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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1on3MCAMethylmalonyl-CoA carboxyltransferase 12S subunit2.1.3.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1on3MCAMethylmalonyl-CoA carboxyltransferase 12S subunit2.1.3.11.000
3ixp834Ecdysone receptor/0.509
2a5kAZPReplicase polyprotein 1ab3.4.220.505
3pgqGY3Acetyl-CoA carboxylase/0.500
3qt62P0Mevalonate diphosphate decarboxylase/0.495
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.492
2g1s4IGRenin3.4.23.150.492
2a94AP0L-lactate dehydrogenase1.1.1.270.491
2i4qUA4Renin3.4.23.150.491
3lqfNADGalactitol dehydrogenase/0.491
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.489
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.488
2g1r3IGRenin3.4.23.150.486
2yee2ECHeat shock protein HSP 90-alpha/0.485
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.485
3uylTYDProbable NDP-rhamnosyltransferase/0.485
4dbzNDPPutative ketoacyl reductase1.3.10.485
2gv8NDPThiol-specific monooxygenase1.14.130.484
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3ai3NDPNADPH-sorbose reductase/0.482
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.481
1xnyBTNPropionyl-CoA carboxylase complex B subunit/0.481
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.480
1uymPU3Heat shock protein HSP 90-beta/0.480
4i1iNADMalate dehydrogenase/0.480
1bwsNDPGDP-L-fucose synthase/0.479
2x0iNAIMalate dehydrogenase/0.479
1uy7PU4Heat shock protein HSP 90-alpha/0.478
4nieNBHNuclear receptor ROR-gamma/0.478
1r2jFADFkbI/0.476
2il2LIXRenin3.4.23.150.475
3ekoPYUHeat shock protein HSP 90-alpha/0.475
1n77ATPGlutamate--tRNA ligase6.1.1.170.474
4a802ANMajor pollen allergen Bet v 1-A/0.474
4cggK5QIntegrase/0.474
1guyNADMalate dehydrogenase/0.473
1kfbIGPTryptophan synthase alpha chain/0.473
1mewXMPInosine-5'-monophosphate dehydrogenase/0.473
2rlcCHDCholoylglycine hydrolase3.5.1.240.473
4cfaWOPIntegrase/0.473
2g247IGRenin3.4.23.150.472
2i7pACOPantothenate kinase 32.7.1.330.472
1eioGCHGastrotropin/0.471
2zcvNDPQuinone oxidoreductase 21.6.5.20.471
3r7kFDAProbable acyl CoA dehydrogenase/0.471
1u0hFOKAdenylate cyclase type 2/0.470
1u0hFOKAdenylate cyclase type 5/0.470
2d29FADAcyl-CoA dehydrogenase/0.470
2iko7IGRenin3.4.23.150.470
2uxoTACHTH-type transcriptional regulator TtgR/0.470
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.470
1bk0ACVIsopenicillin N synthase1.21.3.10.469
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.469
2e1mFADL-glutamate oxidase/0.469
2g1n1IGRenin3.4.23.150.469
2wi6ZZ6Heat shock protein HSP 90-alpha/0.469
4a81DXCMajor pollen allergen Bet v 1-A/0.469
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.467
2bjfDXCCholoylglycine hydrolase3.5.1.240.467
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.467
2ylzFADPhenylacetone monooxygenase1.14.13.920.467
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4a862ANMajor pollen allergen Bet v 1-A/0.467
4jqlVJ6Heat shock protein HSP 90-alpha/0.467
4r21STRCytochrome P450 family 17 polypeptide 2/0.467
2fj1CTCTetracycline repressor protein class D/0.466
2y3sTIRTamL/0.466
3c3xNAPEugenol synthase 11.1.1.3180.466
4ambDUDPutative glycosyl transferase/0.466
4dpuAGSMevalonate diphosphate decarboxylase/0.466
2y60M8FIsopenicillin N synthase1.21.3.10.465
1j49NADD-lactate dehydrogenase1.1.1.280.464
3gkaFMNN-ethylmaleimide reductase/0.464
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.464
4l4eCAMCamphor 5-monooxygenase1.14.15.10.464
1dirNADDihydropteridine reductase1.5.1.340.463
1kp2ATPArgininosuccinate synthase6.3.4.50.463
1t2cNAIL-lactate dehydrogenase1.1.1.270.463
2aa3AP0L-lactate dehydrogenase/0.463
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2iqgF2IBeta-secretase 13.4.23.460.463
2iviACWIsopenicillin N synthase1.21.3.10.463
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.463
3zeiAWHO-acetylserine sulfhydrylase/0.463
4b4vL34Bifunctional protein FolD/0.463
4boeCLRJapanin/0.463
4l4fCAMCamphor 5-monooxygenase1.14.15.10.463
4m6jNDPDihydrofolate reductase1.5.1.30.463
1cscCMCCitrate synthase, mitochondrial2.3.3.10.462
2po7CHDFerrochelatase, mitochondrial4.99.1.10.462
2rhgIGPTryptophan synthase alpha chain/0.462
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.462
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.462
4q0kGA3Phytohormone-binding protein/0.462
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.461
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.461
2iyfERYOleandomycin glycosyltransferase2.4.10.461
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3f03FMNPentaerythritol tetranitrate reductase/0.461
