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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/1.000
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.652
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.590
1g6kNADGlucose 1-dehydrogenase1.1.1.470.585
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.575
4dc0NDPPutative ketoacyl reductase1.3.10.562
4k6fNAPPutative Acetoacetyl-CoA reductase/0.561
4wecNADShort chain dehydrogenase/0.558
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.558
4b79NADProbable short-chain dehydrogenase/0.543
4dbzNDPPutative ketoacyl reductase1.3.10.539
4esoNAPPutative oxidoreductase/0.539
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.536
4nbwNADShort-chain dehydrogenase/reductase SDR/0.531
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.526
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.523
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.523
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.521
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.520
1b2lNDCAlcohol dehydrogenase1.1.1.10.518
5jlaNADPutative short-chain dehydrogenase/reductase/0.518
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.513
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.513
1x7gNAPPutative ketoacyl reductase1.3.10.512
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.512
3toxNAPPutative oxidoreductase/0.511
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.509
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.508
3lqfNADGalactitol dehydrogenase/0.508
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.507
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.506
1x7hNDPPutative ketoacyl reductase1.3.10.506
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.505
4yagNAIC alpha-dehydrogenase/0.504
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.503
1e3wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.501
1rwbNADGlucose 1-dehydrogenase1.1.1.470.501
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.501
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.500
3autNAIGlucose 1-dehydrogenase 41.1.1.470.500
2c29NAPDihydroflavonol 4-reductase/0.499
1q6t600Tyrosine-protein phosphatase non-receptor type 13.1.3.480.498
2c12FADNitroalkane oxidase1.7.3.10.497
3junAKDPhenazine biosynthesis protein A/B/0.497
4u7wNDPMxaA/0.497
1w4zNAPPutative ketoacyl reductase1.3.10.496
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.492
3mjeNDPAmphB/0.492
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.491
4hwkNAPSepiapterin reductase1.1.1.1530.491
4lcjNADC-terminal-binding protein 2/0.491
2ejvNADL-threonine 3-dehydrogenase/0.490
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.490
4ure1PSCyclohexanol dehydrogenase/0.490
3ai2NDPNADPH-sorbose reductase/0.489
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.489
4yaiNAIC alpha-dehydrogenase/0.489
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.488
4hxyNDPPlm1/0.488
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.487
2wdzNADGalactitol dehydrogenase/0.487
3ai3NDPNADPH-sorbose reductase/0.487
3qt62P0Mevalonate diphosphate decarboxylase/0.487
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.486
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.485
4fdaNAP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.485
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.485
1w73NAP2,4-dienoyl-CoA reductase, mitochondrial1.3.1.340.483
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.483
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.482
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.482
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.482
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.481
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.481
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.481
4j7xNAPSepiapterin reductase1.1.1.1530.481
1hdrNADDihydropteridine reductase1.5.1.340.480
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
4blrUTPNTPase P4/0.480
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.479
4ambDUDPutative glycosyl transferase/0.479
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.479
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.479
1cdoNADAlcohol dehydrogenase 11.1.1.10.478
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.478
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.478
2iko7IGRenin3.4.23.150.477
1kp3ATPArgininosuccinate synthase6.3.4.50.476
2g1n1IGRenin3.4.23.150.476
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.476
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.475
2qrqS13Glycogen phosphorylase, muscle form2.4.1.10.474
1zemNADXylitol dehydrogenase/0.473
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.472
3h4vNAPPteridine reductase 11.5.1.330.472
4xguADPPutative pachytene checkpoint protein 2/0.472
5idwNAPShort-chain dehydrogenase/reductase SDR/0.472
1q84TZ4Acetylcholinesterase3.1.1.70.471
2g1y5IGRenin3.4.23.150.471
2zvbSAHPrecorrin-3 C17-methyltransferase/0.471
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.471
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.471
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.471
1culFOKAdenylate cyclase type 2/0.470
1culFOKAdenylate cyclase type 5/0.470
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.470
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.470
