Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 1.000 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.714 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.638 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.619 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.591 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.587 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.582 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.582 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.581 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.576 | |
| 2o2u | 738 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.563 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.559 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.536 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.535 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.524 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.521 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.521 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.516 | |
| 3vqu | O22 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.516 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.514 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.513 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.509 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.509 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.509 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.506 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.506 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.506 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.506 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.505 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.504 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.503 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.503 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.502 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.502 | |
| 4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.502 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.501 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.501 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.501 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.500 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.500 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.500 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.500 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.498 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.498 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.497 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.497 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.495 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.494 | |
| 2zdu | 446 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.494 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.493 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.493 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.493 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.493 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.492 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.492 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.492 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 3v3v | MYU | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.492 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.492 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.492 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.489 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.488 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.488 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.488 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.488 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.488 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.487 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.487 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.487 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.487 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.487 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.487 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.486 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.486 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.486 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.486 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.485 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.485 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.485 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.484 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.484 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.484 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.484 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.483 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.483 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.483 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.483 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.483 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.482 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.482 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.481 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.481 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.481 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.481 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.481 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.480 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.480 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.480 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.480 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.480 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.480 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.480 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.479 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.479 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.479 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.478 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.478 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.478 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.477 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.477 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.477 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.477 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.476 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.476 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.476 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.476 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.476 | |
| 4c4f | 7CE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.476 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.476 | |
| 5dmz | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.476 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.475 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.475 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.475 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.475 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.474 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.474 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.473 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.473 | |
| 4cta | ATP | CinA-like protein | / | 0.473 | |
| 4o0u | ADN | Aurora kinase A | 2.7.11.1 | 0.473 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.473 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.472 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.472 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.472 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.472 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.472 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 5l8l | ADP | Aurora kinase A | 2.7.11.1 | 0.472 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.471 | |
| 2yww | ATP | Aspartate carbamoyltransferase regulatory chain | / | 0.471 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.471 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.471 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.471 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.470 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.470 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.470 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.470 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.470 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.470 | |
| 1gqt | ACP | Ribokinase | / | 0.469 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.469 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.469 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.469 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.469 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 5a3c | NAD | SIR2 family protein | / | 0.469 | |
| 5ap5 | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.469 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.468 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.468 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.468 | |
| 3vth | APC | Carbamoyltransferase | / | 0.468 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.468 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 5a3b | APR | SIR2 family protein | / | 0.468 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.468 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.467 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.467 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.467 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.467 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.467 | |
| 3zuy | TCH | Transporter | / | 0.467 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.467 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.467 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.467 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.467 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.466 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.466 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.466 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.466 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.466 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.466 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.466 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.466 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.465 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.465 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.465 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.465 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.465 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.465 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.465 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.465 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.465 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.464 | |
| 2x2k | X2K | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.464 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.464 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.464 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.464 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.464 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.464 | |
| 4bi1 | ZO6 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.464 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.464 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.464 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.464 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.464 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.463 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.463 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.463 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.463 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.463 | |
| 3qqs | 17C | Anthranilate phosphoribosyltransferase | / | 0.463 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.463 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.463 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.463 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.462 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.462 | |
| 4bi0 | Z0W | Dual specificity protein kinase TTK | 2.7.12.1 | 0.462 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.462 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.461 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.461 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.461 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.461 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.461 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.461 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.461 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.461 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.461 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.461 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.461 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.461 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.460 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.460 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.460 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.459 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.459 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.459 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.459 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.459 | |
| 3umo | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.459 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.459 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.459 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.458 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.458 | |
| 3fc1 | 52P | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.458 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.458 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.458 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.458 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.457 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.457 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.457 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.457 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.457 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.457 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.457 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.456 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.456 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.456 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.456 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.456 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.456 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.456 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.456 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.456 | |
| 5doz | NDP | JamJ | / | 0.456 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.455 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.455 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.455 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.455 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.455 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.455 | |
| 4a0m | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.455 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 4l9k | EHF | Serum albumin | / | 0.455 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.455 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.454 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.454 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.454 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.454 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.454 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.454 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 4b0g | VEK | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.454 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.454 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.453 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3lu7 | IPX | Serum albumin | / | 0.453 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.453 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 4o1p | ANP | Ribonuclease L | / | 0.453 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.453 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.453 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.453 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.452 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.452 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.452 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.452 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.452 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.452 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.452 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1ie4 | T44 | Transthyretin | / | 0.451 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.451 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.451 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.451 | |
| 3rus | ADP | Chaperonin | / | 0.451 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4h4w | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.451 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.451 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.451 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.450 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.450 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2w1e | L0E | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.450 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3gob | HXX | DdmC | / | 0.450 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.450 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.450 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.450 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.450 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.450 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.450 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.449 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.449 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.449 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.449 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.449 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.449 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.449 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.449 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.449 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.449 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.448 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.448 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.448 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.448 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.448 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.448 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.448 | |
| 4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.448 | |
| 1bwf | ATF | Glycerol kinase | / | 0.447 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.447 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.447 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.447 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.447 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.447 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.447 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.447 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.447 | |
| 3q92 | XNB | Ketohexokinase | / | 0.447 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.447 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.447 | |
| 4c3r | ACP | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.447 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.447 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.447 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.447 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.446 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.446 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3eej | 53R | Uncharacterized protein | / | 0.446 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.446 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 3zxt | ACP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.446 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 5dnr | ATP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1ict | T44 | Transthyretin | / | 0.445 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.445 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.445 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.445 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 3rpr | 25Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.445 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.445 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.445 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.444 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.444 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.444 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.444 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.444 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.444 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.444 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.444 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 4be7 | ATP | Type I restriction enzyme EcoR124II R protein | 3.1.21.3 | 0.444 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.444 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.443 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1pkg | ADP | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.443 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.443 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2w1g | L0G | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.443 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.443 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.443 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.443 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.443 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.443 | |
| 3zux | TCH | Transporter | / | 0.443 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.443 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.443 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.442 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.442 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.442 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.442 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.442 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3c5u | P41 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.442 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.442 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.442 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4s34 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.442 | |
| 4xj3 | GTP | Cyclic GMP-AMP synthase | / | 0.442 | |
| 5ijz | NAP | NADP-specific glutamate dehydrogenase | 1.4.1.4 | 0.442 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.441 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.441 | |
| 1zgd | NAP | Chalcone reductase | / | 0.441 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.441 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2x2m | X2M | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.441 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.441 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.441 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.441 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.441 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.441 | |
| 4jd3 | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.441 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.441 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.441 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 5c41 | ACP | Ribokinase | / | 0.441 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.441 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1okk | GCP | Signal recognition particle protein | / | 0.440 | |
| 1okk | GCP | Signal recognition particle receptor FtsY | / | 0.440 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.440 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.440 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.440 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.440 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.440 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.440 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.440 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4hys | 1BJ | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.440 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.440 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 |