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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/1.000
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.577
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.556
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.554
3bqr4RBDeath-associated protein kinase 3/0.542
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.534
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.529
2hog710Serine/threonine-protein kinase Chk12.7.11.10.525
3t8oATPRhodopsin kinase/0.519
4ysjADPCalmodulin-like domain protein kinase/0.518
1wvxBD4Death-associated protein kinase 12.7.11.10.517
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.517
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.515
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.514
3bu5ATPInsulin receptor2.7.10.10.513
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.512
2j0lANPFocal adhesion kinase 12.7.10.20.511
3c4xATPRhodopsin kinase/0.511
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.511
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.510
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.508
3q5iANPProtein kinase, putative/0.508
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.507
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.506
2j0m4STFocal adhesion kinase 12.7.10.20.505
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.505
4ic7ANPMitogen-activated protein kinase 72.7.11.240.505
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.505
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.504
3qc9ADPRhodopsin kinase/0.504
4ii5ADPCyclin-dependent kinase 22.7.11.220.504
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.503
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.503
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.502
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.501
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.501
3nux3NVCyclin-dependent kinase 62.7.11.220.501
4nks2M2Fibroblast growth factor receptor 1/0.501
5av2KMPDeath-associated protein kinase 12.7.11.10.500
5av3KMPDeath-associated protein kinase 12.7.11.10.500
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.499
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.498
4nka2K7Fibroblast growth factor receptor 1/0.498
2c6eHPMAurora kinase A2.7.11.10.497
2izsBRQCasein kinase I isoform gamma-32.7.11.10.497
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.497
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.496
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.496
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.496
3zxtACPDeath-associated protein kinase 12.7.11.10.496
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
2vu3LZECyclin-dependent kinase 22.7.11.220.495
4bcmT7ZCyclin-dependent kinase 22.7.11.220.495
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.495
1finATPCyclin-dependent kinase 22.7.11.220.494
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.494
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.494
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.494
4qnyANPMitogen activated protein kinase, putative/0.494
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.493
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.493
4i3zADPCyclin-dependent kinase 22.7.11.220.492
4qmlANPSerine/threonine-protein kinase 242.7.11.10.492
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
3bhy7CPDeath-associated protein kinase 3/0.491
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.491
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
4anqVGHALK tyrosine kinase receptor2.7.10.10.490
4b8lA0PAurora kinase B-A2.7.11.10.490
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.489
2pywADPMethylthioribose kinase2.7.1.1000.489
3c4wATPRhodopsin kinase/0.489
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.489
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.489
5eg3ACPFibroblast growth factor receptor 2/0.489
3a7hATPSerine/threonine-protein kinase 242.7.11.10.488
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.488
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.487
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.487
2xp2VGHALK tyrosine kinase receptor2.7.10.10.487
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.487
4l9i8PRRhodopsin kinase/0.487
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.486
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.486
2v7a627Tyrosine-protein kinase ABL12.7.10.20.486
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.486
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.486
5auwQUEDeath-associated protein kinase 12.7.11.10.486
4iebANPCalmodulin-domain protein kinase 1/0.485
4xlvACPInsulin receptor2.7.10.10.485
2pulACPMethylthioribose kinase2.7.1.1000.484
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.484
3igoANPCalmodulin-domain protein kinase 1, putative/0.484
4ansVGHALK tyrosine kinase receptor2.7.10.10.484
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.484
4j95ACPFibroblast growth factor receptor 2/0.484
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.483
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.483
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.482
4gt3ATPMitogen-activated protein kinase 12.7.11.240.482
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.481
2wqeADPAurora kinase A2.7.11.10.481
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.481
5dosATPAurora kinase A2.7.11.10.481
1pkdUCNCyclin-dependent kinase 22.7.11.220.480