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.469
2b3dFADModulator of drug activity B/0.469
2ikuLIYRenin3.4.23.150.469
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.469
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.469
4qecNAPElxO/0.469
3d91REMRenin3.4.23.150.468
3iocA5DPantothenate synthetase6.3.2.10.468
3qe2FMNNADPH--cytochrome P450 reductase/0.468
2ckmAA7Acetylcholinesterase3.1.1.70.467
2g247IGRenin3.4.23.150.467
3qrwNDPPutative ketoacyl reductase1.3.10.467
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.467
4enhFVXCholesterol 24-hydroxylase/0.467
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.467
1f8fNADBenzyl alcohol dehydrogenase/0.466
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.466
3bk2U5PRibonuclease J/0.466
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.466
2b58COADiamine acetyltransferase 1/0.465
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.465
3b9lAZZSerum albumin/0.465
4fxy0W2Neurolysin, mitochondrial3.4.24.160.465
4tm1FDAKtzI/0.465
1hkuNADC-terminal-binding protein 11.1.10.464
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.464
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.464
4tyqAP5Adenylate kinase/0.464
1n5dNDPCarbonyl reductase [NADPH] 1/0.463
1udaUFGUDP-glucose 4-epimerase5.1.3.20.463
2bd0NAPSepiapterin reductase/0.463
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.463
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.463
2qbuSAHPrecorrin-2 methyltransferase/0.463
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.463
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.463
3f1kNAPUncharacterized oxidoreductase YciK10.463
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.463
4tlxFDAKtzI/0.463
1gcoNADGlucose 1-dehydrogenase1.1.1.470.462
1h51FMNPentaerythritol tetranitrate reductase/0.462
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.462
3phiNDPShikimate dehydrogenase (NADP(+))/0.462
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1yqzCOACoenzyme A disulfide reductase/0.461
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.461
4bftZVTPantothenate kinase2.7.1.330.461
4g7gVFVLanosterol 14-alpha-demethylase/0.461
4i1iNADMalate dehydrogenase/0.461
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.461
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.461
1h50FMNPentaerythritol tetranitrate reductase/0.460
1x1aSAMC-20 methyltransferase/0.460
2r8oT5XTransketolase 1/0.460
3cosNADAlcohol dehydrogenase 41.1.1.10.460
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.460
4b68FADL-ornithine N(5)-monooxygenase/0.460
4g3jVNTLanosterol 14-alpha-demethylase/0.460
4oqyNDP(S)-imine reductase/0.460
1guyNADMalate dehydrogenase/0.459
1hetNADAlcohol dehydrogenase E chain1.1.1.10.459
2ok7FADFerredoxin--NADP reductase, apicoplast/0.459
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.459
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.459
3imgBZ2Pantothenate synthetase6.3.2.10.459
1bsvNDPGDP-L-fucose synthase/0.458
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.458
1xddAAYIntegrin alpha-L/0.458
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.458
3af1GDPPantothenate kinase2.7.1.330.458
3ik6HCZGlutamate receptor 2/0.458
3nsh957Beta-secretase 13.4.23.460.458
4i0i957Beta-secretase 13.4.23.460.458
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.458
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.458
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.457
2ydxNAPMethionine adenosyltransferase 2 subunit beta/0.457
3coy53HPantothenate synthetase6.3.2.10.457
3e8xNAPBH1520 protein/0.457
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.457
3u8l09QAcetylcholine-binding protein/0.457
3uylTYDProbable NDP-rhamnosyltransferase/0.457
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.457
4psbGA3Cytokinin-specific binding protein/0.457
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.456
1gv0NADMalate dehydrogenase/0.456
1odcA8BAcetylcholinesterase3.1.1.70.456
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.456
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.456
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.456
3ohh3HHBeta-secretase 13.4.23.460.456
3p62FMNPentaerythritol tetranitrate reductase/0.456
4du82P0Mevalonate diphosphate decarboxylase/0.456
4mkhAP5Adenylate kinase/0.456
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.456
1dgmADNAdenosine kinase2.7.1.200.455
1fxsNAPGDP-L-fucose synthase/0.455
1pqc444Oxysterols receptor LXR-beta/0.455
2g1o2IGRenin3.4.23.150.455
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.455
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.455
2x97RX4Angiotensin-converting enzyme3.4.15.10.455
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.455
3dt2GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.455
4dc1NDPPutative ketoacyl reductase1.3.10.455
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.455
4r81FMNPredicted NADH dehydrogenase/0.455
1ek5NADUDP-glucose 4-epimerase/0.454
1fk8NAD3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase1.1.1.500.454
1gegNADDiacetyl reductase [(S)-acetoin forming]1.1.1.3040.454
1q23FUAChloramphenicol acetyltransferase2.3.1.280.454
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.454
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.454
2iyfERYOleandomycin glycosyltransferase2.4.10.454
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.454
