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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1xz85GPBifunctional protein PyrR2.4.2.9

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1xz85GPBifunctional protein PyrR2.4.2.91.000
2oapANPType II secretion system protein (GspE-2)/0.527
3p62FMNPentaerythritol tetranitrate reductase/0.506
2abbFMNPentaerythritol tetranitrate reductase/0.497
2q4bNAPUncharacterized protein At5g02240/0.496
2iyfERYOleandomycin glycosyltransferase2.4.10.495
1me6IVSPlasmepsin-23.4.23.390.494
3p74FMNPentaerythritol tetranitrate reductase/0.491
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.490
1udbUFGUDP-glucose 4-epimerase5.1.3.20.486
3f03FMNPentaerythritol tetranitrate reductase/0.486
5fltVJJCarbonic anhydrase 24.2.1.10.486
1h51FMNPentaerythritol tetranitrate reductase/0.485
2d29FADAcyl-CoA dehydrogenase/0.485
4m83ERYOleandomycin glycosyltransferase2.4.10.485
4bfuZVUPantothenate kinase2.7.1.330.484
1nzfUPGDNA beta-glucosyltransferase/0.483
4a6nFADTetX family tetracycline inactivation enzyme/0.482
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.480
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.480
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.480
3s1dZIRCytokinin dehydrogenase 11.5.99.120.480
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.478
3tr05GPGuanylate kinase/0.478
1xe55FEPlasmepsin-23.4.23.390.477
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.477
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.477
1h63FMNPentaerythritol tetranitrate reductase/0.476
1h74ADPHomoserine kinase2.7.1.390.476
2futH1SHeparin and heparin-sulfate lyase/0.476
3h3qH13Collagen type IV alpha-3-binding protein/0.476
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.476
4j0t6T9Beta-secretase 13.4.23.460.475
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.473
4f9gC2EStimulator of interferon genes protein/0.472
4y9uNAPNADPH--cytochrome P450 reductase/0.472
1o9bNAIQuinate/shikimate dehydrogenase/0.471
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.471
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.471
3v2uATPProtein GAL3/0.471
4dfg0JVGag-Pol polyprotein3.4.23.160.471
4kgkGTPUncharacterized protein/0.471
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.470
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.470
4a862ANMajor pollen allergen Bet v 1-A/0.470
1kp2ATPArgininosuccinate synthase6.3.4.50.469
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.469
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.469
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.468
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.468
2qw034Z4-chlorobenzoyl CoA ligase/0.468
2rqfJH3Hemolymph juvenile hormone binding protein/0.468
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3hf3FMNChromate reductase/0.468
3nsh957Beta-secretase 13.4.23.460.468
4i0i957Beta-secretase 13.4.23.460.468
4uocNCNCinA-like protein/0.468
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.467
1pq944BOxysterols receptor LXR-beta/0.467
2fznFADBifunctional protein PutA1.5.5.20.467
1xe65FPPlasmepsin-23.4.23.390.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
4a8v2ANMajor pollen allergen Bet v 1-J/0.466
3qt62P0Mevalonate diphosphate decarboxylase/0.465
4du82P0Mevalonate diphosphate decarboxylase/0.465
5a3cNADSIR2 family protein/0.465
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.464
1psa0ZLPepsin A3.4.23.10.464
1xvaSAMGlycine N-methyltransferase2.1.1.200.464
3uylTYDProbable NDP-rhamnosyltransferase/0.464
2bt4CA23-dehydroquinate dehydratase4.2.1.100.463
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.463
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.463
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
3ensENSCoagulation factor X3.4.21.60.463
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.463
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.463
