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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.11.000
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.742
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.632
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.532
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.525
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.521
4gyiADPUncharacterized protein/0.520
4c4f7CEDual specificity protein kinase TTK2.7.12.10.516
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.516
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.515
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.515
5cvfATPCasein kinase II subunit alpha2.7.11.10.512
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.511
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.511
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.511
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.510
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.510
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.508
3q9xEMOCasein kinase II subunit alpha2.7.11.10.508
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.507
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.505
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.503
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.501
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.501
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.501
3at4CCKCasein kinase II subunit alpha2.7.11.10.500
2ijmADPFocal adhesion kinase 12.7.10.20.499
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.495
3bqr4RBDeath-associated protein kinase 3/0.494
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.494
5auvAGIDeath-associated protein kinase 12.7.11.10.493
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.492
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.492
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.492
5auwQUEDeath-associated protein kinase 12.7.11.10.492
3gubGUBDeath-associated protein kinase 12.7.11.10.491
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.489
3s2pPMUCyclin-dependent kinase 22.7.11.220.489
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
1unlRRCCyclin-dependent-like kinase 52.7.11.10.487
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.487
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.487
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
3pe2E1BCasein kinase II subunit alpha2.7.11.10.486
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.485
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.485
5av2KMPDeath-associated protein kinase 12.7.11.10.485
1pjkANPCasein kinase II subunit alpha2.7.11.10.484
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.484
3sheI85MAP kinase-activated protein kinase 32.7.11.10.484
3uyt0CKCasein kinase I isoform delta2.7.11.10.483
4dgnLU2Casein kinase II subunit alpha2.7.11.10.483
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.483
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.482
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.481
3axwTIDCasein kinase II subunit alpha2.7.11.10.481
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.481
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.480
4dgmAGICasein kinase II subunit alpha2.7.11.10.480
4q5hANPProtein kinase OspG2.70.480
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
3qyw6PBMitogen-activated protein kinase 12.7.11.240.479
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.479
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.479
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.478
2btsU32Cyclin-dependent kinase 22.7.11.220.478
2pvnP63Casein kinase II subunit alpha2.7.11.10.478
3nwxKVSGag-Pol polyprotein3.4.23.160.478
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.478
2j0lANPFocal adhesion kinase 12.7.10.20.477
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.477
4grb0XGCasein kinase II subunit alpha2.7.11.10.477
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.476
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.476
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.476
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.476
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.476
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.475
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.475
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.475
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.475
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
2hog710Serine/threonine-protein kinase Chk12.7.11.10.474
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.474
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.474
2cchATPCyclin-dependent kinase 22.7.11.220.473
2ijmATPFocal adhesion kinase 12.7.10.20.473
2zjwREFCasein kinase II subunit alpha2.7.11.10.473
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.472
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.472
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
5av3KMPDeath-associated protein kinase 12.7.11.10.472
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.471
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3qaiXNNKetohexokinase/0.471
4c4iX20Dual specificity protein kinase TTK2.7.12.10.471
4fod0UVALK tyrosine kinase receptor2.7.10.10.471
1wvxBD4Death-associated protein kinase 12.7.11.10.470
2y9qANPMitogen-activated protein kinase 12.7.11.240.470
3be9P04Casein kinase II subunit alpha2.7.11.10.470
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.470
4ix6ADPUncharacterized protein/0.470
