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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/1.000
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.648
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.623
3tjzGNPADP-ribosylation factor 1/0.523
3q43D66M1 family aminopeptidase3.4.110.522
4df2FMNNADPH dehydrogenase/0.503
3d91REMRenin3.4.23.150.500
2g247IGRenin3.4.23.150.498
2g1s4IGRenin3.4.23.150.497
1xe55FEPlasmepsin-23.4.23.390.496
3d3xARG_ILE_MET_GLU_NH2Type E botulinum toxin/0.491
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.488
3tr05GPGuanylate kinase/0.487
2il2LIXRenin3.4.23.150.486
2b53D23Cyclin-dependent kinase 22.7.11.220.484
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.484
4g7gVFVLanosterol 14-alpha-demethylase/0.484
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.484
2bf4FADNADPH--cytochrome P450 reductase/0.483
2rlcCHDCholoylglycine hydrolase3.5.1.240.483
3hyoADPPyridoxal kinase/0.483
4de2DN3Beta-lactamase/0.483
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.482
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.482
3lpkZ76Beta-secretase 13.4.23.460.481
1gcoNADGlucose 1-dehydrogenase1.1.1.470.480
1lbcCYZGlutamate receptor 2/0.480
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4a6rTA8Probable aminotransferase/0.480
4d89BXDBeta-secretase 13.4.23.460.480
2ifaFMNUncharacterized protein/0.479
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.479
3lqfNADGalactitol dehydrogenase/0.479
1x1aSAMC-20 methyltransferase/0.478
2oapANPType II secretion system protein (GspE-2)/0.478
2yxuATPPyridoxal kinase2.7.1.350.478
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.478
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.478
1me6IVSPlasmepsin-23.4.23.390.477
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.477
1psa0ZLPepsin A3.4.23.10.476
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.476
4dptAGSMevalonate diphosphate decarboxylase/0.476
4eb5PLPCysteine desulfurase IscS 2/0.476
4eb7PLPCysteine desulfurase IscS 2/0.476
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.475
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.475
2dftADPShikimate kinase2.7.1.710.474
3rpeFADPutative modulator of drug activity/0.474
3w8eNAD3-hydroxybutyrate dehydrogenase/0.474
3wqmB29Diterpene synthase3.1.7.80.474
4g3jVNTLanosterol 14-alpha-demethylase/0.474
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.473
3gqvNAPEnoyl reductase LovC10.473
3c3eGDP2-phospho-L-lactate transferase/0.472
3k5c0BIBeta-secretase 13.4.23.460.472
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.472
3wagTYDGlycosyltransferase/0.472
2xx91NFGlutamate receptor 2/0.471
3qt62P0Mevalonate diphosphate decarboxylase/0.471
4m83ERYOleandomycin glycosyltransferase2.4.10.471
1g1aNADdTDP-glucose 4,6-dehydratase/0.470
2ikuLIYRenin3.4.23.150.470
3f03FMNPentaerythritol tetranitrate reductase/0.470
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.470
1f8fNADBenzyl alcohol dehydrogenase/0.469
1kp3ATPArgininosuccinate synthase6.3.4.50.469
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
3cic316Beta-secretase 13.4.23.460.469
1rneC60Renin3.4.23.150.468
2fy4COACholine O-acetyltransferase2.3.1.60.468
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.468
2zr9DTPProtein RecA/0.468
2zvbSAHPrecorrin-3 C17-methyltransferase/0.468
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.468
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.468
3fhyATPPyridoxal kinase2.7.1.350.468
5dldUD1UDP-N-Acetylglucosamine 2-epimerase/0.468
1ex75GPGuanylate kinase2.7.4.80.467
2g226IGRenin3.4.23.150.467
2xukTZ5Acetylcholinesterase3.1.1.70.467
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.467
3ohh3HHBeta-secretase 13.4.23.460.467