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.463
1h50FMNPentaerythritol tetranitrate reductase/0.462
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.462
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.462
2dfvNADL-threonine 3-dehydrogenase/0.462
2il2LIXRenin3.4.23.150.462
4xj43ATCyclic GMP-AMP synthase/0.462
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.461
2y3sTIRTamL/0.461
3ctyFADProbable thioredoxin reductase/0.461
3lpiZ74Beta-secretase 13.4.23.460.461
3vswR31Renin3.4.23.150.461
4dpwAGSMevalonate diphosphate decarboxylase/0.461
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.460
1k7l544Peroxisome proliferator-activated receptor alpha/0.460
2c20NADUDP-glucose 4-epimerase/0.460
2fj1CTCTetracycline repressor protein class D/0.460
3triNAPPyrroline-5-carboxylate reductase/0.460
4ipw1G7Mycocyclosin synthase1.14.21.90.460
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.460
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.460
1nzdUPGDNA beta-glucosyltransferase/0.459
1r2jFADFkbI/0.459
1zgv501Prothrombin3.4.21.50.459
2g1s4IGRenin3.4.23.150.459
2hfuMEVMevalonate kinase/0.459
4blrUTPNTPase P4/0.459
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.459
4yal2AMNADPH--cytochrome P450 reductase/0.459
1g6kNADGlucose 1-dehydrogenase1.1.1.470.458
1kfbIGPTryptophan synthase alpha chain/0.458
1vyrFMNPentaerythritol tetranitrate reductase/0.458
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.458
2dftADPShikimate kinase2.7.1.710.458
2hejNDPAldo-keto reductase family 1 member C211.1.10.458
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.458
3br3ETHTH-type transcriptional regulator QacR/0.458
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.458
3kigDA4Carbonic anhydrase 24.2.1.10.458
3pcrGTPADP-ribosylation factor 6/0.458
4opgFDAConserved Archaeal protein/0.458
4q71FADBifunctional protein PutA/0.458
1bil0IURenin3.4.23.150.457
1npdNADQuinate/shikimate dehydrogenase/0.457
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.457
1zrzBI1Protein kinase C iota type2.7.11.130.457
2bpoNAPNADPH--cytochrome P450 reductase/0.457
2cy0NAPShikimate dehydrogenase (NADP(+))/0.457
2rcyNAPPyrroline-5-carboxylate reductase/0.457
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.457
3lqfNADGalactitol dehydrogenase/0.457
3sf6FDAGlutaryl-CoA dehydrogenase/0.457
3wv7ADPHmd co-occurring protein HcgE/0.457
4d89BXDBeta-secretase 13.4.23.460.457
3co93MSGenome polyprotein2.7.7.480.456
4k28NADShikimate dehydrogenase family protein/0.456
1c7oPPGHemolysin/0.455
1i5eU5PUracil phosphoribosyltransferase/0.455
1tehNADAlcohol dehydrogenase class-31.1.1.10.455
1u71MXADihydrofolate reductase1.5.1.30.455
1w6hTITPlasmepsin-23.4.23.390.455
1z4uPH9Polyprotein/0.455
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.455
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.455
3gegNADShort-chain dehydrogenase/reductase SDR/0.455
3otwCOAPhosphopantetheine adenylyltransferase/0.455
3rk1ATPN-type ATP pyrophosphatase superfamily/0.455
3tjzGNPADP-ribosylation factor 1/0.455
3vilSA0Beta-glucosidase/0.455
4b63NAPL-ornithine N(5)-monooxygenase/0.455
4b68NAPL-ornithine N(5)-monooxygenase/0.455
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4uugPXGBranched-chain amino acid aminotransferase, putative/0.455
1cbqRE9Cellular retinoic acid-binding protein 2/0.454
1rd7FOLDihydrofolate reductase1.5.1.30.454
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.454
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.454
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.454
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.454
3nxxNDPDihydrofolate reductase1.5.1.30.454
3w6hAZMCarbonic anhydrase 14.2.1.10.454
4a802ANMajor pollen allergen Bet v 1-A/0.454
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.454
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.454
