Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 1.000 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 1.000 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.585 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.585 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.553 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.553 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.513 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.513 | |
| 3vr8 | RQX | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.502 | |
| 3vr8 | RQX | Cytochrome b-large subunit | / | 0.502 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.498 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.495 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.495 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.494 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.494 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.494 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.492 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.486 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 3ae4 | N1M | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.481 | |
| 3ae4 | N1M | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.481 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.481 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.480 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.480 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.479 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.479 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.479 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.478 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.478 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.477 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.477 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.477 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.476 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.476 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.474 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.474 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.474 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.474 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.473 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.473 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.473 | |
| 2xls | NAP | Putative flavin-containing monooxygenase | / | 0.473 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.473 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.472 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.472 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.472 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.472 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.472 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.472 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.471 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.471 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.471 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.470 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.470 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.469 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.468 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.468 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.468 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.468 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.468 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.468 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.468 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.467 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.466 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.466 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.466 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.465 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.465 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.464 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.464 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.464 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.464 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.464 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.464 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.463 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.463 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.463 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.463 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.462 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.462 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.462 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.462 | |
| 3sud | SUE | Polyprotein | / | 0.462 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.462 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.461 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.461 | |
| 2v0u | FMN | NPH1-1 | / | 0.461 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.461 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.461 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.461 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.461 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.460 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.460 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.460 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 1g6o | ADP | Cag alpha | / | 0.459 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.459 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.459 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.459 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.459 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.459 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.459 | |
| 4jic | FMN | GTN Reductase | / | 0.459 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.459 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.458 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.458 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.458 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.458 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.458 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.458 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.458 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1j0b | 5PA | Putative 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.457 | |
| 1sre | HAB | Streptavidin | / | 0.457 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.457 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.457 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.457 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.457 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.457 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.457 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.456 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.456 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.456 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.456 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.455 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.455 | |
| 2po3 | T4K | 4-dehydrase | / | 0.455 | |
| 2uyw | BTN | Avd protein | / | 0.455 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.455 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.455 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.455 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.454 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.454 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.454 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.454 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.454 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.454 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.454 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.454 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.454 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.453 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.453 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3kai | 4FI | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 5.2.1.8 | 0.453 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.453 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.453 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.453 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.453 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.453 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.452 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.452 | |
| 2izf | BTN | Streptavidin | / | 0.452 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.452 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4jld | ADP | Adenylate kinase | / | 0.452 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.451 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.451 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3e39 | FMN | Nitroreductase | / | 0.451 | |
| 3koq | FMN | Putative nitroreductase | / | 0.451 | |
| 4boe | CLR | Japanin | / | 0.451 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.451 | |
| 4irn | FAD | AnaB | / | 0.451 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.451 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.450 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.450 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.450 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.450 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.450 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.449 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.449 | |
| 3b9l | AZZ | Serum albumin | / | 0.449 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.449 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.449 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.449 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.449 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.449 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.448 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.448 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.448 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2uyy | NA7 | Putative oxidoreductase GLYR1 | 1 | 0.448 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.448 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.447 | |
| 2xvv | 9DN | Serum albumin | / | 0.447 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.447 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 4ap3 | NAP | Steroid monooxygenase | / | 0.447 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.447 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.447 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.447 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.447 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.447 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.446 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.446 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3dl0 | AP5 | Adenylate kinase | / | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.446 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.446 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.446 | |
| 4xw5 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.446 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.445 | |
| 2izh | BTN | Streptavidin | / | 0.445 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.445 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 4ozn | ATP | Ammonium transporter | / | 0.445 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.445 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.445 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1eu1 | MGD | Dimethyl sulfoxide/trimethylamine N-oxide reductase | / | 0.444 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2bxo | OPB | Serum albumin | / | 0.444 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.444 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.444 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.444 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.444 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.444 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.444 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.444 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.444 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2dqm | BES | Aminopeptidase N | 3.4.11.2 | 0.443 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.443 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.443 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2vig | COS | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.443 | |
| 3arv | SAU | Chitinase A | / | 0.443 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.442 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1nec | FMN | Oxygen-insensitive NAD(P)H nitroreductase | 1 | 0.442 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.442 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3a3g | DLZ | Lumazine protein | / | 0.442 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.442 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.442 | |
| 4hy0 | 1AQ | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.442 | |
| 5cpm | FNR | NADH:flavin oxidoreductase | / | 0.442 | |
| 1avd | BTN | Avidin | / | 0.441 | |
| 1e2n | RCA | Thymidine kinase | / | 0.441 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.441 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.441 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3eku | CY9 | Actin-5C | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.441 | |
| 4dja | FAD | (6-4) photolyase | / | 0.441 | |
| 4dve | BTN | Biotin transporter BioY | / | 0.441 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.441 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.441 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.441 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.441 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.440 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.440 | |
| 1t5b | FMN | FMN-dependent NADH-azoreductase | / | 0.440 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.440 | |
| 2cwf | NDP | Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase | / | 0.440 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3bkk | KAF | Angiotensin-converting enzyme | 3.2.1 | 0.440 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.440 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.440 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.440 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.440 | |
| 4ki0 | ANP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.440 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.440 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.440 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.440 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 |