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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1m76CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.35

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1m76CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.351.000
1f0yCAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.774
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.706
2givACOHistone acetyltransferase KAT8/0.514
4l8u9AZSerum albumin/0.513
1bwlFMNNADPH dehydrogenase 11.6.99.10.512
5bsfNADPyrroline-5-carboxylate reductase/0.499
2hcdBIVVitamin D3 receptor A/0.492
1rx8NAPDihydrofolate reductase1.5.1.30.487
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.487
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.487
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.485
3fwiCAMCamphor 5-monooxygenase1.14.15.10.484
2ou2ACOHistone acetyltransferase KAT5/0.482
3oibFDAPutative acyl-CoA dehydrogenase/0.482
1mjbACOHistone acetyltransferase ESA1/0.481
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.481
1vi2NADQuinate/shikimate dehydrogenase/0.481
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.481
1xuoLA1Integrin alpha-L/0.480
3tk3CPZCytochrome P450 2B41.14.14.10.480
4ejmNAPPutative zinc-binding dehydrogenase/0.480
4gah0ETAcyl-coenzyme A thioesterase THEM43.1.2.20.480
1w2xRCPAcetyl-CoA carboxylase/0.479
3nxxNDPDihydrofolate reductase1.5.1.30.479
4b4oNDPEpimerase family protein SDR39U1/0.479
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.478
4g3rCAMCamphor 5-monooxygenase1.14.15.10.478
1w4xFADPhenylacetone monooxygenase1.14.13.920.477
4cd2FOLDihydrofolate reductase1.5.1.30.477
4g47TZFMycocyclosin synthase1.14.21.90.476
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.475
2uxoTACHTH-type transcriptional regulator TtgR/0.475
4i02CMPcAMP-activated global transcriptional regulator CRP/0.475
4xldBRLPeroxisome proliferator-activated receptor gamma/0.475
2x8hFADThioredoxin glutathione reductase/0.474
1bwkFMNNADPH dehydrogenase 11.6.99.10.473
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.473
3b70NAPEnoyl reductase LovC10.473
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.473
1u3dFADCryptochrome-1/0.472
2x8gFADThioredoxin glutathione reductase/0.472
3gqvNAPEnoyl reductase LovC10.472
3ibdCPZCytochrome P450 2B61.14.130.472
3nr4PYVAbscisic acid receptor PYL2/0.472
2qk8MTXDihydrofolate reductase/0.471
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.471
3to6LYS_CMCHistone acetyltransferase ESA1/0.471
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.471
4hxyNDPPlm1/0.471
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.470
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.470
1uzwCDHIsopenicillin N synthase1.21.3.10.470
1yc2NADNAD-dependent protein deacylase 2/0.470
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.470
3l0lHC3Nuclear receptor ROR-gamma/0.470
4nb6444Nuclear receptor ROR-gamma/0.470
2a94AP0L-lactate dehydrogenase1.1.1.270.469
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.469
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.469
1f20NAPNitric oxide synthase, brain1.14.13.390.468
2q61SF1Peroxisome proliferator-activated receptor gamma/0.468
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3iaeD7KBenzaldehyde lyase/0.468
4g3jVNTLanosterol 14-alpha-demethylase/0.468
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.468
1m78NDPDihydrofolate reductase1.5.1.30.467
1t88CAMCamphor 5-monooxygenase1.14.15.10.467
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
2qblCAMCamphor 5-monooxygenase1.14.15.10.467
2vwqNAPGlucose 1-dehydrogenase/0.467
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
4g95OAGDihydrofolate reductase1.5.1.30.467
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.467
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.467
4y8wSTRSteroid 21-hydroxylase/0.467
5c77SAHProtein arginine N-methyltransferase SFM1/0.467
3dl0AP5Adenylate kinase/0.466
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.466
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.466
4do30LAFatty-acid amide hydrolase 13.5.1.990.466
4kwi1TJReductase homolog/0.466
1k6cMK1Gag-Pol polyprotein3.4.23.160.465
1xddAAYIntegrin alpha-L/0.465
2ylzFADPhenylacetone monooxygenase1.14.13.920.465
3oafOAGDihydrofolate reductase1.5.1.30.465