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.454
4xr9NADCalS8/0.454
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.453
2rc4ACOHistone acetyltransferase KAT6A/0.453
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.453
4dpy2P0Mevalonate diphosphate decarboxylase/0.453
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.453
4x5iFOLDihydrofolate reductase1.5.1.30.453
3v2yML5Sphingosine 1-phosphate receptor 1/0.453
1ay0TPPTransketolase 12.2.1.10.452
1dliUDXUDP-glucose 6-dehydrogenase/0.452
1nb6UTPGenome polyprotein2.7.7.480.452
1y9dTPPPyruvate oxidase1.2.3.30.452
2abaSTRPentaerythritol tetranitrate reductase/0.452
2b53D23Cyclin-dependent kinase 22.7.11.220.452
2dxiATPGlutamate--tRNA ligase6.1.1.170.452
2qimZEAClass 10 plant pathogenesis-related protein/0.452
2rlcCHDCholoylglycine hydrolase3.5.1.240.452
2wb2FADRE11660p/0.452
2xupTZ5Acetylcholinesterase3.1.1.70.452
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.452
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.452
3lqsPSZD-alanine aminotransferase2.6.1.210.452
4rvnCOAPhenylacetate-coenzyme A ligase/0.452
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.452
1dyiFOLDihydrofolate reductase1.5.1.30.451
1u1f183Uridine phosphorylase2.4.2.30.451
2c12FADNitroalkane oxidase1.7.3.10.451
2ed3SAHDiphthine synthase/0.451
2i4qUA4Renin3.4.23.150.451
2iqgF2IBeta-secretase 13.4.23.460.451
2xfiXFIBeta-secretase 13.4.23.460.451
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3gfbNADL-threonine 3-dehydrogenase/0.451
3ufl508Beta-secretase 13.4.23.460.451
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.450
1ra3MTXDihydrofolate reductase1.5.1.30.450
1udaUFGUDP-glucose 4-epimerase5.1.3.20.450
1xddAAYIntegrin alpha-L/0.450
1xq6NAPUncharacterized protein At5g02240/0.450
2anb5GPGuanylate kinase2.7.4.80.450
2vyqFADFerredoxin--NADP reductase1.18.1.20.450
2w3bNDPDihydrofolate reductase1.5.1.30.450
2wu4HBPAcetylcholinesterase3.1.1.70.450
3ed1GA3Gibberellin receptor GID1/0.450
4wriOKAOkadaic acid binding protein 2-alpha/0.450
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.449
1mjbACOHistone acetyltransferase ESA1/0.449
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.449
1szgFNSCytochrome b2, mitochondrial1.1.2.30.449
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.449
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.449
2cekN8TAcetylcholinesterase3.1.1.70.449
2ikuLIYRenin3.4.23.150.449
2po7CHDFerrochelatase, mitochondrial4.99.1.10.449
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.449
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.449
3iocA5DPantothenate synthetase6.3.2.10.449
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.449
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.449
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.449
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.449
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.449
1g1aNADdTDP-glucose 4,6-dehydratase/0.448
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.448
1vf2GTXGlutathione S-transferase 32.5.1.180.448
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
2fy4COACholine O-acetyltransferase2.3.1.60.448
2g1n1IGRenin3.4.23.150.448
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.448
3drcMTXDihydrofolate reductase1.5.1.30.448
3fr5I4AFatty acid-binding protein, adipocyte/0.448
3lpkZ76Beta-secretase 13.4.23.460.448
3ou2SAHSAM-dependent methyltransferase/0.448
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.448
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4hyvPEPPyruvate kinase 12.7.1.400.448
4ycpFMNtRNA-dihydrouridine(16) synthase/0.448
5a3bAPRSIR2 family protein/0.448
1cnfFADNitrate reductase [NADH]1.7.1.10.447
1icsFMN12-oxophytodienoate reductase 11.3.1.420.447
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1rdwLARActin, alpha skeletal muscle/0.447
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.447