3q44D50M1 family aminopeptidase3.4.110.467
4c4oNADSADH/0.467
4de00JBBeta-lactamase/0.467
4jtqNAPAldo-keto reductase family 1 member C2/0.467
4lxk1YTBeta-secretase 13.4.23.460.467
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.466
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.466
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.466
2p83MR0Beta-secretase 13.4.23.460.466
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.466
3v2uATPProtein GAL3/0.466
4du82P0Mevalonate diphosphate decarboxylase/0.466
1j49NADD-lactate dehydrogenase1.1.1.280.465
1rp0AHZThiamine thiazole synthase, chloroplastic/0.465
1udaUFGUDP-glucose 4-epimerase5.1.3.20.465
1w34FADFerredoxin--NADP reductase1.18.1.20.465
1xe65FPPlasmepsin-23.4.23.390.465
2anb5GPGuanylate kinase2.7.4.80.465
4ipw1G7Mycocyclosin synthase1.14.21.90.465
4lutDCSAlanine racemase/0.465
1bwsNDPGDP-L-fucose synthase/0.464
1h74ADPHomoserine kinase2.7.1.390.464
2a94AP0L-lactate dehydrogenase1.1.1.270.464
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.464
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.464
4mo2FADUDP-galactopyranose mutase/0.464
5ftfADPTPR domain protein/0.464
1qrpHH0Pepsin A-43.4.23.10.463
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.463
4ambDUDPutative glycosyl transferase/0.463
4j4nD44Peptidylprolyl isomerase/0.463
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.463
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.462
2cv2GSUGlutamate--tRNA ligase6.1.1.170.462
4a81DXCMajor pollen allergen Bet v 1-A/0.462
4a83DXCMajor pollen allergen Bet v 1-A/0.462
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.462
4opuFDAConserved Archaeal protein/0.462
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.462
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.461
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.461
1v0jFADUDP-galactopyranose mutase5.4.99.90.461
1vbiNADMalate/L-lactate dehydrogenase family protein/0.461
2vyqFADFerredoxin--NADP reductase1.18.1.20.461
3gw9VNILanosterol 14-alpha-demethylase/0.461
3nutSAHPrecorrin-3 methylase/0.461
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.461
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.461
1bil0IURenin3.4.23.150.460
1geeNADGlucose 1-dehydrogenase1.1.1.470.460
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.460
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.460
2gv8NDPThiol-specific monooxygenase1.14.130.460
3djjFADGlutathione reductase, mitochondrial1.8.1.70.460
3enkUPGUDP-glucose 4-epimerase/0.460
1f8wFADNADH peroxidase1.11.1.10.459
1icqFMN12-oxophytodienoate reductase 11.3.1.420.459
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.459
1t2cNAIL-lactate dehydrogenase1.1.1.270.459
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.459
3hlwCE3Beta-lactamase/0.459
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.459
3lsmSFDPyranose 2-oxidase/0.459
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.459
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.459
1h60STRPentaerythritol tetranitrate reductase/0.458
2iko7IGRenin3.4.23.150.458
3ai3NDPNADPH-sorbose reductase/0.458
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.458
3h06VBPGlutamate receptor 2/0.458
3in6FMNUncharacterized protein/0.458
3pftFMNFlavin reductase/0.458
4p5aFADFlavin-dependent thymidylate synthase/0.458
4q0kGA3Phytohormone-binding protein/0.458
1h50FMNPentaerythritol tetranitrate reductase/0.457
1h51FMNPentaerythritol tetranitrate reductase/0.457
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.457
2a92NAIL-lactate dehydrogenase/0.457
2dc1NADProbable L-aspartate dehydrogenase/0.457
2g1r3IGRenin3.4.23.150.457
2gjlFMNNitronate monooxygenase1.13.12.160.457
2iyfERYOleandomycin glycosyltransferase2.4.10.457