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4cp4CAMCamphor 5-monooxygenase1.14.15.10.465
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
5eccNAPDehydrofolate reductase type I/0.465
1fm9570Peroxisome proliferator-activated receptor gamma/0.464
1j4jACOAcetyltransferase2.3.10.464
2c27ACOMycothiol acetyltransferase2.3.1.1890.464
2ft9CHDFatty acid-binding protein 2, liver/0.464
3b6zCO7Enoyl reductase LovC10.464
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.464
1fmjRTLRetinol dehydratase/0.463
2feuCAMCamphor 5-monooxygenase1.14.15.10.463
2rhgIGPTryptophan synthase alpha chain/0.463
4q72FADBifunctional protein PutA/0.463
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.463
1hbvGANGag-Pol polyprotein/0.462
1o76CAMCamphor 5-monooxygenase1.14.15.10.462
2a1nCAMCamphor 5-monooxygenase1.14.15.10.462
2ejvNADL-threonine 3-dehydrogenase/0.462
3cppCAMCamphor 5-monooxygenase1.14.15.10.462
3fznD7KBenzoylformate decarboxylase4.1.1.70.462
3zuyTCHTransporter/0.462
4c9pCAMCytochrome P450/0.462
4g48PZBMycocyclosin synthase1.14.21.90.462
5bsgNAPPyrroline-5-carboxylate reductase/0.462
1adfTADAlcohol dehydrogenase E chain1.1.1.10.461
1cbqRE9Cellular retinoic acid-binding protein 2/0.461
1drbMTXDihydrofolate reductase1.5.1.30.461
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.461
1xe55FEPlasmepsin-23.4.23.390.461
1yrcCAMCamphor 5-monooxygenase1.14.15.10.461
2abbFMNPentaerythritol tetranitrate reductase/0.461
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.461
2dhfDZFDihydrofolate reductase1.5.1.30.461
3gbuATPUncharacterized sugar kinase PH14592.7.10.461
3s1dZIRCytokinin dehydrogenase 11.5.99.120.461
4a8v2ANMajor pollen allergen Bet v 1-J/0.461
4fhd0TTSpore photoproduct lyase/0.461
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.461
4lxhC1EAlpha/beta hydrolase fold/0.461
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1qiqACCIsopenicillin N synthase1.21.3.10.460
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
3r9uFADThioredoxin reductase/0.460
3t3r9PLCytochrome P450 2A61.14.130.460
3vt7VDXVitamin D3 receptor/0.460
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.460
5ahsCOAAcyl-CoA dehydrogenase/0.460
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.459
1iyzNDPProbable quinone oxidoreductase/0.459
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.459
1svlADPLarge T antigen3.6.40.459
1t2cNAIL-lactate dehydrogenase1.1.1.270.459
2y0mACOHistone acetyltransferase KAT8/0.459
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.459
4oztP1AEcdysone receptor, putative/0.459
4y93746Tyrosine-protein kinase/0.459
3emlZMAAdenosine receptor A2a/0.459
1o9bNAIQuinate/shikimate dehydrogenase/0.458
1t86CAMCamphor 5-monooxygenase1.14.15.10.458
2gqwFADFerredoxin reductase/0.458
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2huqSAHDiphthine synthase/0.458
2rh9IGPTryptophan synthase alpha chain/0.458
3drcMTXDihydrofolate reductase1.5.1.30.458
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.458
3nj0PYVAbscisic acid receptor PYL2/0.458
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.458
4k9yK9YFocal adhesion kinase 12.7.10.20.458
1e7qNAPGDP-L-fucose synthase/0.457
1i2lDCSAminodeoxychorismate lyase4.1.3.380.457
1tehNADAlcohol dehydrogenase class-31.1.1.10.457
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.457
2w9hTOPDihydrofolate reductase1.5.1.30.457
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.457
4eiyZMAAdenosine receptor A2a/0.457
5jtbZMAAdenosine receptor A2a/0.457
1mjaCOAHistone acetyltransferase ESA1/0.456
1t85CAMCamphor 5-monooxygenase1.14.15.10.456
1w6hTITPlasmepsin-23.4.23.390.456
1xny191Propionyl-CoA carboxylase complex B subunit/0.456
2e08SAHDiphthine synthase/0.456
2uxuNARHTH-type transcriptional regulator TtgR/0.456
2znnS44Peroxisome proliferator-activated receptor alpha/0.456
3d84NDPDihydrofolate reductase1.5.1.30.456
3fwjCAMCamphor 5-monooxygenase1.14.15.10.456
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
4dc0NDPPutative ketoacyl reductase1.3.10.456
4m83ERYOleandomycin glycosyltransferase2.4.10.456
4yfy1YJVioF/0.456
1mj9COAHistone acetyltransferase ESA1/0.455
1vf3GDNGlutathione S-transferase 32.5.1.180.455
2po7CHDFerrochelatase, mitochondrial4.99.1.10.455
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.455
