Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.41.000
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.732
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.660
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.656
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.630
2pwsIBPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.617
3fo7IMNPhospholipase A2 VRV-PL-VIIIa/0.616
1skgVAL_ALA_PHE_ARG_SERBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.611
2othNIMBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.606
4eixNIMPhospholipase A2 VRV-PL-VIIIa/0.587
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.584
1db56INPhospholipase A2, membrane associated/0.555
2qvdBERBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.548
1dcyI3NPhospholipase A2, membrane associated/0.547
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.546
1db48INPhospholipase A2, membrane associated/0.540
3u8dU8DPhospholipase A2, membrane associated/0.533
1kquBR4Phospholipase A2, membrane associated/0.527
2qhwPZZBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.523
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.518
4qf7C0RPhospholipase A2 VRV-PL-VIIIa/0.515
4a8v2ANMajor pollen allergen Bet v 1-J/0.513
1aypINBPhospholipase A2, membrane associated/0.510
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.510
1ndzFR5Adenosine deaminase3.5.4.40.508
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.506
1v79FR7Adenosine deaminase3.5.4.40.505
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.503
1cqp803Integrin alpha-L/0.499
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.499
1umlFR4Adenosine deaminase3.5.4.40.495
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.495
4qa0SHHHistone deacetylase 83.5.1.980.495
1v7aFRCAdenosine deaminase3.5.4.40.494
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.494
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.491
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.490
2xlrFADPutative flavin-containing monooxygenase/0.490
3njuANNAcidic phospholipase A2 33.1.1.40.488
4othDRNSerine/threonine-protein kinase N1/0.488
1qxlFR8Adenosine deaminase3.5.4.40.487
1wxyFRKAdenosine deaminase3.5.4.40.486
4ewqMWLMitogen-activated protein kinase 14/0.486
1o5rFR9Adenosine deaminase3.5.4.40.484
3zxzKRWHepatocyte growth factor receptor2.7.10.10.484
4qa2SHHHistone deacetylase 83.5.1.980.484
2cdaNAPGlucose 1-dehydrogenase/0.481
4qgdPZZPhospholipase A2 VRV-PL-VIIIa/0.481
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.480
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.479
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.479
1x2hLPALipoate-protein ligase A6.3.1.200.478
1y4lSVRBasic phospholipase A2 homolog 2/0.478
2pauD5M5'-deoxynucleotidase YfbR/0.477
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.477
1ao05GPAmidophosphoribosyltransferase/0.476
2jedLG8Protein kinase C theta type2.7.11.130.476
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.476
2hamC33Vitamin D3 receptor/0.475
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.475
3new3NEMitogen-activated protein kinase 14/0.475
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.475
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.475
1fm4DXCMajor pollen allergen Bet v 1-L/0.474
1thnADPAnti-sigma F factor/0.474
2bn4FADNADPH--cytochrome P450 reductase/0.474
4cukNAID-lactate dehydrogenase/0.474
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.473
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.472
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.472
3u8hBHPPhospholipase A2, membrane associated/0.471
4mleVO1Glucokinase2.7.1.20.471
1ove358Mitogen-activated protein kinase 14/0.470
1rfuADPPyridoxal kinase2.7.1.350.470
4a802ANMajor pollen allergen Bet v 1-A/0.470
4a86H35Major pollen allergen Bet v 1-A/0.470
1lhvNOGSex hormone-binding globulin/0.469
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
