Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3oq6PFBAlcohol dehydrogenase E chain1.1.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3oq6PFBAlcohol dehydrogenase E chain1.1.1.11.000
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.813
4dwvPFBAlcohol dehydrogenase E chain1.1.1.10.743
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.677
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.670
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.670
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.662
5kj6PFBAlcohol dehydrogenase E chain1.1.1.10.661
5cdsPFBAlcohol dehydrogenase E chain1.1.1.10.653
4ng5PFBAlcohol dehydrogenase E chain1.1.1.10.651
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.648
5kcpPFBAlcohol dehydrogenase E chain1.1.1.10.640
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.516
1txiTX5Vitamin D3 receptor/0.511
3a783EVVitamin D3 receptor/0.504
2harOCCVitamin D3 receptor/0.499
2hasC3OVitamin D3 receptor/0.499
3w5p4OAVitamin D3 receptor/0.499
1y0s331Peroxisome proliferator-activated receptor delta/0.498
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.498
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.496
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.495
4ia3BIVVitamin D3 receptor A/0.495
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.494
3vt5YI2Vitamin D3 receptor/0.493
4nh82LCHeat shock protein HSP 90-alpha/0.492
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.491
3w0aDS5Vitamin D3 receptor/0.491
4uyf73BBromodomain-containing protein 2/0.491
1s0zEB1Vitamin D3 receptor/0.489
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.489
3vt3VDXVitamin D3 receptor/0.489
4hxyNDPPlm1/0.489
1db1VDXVitamin D3 receptor/0.487
1ie9VDXVitamin D3 receptor/0.487
2hb8MVDVitamin D3 receptor/0.487
2vbdV10Isopenicillin N synthase1.21.3.10.486
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.486
3gqvNAPEnoyl reductase LovC10.485
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.485
4jlj1NMDeoxycytidine kinase2.7.1.740.485
1zeoC01Peroxisome proliferator-activated receptor gamma/0.484
4oztP1AEcdysone receptor, putative/0.484
2hamC33Vitamin D3 receptor/0.483
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.483
1rkgVD1Vitamin D3 receptor/0.481
2bu9HFVIsopenicillin N synthase1.21.3.10.481
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.481
2po7CHDFerrochelatase, mitochondrial4.99.1.10.481
4fhh0U3Vitamin D3 receptor A/0.481
4awq592Heat shock protein HSP 90-alpha/0.480
4o71CPBBromodomain-containing protein 4/0.480
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
3vt7VDXVitamin D3 receptor/0.479
3w0yDS4Vitamin D3 receptor/0.479
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.479
2hb7O1CVitamin D3 receptor/0.478
3to6LYS_CMCHistone acetyltransferase ESA1/0.478
2c27ACOMycothiol acetyltransferase2.3.1.1890.477
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.477
4jufTPPBenzoylformate decarboxylase4.1.1.70.477
3rr3FLRProstaglandin G/H synthase 21.14.99.10.476
1nytNAPShikimate dehydrogenase (NADP(+))/0.475
2hcdBIVVitamin D3 receptor A/0.475
2pmdGNPTranslation initiation factor 2 subunit gamma/0.475
3begANPSRSF protein kinase 12.7.11.10.475
3vrwYS5Vitamin D3 receptor/0.475
3vt65YIVitamin D3 receptor/0.475
3vt9YI4Vitamin D3 receptor/0.475
3w0jT08Vitamin D3 receptor/0.475
5jlaNADPutative short-chain dehydrogenase/reductase/0.475
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.474
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
3dr1C5DVitamin D3 receptor A/0.474
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.474
3l6jZ90Alr2278 protein/0.474
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.474
5kgpACOPredicted acetyltransferase/0.474
1s19MC9Vitamin D3 receptor/0.473
2hbhXE4Vitamin D3 receptor A/0.473
3b70NAPEnoyl reductase LovC10.473
4iteTEYVitamin D3 receptor/0.473
4xldBRLPeroxisome proliferator-activated receptor gamma/0.473
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.472
2jb4A14Isopenicillin N synthase1.21.3.10.472
3qm4PN0Cytochrome P450 2D6/0.472
3w32W32Epidermal growth factor receptor2.7.10.10.472
4g2h0VQVitamin D3 receptor A/0.472
2q59240Peroxisome proliferator-activated receptor gamma/0.471