2rlcCHDCholoylglycine hydrolase3.5.1.240.455
2znq401Peroxisome proliferator-activated receptor delta/0.455
3hwrNDP2-dehydropantoate 2-reductase/0.455
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.455
4o2bLOCTubulin beta-2B chain/0.455
1bwsNDPGDP-L-fucose synthase/0.454
1diuBDMDihydrofolate reductase1.5.1.30.454
1j21ATPArgininosuccinate synthase/0.454
1meiMOAInosine-5'-monophosphate dehydrogenase/0.454
1osvCHCBile acid receptor/0.454
1pkfEPDEpothilone C/D epoxidase1.140.454
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.454
1rb3MTXDihydrofolate reductase1.5.1.30.454
2c12FADNitroalkane oxidase1.7.3.10.454
2drcMTXDihydrofolate reductase1.5.1.30.454
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.454
2ijmATPFocal adhesion kinase 12.7.10.20.454
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.454
3fwfCAMCamphor 5-monooxygenase1.14.15.10.454
3r4b74TGag-Pol polyprotein/0.454
3vucHHERenin3.4.23.150.454
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.454
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.453
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.453
1phhFADp-hydroxybenzoate hydroxylase/0.453
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
1u3cFADCryptochrome-1/0.453
2c29NAPDihydroflavonol 4-reductase/0.453
2gjlFMNNitronate monooxygenase1.13.12.160.453
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.453
2uxpCLMHTH-type transcriptional regulator TtgR/0.453
2y3rTRKTamL/0.453
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.453
3ieuGDPGTPase Era/0.453
3sx2NADUncharacterized protein/0.453
3t2zFADSulfide-quinone reductase/0.453
4bfvZVVPantothenate kinase2.7.1.330.453
4bfxZVXPantothenate kinase2.7.1.330.453
4k28NADShikimate dehydrogenase family protein/0.453
4ktkKTKCytochrome P450/0.453
4l4fCAMCamphor 5-monooxygenase1.14.15.10.453
4rvnCOAPhenylacetate-coenzyme A ligase/0.453
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.453
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.453
6cp4CAMCamphor 5-monooxygenase1.14.15.10.453
1fmlRTLRetinol dehydratase/0.452
2bxmIMNSerum albumin/0.452
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.452
2rhrEMOPutative ketoacyl reductase1.3.10.452
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.452
2y60M8FIsopenicillin N synthase1.21.3.10.452
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.452
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.452
3gobHXXDdmC/0.452
3h4vNAPPteridine reductase 11.5.1.330.452
3wsbRWZFarnesyltransferase, putative/0.452
4r20AERCytochrome P450 family 17 polypeptide 2/0.452
1c6yMK1Protease/0.451
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.451
1jpaANPEphrin type-B receptor 22.7.10.10.451
1phgMYTCamphor 5-monooxygenase1.14.15.10.451
2a1oCAMCamphor 5-monooxygenase1.14.15.10.451
2ahrNAPPyrroline-5-carboxylate reductase/0.451
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.451
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.451
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
3stuDK3Methylketone synthase I/0.451
4dxhNAJAlcohol dehydrogenase E chain1.1.1.10.451
4gyiADPUncharacterized protein/0.451
4h9506UDihydrofolate reductase1.5.1.30.451
4ktl1CQCytochrome P450/0.451
4q71FADBifunctional protein PutA/0.451
4q73FADBifunctional protein PutA/0.451
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.451
4zohFADPutative oxidoreductase FAD-binding subunit/0.451
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
5iua6DXAdenosine receptor A2a/0.451
1a72PADAlcohol dehydrogenase E chain1.1.1.10.450
1hb1OCVIsopenicillin N synthase1.21.3.10.450
1iwjCAMCamphor 5-monooxygenase1.14.15.10.450
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.450
1j49NADD-lactate dehydrogenase1.1.1.280.450
1me6IVSPlasmepsin-23.4.23.390.450
1vyrFMNPentaerythritol tetranitrate reductase/0.450
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.450
2owvSAHDiphthine synthase/0.450
2p33J07Mitogen-activated protein kinase 102.7.11.240.450
2pcaSAHDiphthine synthase/0.450
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.450
3hllI45Mitogen-activated protein kinase 14/0.450
3imeBZ2Pantothenate synthetase6.3.2.10.450
3ixp834Ecdysone receptor/0.450
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.450
3qlsNDPDihydrofolate reductase1.5.1.30.450
3qm4PN0Cytochrome P450 2D6/0.450