3iw4LW4Protein kinase C alpha type2.7.11.130.469
4k9yK9YFocal adhesion kinase 12.7.10.20.469
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.469
1ykdCMPAdenylate cyclase/0.468
2j0vGDPRac-like GTP-binding protein ARAC7/0.468
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.468
3owsEQUSteroid Delta-isomerase5.3.3.10.468
4dc0NDPPutative ketoacyl reductase1.3.10.468
1d2sDHTSex hormone-binding globulin/0.467
1kkq471Peroxisome proliferator-activated receptor alpha/0.467
1orhSAHProtein arginine N-methyltransferase 1/0.467
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.467
3ix8TX3Transcriptional activator protein LasR/0.467
3vt7VDXVitamin D3 receptor/0.467
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.466
4fgj1PQRibosyldihydronicotinamide dehydrogenase [quinone]/0.466
4isg1FYGlucokinase2.7.1.20.466
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.466
2hw2RFPRifampin ADP-ribosyl transferase/0.465
3gwfNAPCyclohexanone monooxygenase/0.465
3k47D09Dihydrofolate reductase1.5.1.30.465
3pe2E1BCasein kinase II subunit alpha2.7.11.10.465
4qa1B3NHistone deacetylase 83.5.1.980.465
4rslFADFructosyl peptide oxidase/0.465
2bgiFADNADPH:ferredoxin reductase/0.464
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.464
2vww7X2Ephrin type-B receptor 42.7.10.10.464
3gc9B45Mitogen-activated protein kinase 112.7.11.240.464
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.464
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.463
3h4vDVPPteridine reductase 11.5.1.330.463
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.463
4a84DXCMajor pollen allergen Bet v 1-A/0.463
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.463
5c8d5ADProbable transcriptional regulator/0.463
1zeoC01Peroxisome proliferator-activated receptor gamma/0.462
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.462
2cig1DGDihydrofolate reductase1.5.1.30.462
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.462
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.462
3wznBTNStreptavidin/0.462
4aoxFADSteroid monooxygenase/0.462
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.462
2vf0F89Thymidylate synthase/0.461
2z4y252Geranylgeranyl pyrophosphate synthase/0.461
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.461
3nxvD2FDihydrofolate reductase1.5.1.30.461
4qmySTUSerine/threonine-protein kinase 242.7.11.10.461
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.460
2acwUPGGlycosyltransferase/0.460
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.460
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.460
2rhrEMOPutative ketoacyl reductase1.3.10.460
3dauMTXDihydrofolate reductase1.5.1.30.460
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.460
3nr4PYVAbscisic acid receptor PYL2/0.460
3vf80JETyrosine-protein kinase SYK2.7.10.20.460
4ea2RWZDehydrosqualene synthase/0.460
4fi1ATPCasein kinase II subunit alpha2.7.11.10.460
4nmcFADBifunctional protein PutA/0.460
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.459
3hk1B64Fatty acid-binding protein, adipocyte/0.459
3jziJZLBiotin carboxylase6.3.4.140.459
3ns2PYVAbscisic acid receptor PYL2/0.459
3owuEQUSteroid Delta-isomerase5.3.3.10.459
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
4ea13RXDehydrosqualene synthase/0.459
4gg70J8Hepatocyte growth factor receptor2.7.10.10.459
4klaCHDFerrochelatase, mitochondrial4.99.1.10.459
2xtbKRMAdenosine kinase, putative/0.458
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.458
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.458
3qakUKAAdenosine receptor A2a/0.458
1kl2FONSerine hydroxymethyltransferase/0.457
1kzuRG1Light-harvesting protein B-800/850 alpha chain/0.457
1kzuRG1Light-harvesting protein B-800/850 beta chain/0.457
1t7o152Carnitine O-acetyltransferase2.3.1.70.457
1trkTPPTransketolase 12.2.1.10.457
2hb8MVDVitamin D3 receptor/0.457
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
3nhrRZWRibosyldihydronicotinamide dehydrogenase [quinone]/0.457