3r4oFU3Heat shock protein HSP 90-alpha/0.461
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.461
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.461
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.460
1v9aSAHUncharacterized protein/0.460
2bt0CT5Heat shock protein HSP 90-alpha/0.460
2dxiATPGlutamate--tRNA ligase6.1.1.170.460
2rqfJH3Hemolymph juvenile hormone binding protein/0.460
2yejZZ3Heat shock protein HSP 90-alpha/0.460
3bnkFMNFlavoredoxin/0.460
3gwfFADCyclohexanone monooxygenase/0.460
4m4922YL-lactate dehydrogenase A chain1.1.1.270.460
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.459
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.459
2c29NAPDihydroflavonol 4-reductase/0.459
2g8yNADHydroxycarboxylate dehydrogenase B/0.459
2xd6XD6ATP-dependent molecular chaperone HSP82/0.459
1dr3TAPDihydrofolate reductase1.5.1.30.458
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.458
2fzwNADAlcohol dehydrogenase class-31.1.1.10.458
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.458
2yeiXQIHeat shock protein HSP 90-alpha/0.458
3zoiM2WIsopenicillin N synthase1.21.3.10.458
4iae1DXAlr2278 protein/0.458
5c77SAHProtein arginine N-methyltransferase SFM1/0.458
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.457
1obnASVIsopenicillin N synthase1.21.3.10.457
1xe65FPPlasmepsin-23.4.23.390.457
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.457
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.457
2z6jTUI2-nitropropane dioxygenase/0.457
3h3t16HCollagen type IV alpha-3-binding protein/0.457
3isjA8DPantothenate synthetase6.3.2.10.457
3wrhCAMCamphor 5-monooxygenase1.14.15.10.457
4b8zNAPGDP-L-fucose synthase1.1.1.2710.457
4dc0NDPPutative ketoacyl reductase1.3.10.457
4kgkGTPUncharacterized protein/0.457
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
1cnfFADNitrate reductase [NADH]1.7.1.10.456
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.456
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
1tehNADAlcohol dehydrogenase class-31.1.1.10.456
2zbaZBATrichothecene 3-O-acetyltransferase/0.456
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.456
3zkyWT4Isopenicillin N synthase1.21.3.10.456
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.456
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.455
1j5pNADL-aspartate dehydrogenase1.4.1.210.455
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1uxkNADMalate dehydrogenase/0.455
2gjlFMNNitronate monooxygenase1.13.12.160.455
2xa4AZ5Tyrosine-protein kinase JAK2/0.455
2xtnGTPGTPase IMAP family member 2/0.455
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.455
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.455
4rquNADAlcohol dehydrogenase class-P/0.455
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.455
5ifiPRXAcetyl-coenzyme A synthetase/0.455
1u1f183Uridine phosphorylase2.4.2.30.454
1wn3HXCPhenylacetic acid degradation protein PaaI/0.454
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
2y3rTRKTamL/0.454
2z6uSAHModification methylase HhaI2.1.1.370.454
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3k974CDHeat shock protein HSP 90-alpha/0.454
3qlrNDPDihydrofolate reductase1.5.1.30.454
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.454
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.454
3vw7VPXProteinase-activated receptor 1/0.454
1c4vIH2Prothrombin3.4.21.50.453
1i59ANPChemotaxis protein CheA2.7.13.30.453
1ma0NADAlcohol dehydrogenase class-31.1.1.10.453
1mjaCOAHistone acetyltransferase ESA1/0.453
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.453
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.453
2e4nSAHDiphthine synthase/0.453
2qbuSAHPrecorrin-2 methyltransferase/0.453
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.453
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.453
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.453
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.453
3vyfVYFRenin3.4.23.150.453
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.453
4j491J1Uncharacterized protein/0.453
4jicFMNGTN Reductase/0.453
5f8eSAHPossible transcriptional regulatory protein/0.453
4s0vSUVOrexin receptor type 2/0.453
1cs4FOKAdenylate cyclase type 2/0.452
1cs4FOKAdenylate cyclase type 5/0.452
1o76CAMCamphor 5-monooxygenase1.14.15.10.452
1tl7FOKAdenylate cyclase type 2/0.452
1tl7FOKAdenylate cyclase type 5/0.452
2c27ACOMycothiol acetyltransferase2.3.1.1890.452
2dsgSAHDiphthine synthase/0.452
2e15SAHDiphthine synthase/0.452
2hpvFMNFMN-dependent NADH-azoreductase1.70.452
2j4lUTPUridylate kinase2.7.4.220.452
2owgSAHDiphthine synthase/0.452
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.452
2vwqNAPGlucose 1-dehydrogenase/0.452
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.452
3c15FOKAdenylate cyclase type 2/0.452
3c15FOKAdenylate cyclase type 5/0.452
3ekrPY9Heat shock protein HSP 90-alpha/0.452
4e5yNDPGDP-L-fucose synthase1.1.1.2710.452
4jlm1NNDeoxycytidine kinase2.7.1.740.452
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.452
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.452
5k7wSAHN6-adenosine-methyltransferase 70 kDa subunit/0.452
1f20FADNitric oxide synthase, brain1.14.13.390.451
1hkuNADC-terminal-binding protein 11.1.10.451
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2djxFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.451
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.451
2o12FMNChorismate synthase/0.451
2qw034Z4-chlorobenzoyl CoA ligase/0.451
3b70NAPEnoyl reductase LovC10.451
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.451
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3nxxNDPDihydrofolate reductase1.5.1.30.451
3r9uFADThioredoxin reductase/0.451
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.451
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.451
4m83ERYOleandomycin glycosyltransferase2.4.10.451
4m9aFDAAcyl-CoA dehydrogenase/0.451
4mqy2CWUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.451
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.450
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.450
1culFOKAdenylate cyclase type 2/0.450
1culFOKAdenylate cyclase type 5/0.450
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.450
1ppjANYCytochrome b/0.450
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.450
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.450
2eldSAHDiphthine synthase/0.450
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.450
2fwzH71Heat shock protein HSP 90-alpha/0.450
2g21L1BRenin3.4.23.150.450
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2huxSAHDiphthine synthase/0.450
2oapANPType II secretion system protein (GspE-2)/0.450
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.450
3d84NDPDihydrofolate reductase1.5.1.30.450
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3k5c0BIBeta-secretase 13.4.23.460.450
3omuIBDHeat shock protein 83/0.450
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4ddhMS0Pantothenate synthetase6.3.2.10.450
4g7gVFVLanosterol 14-alpha-demethylase/0.450
4ipw1G7Mycocyclosin synthase1.14.21.90.450
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.450
4uunNAIL-lactate dehydrogenase/0.450
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.450
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.450
4zohFADPutative oxidoreductase FAD-binding subunit/0.450
5irnADPNucleotide binding oligomerization domain containing 2/0.450
1dr2TAPDihydrofolate reductase1.5.1.30.449
1h50FMNPentaerythritol tetranitrate reductase/0.449
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.449
1xddAAYIntegrin alpha-L/0.449
1yqzCOACoenzyme A disulfide reductase/0.449
2cv1ATPGlutamate--tRNA ligase6.1.1.170.449
2ejjSAHDiphthine synthase/0.449
2ejzSAHDiphthine synthase/0.449
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.449
2xyuQ9GEphrin type-A receptor 42.7.10.10.449
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/0.449
3a0tADPSensor histidine kinase/0.449
3bk2U5PRibonuclease J/0.449
3gvhNADMalate dehydrogenase/0.449
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.449
3r95ACOMccE protein/0.449
4a8v2ANMajor pollen allergen Bet v 1-J/0.449
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.449
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.449
4q73FADBifunctional protein PutA/0.449
1g1aNADdTDP-glucose 4,6-dehydratase/0.448
1hb1OCVIsopenicillin N synthase1.21.3.10.448
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.448
1oc1ASVIsopenicillin N synthase1.21.3.10.448
2givACOHistone acetyltransferase KAT8/0.448
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.448
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.448
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.448
2uxiG50HTH-type transcriptional regulator TtgR/0.448
2y0mACOHistone acetyltransferase KAT8/0.448
2zuiCAMCamphor 5-monooxygenase1.14.15.10.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3ictFADCoenzyme A disulfide reductase/0.448
3n0cFADFlavin-dependent thymidylate synthase2.1.1.1480.448
3tfyCOAN-alpha-acetyltransferase 502.3.10.448
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.448
4xclAGSHeat shock cognate 90 kDa protein/0.448