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.450
4cnkFADL-amino acid oxidase/0.450
4wqmFADToluene-4-monooxygenase electron transfer component1.18.1.30.450
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.450
1eyqNARChalcone--flavonone isomerase 15.5.1.60.449
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1meiXMPInosine-5'-monophosphate dehydrogenase/0.449
1pmn984Mitogen-activated protein kinase 102.7.11.240.449
1rx1NAPDihydrofolate reductase1.5.1.30.449
1tvrTB9Gag-Pol polyprotein2.7.7.490.449
1vikBAYGag-Pol polyprotein/0.449
2gr1FADFerredoxin reductase/0.449
2gs7ANPEpidermal growth factor receptor2.7.10.10.449
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3poz03PEpidermal growth factor receptor2.7.10.10.449
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4g2gTDHMycocyclosin synthase1.14.21.90.449
4hy6FJ1Heat shock protein HSP 90-alpha/0.449
4kigENOPhenylpyruvate C(3)-methyltransferase2.1.1.2810.449
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
1hfqMOTDihydrofolate reductase1.5.1.30.448
1jioDEB6-deoxyerythronolide B hydroxylase/0.448
1k8y13PTryptophan synthase alpha chain/0.448
1rd7FOLDihydrofolate reductase1.5.1.30.448
1rx7FOLDihydrofolate reductase1.5.1.30.448
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.448
1x8lOXRRetinol dehydratase/0.448
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.448
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2qbnCAMCamphor 5-monooxygenase1.14.15.10.448
3elm24FCollagenase 33.4.240.448
3p9tTCLRepressor/0.448
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.448
3v3m0ENReplicase polyprotein 1a3.4.19.120.448
3vqsJT1Genome polyprotein/0.448
4dpwAGSMevalonate diphosphate decarboxylase/0.448
4g7gVFVLanosterol 14-alpha-demethylase/0.448
4kcfAKMFAD-dependent oxidoreductase/0.448
1blzACVIsopenicillin N synthase1.21.3.10.447
1jipKTN6-deoxyerythronolide B hydroxylase/0.447
1k6vXN2Gag-Pol polyprotein3.4.23.160.447
1udaUFGUDP-glucose 4-epimerase5.1.3.20.447
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
2cjpVPREpoxide hydrolase/0.447
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.447
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.447
2ien017Gag-Pol polyprotein3.4.23.160.447
2npaMMBPeroxisome proliferator-activated receptor alpha/0.447
2wgjVGHHepatocyte growth factor receptor2.7.10.10.447
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.447
3gwfFADCyclohexanone monooxygenase/0.447
3il1B5DGlutamate receptor 2/0.447
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.447
3s79ASDAromatase1.14.14.140.447
4dbzNDPPutative ketoacyl reductase1.3.10.447
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4e5yNDPGDP-L-fucose synthase1.1.1.2710.447
4loi1YCStimulator of interferon genes protein/0.447
4mkhAP5Adenylate kinase/0.447
4qaiFMNNADPH dehydrogenase/0.447
4tmcFMNOld yellow enzyme/0.447
4yswFADXanthine dehydrogenase/oxidase/0.447
5cyoGDPSeptin-9/0.447
8catNDPCatalase1.11.1.60.447
5k2cZMAAdenosine receptor A2a/0.447
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.446
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.446
1crbRTLRetinol-binding protein 1/0.446
1dz4CAMCamphor 5-monooxygenase1.14.15.10.446
1m9m6NINitric oxide synthase, endothelial1.14.13.390.446
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1qjfACSIsopenicillin N synthase1.21.3.10.446
1tdrMTXDihydrofolate reductase1.5.1.30.446
1zgv501Prothrombin3.4.21.50.446
2m56CAMCamphor 5-monooxygenase1.14.15.10.446
3adaNADSubunit alpha of sarocosine oxidase/0.446
3eldSFGMethyltransferase/0.446
3n0hTOPDihydrofolate reductase1.5.1.30.446
3oxv478Gag-Pol polyprotein3.4.23.160.446
3qsaTA7Anthranilate phosphoribosyltransferase/0.446
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
3vt5YI2Vitamin D3 receptor/0.446
4a802ANMajor pollen allergen Bet v 1-A/0.446
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.446
4iq71G9Mycocyclosin synthase1.14.21.90.446
4l4dCAMCamphor 5-monooxygenase1.14.15.10.446
4opiFDAConserved Archaeal protein/0.446
1b2lNDCAlcohol dehydrogenase1.1.1.10.445
1bil0IURenin3.4.23.150.445
1dz6CAMCamphor 5-monooxygenase1.14.15.10.445
1eupASD6-deoxyerythronolide B hydroxylase/0.445
1ie4T44Transthyretin/0.445
1k6pXN3Gag-Pol polyprotein3.4.23.160.445
1p0hACOMycothiol acetyltransferase2.3.1.1890.445
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.445
1ra8FOLDihydrofolate reductase1.5.1.30.445
1re7FOLDihydrofolate reductase1.5.1.30.445
1xe65FPPlasmepsin-23.4.23.390.445
1y0s331Peroxisome proliferator-activated receptor delta/0.445
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.445
2pmdGNPTranslation initiation factor 2 subunit gamma/0.445
2tprFADTrypanothione reductase1.8.1.120.445
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2vkeTACTetracycline repressor protein class D/0.445
3dxmN24Actin-related protein 3/0.445
3h0aD30Peroxisome proliferator-activated receptor gamma/0.445
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
3pe6ZYHMonoglyceride lipase/0.445
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.445
3tnlNADShikimate dehydrogenase (NADP(+))/0.445
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.445
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.445
4ips1G4Mycocyclosin synthase1.14.21.90.445
4jx1CAHCamphor 5-monooxygenase1.14.15.10.445
4k8aK8AFocal adhesion kinase 12.7.10.20.445
4l4xNDPAmphI/0.445
4la1FADThioredoxin glutathione reductase/0.445
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.444
1dhfFOLDihydrofolate reductase1.5.1.30.444
1dirNADDihydropteridine reductase1.5.1.340.444
1f0xFADD-lactate dehydrogenase1.1.1.280.444
1fy7COAHistone acetyltransferase ESA1/0.444
1pdhFASp-hydroxybenzoate hydroxylase/0.444
1r6g442Thyroid hormone receptor beta/0.444
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.444
1t87CAMCamphor 5-monooxygenase1.14.15.10.444
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.444
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
2cppCAMCamphor 5-monooxygenase1.14.15.10.444
2ejzSAHDiphthine synthase/0.444
2fy4COACholine O-acetyltransferase2.3.1.60.444
2qbmCAMCamphor 5-monooxygenase1.14.15.10.444
2wotZZGTGF-beta receptor type-12.7.11.300.444
3gnqNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
3h8bNSYCathepsin L13.4.22.150.444
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3lqfNADGalactitol dehydrogenase/0.444
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.444
3up0D7SaceDAF-12/0.444
4bfwZVWPantothenate kinase2.7.1.330.444
4dijBLFE3 ubiquitin-protein ligase Mdm26.3.20.444
4i1iNADMalate dehydrogenase/0.444
4ia7BIVVitamin D3 receptor A/0.444
4jldADPAdenylate kinase/0.444
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
4rww2BALmo2692 protein/0.444
4tuvCPZCytochrome P450 1191.140.444
4x5iFOLDihydrofolate reductase1.5.1.30.444
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.444
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.444
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.443
1dr3TAPDihydrofolate reductase1.5.1.30.443
1j39UPGDNA beta-glucosyltransferase/0.443
1jkx138Phosphoribosylglycinamide formyltransferase/0.443
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1orrNADCDP-paratose 2-epimerase/0.443
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.443
2yee2ECHeat shock protein HSP 90-alpha/0.443
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.443
3ijdC2FMethylenetetrahydrofolate reductase/0.443
3mj5GRMReplicase polyprotein 1a3.4.220.443
3mjrAC2Deoxycytidine kinase2.7.1.740.443
3pe2E1BCasein kinase II subunit alpha2.7.11.10.443
3tjsD0RCytochrome P450 3A4/0.443
4a5lNDPThioredoxin reductase/0.443
4a99FADTetX family tetracycline inactivation enzyme/0.443
4emtC2EStimulator of interferon genes protein/0.443
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.443
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.443
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.443
4iah1DXAlr2278 protein/0.443
4nmbFADBifunctional protein PutA/0.443
5d3qGDPDynamin-13.6.5.50.443
1c70L75Protease/0.442
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1hquHBYGag-Pol polyprotein2.7.7.490.442
1kfcIPLTryptophan synthase alpha chain/0.442
1levCLIFructose-1,6-bisphosphatase 13.1.3.110.442
1p8dCO1Oxysterols receptor LXR-beta/0.442
1ppjANYCytochrome b/0.442
1ra3MTXDihydrofolate reductase1.5.1.30.442
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.442
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.442
2h59APRNAD-dependent protein deacetylase/0.442
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.442
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2y37A54Nitric oxide synthase, inducible1.14.13.390.442