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.457
4cnkFADL-amino acid oxidase/0.457
4l17DNQGlutamate receptor 2/0.457
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.457
5c8a5ADProbable transcriptional regulator/0.457
1ia1TQ3Dihydrofolate reductase1.5.1.30.456
2rtoIMIStreptavidin/0.456
3f03FMNPentaerythritol tetranitrate reductase/0.456
3mb714ICasein kinase II subunit alpha2.7.11.10.456
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.456
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.456
4ap1NAPSteroid monooxygenase/0.456
4ax8ADPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.456
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.456
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.456
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.456
4olfHFGProline--tRNA ligase6.1.1.150.456
1cqsEQUSteroid Delta-isomerase5.3.3.10.455
1h51FMNPentaerythritol tetranitrate reductase/0.455
1xddAAYIntegrin alpha-L/0.455
2i40BLZCyclin-dependent kinase 22.7.11.220.455
3c3xNAPEugenol synthase 11.1.1.3180.455
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3iptEQUSteroid Delta-isomerase5.3.3.10.455
3kpzZNEVitamin D3 receptor/0.455
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.455
3oafOAGDihydrofolate reductase1.5.1.30.455
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.455
3tm5SFGUncharacterized protein/0.455
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.455
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.455
4f6vZYMDehydrosqualene synthase/0.455
1m52P17Tyrosine-protein kinase ABL12.7.10.20.454
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.454
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.454
2j9gANPBiotin carboxylase6.3.4.140.454
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.454
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.454
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.454
3b7dCNIGlutamate receptor 2/0.454
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.454
3wsbRWZFarnesyltransferase, putative/0.454
4dliIRGMitogen-activated protein kinase 14/0.454
4g67SAHUncharacterized ACR, COG1565 superfamily/0.454
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
1ndyFR3Adenosine deaminase3.5.4.40.453
1pjkANPCasein kinase II subunit alpha2.7.11.10.453
2bfpH4BPteridine reductase 11.5.1.330.453
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.453
2q4wFADCytokinin dehydrogenase 71.5.99.120.453
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.453
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.453
3ielU5PRibonuclease TTHA02523.10.453
3oapREARetinoic acid receptor RXR-alpha/0.453
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.453
3sl2ATPSensor histidine kinase WalK/0.453
3vt8YI3Vitamin D3 receptor/0.453
4h9506UDihydrofolate reductase1.5.1.30.453
4kwi1TJReductase homolog/0.453
1e92HBIPteridine reductase 11.5.1.330.452
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.452
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.452
2chlDKICasein kinase I isoform gamma-32.7.11.10.452
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
2zjmF1MBeta-secretase 13.4.23.460.452
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.452
3hllI45Mitogen-activated protein kinase 14/0.452
3htjETEbrA repressor/0.452
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.452
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
3uxyNADShort-chain dehydrogenase/reductase SDR/0.452
4bb3KKAIsopenicillin N synthase1.21.3.10.452
4ia3BIVVitamin D3 receptor A/0.452
4jhz1KVBeta-glucuronidase3.2.1.310.452
4nbb9CATerminal oxygenase component of carbazole/0.452
4xz3COAAcyl-CoA synthetase (NDP forming)/0.452
3uzaT4GAdenosine receptor A2a/0.452
1ay0TPPTransketolase 12.2.1.10.451
3c3eFO12-phospho-L-lactate transferase/0.451
3elm24FCollagenase 33.4.240.451
4zvnFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.451
4s0vSUVOrexin receptor type 2/0.451