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.480
4aguD15Cyclin-dependent kinase-like 1/0.480
4b0gVEKAurora kinase A2.7.11.10.480
4btjADPTau-tubulin kinase 12.7.11.10.480
4c3pACPAurora kinase A2.7.11.10.480
4cd0AWJALK tyrosine kinase receptor2.7.10.10.480
4fx360KCyclin-dependent kinase 22.7.11.220.480
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.479
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.479
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.479
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.479
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.479
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.479
2j7t274Serine/threonine-protein kinase 102.7.11.10.478
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.478
3js2VM1Fibroblast growth factor receptor 1/0.478
3sheI85MAP kinase-activated protein kinase 32.7.11.10.478
4btjATPTau-tubulin kinase 12.7.11.10.478
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.477
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.477
4riyADPEpidermal growth factor receptor2.7.10.10.477
1qmzATPCyclin-dependent kinase 22.7.11.220.476
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.476
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.476
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
4bbe3O4Tyrosine-protein kinase JAK2/0.476
4j99ACPFibroblast growth factor receptor 2/0.476
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.476
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.476
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.475
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.475
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.475
4wkqIREEpidermal growth factor receptor2.7.10.10.475
5l8lADPAurora kinase A2.7.11.10.475
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.474
2c5nCK8Cyclin-dependent kinase 22.7.11.220.474
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.474
3t2kFADSulfide-quinone reductase/0.474
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.474
4fv9E71Mitogen-activated protein kinase 12.7.11.240.474
2etm7PYFocal adhesion kinase 12.7.10.20.473
3i60E86Mitogen-activated protein kinase 12.7.11.240.473
3t14FADSulfide-quinone reductase/0.473
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.473
5aacVGHALK tyrosine kinase receptor2.7.10.10.473
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.472
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.472
3at4CCKCasein kinase II subunit alpha2.7.11.10.472
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.472
4fv8E63Mitogen-activated protein kinase 12.7.11.240.472
5aaaVGHALK tyrosine kinase receptor2.7.10.10.472
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.471
1fvv107Cyclin-dependent kinase 22.7.11.220.471
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.471
1zrzBI1Protein kinase C iota type2.7.11.130.471
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.471
3q92XNBKetohexokinase/0.471
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.471
4gmy0X5Tyrosine-protein kinase JAK2/0.471
4izy1J2Mitogen-activated protein kinase 82.7.11.240.471
4k33ACPFibroblast growth factor receptor 32.7.10.10.471
2bmcMPYAurora kinase A2.7.11.10.470
2izrBRKCasein kinase I isoform gamma-32.7.11.10.470
2w4jADPDeath-associated protein kinase 12.7.11.10.470
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.470
3gubGUBDeath-associated protein kinase 12.7.11.10.470
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.470
4hyu1BKMitogen-activated protein kinase 82.7.11.240.470
1ee0CAA2-pyrone synthase/0.469
1jklANPDeath-associated protein kinase 12.7.11.10.469
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.469
3a62STURibosomal protein S6 kinase beta-12.7.11.10.469
3s2pPMUCyclin-dependent kinase 22.7.11.220.469
4b7sQLECytochrome P450 monooxygenase PikC/0.469
4eooATPCyclin-dependent kinase 22.7.11.220.469
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.469
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.469
4qo9627Serine/threonine-protein kinase 242.7.11.10.469
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.468
2itnANPEpidermal growth factor receptor2.7.10.10.468
2py3ACPFibroblast growth factor receptor 2/0.468
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.468
3plsANPMacrophage-stimulating protein receptor2.7.10.10.468
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.468
4grb0XGCasein kinase II subunit alpha2.7.11.10.468
1cm8ANPMitogen-activated protein kinase 12/0.467
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.467
4hvh19RTyrosine-protein kinase JAK32.7.10.20.466
4hvi19STyrosine-protein kinase JAK32.7.10.20.466
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.466
2fgiPD1Fibroblast growth factor receptor 1/0.465
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.465
3lltANPProtein serine/threonine kinase-1/0.465
3my5RFZCyclin-dependent kinase 22.7.11.220.465
3nup3NUCyclin-dependent kinase 62.7.11.220.465
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.465
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.465
4fuxE75Mitogen-activated protein kinase 12.7.11.240.465
2fvdLIACyclin-dependent kinase 22.7.11.220.464
2uzbC75Cyclin-dependent kinase 22.7.11.220.464
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.464
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.464
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.464
3qx2X63Cyclin-dependent kinase 22.7.11.220.464
3tnwF18Cyclin-dependent kinase 22.7.11.220.464
3zewSTUEphrin type-B receptor 42.7.10.10.464
4jbpYPHAurora kinase A2.7.11.10.464
