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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fv7E94Mitogen-activated protein kinase 12.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fv7E94Mitogen-activated protein kinase 12.7.11.241.000
4g3jVNTLanosterol 14-alpha-demethylase/0.507
4fv9E71Mitogen-activated protein kinase 12.7.11.240.495
1bxoPP7Penicillopepsin-13.4.23.200.494
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.494
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.490
4i22IREEpidermal growth factor receptor2.7.10.10.489
1jpaANPEphrin type-B receptor 22.7.10.10.488
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.487
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.486
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.485
1k7l544Peroxisome proliferator-activated receptor alpha/0.485
1y0s331Peroxisome proliferator-activated receptor delta/0.485
3il1B5DGlutamate receptor 2/0.485
3zh8C58Protein kinase C iota type2.7.11.130.485
4g7gVFVLanosterol 14-alpha-demethylase/0.482
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.482
3p7nFMNLight-activated DNA-binding protein EL222/0.481
3b6zCO7Enoyl reductase LovC10.480
4riyADPEpidermal growth factor receptor2.7.10.10.480
2wotZZGTGF-beta receptor type-12.7.11.300.479
1kkq471Peroxisome proliferator-activated receptor alpha/0.478
1xl5190Gag-Pol polyprotein3.4.23.160.478
3p62FMNPentaerythritol tetranitrate reductase/0.478
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.476
3mtfA3FActivin receptor type-12.7.11.300.476
1ma0NADAlcohol dehydrogenase class-31.1.1.10.475
1mjbACOHistone acetyltransferase ESA1/0.475
1zeoC01Peroxisome proliferator-activated receptor gamma/0.475
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.475
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.475
3cgfJNFMitogen-activated protein kinase 102.7.11.240.474
3phiNDPShikimate dehydrogenase (NADP(+))/0.474
4ji91M3Tyrosine-protein kinase JAK2/0.474
1pjkANPCasein kinase II subunit alpha2.7.11.10.473
2p33J07Mitogen-activated protein kinase 102.7.11.240.473
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.473
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.472
3bxrDRRGag-Pol polyprotein3.4.23.160.472
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.472
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.471
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.471
3owj1ELCasein kinase II subunit alpha2.7.11.10.471
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.471
1k6pXN3Gag-Pol polyprotein3.4.23.160.470
1mjaCOAHistone acetyltransferase ESA1/0.470
1yb5NAPQuinone oxidoreductase1.6.5.50.470
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.470
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.470
4ryvZEAProtein LlR18A/0.470
1gqtACPRibokinase/0.469
2ym2FADPhenylacetone monooxygenase1.14.13.920.469
1fy7COAHistone acetyltransferase ESA1/0.468
2zb3NDPProstaglandin reductase 21.3.1.480.468
3eljGS7Mitogen-activated protein kinase 82.7.11.240.468
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.468
4xguADPPutative pachytene checkpoint protein 2/0.468
4c58824Cyclin-G-associated kinase2.7.11.10.467
4egbNADdTDP-glucose 4,6-dehydratase/0.467
4q71FADBifunctional protein PutA/0.467
1drhNAPDihydrofolate reductase1.5.1.30.466
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.466
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.466
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
2p3b3TLV-1 PROTEASE protein/0.466
2p3b3TLV-1 protease/0.466
2q5g1FAPeroxisome proliferator-activated receptor delta/0.466
2xx91NFGlutamate receptor 2/0.466
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.466
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.466
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.465
4qi5FADCellobiose dehydrogenase/0.465
2a94AP0L-lactate dehydrogenase1.1.1.270.464
2abbFMNPentaerythritol tetranitrate reductase/0.464
3gw9VNILanosterol 14-alpha-demethylase/0.464
3nxe2NCProtease/0.464