3bbrBHYGlutamate receptor 2/0.471
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.471
3gw9VNILanosterol 14-alpha-demethylase/0.471
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.471
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.471
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.470
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.470
3vtbTKAVitamin D3 receptor/0.470
3w0hW12Vitamin D3 receptor/0.470
1blzACVIsopenicillin N synthase1.21.3.10.469
1kkq471Peroxisome proliferator-activated receptor alpha/0.469
1mueCDDProthrombin3.4.21.50.469
1powFADPyruvate oxidase1.2.3.30.469
2znq401Peroxisome proliferator-activated receptor delta/0.469
3inxJZCHeat shock protein HSP 90-alpha/0.469
3w0gW07Vitamin D3 receptor/0.469
3zoiM2WIsopenicillin N synthase1.21.3.10.469
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.469
4ia7BIVVitamin D3 receptor A/0.469
4n9iPCGCatabolite expression activator/0.469
1rdt570Peroxisome proliferator-activated receptor gamma/0.468
3tk3CPZCytochrome P450 2B41.14.14.10.468
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.467
1rk3VDXVitamin D3 receptor/0.467
1zdwFLVPrenyltransferase/0.467
2z3uCRRCytochrome P450/0.467
3vrvYSDVitamin D3 receptor/0.467
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4h2nFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.467
4q0a4OAVitamin D3 receptor A/0.467
4rupH97Vitamin D3 receptor A/0.467
1nm6L86Prothrombin3.4.21.50.466
1s1vTNKGag-Pol polyprotein2.7.7.490.466
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.466
3vrtYS2Vitamin D3 receptor/0.466
4awo99BHeat shock protein HSP 90-alpha/0.466
4awp99AHeat shock protein HSP 90-alpha/0.466
4iah1DXAlr2278 protein/0.466
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.465
1hb3SCVIsopenicillin N synthase1.21.3.10.465
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.465
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.465
1zrzBI1Protein kinase C iota type2.7.11.130.465
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
2pobGW4Peroxisome proliferator-activated receptor gamma/0.465
2zlcVDXVitamin D3 receptor/0.465
3tdaPN0Cytochrome P450 2D6/0.465
3u4cNDPNADPH-dependent reductase BacG/0.465
4bb3KKAIsopenicillin N synthase1.21.3.10.465
4ejmNAPPutative zinc-binding dehydrogenase/0.465
4ia1BIVVitamin D3 receptor A/0.465
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.464
1hvyD16Thymidylate synthase2.1.1.450.464
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.464
2zb3NDPProstaglandin reductase 21.3.1.480.464
3inwJZBHeat shock protein HSP 90-alpha/0.464
3lsiFADPyranose 2-oxidase/0.464
3mjeNDPAmphB/0.464
4k9nTZDBenzoylformate decarboxylase4.1.1.70.464
1rkhVD2Vitamin D3 receptor/0.463
2pg0FADAcyl-CoA dehydrogenase/0.463
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.463
4k9oTPPBenzoylformate decarboxylase4.1.1.70.463
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.462
1ie8KH1Vitamin D3 receptor/0.462
1ppjANYCytochrome b/0.462
2a94AP0L-lactate dehydrogenase1.1.1.270.462
2uuj896Prothrombin3.4.21.50.462
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.462
3sf6FDAGlutaryl-CoA dehydrogenase/0.462
3vtdTKDVitamin D3 receptor/0.462
4g1z0VPVitamin D3 receptor A/0.462
4g210VPVitamin D3 receptor A/0.462
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.461
2q8sL92Peroxisome proliferator-activated receptor gamma/0.461
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.461
3cukFADD-amino-acid oxidase1.4.3.30.461
3kpzZNEVitamin D3 receptor/0.461
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.461
3oqfS51Renin3.4.23.150.461
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.461
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.461
4cfaWOPIntegrase/0.461
1bk0ACVIsopenicillin N synthase1.21.3.10.460
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.460
1rjkVDZVitamin D3 receptor/0.460
1z1fSTLResveratrol synthase/0.460
2iviACWIsopenicillin N synthase1.21.3.10.460
2xx91NFGlutamate receptor 2/0.460
3a1l2CCCytochrome P450/0.460
3gkjHC3Niemann-Pick C1 protein/0.460
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.460
4iae1DXAlr2278 protein/0.460
4l8u9AZSerum albumin/0.460