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.448
1dgmADNAdenosine kinase2.7.1.200.447
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.447
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.447
1x2hLPALipoate-protein ligase A6.3.1.200.447
1yc443PHeat shock protein HSP 90-alpha/0.447
1z69F425,10-methylenetetrahydromethanopterin reductase/0.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2g1y5IGRenin3.4.23.150.447
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.447
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.447
2pchSAHDiphthine synthase/0.447
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
3ft8MOJHeat shock protein HSP 90-alpha/0.447
3gwfNAPCyclohexanone monooxygenase/0.447
3of4FMNNitroreductase/0.447
3ooiSAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2.1.1.430.447
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4e2dFMNDehydrogenase/0.447
4jq4IMNAldo-keto reductase family 1 member C2/0.447
1gcoNADGlucose 1-dehydrogenase1.1.1.470.446
1mczRMNBenzoylformate decarboxylase4.1.1.70.446
1mj9COAHistone acetyltransferase ESA1/0.446
2ccu2D9Heat shock protein HSP 90-alpha/0.446
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.446
2e07SAHDiphthine synthase/0.446
2j08FADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
2jb4A14Isopenicillin N synthase1.21.3.10.446
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.446
2nniMTKCytochrome P450 2C8/0.446
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.446
2wxvWXVCyclin-dependent kinase 22.7.11.220.446
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3fhxPXLPyridoxal kinase2.7.1.350.446
3hl0NADMaleylacetate reductase/0.446
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.446
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.446
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.446
4b63NAPL-ornithine N(5)-monooxygenase/0.446
4bfsZVSPantothenate kinase2.7.1.330.446
4egbNADdTDP-glucose 4,6-dehydratase/0.446
4f5yC2EStimulator of interferon genes protein/0.446
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.446
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
1h62ANBPentaerythritol tetranitrate reductase/0.445
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.445
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.445
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.445
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.445
3h1vTK1Glucokinase2.7.1.20.445
3opdHIEHeat shock protein 83/0.445
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
4a84DXCMajor pollen allergen Bet v 1-A/0.445
4cdmFO1Deoxyribodipyrimidine photolyase/0.445
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.445
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.445
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.445
4loi1YCStimulator of interferon genes protein/0.445
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.445
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.445
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1e3eNAIAlcohol dehydrogenase 41.1.1.10.444
1jqdSAHHistamine N-methyltransferase2.1.1.80.444
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1rneC60Renin3.4.23.150.444
1w6hTITPlasmepsin-23.4.23.390.444
1x8lOXRRetinol dehydratase/0.444
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.444
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.444
2vprTDCTetracycline repressor protein class H/0.444
2yj4ATPCopper-transporting ATPase/0.444
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.444
3b2eADPATPase GET3/0.444
3pm1ETHTH-type transcriptional regulator QacR/0.444
3wswNADL-lactate dehydrogenase/0.444
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.444
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
5c1mCLRMu-type opioid receptor/0.444
4zj8SUVOrexin receptor type 1/0.444
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1fm4DXCMajor pollen allergen Bet v 1-L/0.443
1fmlRTLRetinol dehydratase/0.443
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1pqc444Oxysterols receptor LXR-beta/0.443
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.443
1t85CAMCamphor 5-monooxygenase1.14.15.10.443
1v4sMRKGlucokinase2.7.1.20.443
1w4xFADPhenylacetone monooxygenase1.14.13.920.443
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.443
1xe55FEPlasmepsin-23.4.23.390.443
2i7nACOPantothenate kinase 12.7.1.330.443
2ifaFMNUncharacterized protein/0.443
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.443
2qfoA51Heat shock protein HSP 90-alpha/0.443
2rh9IGPTryptophan synthase alpha chain/0.443
2vbdV10Isopenicillin N synthase1.21.3.10.443
2y4gTIRTamL/0.443
2znnS44Peroxisome proliferator-activated receptor alpha/0.443
3b1dPLSBetaC-S lyase/0.443
3cosNADAlcohol dehydrogenase 41.1.1.10.443
3fwjCAMCamphor 5-monooxygenase1.14.15.10.443
3tneRITCandidapepsin-13.4.23.240.443
3wagTYDGlycosyltransferase/0.443
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.443
4g95OAGDihydrofolate reductase1.5.1.30.443
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4jalSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.443
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.443
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.442
1c7oPPGHemolysin/0.442
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.442
2cftPLPPyridoxal phosphate phosphatase/0.442
2el0SAHDiphthine synthase/0.442
2ikuLIYRenin3.4.23.150.442
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.442
3djjFADGlutathione reductase, mitochondrial1.8.1.70.442
3drcMTXDihydrofolate reductase1.5.1.30.442
3lxiCAMCytochrome P450/0.442
3o0iP54Heat shock protein HSP 90-alpha/0.442
3qgf46FGenome polyprotein2.7.7.480.442
3rpeFADPutative modulator of drug activity/0.442
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.442
4b1bFADThioredoxin reductase1.8.1.90.442
4b1rITCTetracycline repressor protein class D/0.442
4dpf0LGBeta-secretase 13.4.23.460.442
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.442
4ly91YYGlucokinase regulatory protein/0.442
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.442
4y93746Tyrosine-protein kinase/0.442
5d3qGDPDynamin-13.6.5.50.442
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.442
1bdmNAXMalate dehydrogenase/0.441
1cjkFOKAdenylate cyclase type 2/0.441
1cjkFOKAdenylate cyclase type 5/0.441
1cjtFOKAdenylate cyclase type 2/0.441
1cjtFOKAdenylate cyclase type 5/0.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1ja0FADNADPH--cytochrome P450 reductase/0.441
1jpaANPEphrin type-B receptor 22.7.10.10.441
1kfcIPLTryptophan synthase alpha chain/0.441
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.441
1nvtNAPShikimate dehydrogenase (NADP(+))/0.441
1pg3PRXAcetyl-coenzyme A synthetase/0.441
2ab8MTPAdenosine kinase2.7.1.200.441
2breKJ2ATP-dependent molecular chaperone HSP82/0.441
2dvlFADAcyl-CoA dehydrogenase/0.441
2gtbAZPOrf1ab polyprotein/0.441
2wb2FADRE11660p/0.441
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3gviADPMalate dehydrogenase/0.441
3h3qH13Collagen type IV alpha-3-binding protein/0.441
3p62FMNPentaerythritol tetranitrate reductase/0.441
3vsxR32Renin3.4.23.150.441
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.441
4bfxZVXPantothenate kinase2.7.1.330.441
4bqjXKLHeat shock protein HSP 90-alpha/0.441
4eb5PLPCysteine desulfurase IscS 2/0.441
4gl4NAIAlcohol dehydrogenase class-3/0.441
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.441
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.441
4xguADPPutative pachytene checkpoint protein 2/0.441
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.441
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.441
1a72PADAlcohol dehydrogenase E chain1.1.1.10.440
1qr6NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.440
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.440
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.440
2a92NAIL-lactate dehydrogenase/0.440
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.440
2cy0NAPShikimate dehydrogenase (NADP(+))/0.440
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.440
2fy4COACholine O-acetyltransferase2.3.1.60.440
2g1o2IGRenin3.4.23.150.440
2qf2GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.440
2w0dCGSMacrophage metalloelastase3.4.24.650.440
2yk2YJWHeat shock protein HSP 90-alpha/0.440
3d0bSNXHeat shock protein HSP 90-alpha/0.440
3k8q22APurine nucleoside phosphorylase2.4.2.10.440
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.440
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
3sp9IL2Peroxisome proliferator-activated receptor delta/0.440
3stv3HOMethylketone synthase I/0.440
3tbaADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.440
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
4bfvZVVPantothenate kinase2.7.1.330.440
4df2FMNNADPH dehydrogenase/0.440
4ejvLCLTranscriptional regulator TcaR/0.440
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
4fxy0W2Neurolysin, mitochondrial3.4.24.160.440
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4i8vBHFCytochrome P450 1A11.14.14.10.440
4k6fNAPPutative Acetoacetyl-CoA reductase/0.440
4oqyNDP(S)-imine reductase/0.440
4u7wNDPMxaA/0.440
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.440