1xuzMMNCapsule biosynthesis protein/0.450
2vnjFADNADPH:ferredoxin reductase/0.450
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.450
2xvw9NRSerum albumin/0.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3pd4A3GThreonine--tRNA ligase6.1.1.30.450
4b1fKRHGlutamate racemase/0.450
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.450
4gg50J3Hepatocyte growth factor receptor2.7.10.10.450
4hnf16WCasein kinase I isoform delta2.7.11.10.450
4jlt8PRCytochrome P450 2B41.14.14.10.450
4jucTPPBenzoylformate decarboxylase4.1.1.70.450
4k7yFMNNADPH dehydrogenase 11.6.99.10.450
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.450
5cvhADPCasein kinase II subunit alpha2.7.11.10.450
1cjkFOKAdenylate cyclase type 2/0.449
1cjkFOKAdenylate cyclase type 5/0.449
1fkwPURAdenosine deaminase3.5.4.40.449
1srfMTBStreptavidin/0.449
1tl7FOKAdenylate cyclase type 2/0.449
1tl7FOKAdenylate cyclase type 5/0.449
2cduADPNADH oxidase/0.449
2izrBRKCasein kinase I isoform gamma-32.7.11.10.449
2izuP01Casein kinase I isoform gamma-32.7.11.10.449
2po7CHDFerrochelatase, mitochondrial4.99.1.10.449
2z2w770Wee1-like protein kinase2.7.10.20.449
3ahiHTLProbable phosphoketolase/0.449
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.449
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.449
3pd2A3SThreonine--tRNA ligase6.1.1.30.449
3rthRTHBeta-secretase 13.4.23.460.449
3s41S41Glucokinase2.7.1.20.449
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.449
3tm4SAMUncharacterized protein/0.449
4bchT7ZCyclin-dependent kinase 92.7.11.220.449
4fvz4KJNitric oxide synthase, brain1.14.13.390.449
4relKMPGlycosyltransferase/0.449
4xwtU5PRibonuclease J/0.449
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.448
2e95B75Geranylgeranyl pyrophosphate synthase/0.448
2ociTYCValacyclovir hydrolase3.10.448
2w3mFOLDihydrofolate reductase1.5.1.30.448
2xvv9DNSerum albumin/0.448
3bejMUFBile acid receptor/0.448
3o9lLPNRenin3.4.23.150.448
4cd2FOLDihydrofolate reductase1.5.1.30.448
4g48PZBMycocyclosin synthase1.14.21.90.448
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.448
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.448
1m2rMNYCasein kinase II subunit alpha2.7.11.10.447
1nq7ARLNuclear receptor ROR-beta/0.447
1sj0E4DEstrogen receptor/0.447
1swtBTNStreptavidin/0.447
1y56FMNUncharacterized protein/0.447
1y56FMN382aa long hypothetical sarcosine oxidase/0.447
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.447
2j5sKTAAlr4455 protein/0.447
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
2zbaZBATrichothecene 3-O-acetyltransferase/0.447
2zevIPEGeranylgeranyl pyrophosphate synthase/0.447
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.447
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.447
4fod0UVALK tyrosine kinase receptor2.7.10.10.447
4hni16WCasein kinase I isoform epsilon2.7.11.10.447
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.447
4ips1G4Mycocyclosin synthase1.14.21.90.447
4kak06UDihydrofolate reductase1.5.1.30.447
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.447
4looSB4Mitogen-activated protein kinase 14/0.447
1dz8CAMCamphor 5-monooxygenase1.14.15.10.446
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.446
1v35NAIEnoyl-ACP reductase/0.446
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.446
2ed3SAHDiphthine synthase/0.446
2vagV25Dual specificity protein kinase CLK12.7.12.10.446
3acy702Dehydrosqualene synthase/0.446
3ldfSAHUncharacterized protein/0.446
3n63XFNNitric oxide synthase, brain1.14.13.390.446
3oom507Activin receptor type-12.7.11.300.446
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.446
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4xymCOAAcyl-CoA synthetase (NDP forming)/0.446
5bp9SAHPutative methyltransferase protein/0.446
3emlZMAAdenosine receptor A2a/0.446
1h50FMNPentaerythritol tetranitrate reductase/0.445
1iiuRTLRetinol-binding protein 4/0.445
1kt6RTLRetinol-binding protein 4/0.445