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.457
3a3gDLZLumazine protein/0.457
3cluFADElectron transfer flavoprotein subunit alpha/0.457
3lpiZ74Beta-secretase 13.4.23.460.457
3lpjZ75Beta-secretase 13.4.23.460.457
3mx5UTPNucleoprotein/0.457
3sxjSAMPutative methyltransferase/0.457
3toxNAPPutative oxidoreductase/0.457
4y3jHICEndothiapepsin3.4.23.220.457
5irnADPNucleotide binding oligomerization domain containing 2/0.457
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.456
1gky5GPGuanylate kinase2.7.4.80.456
2vbdV10Isopenicillin N synthase1.21.3.10.456
3b70NAPEnoyl reductase LovC10.456
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
3muoZPRProlyl endopeptidase/0.456
4bfzZVZPantothenate kinase2.7.1.330.456
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.456
4lxa1YSBeta-secretase 13.4.23.460.456
4m4922YL-lactate dehydrogenase A chain1.1.1.270.456
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
2wf4ZY4Beta-secretase 13.4.23.460.455
3b6zCO7Enoyl reductase LovC10.455
3clsFADElectron transfer flavoprotein subunit alpha/0.455
3gwfNAPCyclohexanone monooxygenase/0.455
3intFDAUDP-galactopyranose mutase5.4.99.90.455
3ivxFG6Pantothenate synthetase6.3.2.10.455
3rvhHQ2Lysine-specific demethylase 4A1.14.110.455
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.455
4gid0GHBeta-secretase 13.4.23.460.455
1xvaSAMGlycine N-methyltransferase2.1.1.200.454
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.454
3dk4FADGlutathione reductase, mitochondrial1.8.1.70.454
3dv5BAVBeta-secretase 13.4.23.460.454
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3h86AP5Adenylate kinase/0.454
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.453
1w6hTITPlasmepsin-23.4.23.390.453
1x1cSAHC-20 methyltransferase/0.453
2ahrNAPPyrroline-5-carboxylate reductase/0.453
2bjfDXCCholoylglycine hydrolase3.5.1.240.453
2cftPLPPyridoxal phosphate phosphatase/0.453
2xfyACXBeta-amylase3.2.1.20.453
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.453
3nsh957Beta-secretase 13.4.23.460.453
3tneRITCandidapepsin-13.4.23.240.453
4b63FADL-ornithine N(5)-monooxygenase/0.453
4i0i957Beta-secretase 13.4.23.460.453
1dljUGAUDP-glucose 6-dehydrogenase/0.452
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.452
1icpFMN12-oxophytodienoate reductase 11.3.1.420.452
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.452
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.452
1rfvADPPyridoxal kinase2.7.1.350.452
1tqf32PBeta-secretase 13.4.23.460.452
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.452
3c212BADNA integrity scanning protein DisA/0.452
3ekuCY9Actin-5C/0.452
3fstFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.452
3qbhQBHBeta-secretase 13.4.23.460.452
3r7kFDAProbable acyl CoA dehydrogenase/0.452
3veu0GOBeta-secretase 13.4.23.460.452
4b1e6T6Beta-secretase 13.4.23.460.452
4mihFADPyranose 2-oxidase1.1.3.100.452
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.452
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.452
1dirNADDihydropteridine reductase1.5.1.340.451
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.451
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.451
2g1o2IGRenin3.4.23.150.451
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.451
2x06NADL-sulfolactate dehydrogenase/0.451
2z1mNDPGDP-mannose 4,6-dehydratase/0.451
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.451
3ai2NDPNADPH-sorbose reductase/0.451
3cid318Beta-secretase 13.4.23.460.451
3hx4ANPCalmodulin-domain protein kinase 1/0.451
3p62FMNPentaerythritol tetranitrate reductase/0.451
4a8v2ANMajor pollen allergen Bet v 1-J/0.451
4bfxZVXPantothenate kinase2.7.1.330.451
4ead0NPThymidine phosphorylase2.4.2.40.451
4fxy0W2Neurolysin, mitochondrial3.4.24.160.451
4gddNAIUDP-galactopyranose mutase/0.451
