sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2igx | A1T | Plasmepsin 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2igx | A1T | Plasmepsin 2 | / | 1.000 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.550 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.540 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.528 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.520 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.514 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.512 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.509 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.508 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.508 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.506 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.505 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.504 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.503 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.500 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.498 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.496 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.496 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.496 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.496 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.495 | |
| 2ynh | EUR | Gag-Pol polyprotein | 2.7.7.49 | 0.495 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.494 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.494 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.492 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.491 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.490 | |
| 2won | ZZE | Gag-Pol polyprotein | 2.7.7.49 | 0.490 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.490 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.490 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.489 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.489 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.488 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.488 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.487 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.486 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.486 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.486 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.486 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.486 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.485 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.485 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.485 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.484 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.484 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.483 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.483 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.483 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.483 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.482 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.482 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.481 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.481 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.481 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.480 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.480 | |
| 3up0 | D7S | aceDAF-12 | / | 0.480 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.479 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.479 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.478 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.478 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.477 | |
| 2ejz | SAH | Diphthine synthase | / | 0.477 | |
| 3drp | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.477 | |
| 3t19 | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.477 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.477 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.477 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.476 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.476 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.476 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.476 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.476 | |
| 3qly | 55V | Uncharacterized protein | / | 0.476 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.476 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.475 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1osv | CHC | Bile acid receptor | / | 0.475 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 3p9k | CIY | Caffeic acid O-methyltransferase | / | 0.475 | |
| 1sqv | UHD | Cytochrome b | / | 0.474 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.474 | |
| 3qcl | NXV | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.474 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.474 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.474 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.474 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.474 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.474 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.474 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.473 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.473 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.473 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.473 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.473 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.473 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.473 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.473 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.473 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.473 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.472 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.472 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.472 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.472 | |
| 4cry | ACO | PanD regulatory factor | / | 0.472 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.472 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.471 | |
| 1pp9 | SMA | Cytochrome b | / | 0.471 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.471 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.470 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.470 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.470 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.470 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3bej | MUF | Bile acid receptor | / | 0.470 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.470 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.470 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.470 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.470 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.470 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.469 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.469 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.469 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.469 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 4rw4 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.468 | |
| 3eej | 53R | Uncharacterized protein | / | 0.468 | |
| 3eem | 53V | Uncharacterized protein | / | 0.468 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.468 | |
| 2fdu | D1G | Cytochrome P450 2A6 | 1.14.13 | 0.467 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2x23 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.467 | |
| 3i68 | J4Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.467 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.467 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 1err | RAL | Estrogen receptor | / | 0.466 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.466 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.466 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
| 3fnu | 006 | HAP protein | / | 0.466 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 3tam | M06 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.466 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 4lsl | 1YQ | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.465 | |
| 1sze | 173 | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.465 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.465 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.465 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.465 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.465 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3eek | 53S | Uncharacterized protein | / | 0.465 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.465 | |
| 3v49 | PK0 | Androgen receptor | / | 0.465 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.465 | |
| 4l4x | NDP | AmphI | / | 0.465 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.465 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.464 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.464 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.464 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.464 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.464 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.464 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 4ap0 | ADP | Kinesin-like protein KIF11 | / | 0.464 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.464 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.464 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.464 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.463 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.463 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.463 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.463 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.463 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.463 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.463 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.463 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.463 | |
| 1e7a | PFL | Serum albumin | / | 0.462 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 2ynf | WHU | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.462 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.462 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.462 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.462 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.462 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.462 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.462 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.462 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 2qjy | SMA | Cytochrome b | / | 0.461 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.461 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.461 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.461 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.461 | |
| 3zqt | TES | Androgen receptor | / | 0.461 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.461 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.461 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.460 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.460 | |
| 3r3c | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.460 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.460 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.460 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.460 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.460 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.460 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.460 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.459 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.459 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.459 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 1zdw | FLV | Prenyltransferase | / | 0.459 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.459 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.459 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 3up3 | XCA | aceDAF-12 | / | 0.459 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.459 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.459 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.458 | |
| 3fmz | 2T1 | Retinol-binding protein 4 | / | 0.458 | |
| 3fzs | B96 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.458 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.458 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.458 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.458 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.458 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.457 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.457 | |
