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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ayp43ASerine/threonine-protein kinase Chk12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ayp43ASerine/threonine-protein kinase Chk12.7.11.11.000
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.656
2hog710Serine/threonine-protein kinase Chk12.7.11.10.621
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.612
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.609
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.605
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.602
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.598
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.595
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.594
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.592
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.590
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.590
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.586
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.585
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.583
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.578
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.578
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.577
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.577
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.577
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.576
1zys199Serine/threonine-protein kinase Chk12.7.11.10.575
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.575
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.574
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.573
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.572
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.572
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.569
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.569
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.568
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.568
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.567
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.565
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.564
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.562
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.561
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.559
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.559
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.558
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.557
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.555
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.553
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.551
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.551
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.549
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.548
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.548
3a62STURibosomal protein S6 kinase beta-12.7.11.10.547
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.546
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.544
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.544
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.543
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.543
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.542
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.542
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.542
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.541
4hvh19RTyrosine-protein kinase JAK32.7.10.20.536
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.535
1pkdUCNCyclin-dependent kinase 22.7.11.220.534
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.534
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.534
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.534
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.534
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.533
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.533
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.530
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.530
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.530
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.528
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.527
4hvg19QTyrosine-protein kinase JAK32.7.10.20.527
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.526
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.526
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.526
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.525
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.524
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.524
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.524
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.523
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.522
1wvxBD4Death-associated protein kinase 12.7.11.10.520
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.520
3gu6ADPDeath-associated protein kinase 12.7.11.10.520
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.520
3zh8C58Protein kinase C iota type2.7.11.130.520
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.520
4nka2K7Fibroblast growth factor receptor 1/0.519
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.518
4c62XWWTyrosine-protein kinase JAK2/0.518
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.518
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.517
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.517
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.516
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.516
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.515
1aq1STUCyclin-dependent kinase 22.7.11.220.514
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.513
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.510
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.510
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.510
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.510