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.464
1h1r6CPCyclin-dependent kinase 22.7.11.220.463
1tj0FADBifunctional protein PutA1.5.5.20.463
1xddAAYIntegrin alpha-L/0.463
2ebaFADPutative glutaryl-CoA dehydrogenase/0.463
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.463
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.463
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.463
3v9y24LPeroxisome proliferator-activated receptor gamma/0.463
4c02TAKActivin receptor type-12.7.11.300.463
5e92ANPTGF-beta receptor type-22.7.11.300.463
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
1u54ACPActivated CDC42 kinase 1/0.462
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.462
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.462
2qo9ANPEphrin type-A receptor 32.7.10.10.462
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.462
3ibdCPZCytochrome P450 2B61.14.130.462
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.462
4lopSB4Mitogen-activated protein kinase 14/0.462
4mihFADPyranose 2-oxidase1.1.3.100.462
1u4dDBQActivated CDC42 kinase 1/0.461
3iocA5DPantothenate synthetase6.3.2.10.461
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
2w06FRVCyclin-dependent kinase 22.7.11.220.460
3s1dZIRCytokinin dehydrogenase 11.5.99.120.460
4g2fC07Ephrin type-A receptor 32.7.10.10.460
5e8ySTUTGF-beta receptor type-22.7.11.300.460
2om9AJAPeroxisome proliferator-activated receptor gamma/0.459
2ykiYKIHeat shock protein HSP 90-alpha/0.459
3lpkZ76Beta-secretase 13.4.23.460.459
4a84DXCMajor pollen allergen Bet v 1-A/0.459
4d03FADPhenylacetone monooxygenase1.14.13.920.459
4gk2L66Ephrin type-A receptor 32.7.10.10.459
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.459
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.459
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.459
5d3qGDPDynamin-13.6.5.50.459
5e8wSTUTGF-beta receptor type-12.7.11.300.459
1bdlIM1Gag-Pol polyprotein3.4.23.160.458
1daz0Q4Gag-Pol polyprotein3.4.23.160.458
1lf2R37Plasmepsin-23.4.23.390.458
1vikBAYGag-Pol polyprotein/0.458
1zemNADXylitol dehydrogenase/0.458
2dv7SAHDiphthine synthase/0.458
3dd125DGlycogen phosphorylase, liver form2.4.1.10.458
4aotGW8Serine/threonine-protein kinase 102.7.11.10.458
4bb3KKAIsopenicillin N synthase1.21.3.10.458
4dbzNDPPutative ketoacyl reductase1.3.10.458
4o59NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.458
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
2g20L1ARenin3.4.23.150.457
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.457
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.457
2q9fC3SCholesterol 24-hydroxylase/0.457
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.457
2xyuQ9GEphrin type-A receptor 42.7.10.10.457
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.457
3q3cNADNAD-dependent L-serine dehydrogenase/0.457
3t8vBTJM1 family aminopeptidase3.4.110.457
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.457
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.457
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.457
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.457
1bil0IURenin3.4.23.150.456
1bygSTUTyrosine-protein kinase CSK/0.456
1jioDEB6-deoxyerythronolide B hydroxylase/0.456
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1lf3EH5Plasmepsin-23.4.23.390.456
1sbgIM1Gag-Pol polyprotein/0.456
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.456
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.456
3kfs3TLGag-Pol polyprotein/0.456
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.456
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.456
1k6cMK1Gag-Pol polyprotein3.4.23.160.455
1t2cNAIL-lactate dehydrogenase1.1.1.270.455
2ou2ACOHistone acetyltransferase KAT5/0.455
3b70NAPEnoyl reductase LovC10.455
3d8bADPFidgetin-like protein 13.6.40.455
3fcjFADNitroalkane oxidase1.7.3.10.455
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.455
3nwxKVSGag-Pol polyprotein3.4.23.160.455
3uyt0CKCasein kinase I isoform delta2.7.11.10.455
3w32W32Epidermal growth factor receptor2.7.10.10.455
