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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5ioqDURFlavin-dependent thymidylate synthase2.1.1.148

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
5ioqDURFlavin-dependent thymidylate synthase2.1.1.1481.000
5iotUMPFlavin-dependent thymidylate synthase2.1.1.1480.564
2oapANPType II secretion system protein (GspE-2)/0.510
2rlcCHDCholoylglycine hydrolase3.5.1.240.508
2zazGK1Mitogen-activated protein kinase 14/0.495
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.491
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.489
1i59ADPChemotaxis protein CheA2.7.13.30.488
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.486
2itwITQEpidermal growth factor receptor2.7.10.10.485
5fknTDCTetracycline repressor protein class D/0.485
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.484
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.484
1z5aADPType 2 DNA topoisomerase 6 subunit B/0.483
3lfzATPUncharacterized protein MJ1225/0.483
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.483
2gr0FADFerredoxin reductase/0.482
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.482
4qms1N1Serine/threonine-protein kinase 242.7.11.10.482
1qy8RDIEndoplasmin/0.481
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.481
2vwqNAPGlucose 1-dehydrogenase/0.481
2uyyNA7Putative oxidoreductase GLYR110.480
3apwDP0Alpha-1-acid glycoprotein 2/0.480
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.479
1sdmADPKinesin heavy chain-like protein/0.479
2briANPUridylate kinase2.7.4.220.479
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.479
1d7yFADFerredoxin reductase/0.478
2ydxSTLMethionine adenosyltransferase 2 subunit beta/0.478
3k6l2BBPeptide deformylase3.5.1.880.478
3q5dGDPAtlastin-13.6.50.478
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.477
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.477
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.475
3daaPDDD-alanine aminotransferase2.6.1.210.475
2ft9CHDFatty acid-binding protein 2, liver/0.474
2g9vIFMGlycogen phosphorylase, muscle form2.4.1.10.474
2gjnFMNNitronate monooxygenase1.13.12.160.474
2olrATPPhosphoenolpyruvate carboxykinase (ATP)/0.474
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.474
2tpsTPSThiamine-phosphate synthase/0.474
2xvu9DNSerum albumin/0.474
2y3sTIRTamL/0.474
3r9iADPSeptum site-determining protein MinD/0.474
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.474
2xkaGSPCell division protein FtsZ/0.473
2z4sADPChromosomal replication initiator protein DnaA/0.473
3s1dZIRCytokinin dehydrogenase 11.5.99.120.473
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.473
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.472
1u4sBIHL-lactate dehydrogenase1.1.1.270.472
2vnjNAPNADPH:ferredoxin reductase/0.472
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.472
5eg3ACPFibroblast growth factor receptor 2/0.472
2zsiGA4Gibberellin receptor GID1A30.471
3juqAJDPhenazine biosynthesis protein A/B/0.471
3m9vTYDFAD-dependent oxidoreductase/0.471
4bizADPSensor histidine kinase CpxA/0.471
4tmcFMNOld yellow enzyme/0.471
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.470
3ed1GA3Gibberellin receptor GID1/0.470
3b2sB2STrichothecene 3-O-acetyltransferase/0.469
3zvuA8SAbscisic acid receptor PYR1/0.469
4hjoAQ4Epidermal growth factor receptor2.7.10.10.469
1vyrFMNPentaerythritol tetranitrate reductase/0.468
3r6c17NAnthranilate phosphoribosyltransferase/0.468
4bvaT3Ketimine reductase mu-crystallin1.5.1.250.468
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
1joaFADNADH peroxidase1.11.1.10.467
2ylrNAPPhenylacetone monooxygenase1.14.13.920.467
4ig01FGGag-Pol polyprotein2.7.7.490.467
1bygSTUTyrosine-protein kinase CSK/0.466
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.466
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.466