1tvoFRZMitogen-activated protein kinase 12.7.11.240.469
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.469
3cgfJNFMitogen-activated protein kinase 102.7.11.240.469
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.469
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.469
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
4fv8E63Mitogen-activated protein kinase 12.7.11.240.468
4fv9E71Mitogen-activated protein kinase 12.7.11.240.468
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.468
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.467
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.467
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3nynSGVG protein-coupled receptor kinase 62.7.11.160.467
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.467
4fmqANPMitogen-activated protein kinase 12.7.11.240.467
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.467
1me8RVPInosine-5'-monophosphate dehydrogenase/0.466
3kvxFMYMitogen-activated protein kinase 102.7.11.240.466
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.466
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.465
1om1IQACasein kinase II subunit alpha2.7.11.10.465
2iw84SPCyclin-dependent kinase 22.7.11.220.465
3aidARQGag-Pol polyprotein3.4.23.160.465
3cwkREACellular retinoic acid-binding protein 2/0.465
3umw596Serine/threonine-protein kinase pim-12.7.11.10.465
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4i22IREEpidermal growth factor receptor2.7.10.10.465
1eh4IC1Casein kinase I homolog 12.7.11.10.464
2etm7PYFocal adhesion kinase 12.7.10.20.464
2w17I19Cyclin-dependent kinase 22.7.11.220.464
3dfcANPDeath-associated protein kinase 12.7.11.10.464
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.464
4ocvANPAminoglycoside phosphotransferase/0.464
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.463
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.463
3nux3NVCyclin-dependent kinase 62.7.11.220.463
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
4g3pUD1Bifunctional protein GlmU/0.463
4k8aK8AFocal adhesion kinase 12.7.10.20.463
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.462
2vu3LZECyclin-dependent kinase 22.7.11.220.462
3bheBZNGag-Pol polyprotein3.4.23.160.462
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.462
3tucFPWTyrosine-protein kinase SYK2.7.10.20.462
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4a6bQG8Gag-Pol polyprotein3.4.23.160.462
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.462
4kbk1QGCasein kinase I isoform delta2.7.11.10.462
5k2dZMAAdenosine receptor A2a/0.462
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
1ckpPVBCyclin-dependent kinase 22.7.11.220.461
1cqp803Integrin alpha-L/0.461
1xjdSTUProtein kinase C theta type2.7.11.130.461
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.461
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.461
3nbvANPKetohexokinase/0.461
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.461
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.460
2xrwANPMitogen-activated protein kinase 82.7.11.240.460
3i0rRT3Gag-Pol polyprotein2.7.7.490.460
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.459
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.459
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.459
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.459
5dr9SKEAurora kinase A2.7.11.10.459
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.458
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.458
3cgoJNOMitogen-activated protein kinase 102.7.11.240.458
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.458
3nieANPMitogen-activated protein kinase/0.458
3qxoX65Cyclin-dependent kinase 22.7.11.220.458
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
4btjADPTau-tubulin kinase 12.7.11.10.458
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.458
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.458
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.457
1k6tXN1Gag-Pol polyprotein3.4.23.160.457
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.457
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.457
2bfyH1NAurora kinase B-A2.7.11.10.457
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.457
3iodA6DPantothenate synthetase6.3.2.10.457
3wecAUICytochrome P450/0.457
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
5k2aZMAAdenosine receptor A2a/0.457
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.456
1m2pHNACasein kinase II subunit alpha2.7.11.10.456
2h96893Mitogen-activated protein kinase 82.7.11.240.456
2hcdBIVVitamin D3 receptor A/0.456
2jkqVG8Focal adhesion kinase 12.7.10.20.456
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.456
2pywADPMethylthioribose kinase2.7.1.1000.456
2wotZZGTGF-beta receptor type-12.7.11.300.456
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.456
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.456
4dtaADNAPH(2'')-Id/0.456
4ez50RSCyclin-dependent kinase 62.7.11.220.456
4hnf16WCasein kinase I isoform delta2.7.11.10.456
4j5j478Gag-Pol polyprotein3.4.23.160.456
1fvv107Cyclin-dependent kinase 22.7.11.220.455
2ca0PXICytochrome P450 monooxygenase PikC/0.455
4b7dQLECytochrome P450 monooxygenase PikC/0.455
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4fkpLS5Cyclin-dependent kinase 22.7.11.220.455
4jboWPHAurora kinase A2.7.11.10.455
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.454
2r64740Cyclin-dependent kinase 22.7.11.220.454
2v51LABActin, alpha skeletal muscle/0.454
3chwATPMajor actin/0.454
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3rm618ZCyclin-dependent kinase 22.7.11.220.454