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.455
1bxqPP8Penicillopepsin-13.4.23.200.454
1fxsNAPGDP-L-fucose synthase/0.454
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.454
1mp0NADAlcohol dehydrogenase class-31.1.1.10.454
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.454
1nzdUPGDNA beta-glucosyltransferase/0.454
1rv1IMZE3 ubiquitin-protein ligase Mdm26.3.20.454
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.454
3dogNNNCyclin-dependent kinase 22.7.11.220.454
3ieuGDPGTPase Era/0.454
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4enhFVXCholesterol 24-hydroxylase/0.454
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.454
4gk3L87Ephrin type-A receptor 32.7.10.10.454
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.454
4i8zG08Gag-Pol polyprotein3.4.23.160.454
1bwsNDPGDP-L-fucose synthase/0.453
1cf3FADGlucose oxidase1.1.3.40.453
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.453
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.453
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.453
2gjlFMNNitronate monooxygenase1.13.12.160.453
3cgoJNOMitogen-activated protein kinase 102.7.11.240.453
3e8xNAPBH1520 protein/0.453
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.453
4at0FADPossible succinate dehydrogenase/0.453
4hy6FJ1Heat shock protein HSP 90-alpha/0.453
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.453
5hsaFASAlcohol oxidase 11.1.3.130.453
1v9aSAHUncharacterized protein/0.452
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.452
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.452
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.452
2p83MR0Beta-secretase 13.4.23.460.452
3gxlQIGTGF-beta receptor type-12.7.11.300.452
3ixj586Beta-secretase 13.4.23.460.452
3ixk929Beta-secretase 13.4.23.460.452
3jynNDPQuinone oxidoreductase/0.452
3r83Z14Cyclin-dependent kinase 22.7.11.220.452
4ambDUDPutative glycosyl transferase/0.452
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4dfg0JVGag-Pol polyprotein3.4.23.160.452
4hge15VTyrosine-protein kinase JAK2/0.452
4qnyANPMitogen activated protein kinase, putative/0.452
1hbvGANGag-Pol polyprotein/0.451
1uyePU9Heat shock protein HSP 90-alpha/0.451
2cig1DGDihydrofolate reductase1.5.1.30.451
2ek2SAHDiphthine synthase/0.451
2o0uC0MMitogen-activated protein kinase 102.7.11.240.451
2r43G3GGag-Pol polyprotein3.4.23.160.451
3gu83GUDeath-associated protein kinase 12.7.11.10.451
3kb1ADPIron-sulfur cluster carrier protein/0.451
3qp0NI8Gag-Pol polyprotein3.4.23.160.451
3vt9YI4Vitamin D3 receptor/0.451
3wmxNADNAD dependent epimerase/dehydratase/0.451
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
4a4qUX9Pol protein/0.451
4dymIYZActivin receptor type-12.7.11.300.451
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.451
4kb81QOCasein kinase I isoform delta2.7.11.10.451
4r21STRCytochrome P450 family 17 polypeptide 2/0.451
1bsvNDPGDP-L-fucose synthase/0.450
1hsgMK1Gag-Pol polyprotein/0.450
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.450
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.450
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.450
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.450
2aa0MTPAdenosine kinase2.7.1.200.450
2cen4AHProtease/0.450
2eleSAHDiphthine synthase/0.450
2ghlLIBMitogen-activated protein kinase 14/0.450
2q59240Peroxisome proliferator-activated receptor gamma/0.450
2xhd7T9Glutamate receptor 2/0.450
2xveFADPutative flavin-containing monooxygenase/0.450
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.450
3ad9NADSubunit alpha of sarocosine oxidase/0.450
3oqfS51Renin3.4.23.150.450
3qqgX06Cyclin-dependent kinase 22.7.11.220.450
3wecAUICytochrome P450/0.450
4jbqVX6Aurora kinase A2.7.11.10.450
1g1aNADdTDP-glucose 4,6-dehydratase/0.449
1rdwLARActin, alpha skeletal muscle/0.449
2b7aIZATyrosine-protein kinase JAK2/0.449
2gs7ANPEpidermal growth factor receptor2.7.10.10.449
2npxNADNADH peroxidase1.11.1.10.449
2p5cSAHDiphthine synthase/0.449
