zc922UProthrombin3.4.21.50.452
2zevB71Geranylgeranyl pyrophosphate synthase/0.452
3af2ACPPantothenate kinase2.7.1.330.452
3g11P9C3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.452
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3junAKDPhenazine biosynthesis protein A/B/0.452
3o8gO8GHTH-type transcriptional regulator EthR/0.452
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.452
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.452
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.452
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.452
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.451
1o5rFR9Adenosine deaminase3.5.4.40.451
2bn4FMNNADPH--cytochrome P450 reductase/0.451
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.451
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.451
2ipjFFAAldo-keto reductase family 1 member C2/0.451
2qeiCXXNa(+):neurotransmitter symporter (Snf family)/0.451
2rd2QSIGlutamine--tRNA ligase6.1.1.180.451
3c3dFO12-phospho-L-lactate transferase/0.451
3nmpPYVAbscisic acid receptor PYL2/0.451
3zkuHCVIsopenicillin N synthase1.21.3.10.451
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.451
4dhyS41Glucokinase2.7.1.20.451
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.451
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.451
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.451
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.451
1fwyUD1Bifunctional protein GlmU/0.450
1h35R01Squalene--hopene cyclase4.2.1.1290.450
1s3vTQDDihydrofolate reductase1.5.1.30.450
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.450
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.450
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.450
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.450
4cx4HW9Nitric oxide synthase, brain1.14.13.390.450
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.450
3pblETQD(3) dopamine receptor/0.450
1bk0ACVIsopenicillin N synthase1.21.3.10.449
1dlrMXADihydrofolate reductase1.5.1.30.449
1mueCDDProthrombin3.4.21.50.449
1w7kADPDihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.449
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2bkkADPAminoglycoside 3'-phosphotransferase2.7.1.950.449
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2d2gDZZPhosphotriesterase/0.449
2zi224UProthrombin3.4.21.50.449
3bi6396Wee1-like protein kinase2.7.10.20.449
3cr0809Wee1-like protein kinase2.7.10.20.449
3fpkFADFerredoxin-NADP reductase/0.449
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.449
3zc3FADFerredoxin--NADP reductase1.18.1.20.449
3zkyWT4Isopenicillin N synthase1.21.3.10.449
4a83DXCMajor pollen allergen Bet v 1-A/0.449
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.449
1nhkCMPNucleoside diphosphate kinase2.7.4.60.448
1o6rR19Squalene--hopene cyclase4.2.1.1290.448
1qxlFR8Adenosine deaminase3.5.4.40.448
1rszDIHPurine nucleoside phosphorylase2.4.2.10.448
2b82ADNClass B acid phosphatase3.1.3.20.448
2be2R22Gag-Pol polyprotein2.7.7.490.448
2jh0701Prothrombin3.4.21.50.448
2vdyHCYCorticosteroid-binding globulin/0.448
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
3l8sBFFMitogen-activated protein kinase 14/0.448
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4g95OAGDihydrofolate reductase1.5.1.30.448
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4rn615UProthrombin3.4.21.50.448
1db56INPhospholipase A2, membrane associated/0.447
1u1d181Uridine phosphorylase2.4.2.30.447
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.447
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.447
2y6fM9FIsopenicillin N synthase1.21.3.10.447
2zg050UProthrombin3.4.21.50.447
3a1l2CCCytochrome P450/0.447
3bk2U5PRibonuclease J/0.447
3fp0FP015-O-acetyltransferase/0.447
3gkiCLRNiemann-Pick C1 protein/0.447
3k1wBFXRenin3.4.23.150.447
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.447
3qbwADPAnhydro-N-acetylmuramic acid kinase/0.447
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.447
3thrC2FGlycine N-methyltransferase2.1.1.200.447
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.447
4bfvZVVPantothenate kinase2.7.1.330.447
4dc0NDPPutative ketoacyl reductase1.3.10.447
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.447
5iw4NADNADH pyrophosphatase/0.447
1iiuRTLRetinol-binding protein 4/0.446
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.446
2cdcNAPGlucose 1-dehydrogenase/0.446
2ea4F79Methionine aminopeptidase 2/0.446
2lbaCHOFatty acid binding protein 6/0.446
2oz57XYUncharacterized protein/0.446
3biz61EWee1-like protein kinase2.7.10.20.446
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.446
3gkjHC3Niemann-Pick C1 protein/0.446
3inrGDUUDP-galactopyranose mutase5.4.99.90.446
3lfeZ84Mitogen-activated protein kinase 14/0.446
3owyEQUSteroid Delta-isomerase5.3.3.10.446
3rhrNDPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.446
3vv8B02Beta-secretase 13.4.23.460.446
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.446
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.446
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
5bn4ANPV-type ATP synthase alpha chain/0.446
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
5dc5B3NHistone deacetylase 83.5.1.980.446
1dpmEBPParathion hydrolase3.1.8.10.445
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1krv147Galactoside O-acetyltransferase2.3.1.180.445
1m17AQ4Epidermal growth factor receptor2.7.10.10.445
