sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4fll | YZ6 | Methionine aminopeptidase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 1.000 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.788 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.762 | |
| 4fli | Y16 | Methionine aminopeptidase 1 | / | 0.685 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.678 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.659 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.654 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.648 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.646 | |
| 4ikr | PVP | Methionine aminopeptidase 1 | / | 0.640 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.633 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.615 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.613 | |
| 4iku | SHX | Methionine aminopeptidase 1 | / | 0.604 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.598 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.597 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.597 | |
| 4hxx | 1AY | Methionine aminopeptidase 1 | / | 0.594 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.594 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.592 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.586 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.584 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.580 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.579 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.566 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.565 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.564 | |
| 3pkc | Y08 | Methionine aminopeptidase 2 | / | 0.562 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.558 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.552 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.551 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.547 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.538 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.534 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.534 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.534 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.532 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.531 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.531 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.526 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.524 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.523 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.523 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.517 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.513 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.506 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.506 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.504 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.503 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.500 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.500 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.494 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.493 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.492 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.492 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.490 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.487 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.484 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.484 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.483 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.482 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.481 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 4kxj | P34 | Nucleoprotein | / | 0.479 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.478 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.478 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.478 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.477 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.476 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.476 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.476 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.475 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.475 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2idv | M7G | Eukaryotic translation initiation factor 4E-1 | / | 0.475 | |
| 3c1o | NAP | Eugenol synthase | / | 0.475 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 3e6e | DCS | Alanine racemase | / | 0.475 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.475 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.474 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.474 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.473 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.472 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.472 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.472 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.472 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.470 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.469 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.469 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.469 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.468 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.467 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.466 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.465 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.464 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.464 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.464 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.464 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.462 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.461 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.461 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3zpq | XF5 | Beta-1 adrenergic receptor | / | 0.460 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.460 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.459 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.459 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1swg | BTN | Streptavidin | / | 0.459 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.459 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.459 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.459 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.459 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.459 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.458 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.458 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.458 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.458 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.458 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4e2y | JHZ | Methyltransferase | / | 0.457 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.457 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.457 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.456 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1jf0 | CZH | Obelin | / | 0.456 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.456 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.456 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.456 | |
| 2y01 | Y00 | Beta-1 adrenergic receptor | / | 0.456 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.455 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.455 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.455 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4jic | FMN | GTN Reductase | / | 0.455 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.454 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.454 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.454 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.454 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.454 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.453 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.453 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.453 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.452 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.452 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.452 | |
| 2z4w | 749 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.452 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.452 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.452 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.452 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.451 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.451 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.451 | |
| 3pzc | GAP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.451 | |
| 4gtr | 7TR | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.451 | |
| 1ndi | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.450 | |
| 1s07 | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.450 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.450 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.450 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.450 | |
| 4aza | MGO | Eukaryotic translation initiation factor 4E | / | 0.450 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.450 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.449 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.449 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.449 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.449 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.449 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.449 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.449 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.448 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.448 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.448 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.448 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.447 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.447 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.447 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.447 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.447 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.447 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.447 | |
| 1qs2 | NAD | Vip2Ac | / | 0.446 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 0.446 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.446 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.446 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.446 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.446 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.446 | |
| 2gms | P0P | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.445 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.445 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.445 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.445 | |
| 3ny9 | JSZ | Beta-2 adrenergic receptor | / | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.444 | |
| 4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.444 | |
| 5ief | NBV | Neutral alpha-glucosidase AB | 3.2.1.84 | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.443 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.443 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.443 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.442 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.442 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 3v2u | ATP | Protein GAL3 | / | 0.442 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.442 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.442 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1jf2 | CZH | Obelin | / | 0.441 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2bxq | IMN | Serum albumin | / | 0.441 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.441 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.441 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.441 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 4bqt | C5E | Soluble acetylcholine receptor | / | 0.441 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.441 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.440 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.440 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.440 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.440 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.440 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.440 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.440 | |
| 4gv8 | DUP | DUTPase | / | 0.440 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.440 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.440 |