2wouZZFTGF-beta receptor type-12.7.11.300.449
2y05NAPProstaglandin reductase 1/0.449
2y0mACOHistone acetyltransferase KAT8/0.449
2znnS44Peroxisome proliferator-activated receptor alpha/0.449
3cib314Beta-secretase 13.4.23.460.449
3h86AP5Adenylate kinase/0.449
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.449
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.449
3ijoB4DGlutamate receptor 2/0.449
3sz0FADSulfide-quinone reductase/0.449
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.449
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.449
4ipw1G7Mycocyclosin synthase1.14.21.90.449
4uymVOR14-alpha sterol demethylase Cyp51B/0.449
1k6tXN1Gag-Pol polyprotein3.4.23.160.448
1nhhANPDNA mismatch repair protein MutL/0.448
2f81017Gag-Pol polyprotein3.4.23.160.448
2owuSAHDiphthine synthase/0.448
2q7vFADThioredoxin reductase/0.448
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.40.448
3ekx1UNGag-Pol polyprotein3.4.23.160.448
3em3478Gag-Pol polyprotein3.4.23.160.448
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.448
3oqkS52Renin3.4.23.150.448
3rpeFADPutative modulator of drug activity/0.448
3t2kFADSulfide-quinone reductase/0.448
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.448
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.448
4kb9G79Protease/0.448
4kwi1TJReductase homolog/0.448
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.448
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.448
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.448
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
1e3eNAIAlcohol dehydrogenase 41.1.1.10.447
1qorNDPQuinone oxidoreductase 1/0.447
1sh9RITGag-Pol polyprotein3.4.23.160.447
1tytFADTrypanothione reductase1.8.1.120.447
1udaUFGUDP-glucose 4-epimerase5.1.3.20.447
1udbUFGUDP-glucose 4-epimerase5.1.3.20.447
1unlRRCCyclin-dependent-like kinase 52.7.11.10.447
1w6hTITPlasmepsin-23.4.23.390.447
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.447
1xe65FPPlasmepsin-23.4.23.390.447
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.447
2e08SAHDiphthine synthase/0.447
2fxeDR7Gag-Pol polyprotein3.4.23.160.447
2hutSAHDiphthine synthase/0.447
2p3d3TLProtease/0.447
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.447
3cr0809Wee1-like protein kinase2.7.10.20.447
3cukFADD-amino-acid oxidase1.4.3.30.447
3i60E86Mitogen-activated protein kinase 12.7.11.240.447
3inxJZCHeat shock protein HSP 90-alpha/0.447
3kduNKSPeroxisome proliferator-activated receptor alpha/0.447
3lpiZ74Beta-secretase 13.4.23.460.447
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.447
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.447
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.447
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.447
5jscFADPutative acyl-CoA dehydrogenase/0.447
1hviA77Protease/0.446
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.446
1rfuADPPyridoxal kinase2.7.1.350.446
2ejjSAHDiphthine synthase/0.446
2pchSAHDiphthine synthase/0.446
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.446
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.446
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.446
3bi5FADPolyamine oxidase FMS1/0.446
3nbvANPKetohexokinase/0.446
3qlrNDPDihydrofolate reductase1.5.1.30.446
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.446
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.446
4frkDWDBeta-secretase 13.4.23.460.446
4kba1QMCasein kinase I isoform delta2.7.11.10.446
4ki8ADP60 kDa chaperonin/0.446
4nbwNADShort-chain dehydrogenase/reductase SDR/0.446
4nh82LCHeat shock protein HSP 90-alpha/0.446
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.446
5hwsNAP2-dehydropantoate 2-reductase/0.446
6ctsCICCitrate synthase, mitochondrial2.3.3.10.446
1bdrIM1Gag-Pol polyprotein3.4.23.160.445
1ot7IU5Bile acid receptor/0.445
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.445
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.445
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.445
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.445
