sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ust | FAD | AcMNPV orf92 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ust | FAD | AcMNPV orf92 | / | 1.000 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.568 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.513 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.512 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.499 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.499 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.497 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.494 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.491 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.491 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.488 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.488 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.486 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.482 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.482 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.482 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.481 | |
| 3nfr | EWQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.481 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.480 | |
| 1lke | DOG | Bilin-binding protein | / | 0.479 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.479 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.479 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2z4z | SC0 | Geranylgeranyl pyrophosphate synthase | / | 0.473 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.473 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.472 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.472 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.472 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.471 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.471 | |
| 1jr8 | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.470 | |
| 3cem | AVD | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.470 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.470 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.470 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.469 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.469 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.468 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.468 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3e6e | DCS | Alanine racemase | / | 0.467 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.467 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.467 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.467 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.467 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.466 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.466 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.466 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.466 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.466 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.465 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.465 | |
| 2vyx | FMN | Dodecin | / | 0.464 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3mbg | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.464 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.464 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.463 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.463 | |
| 3tk0 | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.463 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.462 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.462 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.462 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.462 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.462 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.461 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.461 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.461 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.461 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.461 | |
| 1jf0 | CZH | Obelin | / | 0.460 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.460 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.460 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.460 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.460 | |
| 1c7o | PPG | Hemolysin | / | 0.459 | |
| 1g7v | PAI | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.459 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.459 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.459 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.459 | |
| 3u2l | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.459 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.459 | |
| 1kqf | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.458 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.458 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.458 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.458 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.458 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.458 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.458 | |
| 4e0h | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.458 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.458 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.457 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.457 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.457 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.457 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.457 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.457 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.457 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.457 | |
| 4a6d | SAM | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.457 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 1el4 | CTZ | Obelin | / | 0.456 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.456 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.456 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.456 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.456 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 3u5s | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.456 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4kq2 | U5P | Glycogen [starch] synthase isoform 2 | 2.4.1.11 | 0.456 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.456 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.455 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.455 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.455 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2qbs | 024 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.455 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.455 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.455 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.454 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.453 | |
| 1qv1 | CZH | Obelin | / | 0.453 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.453 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.453 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.453 | |
| 2y02 | WHJ | Beta-1 adrenergic receptor | / | 0.453 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase | / | 0.453 | |
| 4hs4 | FMN | Chromate reductase | / | 0.453 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.453 | |
| 4nqg | CZH | Mitrocomin | / | 0.453 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.452 | |
| 1xp8 | AGS | Protein RecA | / | 0.452 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.452 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.452 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.452 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.452 | |
| 4gd9 | BTN | Streptavidin | / | 0.452 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.452 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.451 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.451 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 2wpw | ACO | Orf14 | / | 0.451 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.451 | |
| 2y01 | Y00 | Beta-1 adrenergic receptor | / | 0.451 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 4jdc | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.451 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.451 | |
| 5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.451 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 20gs | CBD | Glutathione S-transferase P | 2.5.1.18 | 0.450 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3c1o | NAP | Eugenol synthase | / | 0.450 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.450 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.450 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.450 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.450 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.449 | |
| 1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.449 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 2v19 | FMN | Dodecin | / | 0.449 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.449 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.449 | |
| 1eio | GCH | Gastrotropin | / | 0.448 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.448 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2bxq | IMN | Serum albumin | / | 0.448 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.448 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.448 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.448 | |
| 4h6p | FMN | Chromate reductase | / | 0.448 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4ami | G90 | Beta-1 adrenergic receptor | / | 0.448 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.447 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.447 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2tsr | UMP | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.447 | |
| 3dgq | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.447 | |
| 3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.447 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.447 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4eyb | 0WO | Metallo-beta-lactamase type 2 | / | 0.447 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.447 | |
| 4iwn | GEK | Carboxy-S-adenosyl-L-methionine synthase | / | 0.447 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 5efw | FMN | NPH1-1 | / | 0.447 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.446 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.446 | |
| 3nhu | M42 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.446 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.446 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.446 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4y9x | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.446 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1gti | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.445 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.445 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.445 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.445 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2amv | BIN | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.445 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.445 | |
| 3t58 | FAD | Sulfhydryl oxidase 1 | 1.8.3.2 | 0.445 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.445 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.445 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.445 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1oqc | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.444 | |
| 1pgt | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
| 1pua | COA | HAT A1 | / | 0.444 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.444 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3fe1 | ADP | Heat shock 70 kDa protein 6 | / | 0.444 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.444 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.444 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.444 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.444 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.444 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.444 | |
| 5e9e | ANP | Myosin heavy chain kinase A | 2.7.11.7 | 0.444 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.443 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.443 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.443 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4lb2 | DM5 | Serum albumin | / | 0.443 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.443 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.443 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.442 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.442 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.442 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.442 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.442 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1uhh | CZP | Aequorin-2 | / | 0.442 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.442 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.442 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.442 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.442 | |
| 2glr | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.442 | |
| 2oad | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.442 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.442 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.442 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.442 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3gwl | FAD | FAD-linked sulfhydryl oxidase | 1.8.3.2 | 0.442 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.442 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.442 | |
| 3pgt | GBX | Glutathione S-transferase P | 2.5.1.18 | 0.442 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.442 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.442 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 5fmm | MGT | Polymerase basic protein 2 | / | 0.442 | |
| 1e6v | COM | Methyl-coenzyme M reductase I subunit alpha | / | 0.441 | |
| 1e6v | COM | Methyl coenzyme M reductase, beta subunit | / | 0.441 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.441 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1s36 | CEI | Obelin | / | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.441 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.441 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.441 | |
| 2j9h | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.441 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3nhr | RZW | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.441 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.441 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.441 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.440 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.440 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.440 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3h0w | N8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.440 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.440 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3lpf | Z77 | Beta-glucuronidase | 3.2.1.31 | 0.440 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.440 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.440 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.440 | |
| 3zk6 | H1I | Bcl-2-like protein 1 | / | 0.440 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4o6f | SAH | N-lysine methyltransferase SMYD2 | / | 0.440 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.440 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.440 |