5ap57RODual specificity protein kinase TTK2.7.12.10.464
5awmANPStress-activated protein kinase JNK2.7.11.240.464
5cvfATPCasein kinase II subunit alpha2.7.11.10.464
5g3sFDAFlavin-dependent L-tryptophan oxidase VioA/0.464
2c4g514Cyclin-dependent kinase 22.7.11.220.463
2henADPEphrin type-B receptor 22.7.10.10.463
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.463
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.463
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.463
4c4h7RODual specificity protein kinase TTK2.7.12.10.463
4f630S7Fibroblast growth factor receptor 1/0.463
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.463
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.463
4j97ACPFibroblast growth factor receptor 2/0.463
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.462
1xjdSTUProtein kinase C theta type2.7.11.130.462
2j0j4STFocal adhesion kinase 12.7.10.20.462
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.462
3c4zADPRhodopsin kinase/0.462
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.462
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.462
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.462
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.462
1jkkANPDeath-associated protein kinase 12.7.11.10.461
2x6dX6DAurora kinase A2.7.11.10.461
3d7tSTUTyrosine-protein kinase CSK/0.461
3qaiXNNKetohexokinase/0.461
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.461
4g170VNCasein kinase I isoform gamma-32.7.11.10.461
4wboANWRhodopsin kinase/0.461
1yvj4STTyrosine-protein kinase JAK32.7.10.20.460
2itqITQEpidermal growth factor receptor2.7.10.10.460
4d58BI9Focal adhesion kinase 12.7.10.20.460
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.460
2ckeIQUDeath-associated protein kinase 2/0.459
2pz5ACPFibroblast growth factor receptor 2/0.459
2y03Y01Beta-1 adrenergic receptor/0.459
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.459
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.459
3q9xEMOCasein kinase II subunit alpha2.7.11.10.459
4ez50RSCyclin-dependent kinase 62.7.11.220.459
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.459
5aabVGHALK tyrosine kinase receptor2.7.10.10.459
2vrx447Aurora kinase B-A2.7.11.10.458
2w17I19Cyclin-dependent kinase 22.7.11.220.458
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.458
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.458
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.458
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.458
3qxpX64Cyclin-dependent kinase 22.7.11.220.458
3tvuB37Acetyl-CoA carboxylase/0.458
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.458
4c57FEFCyclin-G-associated kinase2.7.11.10.458
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.458
4jboWPHAurora kinase A2.7.11.10.458
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.458
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.457
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.457
3flsFLSMitogen-activated protein kinase 14/0.457
4eol1ROCyclin-dependent kinase 22.7.11.220.457
4eym0RXMitogen-activated protein kinase 132.7.11.240.457
4f640S8Fibroblast growth factor receptor 1/0.457
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
1aq1STUCyclin-dependent kinase 22.7.11.220.456
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.456
1zyjBI5Mitogen-activated protein kinase 14/0.456
2pzpACPFibroblast growth factor receptor 2/0.456
2vv9IM9Cyclin-dependent kinase 22.7.11.220.456
2yaaATPDeath-associated protein kinase 2/0.456
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.456
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.456
3gu7ADPDeath-associated protein kinase 12.7.11.10.456
3h0sB38Acetyl-CoA carboxylase/0.456
3tucFPWTyrosine-protein kinase SYK2.7.10.20.456
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.456
4aotGW8Serine/threonine-protein kinase 102.7.11.10.456
4hgt15GCasein kinase I isoform delta2.7.11.10.456
1y0s331Peroxisome proliferator-activated receptor delta/0.455
2ittAEEEpidermal growth factor receptor2.7.10.10.455
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.455
2qoqANPEphrin type-A receptor 32.7.10.10.455
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.455
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.455
3nga3NGCasein kinase II subunit alpha2.7.11.10.455
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1u54ACPActivated CDC42 kinase 1/0.454
2ghmLICMitogen-activated protein kinase 14/0.454
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.454
3eigMTXDihydrofolate reductase1.5.1.30.454
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.454
4b7dQLECytochrome P450 monooxygenase PikC/0.454
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.454
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.454
1ouy094Mitogen-activated protein kinase 14/0.453
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.453
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.453
2vzmNRBCytochrome P450 monooxygenase PikC/0.453
2xb7GUIALK tyrosine kinase receptor2.7.10.10.453
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.453
3s4qNK0Mitogen-activated protein kinase 14/0.453
3uvqFS8Mitogen-activated protein kinase 14/0.453
3wowANPCasein kinase II subunit alpha2.7.11.10.453
3ztxZTXAurora kinase B-A2.7.11.10.453
4jia1K3Tyrosine-protein kinase JAK2/0.453
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.453
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1i44ACPInsulin receptor2.7.10.10.452
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.452