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.445
2c0cNAPProstaglandin reductase 310.445
2fj1CTCTetracycline repressor protein class D/0.445
2gtnLIEMitogen-activated protein kinase 14/0.445
2huxSAHDiphthine synthase/0.445
2xvv9DNSerum albumin/0.445
3cpsNADGlyceraldehyde-3-phosphate dehydrogenase/0.445
3o6o94MHeat shock protein 83/0.445
3qiyQI1Botulinum neurotoxin type A3.4.24.690.445
3sf6FDAGlutaryl-CoA dehydrogenase/0.445
3tneRITCandidapepsin-13.4.23.240.445
3w78CBDFMN-dependent NADH-azoreductase/0.445
4fuxE75Mitogen-activated protein kinase 12.7.11.240.445
4jbiNDPAlcohol dehydrogenase (Zinc)/0.445
4jkt04AGlutaminase kidney isoform, mitochondrial3.5.1.20.445
4jr3KJREpidermal growth factor receptor2.7.10.10.445
4m4922YL-lactate dehydrogenase A chain1.1.1.270.445
5dp2NAPCurF/0.445
1hosPHPGag-Pol polyprotein/0.444
1izhQ50Protease/0.444
2ignFADPyranose 2-oxidase/0.444
2iko7IGRenin3.4.23.150.444
2po7CHDFerrochelatase, mitochondrial4.99.1.10.444
2pwcG3GGag-Pol polyprotein3.4.23.160.444
2r5q1UNGag-Pol polyprotein/0.444
2xlpFADPutative flavin-containing monooxygenase/0.444
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.444
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.444
2z6rSAHDiphthine synthase/0.444
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.444
3hz5Z64Heat shock protein HSP 90-alpha/0.444
3ig6438Urokinase-type plasminogen activator3.4.21.730.444
3o96IQORAC-alpha serine/threonine-protein kinase2.7.11.10.444
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.444
3ogqAB1Pol polyprotein/0.444
3oriAGSSerine/threonine protein kinase/0.444
3p99LNPLanosterol 14-alpha-demethylase/0.444
3so9017Pol protein/0.444
3syiFADSulfide-quinone reductase/0.444
3uylTYDProbable NDP-rhamnosyltransferase/0.444
3v9v21LPeroxisome proliferator-activated receptor gamma/0.444
4b722FBBeta-secretase 13.4.23.460.444
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.444
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4nxvGDPMitochondrial dynamics protein MID51/0.444
4yswFADXanthine dehydrogenase/oxidase/0.444
5dpvSKEAurora kinase A2.7.11.10.444
1a8k0Q4Gag-Pol polyprotein3.4.23.160.443
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1fmjRTLRetinol dehydratase/0.443
1hiiC20Gag-Pol polyprotein/0.443
1pmn984Mitogen-activated protein kinase 102.7.11.240.443
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.443
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.443
1zz2B11Mitogen-activated protein kinase 14/0.443
2c12FADNitroalkane oxidase1.7.3.10.443
2igoFADPyranose 2-oxidase/0.443
2npaMMBPeroxisome proliferator-activated receptor alpha/0.443
2oapANPType II secretion system protein (GspE-2)/0.443
2qnqQN3Gag-Pol polyprotein3.4.23.160.443
2vv9IM9Cyclin-dependent kinase 22.7.11.220.443
2vwx7X4Ephrin type-B receptor 42.7.10.10.443
2wedPP6Penicillopepsin-13.4.23.200.443
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2xviFADPutative flavin-containing monooxygenase/0.443
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.443
3ekwDR7Gag-Pol polyprotein3.4.23.160.443
3gqvNAPEnoyl reductase LovC10.443
3icrFADCoenzyme A disulfide reductase/0.443
3lzs017Gag-Pol polyprotein3.4.23.160.443
3qu0X40Cyclin-dependent kinase 22.7.11.220.443
3s3r0IWCathepsin B-like peptidase (C01 family)/0.443
4a6nFADTetX family tetracycline inactivation enzyme/0.443
4btmF8ETau-tubulin kinase 12.7.11.10.443
4dgnLU2Casein kinase II subunit alpha2.7.11.10.443
4o0wADNAurora kinase A2.7.11.10.443
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4udrFAD5-(hydroxymethyl)furfural oxidase/0.443
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1dhrNADDihydropteridine reductase1.5.1.340.442
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
1qrpHH0Pepsin A-43.4.23.10.442
2d29FADAcyl-CoA dehydrogenase/0.442
2wxvWXVCyclin-dependent kinase 22.7.11.220.442
2zdt46CMitogen-activated protein kinase 102.7.11.240.442
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.442
3bg7FADPyranose 2-oxidase/0.442