1lf3EH5Plasmepsin-23.4.23.390.445
1oi9N20Cyclin-dependent kinase 22.7.11.220.445
1p33MTXPteridine reductase 11.5.1.330.445
1rx8FOLDihydrofolate reductase1.5.1.30.445
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.445
2hxzH7JCathepsin S3.4.22.270.445
2rtkGLLStreptavidin/0.445
2vz0D64Pteridine reductase/0.445
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.445
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.445
3inwJZBHeat shock protein HSP 90-alpha/0.445
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.445
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.445
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.445
3pd3A3TThreonine--tRNA ligase6.1.1.30.445
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.445
4eevL1XHepatocyte growth factor receptor2.7.10.10.445
4h9614QDihydrofolate reductase1.5.1.30.445
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.445
4ise1FWGlucokinase2.7.1.20.445
4jr7GNPCasein kinase II subunit alpha2.7.11.10.445
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
1mdrAPGMandelate racemase/0.444
1ohoEQUSteroid Delta-isomerase5.3.3.10.444
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.444
1tilATPAnti-sigma F factor/0.444
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2abbFMNPentaerythritol tetranitrate reductase/0.444
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.444
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.444
2tscCB3Thymidylate synthase/0.444
2w3aTOPDihydrofolate reductase1.5.1.30.444
2w3wVG9Dihydrofolate reductase/0.444
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
3l0lHC3Nuclear receptor ROR-gamma/0.444
3pdqKC6Lysine-specific demethylase 4A1.14.110.444
3zze6XPHepatocyte growth factor receptor2.7.10.10.444
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4g090VDHistidinol dehydrogenase/0.444
4g170VNCasein kinase I isoform gamma-32.7.11.10.444
4mryCEIObelin/0.444
5d7pAR6NAD-dependent protein deacetylase sirtuin-23.5.10.444
1fkxPRHAdenosine deaminase3.5.4.40.443
1nzdUPGDNA beta-glucosyltransferase/0.443
1o2eANNPhospholipase A23.1.1.40.443
1ogxEQUSteroid Delta-isomerase5.3.3.10.443
1opbRETRetinol-binding protein 2/0.443
1qiwDPDCalmodulin/0.443
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.443
1xi2CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
2hbhXE4Vitamin D3 receptor A/0.443
2in6839Wee1-like protein kinase2.7.10.20.443
2kceD16Thymidylate synthase/0.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.443
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.443
3c3eGDP2-phospho-L-lactate transferase/0.443
3ibqATPPyridoxal kinase/0.443
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.443
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
3pqbVGPPutative oxidoreductase/0.443
3q30D61Squalene synthase2.5.1.210.443
3vtdTKDVitamin D3 receptor/0.443
3zg6APRNAD-dependent protein deacetylase sirtuin-63.5.10.443
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.443
4bjx73BBromodomain-containing protein 4/0.443
4c67L5SBromodomain-containing protein 4/0.443
4eh9IRGMitogen-activated protein kinase 14/0.443
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4gmy0X5Tyrosine-protein kinase JAK2/0.443
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.443
4kb81QOCasein kinase I isoform delta2.7.11.10.443
1lb9DNQGlutamate receptor 2/0.442
1luaNAPBifunctional protein MdtA1.5.1.50.442
1x8lOXRRetinol dehydratase/0.442
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
2c475IDCasein kinase I isoform gamma-2/0.442
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.442
2o4jVD4Vitamin D3 receptor/0.442
2qd5CHDFerrochelatase, mitochondrial4.99.1.10.442
2r2mI50Prothrombin3.4.21.50.442
2vmyFFOSerine hydroxymethyltransferase/0.442
2yeiXQIHeat shock protein HSP 90-alpha/0.442
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.442
3mjrAC2Deoxycytidine kinase2.7.1.740.442
3nga3NGCasein kinase II subunit alpha2.7.11.10.442
3stv3HOMethylketone synthase I/0.442