3ea0ATPATPase, ParA family/0.466
3lu6IMXSerum albumin/0.466
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.466
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.466
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.466
2dpxGDPGTP-binding protein RAD/0.465
2gn6UD1UDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.465
2qo9ANPEphrin type-A receptor 32.7.10.10.465
4jloADPAdenylate kinase/0.465
1m17AQ4Epidermal growth factor receptor2.7.10.10.464
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.464
2ax4ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 22.7.1.250.464
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.464
2zshGA3Gibberellin receptor GID1A30.464
4k5sPM0Oxygenase/0.464
4x8oAP5Adenylate kinase/0.464
1h47C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.463
1i58ADPChemotaxis protein CheA2.7.13.30.463
1nzfUPGDNA beta-glucosyltransferase/0.463
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.463
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.463
2bjfDXCCholoylglycine hydrolase3.5.1.240.463
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.463
2g5cNADPrephenate dehydrogenase/0.463
2j5xGSPADP-ribosylation factor 6/0.463
2ohvNHLGlutamate racemase/0.463
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.463
2xh9J01Uncharacterized protein/0.463
3gbuATPUncharacterized sugar kinase PH14592.7.10.463
3kc02T5Fructose-1,6-bisphosphatase 13.1.3.110.463
3p62FMNPentaerythritol tetranitrate reductase/0.463
4eqcXR1Serine/threonine-protein kinase PAK 12.7.11.10.463
4i02CMPcAMP-activated global transcriptional regulator CRP/0.463
1x2hLPALipoate-protein ligase A6.3.1.200.462
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.462
3ac2KSETyrosine-protein kinase Lck2.7.10.20.462
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.462
4fd2ADPChaperone protein ClpB/0.462
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.462
4riyADPEpidermal growth factor receptor2.7.10.10.462
4xvuATPATPase GET3/0.462
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.461
2w8rADPSuccinate-semialdehyde dehydrogenase, mitochondrial1.2.1.240.461
3enkUPGUDP-glucose 4-epimerase/0.461
3rv6VAESalicylate synthase/0.461
4z17PEPEnolase/0.461
2y4gTIRTamL/0.460
2yegXQGHeat shock protein HSP 90-alpha/0.460
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.460
3d2rADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.460
3eblGA4Gibberellin receptor GID1/0.460
3froNHFGlgA glycogen synthase/0.460
3lpfZ77Beta-glucuronidase3.2.1.310.460
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.460
4affATPNitrogen regulatory protein P-II/0.460
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.460
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.460
1zoyUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.459
1zoyUQ1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.459
2bxmIMNSerum albumin/0.459
2dzbHH2Dihydropteroate synthase/0.459
3w8rACPUridine kinase/0.459
4dpuAGSMevalonate diphosphate decarboxylase/0.459
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4l4eCAMCamphor 5-monooxygenase1.14.15.10.459
4z875GPInosine-5'-monophosphate dehydrogenase/0.459
1c3eNHRPhosphoribosylglycinamide formyltransferase/0.458
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.458
1omoNADAlanine dehydrogenase/0.458
2a7r5GPGMP reductase 2/0.458
2ad5ADPCTP synthase/0.458
2cjfRP43-dehydroquinate dehydratase4.2.1.100.458
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3fwyADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein/0.458
3h06VBPGlutamate receptor 2/0.458
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.458
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.458
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.458
1nhhANPDNA mismatch repair protein MutL/0.457
1nzdUPGDNA beta-glucosyltransferase/0.457
1wvgCXYCDP-glucose 4,6-dehydratase4.2.1.450.457
2gr0ADPFerredoxin reductase/0.457
2j2pSC2Ficolin-2/0.457
2q46NAPUncharacterized protein At5g02240/0.457
2x3fAPCPantothenate synthetase/0.457
3kh5ADPUncharacterized protein MJ1225/0.457
3tnlNADShikimate dehydrogenase (NADP(+))/0.457
4yvz3ATDNA integrity scanning protein DisA/0.457
5hg0SAMPantothenate synthetase/0.457
5iw5NMNNADH pyrophosphatase/0.457
5kgpACOPredicted acetyltransferase/0.457
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.456
1mjaCOAHistone acetyltransferase ESA1/0.456
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.456
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.456
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.456
2r26CMCCitrate synthase2.3.3.160.456
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.456
3t50FMNBlue-light-activated histidine kinase2.7.13.30.456
4dieC5PCytidylate kinase/0.456
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4oagADPMitochondrial dynamics protein MID51/0.456
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.456
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.455
2e2qADPATP-dependent hexokinase/0.455
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.455
2fypRDEEndoplasmin/0.455
3cvuFADRE11660p/0.455
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3h86AP5Adenylate kinase/0.455
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.455
3o153NMThiamine-phosphate synthase/0.455
4e5nNADPhosphonate dehydrogenase1.20.1.10.455
4eftEFTHeat shock protein HSP 90-alpha/0.455
4ek1CAMCamphor 5-monooxygenase1.14.15.10.455
4fhd0TTSpore photoproduct lyase/0.455
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.455
4gqtADPHeat shock protein 90/0.455
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.455
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1i59ANPChemotaxis protein CheA2.7.13.30.454
1noiNTZGlycogen phosphorylase, muscle form2.4.1.10.454
1t02LVA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.454
1txtCAAHMG-CoA synthase/0.454
2bi4NADLactaldehyde reductase1.1.1.770.454
2gr1FADFerredoxin reductase/0.454
3p67FMNPentaerythritol tetranitrate reductase/0.454
4e07ACPPlasmid partitioning protein ParF/0.454
4jxrACOAcetyltransferase/0.454
4l4fCAMCamphor 5-monooxygenase1.14.15.10.454
5kwvANPPantothenate synthetase/0.454
1g4tFTPThiamine-phosphate synthase/0.453
1i5cADPChemotaxis protein CheA2.7.13.30.453
1p9wANPType II secretion system protein E/0.453
2bl4NADLactaldehyde reductase1.1.1.770.453
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.453
2py7ATPPhosphoenolpyruvate carboxykinase (ATP)/0.453
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.453
2rhgIGPTryptophan synthase alpha chain/0.453
2yvfNADFerredoxin reductase/0.453
2zfaFMNLactate oxidase/0.453
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.453
3d8vUD1Bifunctional protein GlmU/0.453
3lm8VIBThiamine pyrophosphokinase2.7.6.20.453
3mpt1GKMitogen-activated protein kinase 14/0.453
3qsaTA7Anthranilate phosphoribosyltransferase/0.453
4yqfGDPSeptin-9/0.453
1hzjUD1UDP-glucose 4-epimerase/0.452
1i3nUD1UDP-glucose 4-epimerase/0.452
1i5bANPChemotaxis protein CheA2.7.13.30.452
1odjGMPPurine nucleoside phosphorylase/0.452
2bueCOAAAC(6')-Ib/0.452
2cmoM1LGlutamate receptor 2/0.452
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.452
2xpwOTCTetracycline repressor protein class D/0.452
2y6o1N1Ephrin type-A receptor 42.7.10.10.452
2yn8STUEphrin type-B receptor 42.7.10.10.452
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.452
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4f6w0SSCyclin-dependent kinase 82.7.11.220.452
4fk1FADPutative thioredoxin reductase/0.452
4h4yNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.452
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.452
4pmjNAPPutative oxidoreductase/0.452
1cozCTPGlycerol-3-phosphate cytidylyltransferase2.7.7.390.451
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