4jicFMNGTN Reductase/0.451
4rnuFMNNADPH dehydrogenase 11.6.99.10.451
4rvfTYDD-mycarose 3-C-methyltransferase/0.451
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.451
1beuIPLTryptophan synthase alpha chain/0.450
1x1bSAHC-20 methyltransferase/0.450
2ejvNADL-threonine 3-dehydrogenase/0.450
2g8yNADHydroxycarboxylate dehydrogenase B/0.450
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.450
2hizLIJBeta-secretase 13.4.23.460.450
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.450
2zsaADPPantothenate kinase2.7.1.330.450
3ixj586Beta-secretase 13.4.23.460.450
3kkzSAMUncharacterized protein/0.450
3vg10GTBeta-secretase 13.4.23.460.450
4f5yC2EStimulator of interferon genes protein/0.450
4yryFADGlutamate synthase, beta subunit/0.450
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.449
1nzdUPGDNA beta-glucosyltransferase/0.449
1pz0NAPProtein IolS1.1.10.449
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.449
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.449
2igoFADPyranose 2-oxidase/0.449
2omeNADC-terminal-binding protein 2/0.449
2xpuTDCTetracycline repressor protein class D/0.449
3rsv3RSBeta-secretase 13.4.23.460.449
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
4b65FADL-ornithine N(5)-monooxygenase/0.449
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.449
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4opgFDAConserved Archaeal protein/0.449
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.449
4yaw2AMNADPH--cytochrome P450 reductase/0.449
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.448
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.448
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.448
1h73ANPHomoserine kinase2.7.1.390.448
1nzfUPGDNA beta-glucosyltransferase/0.448
1rfuADPPyridoxal kinase2.7.1.350.448
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.448
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.448
3hl0NADMaleylacetate reductase/0.448
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.448
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.448
3mj4URMUDP-galactopyranose mutase/0.448
3pi53P5Beta-secretase 13.4.23.460.448
4xguADPPutative pachytene checkpoint protein 2/0.448
4yaoFMNNADPH--cytochrome P450 reductase/0.448
5d3qGDPDynamin-13.6.5.50.448
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.447
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.447
1txtCAAHMG-CoA synthase/0.447
2dsgSAHDiphthine synthase/0.447
2g21L1BRenin3.4.23.150.447
2gs9SAHUncharacterized protein/0.447
2hfuMEVMevalonate kinase/0.447
2i4qUA4Renin3.4.23.150.447
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.447
2vouFAD2,6-dihydroxypyridine 3-monooxygenase1.14.13.100.447
3clrFADElectron transfer flavoprotein subunit alpha/0.447
3duyAFJBeta-secretase 13.4.23.460.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ggoNAIPrephenate dehydrogenase/0.447
3he3FADUDP-galactopyranose mutase/0.447
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.447
3u9eCOALmo1369 protein/0.447
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.447
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4egbNADdTDP-glucose 4,6-dehydratase/0.447
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.447
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.447
4qaiFMNNADPH dehydrogenase/0.447
4xfjANPArgininosuccinate synthase/0.447
1msmJE2Gag-Pol polyprotein3.4.23.160.446
1odcA8BAcetylcholinesterase3.1.1.70.446
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.446
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.446
2fznFADBifunctional protein PutA1.5.5.20.446
2g1y5IGRenin3.4.23.150.446
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.446
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.446