2dc1NADProbable L-aspartate dehydrogenase/0.447
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.447
3aezGDPPantothenate kinase2.7.1.330.447
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3h5uH5UGenome polyprotein2.7.7.480.447
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.447
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.447
3qviK95HAP protein/0.447
3t4eNADQuinate/shikimate dehydrogenase/0.447
3u9eCOALmo1369 protein/0.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.447
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.447
4f5yC2EStimulator of interferon genes protein/0.447
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.447
4i1nFOLDihydrofolate reductase1.5.1.30.447
4y9rNAPNADPH--cytochrome P450 reductase/0.447
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.446
1f20FADNitric oxide synthase, brain1.14.13.390.446
1ib6NADMalate dehydrogenase/0.446
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.446
1pd9CO4Dihydrofolate reductase1.5.1.30.446
1tllFMNNitric oxide synthase, brain1.14.13.390.446
1u1cBAUUridine phosphorylase2.4.2.30.446
2wf1ZY1Beta-secretase 13.4.23.460.446
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.446
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3fpaDTBATP-dependent dethiobiotin synthetase BioD/0.446
3fr4F8AFatty acid-binding protein, adipocyte/0.446
3h3r14HCollagen type IV alpha-3-binding protein/0.446
3k8q22APurine nucleoside phosphorylase2.4.2.10.446
3p84FMNPentaerythritol tetranitrate reductase/0.446
3phiNDPShikimate dehydrogenase (NADP(+))/0.446
3w8rACPUridine kinase/0.446
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4dpi0N1Beta-secretase 13.4.23.460.446
4eb5PLPCysteine desulfurase IscS 2/0.446
4w5kPLPAspartate aminotransferase, mitochondrial/0.446
5kwvANPPantothenate synthetase/0.446
1a5bIGPTryptophan synthase alpha chain/0.445
1bim0QBRenin3.4.23.150.445
1hb3SCVIsopenicillin N synthase1.21.3.10.445
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.445
1rneC60Renin3.4.23.150.445
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.445
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.445
2briANPUridylate kinase2.7.4.220.445
2f3rG5PGuanylate kinase2.7.4.80.445
2ou2ACOHistone acetyltransferase KAT5/0.445
2qbuSAHPrecorrin-2 methyltransferase/0.445
2uuk897Prothrombin3.4.21.50.445
3d91REMRenin3.4.23.150.445
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.445
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
3vsxR32Renin3.4.23.150.445
3wwmADP[LysW]-aminoadipate kinase/0.445
4a84DXCMajor pollen allergen Bet v 1-A/0.445
4bfzZVZPantothenate kinase2.7.1.330.445
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
4zwmPLPOrnithine aminotransferase, mitochondrial, putative/0.445
5hi6MTXDihydrofolate reductase/0.445
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.444
1h73ANPHomoserine kinase2.7.1.390.444
1nvtNAPShikimate dehydrogenase (NADP(+))/0.444
1q1wFADPutidaredoxin reductase1.18.1.50.444
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.444
1qcwFNSCytochrome b2, mitochondrial1.1.2.30.444
1tqf32PBeta-secretase 13.4.23.460.444
2f3mGTDGlutathione S-transferase Mu 12.5.1.180.444
2g8yNADHydroxycarboxylate dehydrogenase B/0.444
2hk9NAPShikimate dehydrogenase (NADP(+))/0.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
3ggj25HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.444
3r9uFADThioredoxin reductase/0.444
4fdaNAP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.444
4fhd0TTSpore photoproduct lyase/0.444
5dp2NAPCurF/0.444
1bk0ACVIsopenicillin N synthase1.21.3.10.443
1mj9COAHistone acetyltransferase ESA1/0.443
1n7hNDPGDP-mannose 4,6 dehydratase 24.2.1.470.443
1njjORXOrnithine decarboxylase/0.443
1pvgANPDNA topoisomerase 25.99.1.30.443
1qoqIGPTryptophan synthase alpha chain/0.443
1vikBAYGag-Pol polyprotein/0.443
1w5sADPORC1-type DNA replication protein 2/0.443
2dhfDZFDihydrofolate reductase1.5.1.30.443