1fp6ADPNitrogenase iron protein 11.18.6.10.451
1hdrNADDihydropteridine reductase1.5.1.340.451
2acxANPG protein-coupled receptor kinase 62.7.11.160.451
2f3rG5PGuanylate kinase2.7.4.80.451
2feuCAMCamphor 5-monooxygenase1.14.15.10.451
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.451
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.451
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.451
3f3sNADLambda-crystallin homolog/0.451
3ivgFG5Pantothenate synthetase6.3.2.10.451
3lqsPSZD-alanine aminotransferase2.6.1.210.451
3sxnCOAN-acetyltransferase Eis/0.451
4yp12BAStimulator of interferon genes protein/0.451
1bwlFMNNADPH dehydrogenase 11.6.99.10.450
1f5nGNPGuanylate-binding protein 1/0.450
1gldADPGlycerol kinase/0.450
1j21ATPArgininosuccinate synthase/0.450
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.450
2g8yNADHydroxycarboxylate dehydrogenase B/0.450
2p2fCOAAcetyl-coenzyme A synthetase/0.450
2x0rNADMalate dehydrogenase/0.450
3af0GDPPantothenate kinase2.7.1.330.450
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3fwfCAMCamphor 5-monooxygenase1.14.15.10.450
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4hnhNAPNAD-dependent epimerase/dehydratase/0.450
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.450
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.450
4n57ADPAPH(2'')-Id/0.450
4ot2NPSSerum albumin/0.450
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.450
4ww4ADPRuvB-like helicase/0.450
1esmCOAPantothenate kinase2.7.1.330.449
1i6lTYMTryptophan--tRNA ligase6.1.1.20.449
1j39UPGDNA beta-glucosyltransferase/0.449
1nm1ATPMajor actin/0.449
1ot7CHCBile acid receptor/0.449
1qm5PLPMaltodextrin phosphorylase2.4.1.10.449
1udbUFGUDP-glucose 4-epimerase5.1.3.20.449
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.449
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
2dbzNAPGlyoxylate reductase1.1.1.260.449
2hk9NAPShikimate dehydrogenase (NADP(+))/0.449
2i7pACOPantothenate kinase 32.7.1.330.449
2ojg19AMitogen-activated protein kinase 12.7.11.240.449
2qimZEAClass 10 plant pathogenesis-related protein/0.449
2wb2FADRE11660p/0.449
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.449
3a4vNADNDP-sugar epimerase/0.449
3ahiHTLProbable phosphoketolase/0.449
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3l6jZ90Alr2278 protein/0.449
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.449
4fryNADPutative signal-transduction protein with CBS domains/0.449
4i1iNADMalate dehydrogenase/0.449
4lg5A1OAbscisic acid receptor PYL2/0.449
4pd6URINucleoside permease/0.449
1ae1NAPTropinone reductase 1/0.448
1hk3T44Serum albumin/0.448
1mf0GDPAdenylosuccinate synthetase isozyme 1/0.448
1qo8FADFumarate reductase flavoprotein subunit/0.448
1rdwLARActin, alpha skeletal muscle/0.448
1udaUFGUDP-glucose 4-epimerase5.1.3.20.448
1w5sADPORC1-type DNA replication protein 2/0.448
1w6hTITPlasmepsin-23.4.23.390.448
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.448
2ds11CDCyclin-dependent kinase 22.7.11.220.448
2ibzUQ6Cytochrome b/0.448
2iskFNR5,6-dimethylbenzimidazole synthase1.13.11.790.448
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2wi72KLHeat shock protein HSP 90-alpha/0.448
2xf3J01Uncharacterized protein/0.448
2xfsJ01Uncharacterized protein/0.448
2xyuQ9GEphrin type-A receptor 42.7.10.10.448
2zbaZBATrichothecene 3-O-acetyltransferase/0.448
3fskRO6Mitogen-activated protein kinase 14/0.448
3fwjCAMCamphor 5-monooxygenase1.14.15.10.448
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.448
3mvm39PMitogen-activated protein kinase 14/0.448
3q9lATPSeptum site-determining protein MinD/0.448
3smkCW714-3-3 protein sigma/0.448
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.448
3ujlA8SAbscisic acid receptor PYL2/0.448
3uu114BAnthranilate phosphoribosyltransferase/0.448
4aosNAPSteroid monooxygenase/0.448
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.448
