sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 1.000 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.518 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.506 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.503 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.494 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.494 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.494 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.487 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.485 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.483 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.482 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.481 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.480 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.479 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1ppj | ANY | Cytochrome b | / | 0.477 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.477 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.476 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.475 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.475 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.475 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.475 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.473 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.472 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.472 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.472 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.472 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.471 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.470 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 3bxr | DRR | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.470 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.470 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.470 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.469 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.468 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.468 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.468 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.468 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.468 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.468 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.468 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.468 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.467 | |
| 1gqt | ACP | Ribokinase | / | 0.466 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.466 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.466 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.466 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.466 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.466 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.466 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.465 | |
| 3nxe | 2NC | Protease | / | 0.465 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.465 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.465 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.465 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.464 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.464 | |
| 2p3b | 3TL | V-1 protease | / | 0.464 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.464 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.463 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.463 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.463 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.463 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.463 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.463 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.462 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.462 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.461 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.461 | |
| 3gob | HXX | DdmC | / | 0.461 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.461 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.461 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.461 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.461 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.460 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.460 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.460 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.460 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3ieu | GDP | GTPase Era | / | 0.459 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.459 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.459 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.459 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.459 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.459 | |
| 1daz | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.458 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.458 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.458 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.458 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.458 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.458 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.458 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.458 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.457 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.457 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.457 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.457 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.457 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.457 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.457 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.457 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.457 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.457 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.457 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.456 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.456 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.456 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.456 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.456 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.456 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.456 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.456 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.456 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.455 | |
| 2bxm | IMN | Serum albumin | / | 0.455 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.455 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.455 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.455 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.455 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.455 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.454 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.454 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.454 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.454 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.454 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.454 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.453 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.453 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.453 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.453 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4irn | FAD | AnaB | / | 0.453 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.453 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.453 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.452 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.452 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.452 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.452 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.452 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.452 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.452 | |
| 4l4x | NDP | AmphI | / | 0.452 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.452 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.451 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.451 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.451 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.451 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.451 | |
| 2ejz | SAH | Diphthine synthase | / | 0.451 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.451 | |
| 2giq | NN2 | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.451 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.451 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.451 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 3wec | AUI | Cytochrome P450 | / | 0.451 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.451 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.450 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.450 | |
| 2xvv | 9DN | Serum albumin | / | 0.450 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.450 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.450 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.450 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.450 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.449 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2cen | 4AH | Protease | / | 0.449 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.449 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.449 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.449 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.449 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.449 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.449 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.449 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.449 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.449 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.448 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.448 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.448 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.448 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.448 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.448 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.448 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4a4q | UX9 | Pol protein | / | 0.448 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 2p3d | 3TL | Protease | / | 0.447 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.447 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.447 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.447 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.447 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.447 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.447 | |
| 4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.447 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.447 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.446 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.446 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.446 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.446 | |
| 3e8x | NAP | BH1520 protein | / | 0.446 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.446 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.446 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.446 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.446 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.446 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.446 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.445 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.445 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.445 | |
| 2ele | SAH | Diphthine synthase | / | 0.445 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2hux | SAH | Diphthine synthase | / | 0.445 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.445 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3lxk | MI1 | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.445 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 4kb9 | G79 | Protease | / | 0.445 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.445 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1hvi | A77 | Protease | / | 0.444 | |
| 1izh | Q50 | Protease | / | 0.444 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.444 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.444 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.444 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2pch | SAH | Diphthine synthase | / | 0.444 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2q29 | ACO | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.444 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.444 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.444 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.444 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4jkt | 04A | Glutaminase kidney isoform, mitochondrial | 3.5.1.2 | 0.444 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.444 | |
| 4yaf | FAD | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.444 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.444 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.444 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1efa | NPF | Lactose operon repressor | / | 0.443 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.443 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.443 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.443 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.443 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3ekw | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.443 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.443 | |
| 3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3so9 | 017 | Pol protein | / | 0.443 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.443 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.443 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4cdm | FAD | Deoxyribodipyrimidine photolyase | / | 0.443 | |
| 4dqw | ATP | Inosine-5'-monophosphate dehydrogenase | / | 0.443 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.443 | |
| 1a8k | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.442 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.442 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.442 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.442 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.442 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.442 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.442 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.442 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.442 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.442 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.442 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.442 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.441 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.441 | |
| 2p5c | SAH | Diphthine synthase | / | 0.441 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.441 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.441 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2z6r | SAH | Diphthine synthase | / | 0.441 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.441 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.441 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3ndt | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.441 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.441 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.441 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1mtr | PI6 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.440 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2ejj | SAH | Diphthine synthase | / | 0.440 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 2nnp | ROC | Protease | / | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3bnk | FMN | Flavoredoxin | / | 0.440 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3o96 | IQO | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.440 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.440 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.440 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4fux | E75 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.440 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.440 |