2ea2F77Methionine aminopeptidase 2/0.443
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.443
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.443
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.443
2xlrFADPutative flavin-containing monooxygenase/0.443
3a0tADPSensor histidine kinase/0.443
3imeBZ2Pantothenate synthetase6.3.2.10.443
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.443
3kjm245Cytokinin dehydrogenase 11.5.99.120.443
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3pi53P5Beta-secretase 13.4.23.460.443
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.443
3upi0C2Genome polyprotein2.7.7.480.443
4b4vL34Bifunctional protein FolD/0.443
4j0y1H6Beta-secretase 13.4.23.460.443
4ke11R6Beta-secretase 13.4.23.460.443
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.443
5cyoGDPSeptin-9/0.443
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.442
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
2draATPCCA-adding enzyme2.7.7.720.442
2xviFADPutative flavin-containing monooxygenase/0.442
3atzFMNProstaglandin F2a synthase/0.442
3bsa1PDGenome polyprotein2.7.7.480.442
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.442
3h3t16HCollagen type IV alpha-3-binding protein/0.442
3junAKDPhenazine biosynthesis protein A/B/0.442
3veu0GOBeta-secretase 13.4.23.460.442
4btu6XSCoagulation factor X3.4.21.60.442
4e32DWNMethyltransferase/0.442
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
4psbGA3Cytokinin-specific binding protein/0.442
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.442
4yqfGDPSeptin-9/0.442
1f20NAPNitric oxide synthase, brain1.14.13.390.441
1f8fNADBenzyl alcohol dehydrogenase/0.441
1kkq471Peroxisome proliferator-activated receptor alpha/0.441
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1n2jPAFPantothenate synthetase6.3.2.10.441
1rfuADPPyridoxal kinase2.7.1.350.441
1t2cNAIL-lactate dehydrogenase1.1.1.270.441
1vi2NADQuinate/shikimate dehydrogenase/0.441
1xzqFONtRNA modification GTPase MnmE3.6.50.441
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.441
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.441
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2dvlFADAcyl-CoA dehydrogenase/0.441
2ft9CHDFatty acid-binding protein 2, liver/0.441
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.441
2gjnFMNNitronate monooxygenase1.13.12.160.441
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.441
2ntrL00Beta-secretase 13.4.23.460.441
2rg6287Mitogen-activated protein kinase 14/0.441
2zhe13UProthrombin3.4.21.50.441
3af1GDPPantothenate kinase2.7.1.330.441
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.441
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3i0pNADMalate dehydrogenase, putative/0.441
3tozNADShikimate dehydrogenase (NADP(+))/0.441
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.441
4rphGDUUDP-galactopyranose mutase5.4.99.90.441
4u0mATPCyclic GMP-AMP synthase/0.441
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.441
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.441
1drhNAPDihydrofolate reductase1.5.1.30.440
1mxfMTXPutative pteridine reductase 2/0.440
1ra8FOLDihydrofolate reductase1.5.1.30.440
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.440
2q14ADPPhosphohydrolase/0.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.440
3akzGSUGlutamate--tRNA ligase 2/0.440
3b1dPLSBetaC-S lyase/0.440
3f63GTXGlutathione transferase GST1-4/0.440
3fun798Leukotriene A-4 hydrolase3.3.2.60.440
3ixj586Beta-secretase 13.4.23.460.440
3p82FMNPentaerythritol tetranitrate reductase/0.440
3qlsNDPDihydrofolate reductase1.5.1.30.440
3v0p4GWHisto-blood group ABO system transferase/0.440
4dpf0LGBeta-secretase 13.4.23.460.440
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.440
4j1f1HLBeta-secretase 13.4.23.460.440
4lcjNADC-terminal-binding protein 2/0.440
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.440