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.454
3vrwYS5Vitamin D3 receptor/0.454
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4aguD15Cyclin-dependent kinase-like 1/0.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.454
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.454
4y8wSTRSteroid 21-hydroxylase/0.454
4y93746Tyrosine-protein kinase/0.454
5cshATPCasein kinase II subunit alpha2.7.11.10.454
1bygSTUTyrosine-protein kinase CSK/0.453
1e9hINRCyclin-dependent kinase 22.7.11.220.453
2c7xNRBCytochrome P450 monooxygenase PikC/0.453
2iw94SPCyclin-dependent kinase 22.7.11.220.453
2oji33AMitogen-activated protein kinase 12.7.11.240.453
3pxkPXKFocal adhesion kinase 12.7.10.20.453
3qarQARPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.453
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.453
1aq1STUCyclin-dependent kinase 22.7.11.220.452
1bdrIM1Gag-Pol polyprotein3.4.23.160.452
1j39UPGDNA beta-glucosyltransferase/0.452
1rk3VDXVitamin D3 receptor/0.452
1u4dDBQActivated CDC42 kinase 1/0.452
2etrY27Rho-associated protein kinase 12.7.11.10.452
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.452
3b2eADPATPase GET3/0.452
3r1sX73Cyclin-dependent kinase 22.7.11.220.452
3rak03ZCyclin-dependent kinase 22.7.11.220.452
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.452
4g1wG1WMitogen-activated protein kinase 82.7.11.240.452
4ia3BIVVitamin D3 receptor A/0.452
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.452
1k6cMK1Gag-Pol polyprotein3.4.23.160.451
1vyw292Cyclin-dependent kinase 22.7.11.220.451
2a4lRRCCyclin-dependent kinase 22.7.11.220.451
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.451
2duv371Cyclin-dependent kinase 22.7.11.220.451
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.451
3orkAGSSerine/threonine protein kinase/0.451
3orpAGSSerine/threonine protein kinase/0.451
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.451
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.451
4ienCOAPutative acyl-CoA hydrolase/0.451
1h0w207Cyclin-dependent kinase 22.7.11.220.450
1oiyN41Cyclin-dependent kinase 22.7.11.220.450
2ckeIQUDeath-associated protein kinase 2/0.450
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.450
2xngA0HAurora kinase A2.7.11.10.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
3bu5ATPInsulin receptor2.7.10.10.450
3imeBZ2Pantothenate synthetase6.3.2.10.450
3ortAGSSerine/threonine protein kinase/0.450
3t113T1Gag-Pol polyprotein3.4.23.160.450
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.450
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
5ap7SVEDual specificity protein kinase TTK2.7.12.10.450
5av4GENDeath-associated protein kinase 12.7.11.10.450
5cu6ATPCasein kinase II subunit alpha2.7.11.10.450
1osvCHCBile acid receptor/0.449
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2r3gSC9Cyclin-dependent kinase 22.7.11.220.449
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.449
2z97CAMCamphor 5-monooxygenase1.14.15.10.449
2zlcVDXVitamin D3 receptor/0.449
3ddqRRCCyclin-dependent kinase 22.7.11.220.449
3r1yX76Cyclin-dependent kinase 22.7.11.220.449
3zdu38RCyclin-dependent kinase-like 32.7.11.220.449
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4gub0Y4Casein kinase II subunit alpha2.7.11.10.449
4ic7ANPMitogen-activated protein kinase 72.7.11.240.449
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1kzkJE2Gag-Pol polyprotein3.4.23.160.448
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.448
1xl2189Gag-Pol polyprotein3.4.23.160.448
3mb714ICasein kinase II subunit alpha2.7.11.10.448
3vt5YI2Vitamin D3 receptor/0.448
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.448
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.448
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.448
5auzGENDeath-associated protein kinase 12.7.11.10.448
1idb0DOGag-Pol polyprotein/0.447
1me7RVPInosine-5'-monophosphate dehydrogenase/0.447
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.447
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.447
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3dj4UD1Bifunctional protein GlmU/0.447
3sw719KCyclin-dependent kinase 22.7.11.220.447
4anmWULCasein kinase II subunit alpha2.7.11.10.447
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.447
4eok4SPCyclin-dependent kinase 22.7.11.220.447
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.447
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.447
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.447
5jtbZMAAdenosine receptor A2a/0.447
1qbu846Gag-Pol polyprotein3.4.23.160.446
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
2cdaNAPGlucose 1-dehydrogenase/0.446
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.446
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3ezvEZVCyclin-dependent kinase 22.7.11.220.446
3iggEFQCyclin-dependent kinase 22.7.11.220.446
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.446
3w0iO11Vitamin D3 receptor/0.446
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.446
4iarERM5-hydroxytryptamine receptor 1B/0.446
4izy1J2Mitogen-activated protein kinase 82.7.11.240.446
1c70L75Protease/0.445
1pmn984Mitogen-activated protein kinase 102.7.11.240.445
1pxmCK5Cyclin-dependent kinase 22.7.11.220.445
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.445
1xkkFMMEpidermal growth factor receptor2.7.10.10.445
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.445
1zy8FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.445
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.445
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.445