3gubGUBDeath-associated protein kinase 12.7.11.10.509
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.509
3tnwF18Cyclin-dependent kinase 22.7.11.220.509
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.508
4j97ACPFibroblast growth factor receptor 2/0.508
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.507
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.507
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.507
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.507
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.507
3eb0DRKUncharacterized protein/0.506
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.506
4gk3L87Ephrin type-A receptor 32.7.10.10.505
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.505
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.504
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.503
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.503
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.503
5aaaVGHALK tyrosine kinase receptor2.7.10.10.503
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.502
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.502
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.502
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.501
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.501
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.501
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.501
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.500
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.500
1yvj4STTyrosine-protein kinase JAK32.7.10.20.499
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.499
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.499
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.499
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.499
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.498
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.498
3js2VM1Fibroblast growth factor receptor 1/0.498
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.498
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.498
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.497
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.497
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.497
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.496
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.494
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.494
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.494
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.494
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.493
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.493
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.493
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.493
3ztxZTXAurora kinase B-A2.7.11.10.493
5dr9SKEAurora kinase A2.7.11.10.493
1zrzBI1Protein kinase C iota type2.7.11.130.492
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.492
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.492
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.492
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.492
3s4qNK0Mitogen-activated protein kinase 14/0.492
4f640S8Fibroblast growth factor receptor 1/0.492
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.491
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.491
4gk2L66Ephrin type-A receptor 32.7.10.10.491
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.491
2wipP49Cyclin-dependent kinase 22.7.11.220.490
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.490
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.490
3i60E86Mitogen-activated protein kinase 12.7.11.240.490
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
2i40BLZCyclin-dependent kinase 22.7.11.220.489
2z2w770Wee1-like protein kinase2.7.10.20.489
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.489
3r9dX6BCyclin-dependent kinase 22.7.11.220.489
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.489
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.488
4bcqTJFCyclin-dependent kinase 22.7.11.220.488
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.488
4hvi19STyrosine-protein kinase JAK32.7.10.20.488
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.488
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.487
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.487
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.487
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.487
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.486
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.486
2yn8STUEphrin type-B receptor 42.7.10.10.486
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.486
4f630S7Fibroblast growth factor receptor 1/0.486
1e9hINRCyclin-dependent kinase 22.7.11.220.485
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.485
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
5auwQUEDeath-associated protein kinase 12.7.11.10.485
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.484
4dce0JFALK tyrosine kinase receptor2.7.10.10.484
5aabVGHALK tyrosine kinase receptor2.7.10.10.484
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.483
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.483
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.483
4erwSTUCyclin-dependent kinase 22.7.11.220.483
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.483
4nks2M2Fibroblast growth factor receptor 1/0.483
5auxKMPDeath-associated protein kinase 12.7.11.10.483
1xjdSTUProtein kinase C theta type2.7.11.130.482
3bhy7CPDeath-associated protein kinase 3/0.482
3bqr4RBDeath-associated protein kinase 3/0.482
3emg685Tyrosine-protein kinase SYK2.7.10.20.482
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.482
4btkDTQTau-tubulin kinase 12.7.11.10.482
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.482
5av2KMPDeath-associated protein kinase 12.7.11.10.482
5av4GENDeath-associated protein kinase 12.7.11.10.482
2vd5BI8Myotonin-protein kinase2.7.11.10.481
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.481
3rkb12ZCyclin-dependent kinase 22.7.11.220.481