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.452
2j9mPY8Cyclin-dependent kinase 22.7.11.220.452
3nynSGVG protein-coupled receptor kinase 62.7.11.160.452
3orpAGSSerine/threonine protein kinase/0.452
3rak03ZCyclin-dependent kinase 22.7.11.220.452
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.452
4c4g7RODual specificity protein kinase TTK2.7.12.10.452
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.452
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.452
4jrnANPRhoptry kinase family protein/0.452
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.452
4o0wADNAurora kinase A2.7.11.10.452
1ig1ANPDeath-associated protein kinase 12.7.11.10.451
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.451
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.451
2h96893Mitogen-activated protein kinase 82.7.11.240.451
2ijmADPFocal adhesion kinase 12.7.10.20.451
3hx4ANPCalmodulin-domain protein kinase 1/0.451
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.451
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.451
4o0uADNAurora kinase A2.7.11.10.451
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.451
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4wloNAIMalate dehydrogenase, mitochondrial1.1.1.370.451
1k6cMK1Gag-Pol polyprotein3.4.23.160.450
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.450
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.450
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.450
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.450
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.450
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.450
3ekp478Gag-Pol polyprotein3.4.23.160.450
3gu6ADPDeath-associated protein kinase 12.7.11.10.450
3hwrNDP2-dehydropantoate 2-reductase/0.450
3r9nZ68Cyclin-dependent kinase 22.7.11.220.450
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.450
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4fv6E57Mitogen-activated protein kinase 12.7.11.240.450
5cu6ATPCasein kinase II subunit alpha2.7.11.10.450
1bwb146Gag-Pol polyprotein3.4.23.160.449
1h0w207Cyclin-dependent kinase 22.7.11.220.449
1pxpCK8Cyclin-dependent kinase 22.7.11.220.449
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
2f2cAP9Cyclin-dependent kinase 62.7.11.220.449
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.449
3cifNADGlyceraldehyde-3-phosphate dehydrogenase/0.449
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.449
3gc9B45Mitogen-activated protein kinase 112.7.11.240.449
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.449
3qyw6PBMitogen-activated protein kinase 12.7.11.240.449
3umw596Serine/threonine-protein kinase pim-12.7.11.10.449
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.449
4b99R4LMitogen-activated protein kinase 72.7.11.240.449
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.449
4wluNADMalate dehydrogenase, mitochondrial1.1.1.370.449
5ap7SVEDual specificity protein kinase TTK2.7.12.10.449
1pmn984Mitogen-activated protein kinase 102.7.11.240.448
2excJNKMitogen-activated protein kinase 102.7.11.240.448
2ijmATPFocal adhesion kinase 12.7.10.20.448
3cgfJNFMitogen-activated protein kinase 102.7.11.240.448
3gc8B45Mitogen-activated protein kinase 112.7.11.240.448
3rk708ZCyclin-dependent kinase 22.7.11.220.448
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.448
4deeADPAurora kinase A2.7.11.10.448
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.448
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.448
4gk2L66Ephrin type-A receptor 32.7.10.10.448
4i22IREEpidermal growth factor receptor2.7.10.10.448
4n57ADPAPH(2'')-Id/0.448
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.448
1rkxNADCDP-D-glucose-4,6-dehydratase/0.447
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.447
2eb3ANPEpidermal growth factor receptor2.7.10.10.447
2pwlACPFibroblast growth factor receptor 2/0.447
2qhcAB1Protease/0.447
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.447
2zmd537Dual specificity protein kinase TTK2.7.12.10.447
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.447
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3lctADPALK tyrosine kinase receptor2.7.10.10.447
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3ogqAB1Pol polyprotein/0.447
3ormAGSSerine/threonine protein kinase/0.447
3rk507ZCyclin-dependent kinase 22.7.11.220.447
3rkb12ZCyclin-dependent kinase 22.7.11.220.447
3vjoANPEpidermal growth factor receptor2.7.10.10.447
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.447
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.447
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.447
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.447
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4j98ACPFibroblast growth factor receptor 2/0.447
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.447
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.447
5br4NADLactaldehyde reductase1.1.1.770.447
5dnrATPAurora kinase A2.7.11.10.447
5g3tFDAFlavin-dependent L-tryptophan oxidase VioA/0.447
1mq4ADPAurora kinase A2.7.11.10.446
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.446
2qd7065Gag-Pol polyprotein3.4.23.160.446
2uxzHI1Gag-Pol polyprotein3.4.23.160.446
2xclANPPhosphoribosylamine--glycine ligase/0.446
2yfxVGHALK tyrosine kinase receptor2.7.10.10.446
3bheBZNGag-Pol polyprotein3.4.23.160.446
3cgoJNOMitogen-activated protein kinase 102.7.11.240.446
3dhoB2MStreptogramin A acetyltransferase2.3.10.446
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.446
3rm719ZCyclin-dependent kinase 22.7.11.220.446
