Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1xz8 | 5GP | Bifunctional protein PyrR | 2.4.2.9 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1xz8 | 5GP | Bifunctional protein PyrR | 2.4.2.9 | 1.000 | |
2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.527 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.497 | |
2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.496 | |
2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.495 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.494 | |
3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.490 | |
1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.486 | |
3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.486 | |
1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.485 | |
4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.485 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.484 | |
1nzf | UPG | DNA beta-glucosyltransferase | / | 0.483 | |
4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.482 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.480 | |
2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.480 | |
3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.480 | |
3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.480 | |
1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.478 | |
3tr0 | 5GP | Guanylate kinase | / | 0.478 | |
1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.477 | |
3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.477 | |
5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.477 | |
1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.476 | |
2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.476 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.476 | |
3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.476 | |
4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.473 | |
4f9g | C2E | Stimulator of interferon genes protein | / | 0.472 | |
4y9u | NAP | NADPH--cytochrome P450 reductase | / | 0.472 | |
1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.471 | |
2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.471 | |
2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.471 | |
3v2u | ATP | Protein GAL3 | / | 0.471 | |
4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
4kgk | GTP | Uncharacterized protein | / | 0.471 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.470 | |
4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.470 | |
1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.469 | |
3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.469 | |
4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.469 | |
1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.468 | |
1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.468 | |
2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.468 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.468 | |
2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
3hf3 | FMN | Chromate reductase | / | 0.468 | |
3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
4uoc | NCN | CinA-like protein | / | 0.468 | |
1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.467 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.467 | |
2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.467 | |
1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.466 | |
4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.466 | |
3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.465 | |
4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.465 | |
5a3c | NAD | SIR2 family protein | / | 0.465 | |
1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.464 | |
1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.464 | |
1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.464 | |
3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.464 | |
2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.463 | |
2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.463 | |
2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.463 | |
3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.463 | |
4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.463 | |
1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.462 | |
2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.462 | |
2il2 | LIX | Renin | 3.4.23.15 | 0.462 | |
4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.462 | |
1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
2y3s | TIR | TamL | / | 0.461 | |
3cty | FAD | Probable thioredoxin reductase | / | 0.461 | |
3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
3vsw | R31 | Renin | 3.4.23.15 | 0.461 | |
4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.461 | |
1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.460 | |
1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
2c20 | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
2fj1 | CTC | Tetracycline repressor protein class D | / | 0.460 | |
3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.460 | |
4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.460 | |
5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.460 | |
1nzd | UPG | DNA beta-glucosyltransferase | / | 0.459 | |
1r2j | FAD | FkbI | / | 0.459 | |
1zgv | 501 | Prothrombin | 3.4.21.5 | 0.459 | |
2g1s | 4IG | Renin | 3.4.23.15 | 0.459 | |
2hfu | MEV | Mevalonate kinase | / | 0.459 | |
4blr | UTP | NTPase P4 | / | 0.459 | |
4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.459 | |
4yal | 2AM | NADPH--cytochrome P450 reductase | / | 0.459 | |
1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.458 | |
1kfb | IGP | Tryptophan synthase alpha chain | / | 0.458 | |
1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.458 | |
2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.458 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.458 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.458 | |
3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
3pcr | GTP | ADP-ribosylation factor 6 | / | 0.458 | |
4opg | FDA | Conserved Archaeal protein | / | 0.458 | |
4q71 | FAD | Bifunctional protein PutA | / | 0.458 | |
1bil | 0IU | Renin | 3.4.23.15 | 0.457 | |
1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.457 | |
1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.457 | |
2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.457 | |
2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.457 | |
3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.457 | |
3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.457 | |
3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.457 | |
4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.456 | |
4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.456 | |
1c7o | PPG | Hemolysin | / | 0.455 | |
1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.455 | |
1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
1z4u | PH9 | Polyprotein | / | 0.455 | |
2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.455 | |
2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.455 | |
3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.455 | |
3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.455 | |
3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.455 | |
3tjz | GNP | ADP-ribosylation factor 1 | / | 0.455 | |
3vil | SA0 | Beta-glucosidase | / | 0.455 | |
4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.455 | |
4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.455 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.455 | |
1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.454 | |
1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.454 | |
2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.454 | |
3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.454 | |
4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.454 | |
4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.454 | |
4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
4xr9 | NAD | CalS8 | / | 0.454 | |
1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.453 | |
4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.453 | |
4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.453 | |
4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
3v2y | ML5 | Sphingosine 1-phosphate receptor 1 | / | 0.453 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.452 | |
1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.452 | |
1nb6 | UTP | Genome polyprotein | 2.7.7.48 | 0.452 | |