3sheI85MAP kinase-activated protein kinase 32.7.11.10.481
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.481
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.481
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.480
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.480
3uli1N3Cyclin-dependent kinase 22.7.11.220.480
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.480
3zewSTUEphrin type-B receptor 42.7.10.10.480
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.480
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.479
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.478
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.478
2x1nX1NCyclin-dependent kinase 22.7.11.220.478
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.478
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.478
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.478
1finATPCyclin-dependent kinase 22.7.11.220.477
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.477
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.477
5auzGENDeath-associated protein kinase 12.7.11.10.477
2itzIREEpidermal growth factor receptor2.7.10.10.476
2uzbC75Cyclin-dependent kinase 22.7.11.220.476
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.476
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.475
2cchATPCyclin-dependent kinase 22.7.11.220.475
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.475
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.475
4fx360KCyclin-dependent kinase 22.7.11.220.475
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.474
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.474
2j9mPY8Cyclin-dependent kinase 22.7.11.220.474
2vrx447Aurora kinase B-A2.7.11.10.474
3lctADPALK tyrosine kinase receptor2.7.10.10.474
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.474
4ez50RSCyclin-dependent kinase 62.7.11.220.474
4fnzNZFALK tyrosine kinase receptor2.7.10.10.474
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.473
2x6dX6DAurora kinase A2.7.11.10.473
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.473
4e4m0NHTyrosine-protein kinase JAK2/0.473
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.473
1ol6ATPAurora kinase A2.7.11.10.471
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.471
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.471
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.471
4jia1K3Tyrosine-protein kinase JAK2/0.471
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.471
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.471
2bujSTUSerine/threonine-protein kinase 16/0.470
4bcmT7ZCyclin-dependent kinase 22.7.11.220.470
4gu94GUFocal adhesion kinase 12.7.10.20.470
4qnaX11Serine/threonine-protein kinase 242.7.11.10.470
4utdACPAurora kinase A2.7.11.10.470
2vgoAD5Aurora kinase B-A2.7.11.10.469
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.469
3nux3NVCyclin-dependent kinase 62.7.11.220.469
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.469
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.468
2py3ACPFibroblast growth factor receptor 2/0.468
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.468
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.468
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.468
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.468
1agwSU2Fibroblast growth factor receptor 1/0.467
1u54ACPActivated CDC42 kinase 1/0.467
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.467
2yfxVGHALK tyrosine kinase receptor2.7.10.10.467
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.467
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.467
4fyn0VETyrosine-protein kinase SYK2.7.10.20.467
4jqeANPCasein kinase II subunit alpha2.7.11.10.467
4nj32KDCyclin-dependent kinase 22.7.11.220.467
2h96893Mitogen-activated protein kinase 82.7.11.240.466
2itqITQEpidermal growth factor receptor2.7.10.10.466
2of4979Tyrosine-protein kinase Lck2.7.10.20.466
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.466
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.466
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.466
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.466
1oecAA2Fibroblast growth factor receptor 2/0.465
2itnANPEpidermal growth factor receptor2.7.10.10.465
2uzlC94Cyclin-dependent kinase 22.7.11.220.465
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.465
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.465
4iebANPCalmodulin-domain protein kinase 1/0.465
1fvv107Cyclin-dependent kinase 22.7.11.220.464
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.464
2c4g514Cyclin-dependent kinase 22.7.11.220.464
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.464
3biz61EWee1-like protein kinase2.7.10.20.464
3hx4ANPCalmodulin-domain protein kinase 1/0.464
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.464
4ansVGHALK tyrosine kinase receptor2.7.10.10.464
1gih1PUCyclin-dependent kinase 22.7.11.220.463
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.463
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.463
3w2sW2REpidermal growth factor receptor2.7.10.10.463
3zep1NXTyrosine-protein kinase JAK32.7.10.20.463
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.463
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.463
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.463
4yuqKS1Calmodulin-like domain protein kinase/0.463
2acxANPG protein-coupled receptor kinase 62.7.11.160.462
2j0j4STFocal adhesion kinase 12.7.10.20.462
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
5aacVGHALK tyrosine kinase receptor2.7.10.10.462
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.461
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.461
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.461
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.461
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.461
4gmy0X5Tyrosine-protein kinase JAK2/0.461
4j95ACPFibroblast growth factor receptor 2/0.461
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.460
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3c4xATPRhodopsin kinase/0.460