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.446
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.446
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.446
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3cltFADElectron transfer flavoprotein subunit alpha/0.446
3dk8FADGlutathione reductase, mitochondrial1.8.1.70.446
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.446
3k4cFADPyranose 2-oxidase/0.446
4b63NAPL-ornithine N(5)-monooxygenase/0.446
4ewo996Beta-secretase 13.4.23.460.446
4j31FADKynurenine 3-monooxygenase/0.446
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.446
1e3lNADAlcohol dehydrogenase 41.1.1.10.445
1eveE20Acetylcholinesterase3.1.1.70.445
1i6kTYMTryptophan--tRNA ligase6.1.1.20.445
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.445
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.445
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
2c20NADUDP-glucose 4-epimerase/0.445
2he5NDPAldo-keto reductase family 1 member C211.1.10.445
2rcyNAPPyrroline-5-carboxylate reductase/0.445
3qgf46FGenome polyprotein2.7.7.480.445
3qwbNDPProbable quinone oxidoreductase1.6.5.50.445
3vdqNAD3-hydroxybutyrate dehydrogenase/0.445
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.445
4b4vL34Bifunctional protein FolD/0.445
4b68FADL-ornithine N(5)-monooxygenase/0.445
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.445
4lisNADUDP-glucose 4-epimerase (Eurofung)/0.445
4p63NADProbable deoxyhypusine synthase2.5.1.460.445
4rflNDPGlycerol-1-phosphate dehydrogenase [NAD(P)+]/0.445
1g6kNADGlucose 1-dehydrogenase1.1.1.470.444
1yw8A75Methionine aminopeptidase 2/0.444
1z41FMNNADPH dehydrogenase/0.444
2f3rG5PGuanylate kinase2.7.4.80.444
2g20L1ARenin3.4.23.150.444
2qbuSAHPrecorrin-2 methyltransferase/0.444
2wezZYEBeta-secretase 13.4.23.460.444
2xgs44PUncharacterized protein/0.444
3bk2U5PRibonuclease J/0.444
3c1y2BADNA integrity scanning protein DisA/0.444
3f1kNAPUncharacterized oxidoreductase YciK10.444
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.444
3lqsPSZD-alanine aminotransferase2.6.1.210.444
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.444
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.444
4dfg0JVGag-Pol polyprotein3.4.23.160.444
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.444
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.444
4fm80UQBeta-secretase 13.4.23.460.444
4qxp1YEStimulator of interferon genes protein/0.444
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.444
5jscFADPutative acyl-CoA dehydrogenase/0.444
5kwvANPPantothenate synthetase/0.444
1fxsNAPGDP-L-fucose synthase/0.443
1h62ANBPentaerythritol tetranitrate reductase/0.443
1hi0GTPRNA-directed RNA polymerase2.7.7.480.443
1kfbIGPTryptophan synthase alpha chain/0.443
1pfyMSPMethionine--tRNA ligase6.1.1.100.443
1szfFMNCytochrome b2, mitochondrial1.1.2.30.443
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.443
2is0I03Beta-secretase 13.4.23.460.443
2ylrNAPPhenylacetone monooxygenase1.14.13.920.443
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.443
2zjmF1MBeta-secretase 13.4.23.460.443
3gegNADShort-chain dehydrogenase/reductase SDR/0.443
3ig6438Urokinase-type plasminogen activator3.4.21.730.443
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.443
3kpbSAMUncharacterized protein MJ0100/0.443
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.443
3wquATPCell division protein FtsA/0.443
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.443
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.443
4emtC2EStimulator of interferon genes protein/0.443
4i1c1BEBeta-secretase 13.4.23.460.443
4j0v1H7Beta-secretase 13.4.23.460.443
4lcjNADC-terminal-binding protein 2/0.443
5af7FADAcyl-CoA dehydrogenase/0.443
1ay0TPPTransketolase 12.2.1.10.442
1bp6UMPThymidylate synthase/0.442