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.445
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.445
2ghmLICMitogen-activated protein kinase 14/0.445
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2xs0ANPMitogen-activated protein kinase 82.7.11.240.445
3pgqGY3Acetyl-CoA carboxylase/0.445
3qruX19Cyclin-dependent kinase 22.7.11.220.445
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.445
4d58BI9Focal adhesion kinase 12.7.10.20.445
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4fkv61KCyclin-dependent kinase 22.7.11.220.445
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.445
5cvhADPCasein kinase II subunit alpha2.7.11.10.445
5k2cZMAAdenosine receptor A2a/0.445
1d4hBEHGag-Pol polyprotein3.4.23.160.444
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2c475IDCasein kinase I isoform gamma-2/0.444
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.444
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.444
3cf0ADPTransitional endoplasmic reticulum ATPase3.6.4.60.444
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.444
3w5rLOAVitamin D3 receptor/0.444
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.444
4b8zNAPGDP-L-fucose synthase1.1.1.2710.444
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.444
4fkg4CKCyclin-dependent kinase 22.7.11.220.444
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.444
4fv6E57Mitogen-activated protein kinase 12.7.11.240.444
4g170VNCasein kinase I isoform gamma-32.7.11.10.444
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.444
4jia1K3Tyrosine-protein kinase JAK2/0.444
4y95746Tyrosine-protein kinase/0.444
1jklANPDeath-associated protein kinase 12.7.11.10.443
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.443
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.443
2btrU73Cyclin-dependent kinase 22.7.11.220.443
2fvdLIACyclin-dependent kinase 22.7.11.220.443
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.443
3nu9478Gag-Pol polyprotein3.4.23.160.443
3te4ACODopamine N-acetyltransferase/0.443
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4dgo0JWCasein kinase II subunit alpha2.7.11.10.443
4eor4SPCyclin-dependent kinase 22.7.11.220.443
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4g3qUD1Bifunctional protein GlmU/0.443
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.443
4n6bCOAUncharacterized protein/0.443
4qmzB49Serine/threonine-protein kinase 242.7.11.10.443
4uyf73BBromodomain-containing protein 2/0.443
4wluNADMalate dehydrogenase, mitochondrial1.1.1.370.443
4xgxADPFAD:protein FMN transferase/0.443
5da9AGSUncharacterized protein/0.443
5k2bZMAAdenosine receptor A2a/0.443
1gii1PUCyclin-dependent kinase 22.7.11.220.442
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.442
1sn5T3Transthyretin/0.442
1v0pPVBCell division control protein 2 homolog2.7.11.220.442
2c6o4SPCyclin-dependent kinase 22.7.11.220.442
2jkoBIJFocal adhesion kinase 12.7.10.20.442
2oo5TXDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
2r43G3GGag-Pol polyprotein3.4.23.160.442
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.442
2xp2VGHALK tyrosine kinase receptor2.7.10.10.442
2xvdAS6Ephrin type-B receptor 42.7.10.10.442
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.442
3u4uLNHCasein kinase II subunit alpha2.7.11.10.442
3w2sW2REpidermal growth factor receptor2.7.10.10.442
3w5tLHPVitamin D3 receptor/0.442
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4iaq2GM5-hydroxytryptamine receptor 1B/0.442
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.442
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.442
4yryFADGlutamate synthase, beta subunit/0.442
1ftlDNQGlutamate receptor 2/0.441
1hiiC20Gag-Pol polyprotein/0.441
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.441
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2j0m4STFocal adhesion kinase 12.7.10.20.441
2qd7065Gag-Pol polyprotein3.4.23.160.441
2uzbC75Cyclin-dependent kinase 22.7.11.220.441
2vtqLZACyclin-dependent kinase 22.7.11.220.441
2x1nX1NCyclin-dependent kinase 22.7.11.220.441
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.441
2xikJ60Serine/threonine-protein kinase 252.7.11.10.441
3r73X87Cyclin-dependent kinase 22.7.11.220.441
3vs3VSETyrosine-protein kinase HCK2.7.10.20.441
3wowANPCasein kinase II subunit alpha2.7.11.10.441
4a6cQG9Gag-Pol polyprotein3.4.23.160.441
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.441
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.441
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.441
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.441
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.441
4lv7ADPInositol-pentakisphosphate 2-kinase2.7.1.1580.441
4xiwAZMCarbonic anhydrase, alpha type/0.441
5auxKMPDeath-associated protein kinase 12.7.11.10.441
5dr6SKEAurora kinase A2.7.11.10.441
5iu86DZAdenosine receptor A2a/0.441
1hvlA76Gag-Pol polyprotein/0.440
1kl2FONSerine hydroxymethyltransferase/0.440
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.440
3d84NDPDihydrofolate reductase1.5.1.30.440
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.440
3lixE17Protease/0.440
3nwq2NCGag-Pol polyprotein3.4.23.160.440
3r7yZ04Cyclin-dependent kinase 22.7.11.220.440
3tm5SFGUncharacterized protein/0.440
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.440
4b7sQLECytochrome P450 monooxygenase PikC/0.440
4cd0AWJALK tyrosine kinase receptor2.7.10.10.440
4f650S9Fibroblast growth factor receptor 1/0.440
4i02CMPcAMP-activated global transcriptional regulator CRP/0.440
4pkhADPActin, alpha skeletal muscle/0.440
4ysjADPCalmodulin-like domain protein kinase/0.440