3ral04ZCyclin-dependent kinase 22.7.11.220.460
3t8oATPRhodopsin kinase/0.460
3vjoANPEpidermal growth factor receptor2.7.10.10.460
4fv9E71Mitogen-activated protein kinase 12.7.11.240.460
4i22IREEpidermal growth factor receptor2.7.10.10.460
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.460
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
2xp2VGHALK tyrosine kinase receptor2.7.10.10.459
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.459
4d58BI9Focal adhesion kinase 12.7.10.20.459
4qmpDKISerine/threonine-protein kinase 242.7.11.10.459
1cm8ANPMitogen-activated protein kinase 12/0.458
1ivp1ZKGag-Pol polyprotein/0.458
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.458
2in6839Wee1-like protein kinase2.7.10.20.458
2vu3LZECyclin-dependent kinase 22.7.11.220.458
2xikJ60Serine/threonine-protein kinase 252.7.11.10.458
3ezvEZVCyclin-dependent kinase 22.7.11.220.458
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
4bcnT9NCyclin-dependent kinase 22.7.11.220.458
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
4erkOLOMitogen-activated protein kinase 12.7.11.240.458
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.458
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.458
4qmySTUSerine/threonine-protein kinase 242.7.11.10.458
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.457
3ka0MK3MAP kinase-activated protein kinase 22.7.11.10.457
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.457
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3qxpX64Cyclin-dependent kinase 22.7.11.220.457
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.457
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.457
4jbqVX6Aurora kinase A2.7.11.10.457
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.457
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
1oiyN41Cyclin-dependent kinase 22.7.11.220.456
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.456
2v7a627Tyrosine-protein kinase ABL12.7.10.20.456
2wpa889Cyclin-dependent kinase 22.7.11.220.456
2yac937Serine/threonine-protein kinase PLK12.7.11.210.456
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.456
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.456
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.456
4ccbOFGALK tyrosine kinase receptor2.7.10.10.456
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.456
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.456
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.456
4kshHTTDNA gyrase subunit B/0.456
4o0wADNAurora kinase A2.7.11.10.456
2c3qGTXGlutathione S-transferase theta-12.5.1.180.455
2j0m4STFocal adhesion kinase 12.7.10.20.455
2pvnP63Casein kinase II subunit alpha2.7.11.10.455
3b2tM33Fibroblast growth factor receptor 2/0.455
3le62BZCyclin-dependent kinase 22.7.11.220.455
3qc9ADPRhodopsin kinase/0.455
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.455
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.455
4dgo0JWCasein kinase II subunit alpha2.7.11.10.455
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.455
5e8xSTUTGF-beta receptor type-12.7.11.300.455
1m17AQ4Epidermal growth factor receptor2.7.10.10.454
1pyePM1Cyclin-dependent kinase 22.7.11.220.454
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.454
2f2cAP9Cyclin-dependent kinase 62.7.11.220.454
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.454
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.454
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.454
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.454
3q5iANPProtein kinase, putative/0.454
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.454
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.454
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.454
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.454
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.454
2of2547Tyrosine-protein kinase Lck2.7.10.20.453
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4jrvKJVEpidermal growth factor receptor2.7.10.10.453
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2qo9ANPEphrin type-A receptor 32.7.10.10.452
2vv9IM9Cyclin-dependent kinase 22.7.11.220.452
3cr0809Wee1-like protein kinase2.7.10.20.452
3nup3NUCyclin-dependent kinase 62.7.11.220.452
3t113T1Gag-Pol polyprotein3.4.23.160.452
3tucFPWTyrosine-protein kinase SYK2.7.10.20.452
3w32W32Epidermal growth factor receptor2.7.10.10.452
4eok4SPCyclin-dependent kinase 22.7.11.220.452
4oavACP2-5A-dependent ribonuclease3.1.260.452
4wsqKSAAP2-associated protein kinase 12.7.11.10.452
5f8eSAHPossible transcriptional regulatory protein/0.452
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1t7i017Gag-Pol polyprotein3.4.23.160.451
1xl2189Gag-Pol polyprotein3.4.23.160.451
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.451
2bheBRYCyclin-dependent kinase 22.7.11.220.451
2itpAEEEpidermal growth factor receptor2.7.10.10.451
2pwlACPFibroblast growth factor receptor 2/0.451
2vgpAD6Aurora kinase B-A2.7.11.10.451
2xa4AZ5Tyrosine-protein kinase JAK2/0.451
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.451
3ac1KZITyrosine-protein kinase Lck2.7.10.20.451
3c50ADPRhodopsin kinase/0.451
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.451
4cd0AWJALK tyrosine kinase receptor2.7.10.10.451
4hjoAQ4Epidermal growth factor receptor2.7.10.10.451
4jr3KJREpidermal growth factor receptor2.7.10.10.451
4o0sADNAurora kinase A2.7.11.10.451
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.451
1xkkFMMEpidermal growth factor receptor2.7.10.10.450
2ittAEEEpidermal growth factor receptor2.7.10.10.450
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.450
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
3oxv478Gag-Pol polyprotein3.4.23.160.450
3rmf20ZCyclin-dependent kinase 22.7.11.220.450
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.450
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.450
3w18N13Aurora kinase A2.7.11.10.450
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.450
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4fob0USALK tyrosine kinase receptor2.7.10.10.450