4dpwAGSMevalonate diphosphate decarboxylase/0.448
4iawLIZNeutrophil gelatinase-associated lipocalin/0.448
4m5pFMNNADPH dehydrogenase/0.448
4xgxADPFAD:protein FMN transferase/0.448
5c8yACPTubulin tyrosine ligase/0.448
5iqhGNPBifunctional AAC/APH2.3.10.448
1f3pNADFerredoxin reductase/0.447
1hk5T44Serum albumin/0.447
1i5aACPChemotaxis protein CheA2.7.13.30.447
1mdlRMNMandelate racemase/0.447
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.447
1u1gBBBUridine phosphorylase2.4.2.30.447
1uyuCAMCamphor 5-monooxygenase1.14.15.10.447
1xkdNAPIsocitrate dehydrogenase [NADP]/0.447
2qbnCAMCamphor 5-monooxygenase1.14.15.10.447
2rg6287Mitogen-activated protein kinase 14/0.447
2yj5ATPCopper-transporting ATPase/0.447
2ykeYKEHeat shock protein HSP 90-alpha/0.447
3cgdFADCoenzyme A disulfide reductase/0.447
3copADPGlycogen synthase2.4.1.210.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3e6yCW114-3-3-like protein C/0.447
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.447
3junAKDPhenazine biosynthesis protein A/B/0.447
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.447
3ojiPYVAbscisic acid receptor PYL3/0.447
3vglANPGlucokinase/0.447
4at8ATPInterleukin enhancer-binding factor 2/0.447
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
4du82P0Mevalonate diphosphate decarboxylase/0.447
4dzzADPPlasmid partitioning protein ParF/0.447
4ead0NPThymidine phosphorylase2.4.2.40.447
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4gncASORegucalcin3.1.1.170.447
4la7A1OAbscisic acid receptor PYL2/0.447
5cyoGDPSeptin-9/0.447
5fs9FADApoptosis-inducing factor 1, mitochondrial1.1.10.447
1a5bIGPTryptophan synthase alpha chain/0.446
1hk1T44Serum albumin/0.446
1i58ACPChemotaxis protein CheA2.7.13.30.446
1lrkUD1UDP-glucose 4-epimerase5.1.3.20.446
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.446
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.446
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.446
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2czfXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.446
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.446
2z6dFMNPhototropin-22.7.11.10.446
3iocA5DPantothenate synthetase6.3.2.10.446
3kr4BESM17 leucyl aminopeptidase/0.446
3r9uFADThioredoxin reductase/0.446
4a5lNDPThioredoxin reductase/0.446
4dptAGSMevalonate diphosphate decarboxylase/0.446
4dpy2P0Mevalonate diphosphate decarboxylase/0.446
4ffrATPUncharacterized protein/0.446
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.446
4oztP1AEcdysone receptor, putative/0.446
4zolACPTubulin tyrosine ligase/0.446
1bwsNDPGDP-L-fucose synthase/0.445
1cjvDADAdenylate cyclase type 2/0.445
1cjvDADAdenylate cyclase type 5/0.445
1esvLARActin, alpha skeletal muscle/0.445
1hfqMOTDihydrofolate reductase1.5.1.30.445
1rkxNADCDP-D-glucose-4,6-dehydratase/0.445
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1z7eUGABifunctional polymyxin resistance protein ArnA/0.445
2bhiSFTCytotoxin 3/0.445
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.445
2ggqTTPDual sugar-1-phosphate nucleotidylyltransferase/0.445
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.445
2qtvGNPSmall COPII coat GTPase SAR13.6.50.445
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2y3rTRKTamL/0.445
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.445
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
3junAJDPhenazine biosynthesis protein A/B/0.445
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.445
3nmnPYVAbscisic acid receptor PYL1/0.445
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.445
4ejmNAPPutative zinc-binding dehydrogenase/0.445
4g2fC07Ephrin type-A receptor 32.7.10.10.445
4i1nFOLDihydrofolate reductase1.5.1.30.445
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.445
4k10NI9Farnesyl pyrophosphate synthase/0.445
4k9u5AWCytochrome P450 3A4/0.445
4loh1SYStimulator of interferon genes protein/0.445