1nm6L86Prothrombin3.4.21.50.445
1pd8CO4Dihydrofolate reductase1.5.1.30.445
1pq944BOxysterols receptor LXR-beta/0.445
1qrsATPGlutamine--tRNA ligase6.1.1.180.445
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
1ypkCCRProthrombin3.4.21.50.445
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.445
2ejzSAHDiphthine synthase/0.445
2r6jNDPEugenol synthase 11.1.1.3180.445
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
2xy93ESAngiotensin-converting enzyme3.2.10.445
2zevIPEGeranylgeranyl pyrophosphate synthase/0.445
2znk31UProthrombin3.4.21.50.445
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.445
3pd4A3GThreonine--tRNA ligase6.1.1.30.445
3s3vTOPDihydrofolate reductase1.5.1.30.445
3vf60H6Glucokinase2.7.1.20.445
4ax9N5NProthrombin3.4.21.50.445
4ea2RWZDehydrosqualene synthase/0.445
4kf1HT5Aryldialkylphosphatase3.1.8.10.445
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.445
4xp4COCSodium-dependent dopamine transporter/0.445
4zs4ATPMyosin heavy chain kinase A2.7.11.70.445
1f28F89Thymidylate synthase2.1.1.450.444
1gs3EQUSteroid Delta-isomerase5.3.3.10.444
1hfqMOTDihydrofolate reductase1.5.1.30.444
1lhvNOGSex hormone-binding globulin/0.444
1v7aFRCAdenosine deaminase3.5.4.40.444
1xf0ASDAldo-keto reductase family 1 member C3/0.444
2a4xBLMMitomycin-binding protein/0.444
2bdyUNBProthrombin3.4.21.50.444
2i8cADPD-alanine--D-alanine ligase/0.444
2o7pNAPRiboflavin biosynthesis protein RibD/0.444
2pbzATPUncharacterized protein/0.444
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.444
2y37A54Nitric oxide synthase, inducible1.14.13.390.444
2zfq45UProthrombin3.4.21.50.444
3bw4FMNPutative 2-nitropropane dioxygenase/0.444
3cqeP91Wee1-like protein kinase2.7.10.20.444
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.444
3njoPYVAbscisic acid receptor PYR1/0.444
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.444
3up3XCAaceDAF-12/0.444
4bb3KKAIsopenicillin N synthase1.21.3.10.444
4dbs0HVAldo-keto reductase family 1 member C3/0.444
4ddrMMVDihydrofolate reductase1.5.1.30.444
4hy6FJ1Heat shock protein HSP 90-alpha/0.444
4iwv1J9Glucokinase2.7.1.20.444
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.444
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.444
5dp2NAPCurF/0.444
4u140HKMuscarinic acetylcholine receptor M3/0.444
1ewyFADFerredoxin--NADP reductase1.18.1.20.443
1kuxCA3Serotonin N-acetyltransferase/0.443
1pkfEPDEpothilone C/D epoxidase1.140.443
1vzqSHYProthrombin3.4.21.50.443
2glrGTXGlutathione S-transferase P 12.5.1.180.443
2o4gTMPThree-prime repair exonuclease 13.1.11.20.443
2xxyKAIGlutamate receptor ionotropic, kainate 2/0.443
2zb8IMNProstaglandin reductase 21.3.1.480.443
3o7wSAMLeucine carboxyl methyltransferase 12.1.1.2330.443
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4dk70KSOxysterols receptor LXR-beta/0.443
4isuIKMGlutamate receptor 2/0.443
4kfbT27Gag-Pol polyprotein2.7.7.490.443
4knzCB3Thymidylate synthase/0.443
5cc9DDFDihydrofolate reductase1.5.1.30.443
1culFOKAdenylate cyclase type 2/0.442
1culFOKAdenylate cyclase type 5/0.442
1kmsLIHDihydrofolate reductase1.5.1.30.442
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
1tl7ONMAdenylate cyclase type 2/0.442
1tl7ONMAdenylate cyclase type 5/0.442
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3qp6HL6Transcriptional activator, LuxR/UhpA family of regulators/0.442
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
4e37NDPCatalase1.11.1.60.442
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
5je2SAHMethyl transferase/0.442
1o6qR17Squalene--hopene cyclase4.2.1.1290.441
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.441
1uhlMEIRetinoic acid receptor RXR-beta/0.441
2c42TPPPyruvate synthase/0.441
2cbqTH2Neocarzinostatin/0.441
2wo7ASVIsopenicillin N synthase1.21.3.10.441
3bhrTHGThymidylate synthase/0.441
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.441
3ed1GA3Gibberellin receptor GID1/0.441
3fwfCAMCamphor 5-monooxygenase1.14.15.10.441
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.441
3jq9AX1Pteridine reductase, putative/0.441
3njoP2MAbscisic acid receptor PYR1/0.441
3qm4PN0Cytochrome P450 2D6/0.441
3t403RGIndole-3-glycerol phosphate synthase4.1.1.480.441
3tm4SAMUncharacterized protein/0.441
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.441
4a86H35Major pollen allergen Bet v 1-A/0.441
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.441
4bftZVTPantothenate kinase2.7.1.330.441
4jhiEMUNodulin-13/0.441
4jx1CAMCamphor 5-monooxygenase1.14.15.10.441
5g53NECAdenosine receptor A2a/0.441
1g63FMNEpidermin decarboxylase4.1.10.440
1getNAPGlutathione reductase1.8.1.70.440
1mq0BRDCytidine deaminase3.5.4.50.440
1nzq162Prothrombin3.4.21.50.440
1v79FR7Adenosine deaminase3.5.4.40.440
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.440
1z6tADPApoptotic protease-activating factor 1/0.440
2a9z26AAdenosine kinase2.7.1.200.440
2aclL05Oxysterols receptor LXR-alpha/0.440
2bvs2CEProthrombin3.4.21.50.440
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.440
2gdeSN3Prothrombin3.4.21.50.440
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.440
2zgx29UProthrombin3.4.21.50.440
3c36KAIGlutamate receptor ionotropic, kainate 1/0.440
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3g72A6TRenin3.4.23.150.440
3issEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
3o9lLPNRenin3.4.23.150.440
4c43FADFerredoxin--NADP reductase1.18.1.20.440
4xczT3QQdtf/0.440
5fm7ADPRuvB-like helicase/0.440