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.450
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.450
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.449
2eb3ANPEpidermal growth factor receptor2.7.10.10.449
2qo7ANPEphrin type-A receptor 32.7.10.10.449
2w05FRTCyclin-dependent kinase 22.7.11.220.449
3gu5ANPDeath-associated protein kinase 12.7.11.10.449
3r7iX9ICyclin-dependent kinase 22.7.11.220.449
4eomATPCyclin-dependent kinase 22.7.11.220.449
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.449
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.449
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2c6tDT5Cyclin-dependent kinase 22.7.11.220.448
2i0ePDSProtein kinase C beta type2.7.11.130.448
2uzeC95Cyclin-dependent kinase 22.7.11.220.448
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.448
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.448
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.448
4xlvACPInsulin receptor2.7.10.10.448
1vjy460TGF-beta receptor type-12.7.11.300.447
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
2ijmADPFocal adhesion kinase 12.7.10.20.447
2io6330Wee1-like protein kinase2.7.10.20.447
2j7t274Serine/threonine-protein kinase 102.7.11.10.447
2p33J07Mitogen-activated protein kinase 102.7.11.240.447
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.447
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.447
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.447
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3oroAGSSerine/threonine protein kinase/0.447
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.447
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.447
4anqVGHALK tyrosine kinase receptor2.7.10.10.447
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
4i231C9Epidermal growth factor receptor2.7.10.10.447
4ic7ANPMitogen-activated protein kinase 72.7.11.240.447
5auuLU2Death-associated protein kinase 12.7.11.10.447
5dpvSKEAurora kinase A2.7.11.10.447
1oguST8Cyclin-dependent kinase 22.7.11.220.446
2bkzSBCCyclin-dependent kinase 22.7.11.220.446
2c5nCK8Cyclin-dependent kinase 22.7.11.220.446
2dwbANPAurora kinase A2.7.11.10.446
2qd7065Gag-Pol polyprotein3.4.23.160.446
2r3wG3GGag-Pol polyprotein3.4.23.160.446
2y6o1N1Ephrin type-A receptor 42.7.10.10.446
3adaNADSubunit alpha of sarocosine oxidase/0.446
3c4wATPRhodopsin kinase/0.446
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.446
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.446
3rk507ZCyclin-dependent kinase 22.7.11.220.446
4fkw62KCyclin-dependent kinase 22.7.11.220.446
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.446
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.446
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.446
1bygSTUTyrosine-protein kinase CSK/0.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1mesDMPGag-Pol polyprotein3.4.23.160.445
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.445
3lfqA28Cyclin-dependent kinase 22.7.11.220.445
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.445
4o0uADNAurora kinase A2.7.11.10.445
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4wboANWRhodopsin kinase/0.445
5dr6SKEAurora kinase A2.7.11.10.445
2w17I19Cyclin-dependent kinase 22.7.11.220.444
2xneASHAurora kinase A2.7.11.10.444
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.444
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.444
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.444
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
5f0a1FBcGMP-dependent protein kinase, putative/0.444
1h1r6CPCyclin-dependent kinase 22.7.11.220.443
1ir3ANPInsulin receptor2.7.10.10.443
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
2pmnK51Protein kinase 7/0.443
2pvyACPFibroblast growth factor receptor 2/0.443
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.443
3du8553Glycogen synthase kinase-3 beta2.7.11.260.443
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.443
3w33W19Epidermal growth factor receptor2.7.10.10.443
4aqc88ATyrosine-protein kinase JAK2/0.443
4e6d0NUTyrosine-protein kinase JAK2/0.443
4fv6E57Mitogen-activated protein kinase 12.7.11.240.443
4jbpYPHAurora kinase A2.7.11.10.443
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.443
4loqSB4Mitogen-activated protein kinase 14/0.443
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.442
2hk51BMTyrosine-protein kinase HCK2.7.10.20.442
3nwxKVSGag-Pol polyprotein3.4.23.160.442
4b99R4LMitogen-activated protein kinase 72.7.11.240.442
4ix6ADPUncharacterized protein/0.442
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.442
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.442
1oi9N20Cyclin-dependent kinase 22.7.11.220.441
2b7zMK1Gag-Pol polyprotein/0.441
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.441
3a60STURibosomal protein S6 kinase beta-12.7.11.10.441
3blrCPBCyclin-dependent kinase 92.7.11.220.441
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.441
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.441
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.441
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.441
4fnyI3KALK tyrosine kinase receptor2.7.10.10.441
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.441
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.441
5av3KMPDeath-associated protein kinase 12.7.11.10.441
5dt0SKEAurora kinase A2.7.11.10.441
1a8g2Z4Gag-Pol polyprotein3.4.23.160.440
1ke5LS1Cyclin-dependent kinase 22.7.11.220.440
2c475IDCasein kinase I isoform gamma-2/0.440
2vtqLZACyclin-dependent kinase 22.7.11.220.440
2w06FRVCyclin-dependent kinase 22.7.11.220.440
2w1eL0EAurora kinase A2.7.11.10.440
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.440
2xngA0HAurora kinase A2.7.11.10.440
2xyuQ9GEphrin type-A receptor 42.7.10.10.440
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.440
3be9P04Casein kinase II subunit alpha2.7.11.10.440
3d1xROCGag-Pol polyprotein3.4.23.160.440
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.440
4bgg844Activin receptor type-12.7.11.300.440
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.440
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.440