sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 1.000 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.653 | |
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.617 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.607 | |
| 3dp9 | BIG | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.603 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.600 | |
| 4wkb | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.584 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.580 | |
| 4bmz | MTA | Aminodeoxyfutalosine nucleosidase | / | 0.563 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.515 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.512 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.511 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.506 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.503 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.502 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.499 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.497 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.496 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.495 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.492 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.492 | |
| 3e6y | CW1 | 14-3-3-like protein C | / | 0.491 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.489 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.488 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.488 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.487 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.487 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.485 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 3hll | I46 | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.483 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.481 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.481 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.480 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.480 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.479 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.479 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.478 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.477 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.477 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.476 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.476 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.476 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.476 | |
| 4rtr | SAM | DNA adenine methylase | 2.1.1.72 | 0.476 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 3tdk | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.475 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.474 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.473 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.473 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.473 | |
| 1srf | MTB | Streptavidin | / | 0.472 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.472 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.472 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.472 | |
| 1syn | F89 | Thymidylate synthase | / | 0.471 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.471 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.471 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.471 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 1mbz | IOT | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.470 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.470 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.470 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.470 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.469 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.469 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.469 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.469 | |
| 4y0k | NAP | AntE | / | 0.469 | |
| 4zth | GG5 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.469 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.468 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.468 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.468 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.468 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.468 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.468 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.468 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.468 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.468 | |
| 1kek | HTL | Pyruvate synthase | / | 0.467 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.467 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.467 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.467 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.467 | |
| 4hdr | DMD | ArsB | / | 0.467 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.467 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.466 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.466 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.466 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.466 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.466 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.465 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.465 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.465 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.465 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.465 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.464 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.464 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.464 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.464 | |
| 3ndj | JHZ | Methyltransferase | / | 0.464 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.464 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.463 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.463 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.463 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.463 | |
| 2pda | TPP | Pyruvate synthase | / | 0.463 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.463 | |
| 4n1g | CEI | Obelin | / | 0.463 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.462 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.462 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.462 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4iae | 1DX | Alr2278 protein | / | 0.462 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.461 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.461 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.461 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.461 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.461 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.460 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.460 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.460 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.460 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.460 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.460 | |
| 1prc | UQ1 | Reaction center protein L chain | / | 0.459 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.459 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2hzq | STR | Apolipoprotein D | / | 0.459 | |
| 3mcy | ZH1 | FimH | / | 0.459 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.459 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.459 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.459 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.459 | |
| 4eh5 | IRG | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.459 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.459 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.459 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.459 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.458 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.458 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.458 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.458 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.458 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.458 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.457 | |
| 1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.457 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.457 | |
| 1n2v | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.457 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.457 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.457 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.457 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.457 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.456 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.456 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.456 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.456 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.456 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.456 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.456 | |
| 1ia9 | ANP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.455 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.455 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.455 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.455 | |
| 2bxo | OPB | Serum albumin | / | 0.455 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
| 3rix | 923 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.455 | |
| 3up3 | XCA | aceDAF-12 | / | 0.455 | |
| 3uq9 | TBN | Putative adenosine kinase | / | 0.455 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4eh3 | IRG | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4y1b | NAP | AntE | / | 0.455 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.454 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.454 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.454 | |
| 3bgv | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.454 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.454 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 3ua1 | 08Y | Cytochrome P450 3A4 | / | 0.454 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.454 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.454 | |
| 1eqb | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.453 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.453 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.453 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.453 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.453 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.453 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.453 | |
| 3ar6 | 12D | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 3arv | SAU | Chitinase A | / | 0.453 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 4eh4 | IRG | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.453 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.453 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.453 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.453 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.452 | |