4wriOKAOkadaic acid binding protein 2-alpha/0.445
5j23A2RPutative 2-hydroxyacid dehydrogenase/0.445
1df7MTXDihydrofolate reductase1.5.1.30.444
1eioGCHGastrotropin/0.444
1g2aBB2Peptide deformylase3.5.1.880.444
1glbADPGlycerol kinase/0.444
1kp2ATPArgininosuccinate synthase6.3.4.50.444
1mezGDPAdenylosuccinate synthetase isozyme 1/0.444
1t09NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
1v3sATPSignaling protein/0.444
1wuuANPGalactokinase2.7.1.60.444
2bt0CT5Heat shock protein HSP 90-alpha/0.444
2bz5AB4Heat shock protein HSP 90-alpha/0.444
2hchN5AEndoplasmin/0.444
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.444
2nnqT4BFatty acid-binding protein, adipocyte/0.444
2nr4FMNConserved protein/0.444
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2qocANPEphrin type-A receptor 32.7.10.10.444
2rkiTT1Gag-Pol polyprotein2.7.7.490.444
2vwhNAPGlucose 1-dehydrogenase/0.444
2wq6FADRE11660p/0.444
2ya3J7V5'-AMP-activated protein kinase subunit gamma-1/0.444
3a1eACPProbable copper-exporting P-type ATPase A3.6.3.540.444
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3cisATPUniversal stress protein Rv2623/0.444
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.444
3orfNADDihydropteridine reductase1.5.1.340.444
3p82FMNPentaerythritol tetranitrate reductase/0.444
3rasNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
4eepFMNPhototropin-22.7.11.10.444
4eesFMNPhototropin-22.7.11.10.444
4nl4ADPPrimosomal protein N'/0.444
5a3cNADSIR2 family protein/0.444
1aylATPPhosphoenolpyruvate carboxykinase (ATP)/0.443
1gc5ADPADP-dependent glucokinase2.7.1.1470.443
1h6vNDPThioredoxin reductase 1, cytoplasmic1.8.1.90.443
1hkuNADC-terminal-binding protein 11.1.10.443
1kfbIGPTryptophan synthase alpha chain/0.443
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.443
1w5tANPORC1-type DNA replication protein 2/0.443
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.443
2bt4CA23-dehydroquinate dehydratase4.2.1.100.443
2bxgIBPSerum albumin/0.443
2c6eHPMAurora kinase A2.7.11.10.443
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.443
2p4iMR9Angiopoietin-1 receptor2.7.10.10.443
2ql6ADPNicotinamide riboside kinase 1/0.443
2xpvMIYTetracycline repressor protein class D/0.443
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.443
3akeC5PCytidylate kinase/0.443
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
3ig8ADPGlutamate--cysteine ligase6.3.2.20.443
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3q1kADPD-alanine--D-alanine ligase A6.3.2.40.443
3qs817DAnthranilate phosphoribosyltransferase/0.443
3svj4LIPeptide deformylase/0.443
3tjzGNPADP-ribosylation factor 1/0.443
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4bqwQNMEgl nine homolog 1/0.443
4ed4ATP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.443
4hnc0UTMandelate racemase/0.443
4mvcCDCCholine-phosphate cytidylyltransferase A/0.443
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.443
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4wecNADShort chain dehydrogenase/0.443
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.443
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.442
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.442
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.442
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.442
2cftPLPPyridoxal phosphate phosphatase/0.442
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.442
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.442
2trtTACTetracycline repressor protein class D/0.442
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2vutNADNitrogen metabolite repression protein nmrA/0.442
2y9qANPMitogen-activated protein kinase 12.7.11.240.442
2yvgNADFerredoxin reductase/0.442
3aykCGSInterstitial collagenase3.4.24.70.442
3epoMP5Phosphomethylpyrimidine synthase/0.442
3ioeA7DPantothenate synthetase6.3.2.10.442