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.459
1k7l544Peroxisome proliferator-activated receptor alpha/0.459
1rt2TNKGag-Pol polyprotein2.7.7.490.459
1uzwCDHIsopenicillin N synthase1.21.3.10.459
2bjhFERFeruloyl esterase A3.1.1.730.459
2r2mI50Prothrombin3.4.21.50.459
2xgs44PUncharacterized protein/0.459
2xviFADPutative flavin-containing monooxygenase/0.459
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3hz5Z64Heat shock protein HSP 90-alpha/0.459
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.459
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.459
3vruYS3Vitamin D3 receptor/0.459
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.459
4fqsLYAThymidylate synthase ThyA/0.459
4i02CMPcAMP-activated global transcriptional regulator CRP/0.459
4l4xNDPAmphI/0.459
4l9q9TPSerum albumin/0.459
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.459
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.459
1c4yIH3Prothrombin3.4.21.50.458
1hnjMLC3-oxoacyl-[acyl-carrier-protein] synthase 3/0.458
2hk9NAPShikimate dehydrogenase (NADP(+))/0.458
2i0aMUIProtease/0.458
3d0bSNXHeat shock protein HSP 90-alpha/0.458
3t2yFADSulfide-quinone reductase/0.458
3tz3B36Acetyl-CoA carboxylase/0.458
3vt45YIVitamin D3 receptor/0.458
4b7sQLECytochrome P450 monooxygenase PikC/0.458
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.458
4nb6444Nuclear receptor ROR-gamma/0.458
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
5jscFADPutative acyl-CoA dehydrogenase/0.458
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1xzqFONtRNA modification GTPase MnmE3.6.50.457
2ou2ACOHistone acetyltransferase KAT5/0.457
2q4bNAPUncharacterized protein At5g02240/0.457
2xlrNAPPutative flavin-containing monooxygenase/0.457
2yy7NADL-threonine dehydrogenase/0.457
3l0lHC3Nuclear receptor ROR-gamma/0.457
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.457
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.457
3w0c6DSVitamin D3 receptor/0.457
4a83DXCMajor pollen allergen Bet v 1-A/0.457
4b4vL34Bifunctional protein FolD/0.457
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.457
1k74544Peroxisome proliferator-activated receptor gamma/0.456
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.456
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.456
2o4rVD5Vitamin D3 receptor/0.456
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.456
3nx4NAPPutative oxidoreductase/0.456
3w0iO11Vitamin D3 receptor/0.456
4aguD15Cyclin-dependent kinase-like 1/0.456
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.456
4gg1TZDBenzoylformate decarboxylase4.1.1.70.456
4jubTPPBenzoylformate decarboxylase4.1.1.70.456
4l9kEHFSerum albumin/0.456
4rujVDXVitamin D3 receptor A/0.456
1eioGCHGastrotropin/0.455
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.455
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.455
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.455
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.455
2zlaVDBVitamin D3 receptor/0.455
3ghwGHWDihydrofolate reductase1.5.1.30.455
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.455
3slkNDPPolyketide synthase extender module 2/0.455
4bqg50QHeat shock protein HSP 90-alpha/0.455
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
4ej0NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.455
4g1y0VOVitamin D3 receptor A/0.455
4hjoAQ4Epidermal growth factor receptor2.7.10.10.455
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.455
4k9pTPPBenzoylformate decarboxylase4.1.1.70.455
4qi4FADCellobiose dehydrogenase/0.455
4r21STRCytochrome P450 family 17 polypeptide 2/0.455
5cb5APRO-acetyl-ADP-ribose deacetylase/0.455
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1nzdUPGDNA beta-glucosyltransferase/0.454
1pr9NAPL-xylulose reductase1.1.1.100.454
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.454
1qiqACCIsopenicillin N synthase1.21.3.10.454
2gv8NDPThiol-specific monooxygenase1.14.130.454
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.454
2vn0TDZCytochrome P450 2C8/0.454
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.454
4g3jVNTLanosterol 14-alpha-demethylase/0.454
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.454
1h2bNAJNAD-dependent alcohol dehydrogenase/0.453
1ipeNDPTropinone reductase 21.1.1.2360.453
1u3dFADCryptochrome-1/0.453
1unlRRCCyclin-dependent-like kinase 52.7.11.10.453
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.453
3dejRXCCaspase-33.4.22.560.453
3h18PMSEsterase/lipase/0.453
3lqfNADGalactitol dehydrogenase/0.453
3p99LNPLanosterol 14-alpha-demethylase/0.453
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
4itfTFYVitamin D3 receptor/0.453
5kl9COAAcyl-CoA thioester hydrolase YbgC3.1.20.453
1g6oADPCag alpha/0.452
1hncGDNGlutathione S-transferase Mu 22.5.1.180.452
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.452
2znpK55Peroxisome proliferator-activated receptor delta/0.452
3ajrNADNDP-sugar epimerase/0.452
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.452
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.452
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.452
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.452
3uylTYDProbable NDP-rhamnosyltransferase/0.452
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4jk4DIUSerum albumin/0.452
4q71FADBifunctional protein PutA/0.452
4wloNAIMalate dehydrogenase, mitochondrial1.1.1.370.452
5br7FADUDP-galactopyranose mutase/0.452
5c1mCLRMu-type opioid receptor/0.452
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.452
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.452
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.452
1jujLYAThymidylate synthase2.1.1.450.451
1phgMYTCamphor 5-monooxygenase1.14.15.10.451
1rj6AZMCarbonic anhydrase 144.2.1.10.451
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.451
1wn3HXCPhenylacetic acid degradation protein PaaI/0.451
1xddAAYIntegrin alpha-L/0.451
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.451
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.451
2rg5279Mitogen-activated protein kinase 14/0.451
2wsbNADGalactitol dehydrogenase/0.451
3lu8IQXSerum albumin/0.451
3pe2E1BCasein kinase II subunit alpha2.7.11.10.451
3t2zFADSulfide-quinone reductase/0.451
3tvuB37Acetyl-CoA carboxylase/0.451
3vt8YI3Vitamin D3 receptor/0.451
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4impNDPPolyketide synthase extender modules 3-4/0.451
4ku5DCC3-oxoacyl-[ACP] synthase III/0.451
5hs1VORLanosterol 14-alpha demethylase/0.451
1cbqRE9Cellular retinoic acid-binding protein 2/0.450
1hb1OCVIsopenicillin N synthase1.21.3.10.450
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.450
1oc1ASVIsopenicillin N synthase1.21.3.10.450
1qjfACSIsopenicillin N synthase1.21.3.10.450
1zioAP5Adenylate kinase/0.450
2hc4VDXVitamin D3 receptor A/0.450
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.450
2o4jVD4Vitamin D3 receptor/0.450
2uxoTACHTH-type transcriptional regulator TtgR/0.450
2zl9VDAVitamin D3 receptor/0.450
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3r5zF42Uncharacterized protein/0.450
3sz0FADSulfide-quinone reductase/0.450
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.450
4a84DXCMajor pollen allergen Bet v 1-A/0.450
4ez8DHFThymidylate synthase2.1.1.450.450
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.450
4fhi0S4Vitamin D3 receptor A/0.450
4irnFADAnaB/0.450
4ruoBIVVitamin D3 receptor A/0.450
4uyg73BBromodomain-containing protein 2/0.450
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.450
5k2aZMAAdenosine receptor A2a/0.450
1cqp803Integrin alpha-L/0.449
1mu6CDAProthrombin3.4.21.50.449
1snyNAPLD36273p/0.449
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.449
2o12FMNChorismate synthase/0.449
2ow9SP6Collagenase 33.4.240.449
2zfr46UProthrombin3.4.21.50.449
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.449
3d7zGK5Mitogen-activated protein kinase 14/0.449
3owaFADAcyl-CoA dehydrogenase/0.449
3stv3HOMethylketone synthase I/0.449
4b4w9L9Bifunctional protein FolD/0.449
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4gyiADPUncharacterized protein/0.449
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.449
5k2cZMAAdenosine receptor A2a/0.449
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1mrwK57Gag-Pol polyprotein3.4.23.160.448
1npvL27Gag-Pol polyprotein3.4.23.160.448
1wuuANPGalactokinase2.7.1.60.448
2ath3EAPeroxisome proliferator-activated receptor gamma/0.448
2fzwNADAlcohol dehydrogenase class-31.1.1.10.448
2omeNADC-terminal-binding protein 2/0.448
2p5uNADUDP-glucose 4-epimerase/0.448
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.448
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
4asf62UATP-dependent molecular chaperone HSP82/0.448
4i3wNADAldehyde dehydrogenase (NAD+)/0.448
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.448
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.448
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.448
4xyeNADFormate dehydrogenase/0.448
4yagNAIC alpha-dehydrogenase/0.448
1e3eNAIAlcohol dehydrogenase 41.1.1.10.447
1fmlRTLRetinol dehydratase/0.447
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.447
1mczTDPBenzoylformate decarboxylase4.1.1.70.447
1olmVTQSEC14-like protein 2/0.447
1p8dCO1Oxysterols receptor LXR-beta/0.447
1phhFADp-hydroxybenzoate hydroxylase/0.447
1ygjRMCPyridoxal kinase2.7.1.350.447
2dteNAIGlucose 1-dehydrogenase related protein/0.447
2e48FADD-amino-acid oxidase1.4.3.30.447
2pksG44Prothrombin3.4.21.50.447
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.447
2vbpVB1Isopenicillin N synthase1.21.3.10.447
2vcmM11Isopenicillin N synthase1.21.3.10.447
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.447
3h3sH15Collagen type IV alpha-3-binding protein/0.447
3jzdNADMaleylacetate reductase/0.447
3te4ACODopamine N-acetyltransferase/0.447
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.447
3zuxTCHTransporter/0.447
4a802ANMajor pollen allergen Bet v 1-A/0.447
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.447
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.447
5h8tRTLRetinol-binding protein 1/0.447
1ci7CB3Thymidylate synthase2.1.1.450.446
1cs4GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.446
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.446
1pz1NAPGeneral stress protein 69/0.446
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.446
1upw444Oxysterols receptor LXR-beta/0.446
2bx8AZQSerum albumin/0.446
2fdpFRPBeta-secretase 13.4.23.460.446
2fr3REACellular retinoic acid-binding protein 2/0.446
2uxpCLMHTH-type transcriptional regulator TtgR/0.446
2vnaNAPProstaglandin reductase 21.3.1.480.446
3biu10UProthrombin3.4.21.50.446
3cgcCOACoenzyme A disulfide reductase/0.446
3dl0AP5Adenylate kinase/0.446
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3gwfFADCyclohexanone monooxygenase/0.446
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.446
3kpkFADSulfide-quinone reductase/0.446
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3v3m0ENReplicase polyprotein 1a3.4.19.120.446
3v9y24LPeroxisome proliferator-activated receptor gamma/0.446
3zkyWT4Isopenicillin N synthase1.21.3.10.446
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.446
4g7gVFVLanosterol 14-alpha-demethylase/0.446
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.446
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.446
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.446
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.446
1agwSU2Fibroblast growth factor receptor 1/0.445
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.445
1kt3RTLRetinol-binding protein 4/0.445
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1xe55FEPlasmepsin-23.4.23.390.445
1ygkRRCPyridoxal kinase2.7.1.350.445
2cig1DGDihydrofolate reductase1.5.1.30.445
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.445
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.445
2xw7NDPDihydrofolate reductase/0.445
3bheBZNGag-Pol polyprotein3.4.23.160.445
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.445
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3k9uACOSpermidine N(1)-acetyltransferase/0.445
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3oafOAGDihydrofolate reductase1.5.1.30.445
3opdHIEHeat shock protein 83/0.445
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.445
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.445
3w5tLHPVitamin D3 receptor/0.445
4a8v2ANMajor pollen allergen Bet v 1-J/0.445
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.445
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4gm4TZDBenzoylformate decarboxylase4.1.1.70.445
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.445
4jazSTLPeroxisome proliferator-activated receptor gamma/0.445
4jx1CAHCamphor 5-monooxygenase1.14.15.10.445
4lisNADUDP-glucose 4-epimerase (Eurofung)/0.445
4xiwAZMCarbonic anhydrase, alpha type/0.445
5ifyTRHGlucose-1-phosphate thymidylyltransferase/0.445
5stdUNNScytalone dehydratase4.2.1.940.445
1iy8NADLevodione reductase/0.444
1jioDEB6-deoxyerythronolide B hydroxylase/0.444
1k6tXN1Gag-Pol polyprotein3.4.23.160.444
1me6IVSPlasmepsin-23.4.23.390.444
1ndzFR5Adenosine deaminase3.5.4.40.444
1p0hACOMycothiol acetyltransferase2.3.1.1890.444
1poxFADPyruvate oxidase1.2.3.30.444
1qvnFRIInterleukin-2/0.444
1r2jFADFkbI/0.444
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.444
1yszNECEndoplasmin/0.444
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.444
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.444
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.444
2cbrA80Cellular retinoic acid-binding protein 1/0.444
2hejNDPAldo-keto reductase family 1 member C211.1.10.444
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.444
2zfnACOHistone acetyltransferase RTT1092.3.1.480.444
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.444
3kduNKSPeroxisome proliferator-activated receptor alpha/0.444
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.444
3t14FADSulfide-quinone reductase/0.444
3ukuC69Actin-related protein 3/0.444
4ax9N5NProthrombin3.4.21.50.444
4bj9UHBTankyrase-22.4.2.300.444
4dh60KNBeta-secretase 13.4.23.460.444
4ly91YYGlucokinase regulatory protein/0.444
4qi5FADCellobiose dehydrogenase/0.444
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.444
4uymVOR14-alpha sterol demethylase Cyp51B/0.444
5kghACOPredicted acetyltransferase/0.444
1fm9570Peroxisome proliferator-activated receptor gamma/0.443
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.443
1j49NADD-lactate dehydrogenase1.1.1.280.443
1jwtBLIProthrombin3.4.21.50.443
1pqc444Oxysterols receptor LXR-beta/0.443
1qrpHH0Pepsin A-43.4.23.10.443
1uy8PU5Heat shock protein HSP 90-alpha/0.443
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.443
2iyaZIOOleandomycin glycosyltransferase/0.443
2jh0701Prothrombin3.4.21.50.443
2pauD5M5'-deoxynucleotidase YfbR/0.443
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.443
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.443
2ykjYKJHeat shock protein HSP 90-alpha/0.443
2yutNAPPutative short-chain oxidoreductase/0.443
3bg7FADPyranose 2-oxidase/0.443
3cid318Beta-secretase 13.4.23.460.443
3d3wNAPL-xylulose reductase1.1.1.100.443
3gobHXXDdmC/0.443
3iaeD7KBenzaldehyde lyase/0.443
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.443
3oxv478Gag-Pol polyprotein3.4.23.160.443
3s55NADPutative short-chain dehydrogenase/reductase/0.443
3toxNAPPutative oxidoreductase/0.443
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.443
3w5rLOAVitamin D3 receptor/0.443
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.443
4n3l2FNProthrombin3.4.21.50.443
1bdmNAXMalate dehydrogenase/0.442
1c6yMK1Protease/0.442
1lf2R37Plasmepsin-23.4.23.390.442
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.442
1wntNAPL-xylulose reductase1.1.1.100.442
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.442
1yhjR6CPyridoxal kinase2.7.1.350.442
1ypeUIPProthrombin3.4.21.50.442
2bdyUNBProthrombin3.4.21.50.442
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.442
2fznFADBifunctional protein PutA1.5.5.20.442
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.442
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.442
2k5tCOAPanD regulatory factor/0.442
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2q5p241Peroxisome proliferator-activated receptor gamma/0.442
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.442
2y6fM9FIsopenicillin N synthase1.21.3.10.442
2zc922UProthrombin3.4.21.50.442
2zgx29UProthrombin3.4.21.50.442
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.442
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
3dleGFAGag-Pol polyprotein2.7.7.490.442
3dmjGWEPol protein/0.442
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.442
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
3m9vTYDFAD-dependent oxidoreductase/0.442
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
3nbvANPKetohexokinase/0.442
3rj9NADAlcohol dehydrogenase1.1.1.10.442
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.442
3zkuHCVIsopenicillin N synthase1.21.3.10.442
4a99FADTetX family tetracycline inactivation enzyme/0.442
4dfrMTXDihydrofolate reductase1.5.1.30.442
4ead0NPThymidine phosphorylase2.4.2.40.442
4emaBRLPeroxisome proliferator-activated receptor gamma/0.442
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.442
4gapNADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4gh5NADShort-chain dehydrogenase/reductase SDR/0.442
4tuvCPZCytochrome P450 1191.140.442
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.442
5byuCOAThioesterase/0.442
5k2bZMAAdenosine receptor A2a/0.442
1bygSTUTyrosine-protein kinase CSK/0.441
1dkfBMSRetinoic acid receptor alpha/0.441
1fxsNAPGDP-L-fucose synthase/0.441
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.441
1kzjCB3Thymidylate synthase/0.441
1ng3FADGlycine oxidase1.4.3.190.441
1ryiFADGlycine oxidase1.4.3.190.441
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.441
2c29NAPDihydroflavonol 4-reductase/0.441
2g37FADProline dehydrogenase/0.441
2iqgF2IBeta-secretase 13.4.23.460.441
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.441
2qimZEAClass 10 plant pathogenesis-related protein/0.441
2qo9ANPEphrin type-A receptor 32.7.10.10.441
2uxzHI1Gag-Pol polyprotein3.4.23.160.441
2w0dCGSMacrophage metalloelastase3.4.24.650.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2y3rTRKTamL/0.441
3bhrTHGThymidylate synthase/0.441
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.441
3imxB84Glucokinase2.7.1.20.441
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3jv7NADSecondary alcohol dehydrogenase/0.441
3melTPPThiamin pyrophosphokinase family protein/0.441
3mjhGTPRas-related protein Rab-5A/0.441
3nw3MU2Peptidoglycan recognition protein 1/0.441
3o6o94MHeat shock protein 83/0.441
3q33ACOHistone acetyltransferase RTT1092.3.1.480.441
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.441
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.441
3v49PK0Androgen receptor/0.441
4ambDUDPutative glycosyl transferase/0.441
4bhw01KHistone acetyltransferase p300/0.441
4c58824Cyclin-G-associated kinase2.7.11.10.441
4dl9NADS-(hydroxymethyl)glutathione dehydrogenase/0.441
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4j6cSTRCytochrome P450 monooxygenase/0.441
4jbqVX6Aurora kinase A2.7.11.10.441
4locBTNPyruvate carboxylase/0.441
4o2bLOCTubulin beta-2B chain/0.441
4phlPILPhosphodiesterase/0.441
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
1d6w00RProthrombin3.4.21.50.440
1fm4DXCMajor pollen allergen Bet v 1-L/0.440
1gj5130Prothrombin3.4.21.50.440
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1mjbACOHistone acetyltransferase ESA1/0.440
1msmJE2Gag-Pol polyprotein3.4.23.160.440
1mvtDTMDihydrofolate reductase1.5.1.30.440
1pkfEPDEpothilone C/D epoxidase1.140.440
1uycPU7Heat shock protein HSP 90-alpha/0.440
2rlcCHDCholoylglycine hydrolase3.5.1.240.440
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.440
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
3b1pNOSPfkB carbohydrate kinase family protein/0.440
3bc3OPTCathepsin L13.4.22.150.440
3mnrSD1Heat shock protein HSP 90-alpha/0.440
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.440
3phiNDPShikimate dehydrogenase (NADP(+))/0.440
3wleNAD(R)-specific carbonyl reductase/0.440
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.440
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.440
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.440
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4dbzNDPPutative ketoacyl reductase1.3.10.440
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.440
4j6dTESCytochrome P450 monooxygenase/0.440
4kcfAKMFAD-dependent oxidoreductase/0.440
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.440
4rvnCOAPhenylacetate-coenzyme A ligase/0.440
5f0a1FBcGMP-dependent protein kinase, putative/0.440
5idwNAPShort-chain dehydrogenase/reductase SDR/0.440