| 1q4x | G24 | Thyroid hormone receptor beta | / | 0.457 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.457 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.457 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.457 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.457 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.457 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.457 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.457 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.457 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.456 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3p9t | TCL | Repressor | / | 0.456 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.456 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.455 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.455 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.455 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.455 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.455 | |
| 3b9l | AZZ | Serum albumin | / | 0.455 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.455 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4ztv | TA7 | Anthranilate phosphoribosyltransferase | / | 0.455 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.455 | |
| 1jut | LYD | Thymidylate synthase | / | 0.454 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.454 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.454 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.454 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.454 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.454 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.454 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.454 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1eio | GCH | Gastrotropin | / | 0.453 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.453 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.453 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 1kyo | SMA | Cytochrome b | / | 0.453 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1s36 | CEI | Obelin | / | 0.453 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.453 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.453 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.453 | |
| 3dok | GWJ | Pol protein | / | 0.453 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.453 | |
| 3l70 | JZV | Cytochrome b | / | 0.453 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.453 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.453 | |
| 4okt | 198 | Androgen receptor | / | 0.453 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.452 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.452 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.452 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.452 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.452 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.452 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.452 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.452 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.452 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.452 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.451 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.451 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.451 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.451 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.451 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.451 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.451 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.451 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.451 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.451 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.451 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.451 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.451 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 5l7d | CLR | Smoothened homolog | / | 0.451 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.450 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.450 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.450 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.450 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.450 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 2xdr | NDP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.450 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.450 | |
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.450 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.450 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.450 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.450 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.450 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.450 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.450 | |
| 4zas | TYD | CalS13 | / | 0.450 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.450 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.449 | |
| 1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.449 | |
| 1wc0 | APC | Adenylate cyclase | / | 0.449 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.449 | |
| 2acw | UPG | Glycosyltransferase | / | 0.449 | |
| 2e82 | IM3 | D-amino-acid oxidase | 1.4.3.3 | 0.449 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 3aba | FLI | Cytochrome P450 | / | 0.449 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3bhl | THG | Thymidylate synthase | / | 0.449 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3h1j | SMA | Cytochrome b | / | 0.449 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.449 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.449 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.449 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.449 | |
| 4yak | COA | Acyl-CoA synthetase (NDP forming) | / | 0.449 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.449 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.448 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.448 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.448 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.448 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.448 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.448 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.448 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.448 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.448 | |
| 4at9 | UTP | Interleukin enhancer-binding factor 2 | / | 0.448 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.448 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4fox | D16 | Thymidylate synthase ThyA | / | 0.448 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.448 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.448 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.448 | |
| 4o7u | THF | Thymidylate synthase | / | 0.448 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1fro | GSB | Lactoylglutathione lyase | 4.4.1.5 | 0.447 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.447 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.447 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.447 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.447 | |
| 2cbs | R13 | Cellular retinoic acid-binding protein 2 | / | 0.447 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.447 | |
| 2p15 | EZT | Estrogen receptor | / | 0.447 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.447 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3mcy | ZH1 | FimH | / | 0.447 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.447 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.447 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.447 | |
| 1f28 | F89 | Thymidylate synthase | 2.1.1.45 | 0.446 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.446 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1z7e | UGA | Bifunctional polymyxin resistance protein ArnA | / | 0.446 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.446 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 2ibz | SMA | Cytochrome b | / | 0.446 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.446 | |
| 2pnu | ENM | Androgen receptor | / | 0.446 | |
| 2q5q | KPV | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.446 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.446 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.446 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.446 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.446 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 5doz | NDP | JamJ | / | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 1hnd | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.445 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 2rti | GLL | Streptavidin | / | 0.445 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.445 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.445 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.445 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 4egn | TWO | Cytochrome P450 | / | 0.445 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.445 | |
| 4pl4 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.445 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.444 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.444 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.444 | |
| 2kce | D16 | Thymidylate synthase | / | 0.444 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.444 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.444 | |
| 3cse | N22 | Uncharacterized protein | / | 0.444 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.444 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.444 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3qci | NX3 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.444 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.444 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.444 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.444 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.444 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.444 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.444 | |
| 5kcp | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.444 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1l0l | FMX | Cytochrome b | / | 0.443 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.443 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.443 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.443 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.443 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.443 | |
| 2mm3 | CHO | Gastrotropin | / | 0.443 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.443 | |
| 3qck | NX5 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.443 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.443 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.443 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.443 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.443 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.443 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.442 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.442 | |
| 1syn | F89 | Thymidylate synthase | / | 0.442 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.442 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.442 | |
| 2ako | ADP | Glutamate 5-kinase | / | 0.442 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2lzg | 13Q | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.442 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.442 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.442 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.442 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.442 | |
| 3il6 | B83 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.442 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.442 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.442 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.442 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.442 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.441 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.441 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.441 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.441 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.441 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.441 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.441 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.441 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.441 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.441 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.441 | |
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.441 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.441 | |
| 4b1f | KRH | Glutamate racemase | / | 0.441 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4hur | ACO | Virginiamycin A acetyltransferase | 2.3.1 | 0.441 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 2j07 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.440 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 2xls | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.440 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.440 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.440 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.440 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.440 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.440 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.440 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.440 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |