sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3f8d | FAD | NADH oxidase/thioredoxin reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 1.386 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.980 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.975 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.958 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.952 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.949 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.939 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.932 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.931 | |
| 3fbs | FAD | Oxidoreductase | / | 0.928 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.925 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.920 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.909 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.901 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.897 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.888 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.886 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.885 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.880 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.871 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.870 | |
| 4nte | FAD | DepH | / | 0.866 | |
| 2bac | FAD | Putative aminooxidase | / | 0.863 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.860 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.852 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.849 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.848 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.845 | |
| 4nev | FAD | Trypanothione reductase | / | 0.845 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.840 | |
| 4jn9 | FAD | DepH | / | 0.840 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.839 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.839 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.837 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.836 | |
| 2qa1 | FAD | PgaE | / | 0.834 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.834 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.833 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.831 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.831 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.831 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.828 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.827 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.826 | |
| 2bab | FAD | Putative aminooxidase | / | 0.822 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.821 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.821 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.820 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.819 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.819 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.818 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.817 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.817 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.814 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.814 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.813 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.812 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.809 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.809 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.809 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.808 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.808 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.808 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.807 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.807 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.806 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.805 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.804 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.804 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.802 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.801 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.799 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.799 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.798 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.798 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.797 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.797 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.796 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.796 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.792 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.792 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.792 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.791 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.791 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.791 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.790 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.790 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.790 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.790 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.788 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.787 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.786 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.786 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.785 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.785 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.783 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.782 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.782 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.781 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.781 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.781 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.780 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.780 | |
| 3rha | FDA | Putrescine oxidase | / | 0.780 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.779 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.778 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.777 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.777 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.774 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.773 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.773 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.772 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.771 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.769 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.769 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.769 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.769 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.767 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.767 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.767 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.767 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.765 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.765 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.763 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.762 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.761 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.760 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.760 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.760 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.760 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.760 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.759 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.759 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.759 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.758 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.758 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.758 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.757 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.757 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.757 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.757 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.756 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.755 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.755 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.755 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.754 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.754 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.754 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.753 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.753 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.753 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.753 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.752 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.752 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.752 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.752 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.751 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.751 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.751 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.751 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.750 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.750 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.749 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.749 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.749 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.748 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.748 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.748 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.748 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.747 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.747 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.747 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.747 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.747 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.746 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.746 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.745 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.744 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.744 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.744 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.744 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.744 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.744 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.743 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.743 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.743 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.742 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.742 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.742 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.741 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.740 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.740 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.740 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.740 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.739 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.739 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.739 | |
| 4h4s | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.739 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.736 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.736 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.735 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.735 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.734 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.734 | |
| 3ukk | FDA | UDP-galactopyranose mutase | / | 0.734 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.732 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.732 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.732 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.731 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.731 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.731 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.731 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.730 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.730 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.729 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.729 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.728 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.728 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.728 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.727 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.727 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.727 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.727 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.726 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.726 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.725 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.724 | |
| 2wow | FAD | Trypanothione reductase | / | 0.724 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.724 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.724 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.724 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.724 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.724 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.723 | |
| 2cul | FAD | GidA-related protein | / | 0.723 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.723 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.722 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.722 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.722 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.722 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.722 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.721 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.721 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.721 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.720 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.719 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.719 | |
| 4k5r | FAD | Oxygenase | / | 0.719 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.718 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.718 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.718 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.718 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.717 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.717 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.717 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.717 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.717 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.716 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.716 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.715 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.715 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.715 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.715 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.715 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.714 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.714 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.713 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.713 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.713 | |
| 4x4j | FAD | Putative oxygenase | / | 0.713 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.712 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.712 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.712 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.712 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.711 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.711 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.711 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.710 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.710 | |
| 3uka | FAD | UDP-galactopyranose mutase | / | 0.710 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.710 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.709 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.709 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.709 | |
| 4h4y | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.709 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.708 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.707 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.707 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.707 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.707 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.706 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.706 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.706 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.706 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.705 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.705 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.704 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.704 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.704 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.703 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.703 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.703 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.702 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.702 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.701 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.701 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.701 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.700 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.700 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.699 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.699 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.699 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.699 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.699 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.699 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.698 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.698 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.698 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.698 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.697 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.697 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.697 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.697 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.697 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.696 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.696 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.696 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.696 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.694 | |
| 4ysh | FAD | Glycine oxidase | / | 0.694 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.693 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.693 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.693 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.692 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.692 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.692 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.692 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.692 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.691 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.691 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.691 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.690 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.690 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.690 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.690 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.689 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.689 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.689 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.689 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.689 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.688 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.688 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.688 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.687 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.687 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.686 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.686 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.686 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.686 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.685 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.685 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.684 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.684 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.684 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.684 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.683 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.683 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.683 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.682 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.682 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.682 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.682 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.681 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.681 | |
| 3kkj | FAD | Renalase | / | 0.681 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.681 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.680 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.680 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.680 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.680 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.680 | |
| 4icy | FAD | PgaE | / | 0.680 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.679 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.679 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.678 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.678 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.677 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.677 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.677 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.677 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.677 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.677 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.676 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.676 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.676 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.676 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.676 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.676 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.676 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.675 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.674 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.674 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.674 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.673 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.673 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.673 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.672 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.672 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.672 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.672 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.671 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.671 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.670 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.670 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.670 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.670 | |
| 2v7g | NAD | Urocanate hydratase | 4.2.1.49 | 0.669 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.669 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.669 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.668 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.668 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.668 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.668 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.667 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.667 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.666 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.666 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.666 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.666 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.665 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.665 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.665 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.665 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.664 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.664 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.664 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.664 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.663 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.663 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.662 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.662 | |
| 4hia | FMN | LOV protein | / | 0.661 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.660 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.660 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.660 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.659 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.658 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.658 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.658 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.657 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.657 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.656 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.656 | |
| 4tm3 | FAD | KtzI | / | 0.656 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.655 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.655 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.655 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.655 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.654 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.654 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.654 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.654 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.654 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.654 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.653 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.653 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.652 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.652 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.652 | |
| 1n9n | FMN | Putative blue light receptor | / | 0.651 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.651 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.651 | |
| 5efw | FMN | NPH1-1 | / | 0.651 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.650 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.650 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.650 |