| 1sui | FRE | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.452 | |
| 2bxn | IDB | Serum albumin | / | 0.452 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.452 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.452 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.452 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2z1w | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.452 | |
| 3n1t | 5GP | Purine nucleoside phosphoramidase | / | 0.452 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.452 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.452 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.451 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.451 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1jje | BYS | Beta-lactamase | / | 0.451 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.451 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.451 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.451 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.451 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.451 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.451 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.451 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.451 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.451 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.451 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.450 | |
| 1p16 | GTP | mRNA-capping enzyme subunit alpha | 2.7.7.50 | 0.450 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.450 | |
| 4fps | 0UX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.450 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.450 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.449 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.449 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.449 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.449 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.449 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.449 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4blw | SAH | Ribosomal RNA large subunit methyltransferase J | / | 0.449 | |
| 4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.449 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.449 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.448 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.448 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.448 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2wuu | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.448 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 3ge7 | AFQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.448 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.448 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4edf | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.448 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
| 4k4f | K4F | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4o7u | THF | Thymidylate synthase | / | 0.448 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.448 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.448 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.448 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.447 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 1z9a | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.447 | |
| 2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.447 | |
| 2yis | I46 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.447 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.447 | |
| 4e2y | JHZ | Methyltransferase | / | 0.447 | |
| 4gg9 | 0WW | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.447 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.447 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.447 | |
| 4rtm | SAM | DNA adenine methylase | 2.1.1.72 | 0.447 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.446 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1qv0 | CZH | Obelin | / | 0.446 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1zp4 | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.446 | |
| 2op0 | 7PC | Enoyl-ACP reductase | / | 0.446 | |
| 2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 | 0.446 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2r8p | T6F | Transketolase 1 | / | 0.446 | |
| 2rtq | IMI | Streptavidin | / | 0.446 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.446 | |
| 3k3i | I46 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.446 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 3wzn | BTN | Streptavidin | / | 0.446 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.446 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.446 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.446 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.446 | |
| 4phl | PIL | Phosphodiesterase | / | 0.446 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.445 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.445 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.445 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.445 | |
| 2q3e | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.445 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 2y3f | BTN | Streptavidin | / | 0.445 | |
| 2y3r | TRK | TamL | / | 0.445 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.445 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.445 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.445 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.445 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.445 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.445 | |
| 4rto | SFG | DNA adenine methylase | 2.1.1.72 | 0.445 | |
| 4rts | SAM | DNA adenine methylase | 2.1.1.72 | 0.445 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.445 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.445 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.444 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.444 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.444 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.444 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3uq6 | ADN | Putative adenosine kinase | / | 0.444 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.444 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.444 | |
| 4h80 | 04T | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.444 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.444 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.443 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.443 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.443 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.443 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.443 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.443 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.443 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2yat | EEU | Estrogen receptor | / | 0.443 | |
| 2zsc | BTN | Tamavidin2 | / | 0.443 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.443 | |
| 3gan | SVR | Protein RDM1 | / | 0.443 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.443 | |
| 3hl7 | I46 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.443 | |
| 3pfh | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.443 | |
| 3up0 | D7S | aceDAF-12 | / | 0.443 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.443 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.443 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4rtn | SAH | DNA adenine methylase | 2.1.1.72 | 0.443 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.443 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.442 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.442 | |
| 1swt | BTN | Streptavidin | / | 0.442 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2obf | F83 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.442 | |
| 2r2g | EMF | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2uza | HTL | Pyruvate synthase | / | 0.442 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.442 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.442 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.442 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.442 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.442 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.442 | |
| 3v97 | SAH | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.442 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.442 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.442 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.442 | |
| 4la0 | 198 | Serum albumin | / | 0.442 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 1axw | MTX | Thymidylate synthase | / | 0.441 | |
| 1b48 | HAG | Glutathione S-transferase A4 | 2.5.1.18 | 0.441 | |
| 1dxr | MST | Reaction center protein L chain | / | 0.441 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.441 | |
| 1h5r | THM | Glucose-1-phosphate thymidylyltransferase 1 | / | 0.441 | |
| 1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.441 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.441 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.441 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.441 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 3htj | ET | EbrA repressor | / | 0.441 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3lu8 | IQX | Serum albumin | / | 0.441 | |
| 3p9t | TCL | Repressor | / | 0.441 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.441 | |
| 4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.441 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.441 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.440 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.440 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1y5w | NEZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.440 | |
| 1yrs | ADP | Kinesin-like protein KIF11 | / | 0.440 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.440 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.440 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.440 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.440 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.440 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.440 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4e2x | TYD | Methyltransferase | / | 0.440 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4lv8 | ADP | Rhoptry protein 5 C | / | 0.440 | |
| 4q8p | CKR | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 4rtp | SAM | DNA adenine methylase | 2.1.1.72 | 0.440 | |
| 4xug | F9F | Tryptophan synthase alpha chain | / | 0.440 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.440 |