sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 1.000 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.592 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.500 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.499 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.498 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.498 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.496 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.496 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.493 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.493 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.490 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.487 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.485 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.485 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.485 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.484 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.484 | |
| 3zuy | TCH | Transporter | / | 0.484 | |
| 5a3c | NAD | SIR2 family protein | / | 0.484 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.483 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.483 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.483 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.483 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.483 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.482 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.482 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.482 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.482 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.481 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.481 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.480 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.480 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.479 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.479 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.478 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.477 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.477 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.477 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.477 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.477 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.476 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.476 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.476 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.475 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.475 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.475 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.475 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.475 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.474 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.474 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.474 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.474 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.474 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.472 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 4dja | FAD | (6-4) photolyase | / | 0.472 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.471 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.471 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.471 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.470 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.470 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.470 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.470 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.470 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.470 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.470 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.469 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.469 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.469 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.469 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.469 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.469 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.468 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.468 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.468 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.468 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.468 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.468 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.467 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.467 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.466 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 1r2j | FAD | FkbI | / | 0.466 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.466 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.466 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.466 | |
| 1c70 | L75 | Protease | / | 0.465 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.465 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.465 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.465 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.465 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.465 | |
| 4v12 | POG | MaoC like domain protein | / | 0.465 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.465 | |
| 2bxm | IMN | Serum albumin | / | 0.464 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.464 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.464 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.464 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.463 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.463 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.463 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.463 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.462 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.462 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.462 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.462 | |
| 4qec | NAP | ElxO | / | 0.462 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.461 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.461 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.461 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.461 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.461 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.461 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.461 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.461 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4l8u | 9AZ | Serum albumin | / | 0.461 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.461 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.460 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1gqt | ACP | Ribokinase | / | 0.460 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.460 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.460 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.460 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.460 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.460 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.460 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.460 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.459 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.459 | |
| 2y3r | TRK | TamL | / | 0.459 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.459 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.459 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.459 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.459 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.459 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.459 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.459 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.458 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.458 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.458 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.458 | |
| 3gob | HXX | DdmC | / | 0.458 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.458 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 3qai | XNN | Ketohexokinase | / | 0.458 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.458 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.457 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.457 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1kgj | FL8 | Transthyretin | / | 0.457 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.457 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.457 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.457 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.457 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.457 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.457 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.457 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.457 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.457 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.457 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.456 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.456 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.456 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.456 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.456 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.456 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.455 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.455 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.455 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.455 | |
| 3u9e | COA | Lmo1369 protein | / | 0.455 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.455 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.455 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.455 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.454 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.454 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.454 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.454 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.454 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.454 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.454 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.454 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.453 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.453 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.453 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.453 | |
| 3lu8 | IQX | Serum albumin | / | 0.453 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.453 | |
| 3umo | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.453 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.453 | |
| 3zux | TCH | Transporter | / | 0.453 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.453 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4ifc | ADP | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.453 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.453 | |
| 4n49 | MGT | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | 2.1.1.57 | 0.453 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.452 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.452 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.452 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.452 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.452 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.452 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.452 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4xwt | U5P | Ribonuclease J | / | 0.452 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.452 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.451 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.451 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.451 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.451 | |
| 3eej | 53R | Uncharacterized protein | / | 0.451 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.451 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.451 | |
| 1eio | GCH | Gastrotropin | / | 0.450 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 2y4g | TIR | TamL | / | 0.450 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta | / | 0.450 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta' | / | 0.450 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.450 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.450 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.450 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4j99 | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.450 | |
| 4u7w | NDP | MxaA | / | 0.450 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.449 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.449 | |
| 2bun | FAD | AppA protein | / | 0.449 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.449 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.449 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.449 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.449 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.449 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.449 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.449 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.449 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.449 | |
| 5a3b | APR | SIR2 family protein | / | 0.449 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.449 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.448 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.448 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1z95 | 198 | Androgen receptor | / | 0.448 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.448 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.448 | |
| 2y3s | TIR | TamL | / | 0.448 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3dag | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.448 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.448 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.448 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.448 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.448 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.447 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.447 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.447 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.447 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.447 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.447 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 3wec | AUI | Cytochrome P450 | / | 0.447 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.447 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.446 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.446 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.446 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.446 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.446 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.446 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.446 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.446 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.446 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.446 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.446 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.446 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.446 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.446 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.445 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.445 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.445 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.445 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.445 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.445 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.445 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.445 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.445 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.445 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.445 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.445 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.445 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.445 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.445 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1glf | ADP | Glycerol kinase | / | 0.444 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3cse | N22 | Uncharacterized protein | / | 0.444 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.444 | |
| 3fws | ANP | Transcriptional repressor CcpN | / | 0.444 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.444 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.444 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.444 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 3q92 | XNB | Ketohexokinase | / | 0.444 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.444 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4kwh | NAP | Reductase homolog | / | 0.444 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.444 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.444 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.443 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.443 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.443 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.443 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.443 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.443 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.443 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.443 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.443 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4l9k | EHF | Serum albumin | / | 0.443 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.443 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.443 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.443 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.442 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.442 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.442 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.442 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.442 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.442 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 4cdm | FAD | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 4f4p | 0SB | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.442 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.442 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.442 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.442 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.442 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.441 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.441 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.441 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.441 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.441 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.441 | |
| 3vth | APC | Carbamoyltransferase | / | 0.441 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.441 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.441 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.441 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.440 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.440 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.440 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.440 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.440 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.440 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.440 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.440 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.440 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3gqo | APR | Non-structural polyprotein | / | 0.440 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.440 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 4e2b | FMN | Dehydrogenase | / | 0.440 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.440 | |
| 4l4x | NDP | AmphI | / | 0.440 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.440 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.440 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4xr9 | NAD | CalS8 | / | 0.440 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.440 | |
| 4zs2 | FLU | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.440 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 |