1cnfFADNitrate reductase [NADH]1.7.1.10.442
1jedADPSulfate adenylyltransferase/0.442
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1lf3EH5Plasmepsin-23.4.23.390.442
1mj9COAHistone acetyltransferase ESA1/0.442
1q84TZ4Acetylcholinesterase3.1.1.70.442
2b58COADiamine acetyltransferase 1/0.442
2cbrA80Cellular retinoic acid-binding protein 1/0.442
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.442
2gz7D3FOrf1a polyprotein/0.442
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.442
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.442
3abxRCBGlucanase/0.442
3cwqADPParA family chromosome partitioning protein/0.442
3ieuGDPGTPase Era/0.442
3ukfGDUUDP-galactopyranose mutase/0.442
3ukkFADUDP-galactopyranose mutase/0.442
3uoxFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.442
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.442
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.442
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.442
4z26FADPutative GMC-type oxidoreductase R13510.442
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.442
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.442
1amoFMNNADPH--cytochrome P450 reductase/0.441
1e3eNAIAlcohol dehydrogenase 41.1.1.10.441
1h63FMNPentaerythritol tetranitrate reductase/0.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.441
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.441
2ck3ANPATP synthase subunit alpha, mitochondrial/0.441
2ck3ANPATP synthase subunit beta, mitochondrial3.6.3.140.441
2futH1SHeparin and heparin-sulfate lyase/0.441
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.441
2p4j23IBeta-secretase 13.4.23.460.441
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.441
2whqHI6Acetylcholinesterase3.1.1.70.441
2yj5ATPCopper-transporting ATPase/0.441
3ahn3A1Oligopeptidase/0.441
3cosNADAlcohol dehydrogenase 41.1.1.10.441
3dv1AR9Beta-secretase 13.4.23.460.441
3eksCY9Actin-5C/0.441
3fpzAHZThiamine thiazole synthase/0.441
3keuATPPyridoxal kinase2.7.1.350.441
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.441
4an4DUDPutative glycosyl transferase/0.441
4ap3FADSteroid monooxygenase/0.441
4bfuZVUPantothenate kinase2.7.1.330.441
4ctkSAMGenome polyprotein/0.441
4f9gC2EStimulator of interferon genes protein/0.441
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.441
4j75TYMTryptophan--tRNA ligase/0.441
4m5pFMNNADPH dehydrogenase/0.441
4ycpFMNtRNA-dihydrouridine(16) synthase/0.441
5dp2NAPCurF/0.441
1icsFMN12-oxophytodienoate reductase 11.3.1.420.440
1k7fIAVTryptophan synthase alpha chain/0.440
1udbUFGUDP-glucose 4-epimerase5.1.3.20.440
2c29NAPDihydroflavonol 4-reductase/0.440
2dfvNADL-threonine 3-dehydrogenase/0.440
2ha6SCKAcetylcholinesterase3.1.1.70.440
2wwjY28Lysine-specific demethylase 4A/0.440
2znnS44Peroxisome proliferator-activated receptor alpha/0.440
3akn11DFatty acid-binding protein, intestinal/0.440
3djgFADGlutathione reductase, mitochondrial1.8.1.70.440
3f3sNADLambda-crystallin homolog/0.440
3ic9FADPutative dihydrolipoamide dehydrogenase/0.440
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.440
3mk6ACOPantothenate kinase 32.7.1.330.440
3oixFMNDihydroorotate dehydrogenase/0.440
3r2fPB0Beta-secretase 13.4.23.460.440
3t7x4SHEndothiapepsin3.4.23.220.440
3ukoNADAlcohol dehydrogenase class-3/0.440
3vyeVYERenin3.4.23.150.440
3wfjNAD2-dehydropantoate 2-reductase/0.440
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.440
4emwFADCoenzyme A disulfide reductase/0.440
4fqsLYAThymidylate synthase ThyA/0.440
4gdcNDPUDP-galactopyranose mutase/0.440
4k9h1QUBeta-secretase 13.4.23.460.440
4nv14TGFormyl transferase/0.440
4yaiNAIC alpha-dehydrogenase/0.440
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
5ckuFADL-ornithine N(5)-monooxygenase/0.440