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.442
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.442
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.442
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.442
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4bb3KKAIsopenicillin N synthase1.21.3.10.442
4e9aQAPPeptide deformylase/0.442
4eqxFADCoenzyme A disulfide reductase/0.442
4k6fNAPPutative Acetoacetyl-CoA reductase/0.442
4kcfAKMFAD-dependent oxidoreductase/0.442
4o4iACPTubulin tyrosine ligase/0.442
5cwa0GAAnthranilate synthase component 14.1.3.270.442
1b39ATPCyclin-dependent kinase 22.7.11.220.441
1c80GTP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 13.1.3.460.441
1dj3GDPAdenylosuccinate synthetase, chloroplastic/0.441
1qf4RPDAdenylosuccinate synthetase/0.441
1t88CAMCamphor 5-monooxygenase1.14.15.10.441
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.441
2breKJ2ATP-dependent molecular chaperone HSP82/0.441
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.441
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2p2bCOAAcetyl-coenzyme A synthetase/0.441
2piaFMNPhthalate dioxygenase reductase/0.441
2puiADPMethylthioribose kinase2.7.1.1000.441
2zybKSLTyrosine-protein kinase Lck2.7.10.20.441
3aezGDPPantothenate kinase2.7.1.330.441
3b2eADPATPase GET3/0.441
3c1y2BADNA integrity scanning protein DisA/0.441
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.441
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
3isjA8DPantothenate synthetase6.3.2.10.441
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.441
3qlrNDPDihydrofolate reductase1.5.1.30.441
3s87DGTRibonucleoside-diphosphate reductase large chain 11.17.4.10.441
3stxBKAMethylketone synthase I/0.441
3wecAUICytochrome P450/0.441
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4hjfC2EGGDEF family protein/0.441
4ku3MYA3-oxoacyl-[ACP] synthase III/0.441
4m83ERYOleandomycin glycosyltransferase2.4.10.441
4mv1ADPBiotin carboxylase6.3.4.140.441
4nbwNADShort-chain dehydrogenase/reductase SDR/0.441
4zrnUPGUDP-glucose 4-epimerase, putative/0.441
1daaPLPD-alanine aminotransferase2.6.1.210.440
1gebCAMCamphor 5-monooxygenase1.14.15.10.440
1m76NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.440
1xddAAYIntegrin alpha-L/0.440
1xq6NAPUncharacterized protein At5g02240/0.440
2bpoNAPNADPH--cytochrome P450 reductase/0.440
2h2aDNDProbable nicotinate-nucleotide adenylyltransferase/0.440
2oz6CMPCyclic AMP receptor-like protein/0.440
2qirCOAAminoglycoside 6-N-acetyltransferase type Ib11/0.440
2vaxCSCAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.440
2vbdV10Isopenicillin N synthase1.21.3.10.440
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.440
2xulATPNitrogen regulatory protein P-II/0.440
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.440
3fr4F8AFatty acid-binding protein, adipocyte/0.440
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3jzdNADMaleylacetate reductase/0.440
3kr5BEYM17 leucyl aminopeptidase/0.440
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.440
3wleNAD(R)-specific carbonyl reductase/0.440
4chzH75Integrase/0.440
4d03NAPPhenylacetone monooxygenase1.14.13.920.440
4ddhMS0Pantothenate synthetase6.3.2.10.440
4ebfNADPhosphonate dehydrogenase1.20.1.10.440
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4h6rFDAProline dehydrogenase/0.440
4hj6FMNLOV protein/0.440
4i6gFADCryptochrome-2/0.440
4itmATPTetraacyldisaccharide 4'-kinase/0.440
4jqlVJ6Heat shock protein HSP 90-alpha/0.440
4kf1HT5Aryldialkylphosphatase3.1.8.10.440
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.440
4ku2MYA3-oxoacyl-[ACP] synthase III/0.440
4nmcFADBifunctional protein PutA/0.440
4ocgCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.440
4ohxADPProtein clpf-1/0.440
4qysPLRTryptophan synthase beta chain 24.2.1.200.440
4wouGDPPhosphoenolpyruvate carboxykinase [GTP]/0.440
5ftcADPTPR domain protein/0.440