2z54AB1Gag-Pol polyprotein3.4.23.160.442
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.442
3fwgCAMCamphor 5-monooxygenase1.14.15.10.442
3icsADPCoenzyme A disulfide reductase/0.442
3in6FMNUncharacterized protein/0.442
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
3p4tFAOPutative acyl-CoA dehydrogenase/0.442
3q0gBCOProbable enoyl-CoA hydratase echA84.2.1.170.442
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.442
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
3tozNADShikimate dehydrogenase (NADP(+))/0.442
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.442
3wrjCAMCamphor 5-monooxygenase1.14.15.10.442
4a87NARMajor pollen allergen Bet v 1-A/0.442
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4c3yFAD3-ketosteroid dehydrogenase/0.442
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.442
4fv7E94Mitogen-activated protein kinase 12.7.11.240.442
4g67SAHUncharacterized ACR, COG1565 superfamily/0.442
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.442
4i1nFOLDihydrofolate reductase1.5.1.30.442
4jauADPSensor histidine kinase/0.442
4jlj1NMDeoxycytidine kinase2.7.1.740.442
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.442
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.442
4tlzNAPKtzI/0.442
5cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1ai9NDPDihydrofolate reductase1.5.1.30.441
1bzfTMQDihydrofolate reductase1.5.1.30.441
1kkq471Peroxisome proliferator-activated receptor alpha/0.441
1knuYPAPeroxisome proliferator-activated receptor gamma/0.441
1pjkANPCasein kinase II subunit alpha2.7.11.10.441
1w06W05Isopenicillin N synthase1.21.3.10.441
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.441
2e4nSAHDiphthine synthase/0.441
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.441
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.441
2jn3JN3Fatty acid-binding protein, liver/0.441
2p9dSAHDiphthine synthase/0.441
2rewREWPeroxisome proliferator-activated receptor alpha/0.441
2vbdV10Isopenicillin N synthase1.21.3.10.441
2xa4AZ5Tyrosine-protein kinase JAK2/0.441
2xvv9DNSerum albumin/0.441
2z97CAMCamphor 5-monooxygenase1.14.15.10.441
3h0sB38Acetyl-CoA carboxylase/0.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
3lzs017Gag-Pol polyprotein3.4.23.160.441
3o6o94MHeat shock protein 83/0.441
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3s7a684Dihydrofolate reductase1.5.1.30.441
3slkNDPPolyketide synthase extender module 2/0.441
3wmxNADNAD dependent epimerase/dehydratase/0.441
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.441
4eji0QACytochrome P450 2A131.14.14.10.441
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.441
4qe6JN3Bile acid receptor/0.441
1bwcFADGlutathione reductase, mitochondrial1.8.1.70.440
1f123HCHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.440
1h50FMNPentaerythritol tetranitrate reductase/0.440
1h73ANPHomoserine kinase2.7.1.390.440
1ihyAPRGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
1jn0NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.440
1jolFFODihydrofolate reductase1.5.1.30.440
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.440
1pq944BOxysterols receptor LXR-beta/0.440
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1szjNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.90.440
2bi8FADUDP-galactopyranose mutase5.4.99.90.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
2hk9NAPShikimate dehydrogenase (NADP(+))/0.440
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.440
2itnANPEpidermal growth factor receptor2.7.10.10.440
2p6iSAHDiphthine synthase/0.440
3e8xNAPBH1520 protein/0.440
3gc9B45Mitogen-activated protein kinase 112.7.11.240.440
3gvhNADMalate dehydrogenase/0.440
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.440
3ns2PYVAbscisic acid receptor PYL2/0.440
3sa9A68Protease/0.440
3uceNDPDehydrogenase/0.440
3w0aDS5Vitamin D3 receptor/0.440
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.440
3wswNADL-lactate dehydrogenase/0.440
4a2aATPCell division protein FtsA/0.440
4ek1CAMCamphor 5-monooxygenase1.14.15.10.440
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4qi5FADCellobiose dehydrogenase/0.440
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.440
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.440
5dp2NAPCurF/0.440
5k2aZMAAdenosine receptor A2a/0.440