3k5uPFQAurora kinase A2.7.11.10.442
3kfr3TLGag-Pol polyprotein/0.442
3lqfNADGalactitol dehydrogenase/0.442
3q43D66M1 family aminopeptidase3.4.110.442
3tjzGNPADP-ribosylation factor 1/0.442
3to6LYS_CMCHistone acetyltransferase ESA1/0.442
3toh079Gag-Pol polyprotein2.7.7.490.442
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.442
3wfjNAD2-dehydropantoate 2-reductase/0.442
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.442
4dplNAPMalonyl-CoA reductase1.2.1.750.442
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.442
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
4ly91YYGlucokinase regulatory protein/0.442
4mwhATPCasein kinase II subunit alpha2.7.11.10.442
4prvADPDNA gyrase subunit B/0.442
5a3bAPRSIR2 family protein/0.442
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.441
1dawANPCasein kinase II subunit alpha2.7.11.10.441
1di8DTQCyclin-dependent kinase 22.7.11.220.441
1ec3MS3Gag-Pol polyprotein3.4.23.160.441
1hb3SCVIsopenicillin N synthase1.21.3.10.441
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.441
1jgtAPCCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.441
1jolFFODihydrofolate reductase1.5.1.30.441
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.441
2b53D23Cyclin-dependent kinase 22.7.11.220.441
2bpv1INGag-Pol polyprotein3.4.23.160.441
2el3SAHDiphthine synthase/0.441
2ft9CHDFatty acid-binding protein 2, liver/0.441
2q29ACOOxalyl-CoA decarboxylase4.1.1.80.441
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
3at4CCKCasein kinase II subunit alpha2.7.11.10.441
3cifNADGlyceraldehyde-3-phosphate dehydrogenase/0.441
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3gobHXXDdmC/0.441
3ibqATPPyridoxal kinase/0.441
3ndtROCGag-Pol polyprotein3.4.23.160.441
3ocgOCGMitogen-activated protein kinase 14/0.441
3oibFDAPutative acyl-CoA dehydrogenase/0.441
3q44D50M1 family aminopeptidase3.4.110.441
3qizQI2Botulinum neurotoxin type A3.4.24.690.441
3tvuB37Acetyl-CoA carboxylase/0.441
3u9eCOALmo1369 protein/0.441
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.441
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.441
4btjATPTau-tubulin kinase 12.7.11.10.441
4c3yFAD3-ketosteroid dehydrogenase/0.441
4cdmFADDeoxyribodipyrimidine photolyase/0.441
4dqwATPInosine-5'-monophosphate dehydrogenase/0.441
4hvi19STyrosine-protein kinase JAK32.7.10.20.441
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.441
4i1iNADMalate dehydrogenase/0.441
4r20AERCytochrome P450 family 17 polypeptide 2/0.441
4yryFADGlutamate synthase, beta subunit/0.441
5irnADPNucleotide binding oligomerization domain containing 2/0.441
1h7wFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.440
1llqNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.440
1m0b0ZQGag-Pol polyprotein3.4.23.160.440
1msmJE2Gag-Pol polyprotein3.4.23.160.440
1mtrPI6Gag-Pol polyprotein3.4.23.160.440
1xe55FEPlasmepsin-23.4.23.390.440
2dwbANPAurora kinase A2.7.11.10.440
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.440
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.440
2jn3JN3Fatty acid-binding protein, liver/0.440
2nnpROCProtease/0.440
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.440
2vttLZDCyclin-dependent kinase 22.7.11.220.440
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.440
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
3a9wNADNDP-sugar epimerase/0.440
3bk2U5PRibonuclease J/0.440
3ggfGVDSerine/threonine-protein kinase 26/0.440
3gubGUBDeath-associated protein kinase 12.7.11.10.440
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.440
3pqbVGPPutative oxidoreductase/0.440
3t2yFADSulfide-quinone reductase/0.440
3t2zFADSulfide-quinone reductase/0.440
3t3c017Gag-Pol polyprotein3.4.23.160.440
3vt8YI3Vitamin D3 receptor/0.440
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.440
4k9dNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.440
4ocvANPAminoglycoside phosphotransferase/0.440
4oztP1AEcdysone receptor, putative/0.440
4q73FADBifunctional protein PutA/0.440
4ux9ANPMitogen-activated protein kinase 82.7.11.240.440