3vufADPGranule-bound starch synthase 1, chloroplastic/amyloplastic2.4.1.2420.442
3w5tLHPVitamin D3 receptor/0.442
3zw9T1GPeroxisomal bifunctional enzyme1.1.1.350.442
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4deg0JJHepatocyte growth factor receptor2.7.10.10.442
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4i9i1DYTankyrase-12.4.2.300.442
4kip1R9Mitogen-activated protein kinase 14/0.442
4men25KBromodomain-containing protein 4/0.442
4mwhATPCasein kinase II subunit alpha2.7.11.10.442
4nqmY1ZBromodomain-containing protein 4/0.442
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1dkfBMSRetinoic acid receptor alpha/0.441
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1nq04HYThyroid hormone receptor beta/0.441
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2b35TCLEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2v19FMNDodecin/0.441
2w3vTOPDihydrofolate reductase/0.441
2wcgMT5Glucosylceramidase3.2.1.450.441
3a4pDFQHepatocyte growth factor receptor2.7.10.10.441
3blrCPBCyclin-dependent kinase 92.7.11.220.441
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.441
3fwfCAMCamphor 5-monooxygenase1.14.15.10.441
3p74FMNPentaerythritol tetranitrate reductase/0.441
3q5kD1UHeat shock protein 83-1/0.441
3tfp03LDehydrosqualene synthase/0.441
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
3zeiAWHO-acetylserine sulfhydrylase/0.441
4blwSAHRibosomal RNA large subunit methyltransferase J/0.441
4c02TAKActivin receptor type-12.7.11.300.441
4c717RD3-oxoacyl-ACP synthase/0.441
4fkg4CKCyclin-dependent kinase 22.7.11.220.441
4g47TZFMycocyclosin synthase1.14.21.90.441
4isf1FXGlucokinase2.7.1.20.441
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.441
4mlhVO2Glucokinase2.7.1.20.441
4nbwNADShort-chain dehydrogenase/reductase SDR/0.441
4nc3ERM5-hydroxytryptamine receptor 2B/0.441
4pkwGM6Lethal factor3.4.24.830.441
4twnB96Ephrin type-A receptor 32.7.10.10.441
4zhiADPKinesin-like protein KIF11/0.441
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.441
5e8wSTUTGF-beta receptor type-12.7.11.300.441
5jjrSAHGenome polyprotein/0.441
5k8bPDG8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase/0.441
4k5y1Q5Corticotropin-releasing factor receptor 1/0.441
1a72PADAlcohol dehydrogenase E chain1.1.1.10.440
1bp0UMPThymidylate synthase/0.440
1e7aPFLSerum albumin/0.440
1f28UMPThymidylate synthase2.1.1.450.440
1qipGNBLactoylglutathione lyase4.4.1.50.440
1tvcFDAMethane monooxygenase component C1.14.13.250.440
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.440
2hcdBIVVitamin D3 receptor A/0.440
2op18PCEnoyl-ACP reductase/0.440
2pz5ACPFibroblast growth factor receptor 2/0.440
2wgjVGHHepatocyte growth factor receptor2.7.10.10.440
2yac937Serine/threonine-protein kinase PLK12.7.11.210.440
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.440
3csdEMOPutative ketoacyl reductase1.3.10.440
3datMTXDihydrofolate reductase/0.440
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.440
3ggfGVDSerine/threonine-protein kinase 26/0.440
3hl7I46Mitogen-activated protein kinase 14/0.440
3ivcFG4Pantothenate synthetase6.3.2.10.440
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3mtlFEFCyclin-dependent kinase 162.7.11.220.440
3oagLPQRenin3.4.23.150.440
3tfn2CJDehydrosqualene synthase/0.440
3tzaTZGGlutamate receptor 2/0.440
3ua506XCytochrome P450 2B61.14.130.440
4aqlTXCGuanine deaminase3.5.4.30.440
4at0FADPossible succinate dehydrogenase/0.440
4at2ASDPossible succinate dehydrogenase/0.440
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
4eerFMNPhototropin-22.7.11.10.440
4g160VMCasein kinase I isoform gamma-32.7.11.10.440
4ia7BIVVitamin D3 receptor A/0.440
4ktkKTKCytochrome P450/0.440
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.440
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4yao2AMNADPH--cytochrome P450 reductase/0.440
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.440
5k2cZMAAdenosine receptor A2a/0.440