1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.452 | |
2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.452 | |
2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.452 | |
2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.452 | |
2wb2 | FAD | RE11660p | / | 0.452 | |
2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.452 | |
3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.452 | |
3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.452 | |
4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.452 | |
4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.452 | |
1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
2ed3 | SAH | Diphthine synthase | / | 0.451 | |
2i4q | UA4 | Renin | 3.4.23.15 | 0.451 | |
2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
1xdd | AAY | Integrin alpha-L | / | 0.450 | |
1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.450 | |
2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.450 | |
4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.450 | |
1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.449 | |
1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.449 | |
1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.449 | |
1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.449 | |
2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
2iku | LIY | Renin | 3.4.23.15 | 0.449 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.449 | |
3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.449 | |
3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.449 | |
4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.449 | |
4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.449 | |
5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.449 | |
1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.448 | |
1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.448 | |
1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.448 | |
2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.448 | |
2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.448 | |
2g1n | 1IG | Renin | 3.4.23.15 | 0.448 | |
2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.448 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
3ou2 | SAH | SAM-dependent methyltransferase | / | 0.448 | |
3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.448 | |
4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
5a3b | APR | SIR2 family protein | / | 0.448 | |
1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.447 | |
1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
1rdw | LAR | Actin, alpha skeletal muscle | / | 0.447 | |
1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.447 | |
2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.447 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
3h5u | H5U | Genome polyprotein | 2.7.7.48 | 0.447 | |
3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.447 | |
3qvi | K95 | HAP protein | / | 0.447 | |
3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.447 | |
3u9e | COA | Lmo1369 protein | / | 0.447 | |
4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.447 | |
4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.447 | |
4f5y | C2E | Stimulator of interferon genes protein | / | 0.447 | |
4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.447 | |
4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
4y9r | NAP | NADPH--cytochrome P450 reductase | / | 0.447 | |
1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
1ib6 | NAD | Malate dehydrogenase | / | 0.446 | |
1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.446 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.446 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.446 | |
3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
3w8r | ACP | Uridine kinase | / | 0.446 | |
3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.446 | |
4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.446 | |
5kwv | ANP | Pantothenate synthetase | / | 0.446 | |
1a5b | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
1bim | 0QB | Renin | 3.4.23.15 | 0.445 | |
1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
1rne | C60 | Renin | 3.4.23.15 | 0.445 | |
2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.445 | |
2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.445 | |
2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.445 | |
2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.445 | |
2qbu | SAH | Precorrin-2 methyltransferase | / | 0.445 | |
2uuk | 897 | Prothrombin | 3.4.21.5 | 0.445 | |
3d91 | REM | Renin | 3.4.23.15 | 0.445 | |
3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.445 | |
3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.445 | |
3vsx | R32 | Renin | 3.4.23.15 | 0.445 | |
3wwm | ADP | [LysW]-aminoadipate kinase | / | 0.445 | |
4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.445 | |
4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.445 | |
4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.445 | |
5hi6 | MTX | Dihydrofolate reductase | / | 0.445 | |
1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.444 | |
1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.444 | |
1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.444 | |
1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.444 | |
2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.444 | |
3r9u | FAD | Thioredoxin reductase | / | 0.444 | |
4fda | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.444 | |
4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
5dp2 | NAP | CurF | / | 0.444 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.443 | |
1njj | ORX | Ornithine decarboxylase | / | 0.443 | |
1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.443 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
1vik | BAY | Gag-Pol polyprotein | / | 0.443 | |
1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.443 | |
2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.443 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
3a0t | ADP | Sensor histidine kinase | / | 0.443 | |
3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.443 | |
3upi | 0C2 | Genome polyprotein | 2.7.7.48 | 0.443 | |
4b4v | L34 | Bifunctional protein FolD | / | 0.443 | |
4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.443 | |
5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
5cyo | GDP | Septin-9 | / | 0.443 | |
1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
2dra | ATP | CCA-adding enzyme | 2.7.7.72 | 0.442 | |
2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
3atz | FMN | Prostaglandin F2a synthase | / | 0.442 | |
3bsa | 1PD | Genome polyprotein | 2.7.7.48 | 0.442 | |
3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.442 | |
3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4btu | 6XS | Coagulation factor X | 3.4.21.6 | 0.442 | |
4e32 | DWN | Methyltransferase | / | 0.442 | |
4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
4yqf | GDP | Septin-9 | / | 0.442 | |
1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.441 | |
1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.441 | |
1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.441 | |
1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.441 | |
2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.441 | |
2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.441 | |
2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.441 | |
2zhe | 13U | Prothrombin | 3.4.21.5 | 0.441 | |
3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.441 | |
3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
3i0p | NAD | Malate dehydrogenase, putative | / | 0.441 | |
3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.441 | |
5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1mxf | MTX | Putative pteridine reductase 2 | / | 0.440 | |
1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.440 | |
2q14 | ADP | Phosphohydrolase | / | 0.440 | |
2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.440 | |
3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.440 | |
3b1d | PLS | BetaC-S lyase | / | 0.440 | |
3f63 | GTX | Glutathione transferase GST1-4 | / | 0.440 | |
3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.440 | |
3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.440 | |
4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
4lcj | NAD | C-terminal-binding protein 2 | / | 0.440 | |
5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 |