3uvp048Mitogen-activated protein kinase 14/0.446
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.446
4d4sBI9Focal adhesion kinase 12.7.10.20.446
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.446
4hge15VTyrosine-protein kinase JAK2/0.446
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.446
5auvAGIDeath-associated protein kinase 12.7.11.10.446
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1fvt106Cyclin-dependent kinase 22.7.11.220.445
1ie4T44Transthyretin/0.445
1k6tXN1Gag-Pol polyprotein3.4.23.160.445
1qbt146Gag-Pol polyprotein3.4.23.160.445
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2p5uNADUDP-glucose 4-epimerase/0.445
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.445
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.445
2zjwREFCasein kinase II subunit alpha2.7.11.10.445
3nu3478Gag-Pol polyprotein3.4.23.160.445
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3r71X86Cyclin-dependent kinase 22.7.11.220.445
4c62XWWTyrosine-protein kinase JAK2/0.445
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.445
4fnyI3KALK tyrosine kinase receptor2.7.10.10.445
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.445
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1gy3ATPCyclin-dependent kinase 22.7.11.220.444
1ivq0PXGag-Pol polyprotein/0.444
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.444
1v9aSAHUncharacterized protein/0.444
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.444
2vgoAD5Aurora kinase B-A2.7.11.10.444
2y02Y01Beta-1 adrenergic receptor/0.444
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.444
3ggfGVDSerine/threonine-protein kinase 26/0.444
3sz0FADSulfide-quinone reductase/0.444
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.444
3wd7COAAcridone synthase/0.444
4fyn0VETyrosine-protein kinase SYK2.7.10.20.444
4fz60VGTyrosine-protein kinase SYK2.7.10.20.444
4gk3L87Ephrin type-A receptor 32.7.10.10.444
4hdbG52Gag-Pol polyprotein3.4.23.160.444
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.444
1db1VDXVitamin D3 receptor/0.443
1gii1PUCyclin-dependent kinase 22.7.11.220.443
1ohr1UNV-1 PROTEASE protein/0.443
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2aidTHKGag-Pol polyprotein3.4.23.160.443
2avvMK1Gag-Pol polyprotein3.4.23.160.443
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.443
2csnCKICasein kinase I homolog 12.7.11.10.443
2i0aMUIProtease/0.443
2qo9ANPEphrin type-A receptor 32.7.10.10.443
2r3wG3GGag-Pol polyprotein3.4.23.160.443
2vtsLZCCyclin-dependent kinase 22.7.11.220.443
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.443
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.443
3ctj320Hepatocyte growth factor receptor2.7.10.10.443
3nwxKVSGag-Pol polyprotein3.4.23.160.443
3rvg17PTyrosine-protein kinase JAK2/0.443
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ccbOFGALK tyrosine kinase receptor2.7.10.10.443
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.443
4gk4L90Ephrin type-A receptor 32.7.10.10.443
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.443
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1rrmAPRLactaldehyde reductase1.1.1.770.442
1w2xRCPAcetyl-CoA carboxylase/0.442
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.442
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.442
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3em6017Gag-Pol polyprotein3.4.23.160.442
3nwyGTPUridylate kinase/0.442
3ortAGSSerine/threonine protein kinase/0.442
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.442
4bcqTJFCyclin-dependent kinase 22.7.11.220.442
4fk1FADPutative thioredoxin reductase/0.442
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.442
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.442
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.442
4nifANPMitogen-activated protein kinase 12.7.11.240.442
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.442
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
1z1hHBBGag-Pol polyprotein3.4.23.160.441
2bpy3INGag-Pol polyprotein3.4.23.160.441
2c7xNRBCytochrome P450 monooxygenase PikC/0.441
2cjmATPCyclin-dependent kinase 22.7.11.220.441
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.441
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.441
2qo7ANPEphrin type-A receptor 32.7.10.10.441
2wleCOAPolysialic acid O-acetyltransferase/0.441
2wpa889Cyclin-dependent kinase 22.7.11.220.441
2y00Y01Beta-1 adrenergic receptor/0.441
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3opdHIEHeat shock protein 83/0.441
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.441
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.441
4bbfO19Tyrosine-protein kinase JAK2/0.441
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4cy8FDA2-hydroxybiphenyl-3-monooxygenase/0.441
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.441
4hgs15GCasein kinase I isoform gamma-32.7.11.10.441
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.441
4tuvCPZCytochrome P450 1191.140.441
4x4jFADPutative oxygenase/0.441
1b6kPI5Gag-Pol polyprotein3.4.23.160.440
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.440
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.440
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.440
3l8p0CEAngiopoietin-1 receptor2.7.10.10.440
3nwq2NCGag-Pol polyprotein3.4.23.160.440
3r7iX9ICyclin-dependent kinase 22.7.11.220.440
3ttjJBIMitogen-activated protein kinase 102.7.11.240.440
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.440
4c4f7CEDual specificity protein kinase TTK2.7.12.10.440
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.440