2xukTZ5Acetylcholinesterase3.1.1.70.454
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.454
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.454
3rpeFADPutative modulator of drug activity/0.454
3s55NADPutative short-chain dehydrogenase/reductase/0.454
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.454
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.454
4kwhNAPReductase homolog/0.454
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.454
4opiFDAConserved Archaeal protein/0.454
5f8fSFGPossible transcriptional regulatory protein/0.454
1mj9COAHistone acetyltransferase ESA1/0.453
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.453
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.453
3gfbNADL-threonine 3-dehydrogenase/0.453
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
5d3qGDPDynamin-13.6.5.50.453
1eioGCHGastrotropin/0.452
1esmCOAPantothenate kinase2.7.1.330.452
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.452
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1pr9NAPL-xylulose reductase1.1.1.100.452
1tehNADAlcohol dehydrogenase class-31.1.1.10.452
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.452
2oapANPType II secretion system protein (GspE-2)/0.452
3oetNADErythronate-4-phosphate dehydrogenase/0.452
4a862ANMajor pollen allergen Bet v 1-A/0.452
4q0kGA3Phytohormone-binding protein/0.452
4r21STRCytochrome P450 family 17 polypeptide 2/0.452
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.452
1cjtFOKAdenylate cyclase type 2/0.451
1cjtFOKAdenylate cyclase type 5/0.451
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.451
1p0pBCHCholinesterase3.1.1.80.451
1rp0AHZThiamine thiazole synthase, chloroplastic/0.451
1txtCAAHMG-CoA synthase/0.451
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.451
2zvcSAHPrecorrin-3 C17-methyltransferase/0.451
4gl4NAIAlcohol dehydrogenase class-3/0.451
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.451
1fy7COAHistone acetyltransferase ESA1/0.450
3bj7COADiamine acetyltransferase 1/0.450
3h3qH13Collagen type IV alpha-3-binding protein/0.450
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.450
3hekBD0Heat shock protein HSP 90-alpha/0.450
3juqAJDPhenazine biosynthesis protein A/B/0.450
3sx2NADUncharacterized protein/0.450
4hnhNAPNAD-dependent epimerase/dehydratase/0.450
4djhJDCKappa-type opioid receptor/0.450
1gj4132Prothrombin3.4.21.50.449
1gssLEEGlutathione S-transferase P2.5.1.180.449
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.449
1tqf32PBeta-secretase 13.4.23.460.449
1ur5NADMalate dehydrogenase/0.449
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.449
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.449
2c20NADUDP-glucose 4-epimerase/0.449
2fxfACODiamine acetyltransferase 1/0.449
2g226IGRenin3.4.23.150.449
2is0I03Beta-secretase 13.4.23.460.449
2p5uNADUDP-glucose 4-epimerase/0.449
2vkeTACTetracycline repressor protein class D/0.449
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3qizQI2Botulinum neurotoxin type A3.4.24.690.449
4dptAGSMevalonate diphosphate decarboxylase/0.449
4egbNADdTDP-glucose 4,6-dehydratase/0.449
1drhNAPDihydrofolate reductase1.5.1.30.448
2ge3ACOProbable acetyltransferase/0.448
2gvdFKPAdenylate cyclase type 2/0.448
2gvdFKPAdenylate cyclase type 5/0.448
2q9fC3SCholesterol 24-hydroxylase/0.448
2vetUMPThymidylate synthase/0.448
3af3GCPPantothenate kinase2.7.1.330.448
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3pkbY16Methionine aminopeptidase 2/0.448
4a83DXCMajor pollen allergen Bet v 1-A/0.448
4b65FADL-ornithine N(5)-monooxygenase/0.448
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.448
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.448
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.448
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.448
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.448
5jy1NADPutative short-chain dehydrogenase/reductase/0.448
1h63FMNPentaerythritol tetranitrate reductase/0.447
1vf3GDNGlutathione S-transferase 32.5.1.180.447
2il2LIXRenin3.4.23.150.447
3ak4NADNADH-dependent quinuclidinone reductase/0.447
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3gegNADShort-chain dehydrogenase/reductase SDR/0.447
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.447
3sjuNDPKeto reductase/0.447
3wdsNADNADH-dependent quinuclidinone reductase/0.447
4an4DUDPutative glycosyl transferase/0.447
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.447
4j0v1H7Beta-secretase 13.4.23.460.447
1h74ADPHomoserine kinase2.7.1.390.446
1ja1FMNNADPH--cytochrome P450 reductase/0.446
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.446
1owe675Urokinase-type plasminogen activator3.4.21.730.446
1u1f183Uridine phosphorylase2.4.2.30.446
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.446
2gv8NDPThiol-specific monooxygenase1.14.130.446
3fktSIIBeta-secretase 13.4.23.460.446
3h3t16HCollagen type IV alpha-3-binding protein/0.446
3qiyQI1Botulinum neurotoxin type A3.4.24.690.446
3sxjSAMPutative methyltransferase/0.446
4dieC5PCytidylate kinase/0.446
4tlzNAPKtzI/0.446
4yaoFMNNADPH--cytochrome P450 reductase/0.446
5kwvANPPantothenate synthetase/0.446
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.445
1eveE20Acetylcholinesterase3.1.1.70.445
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.445
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
2pncCLUPrimary amine oxidase, liver isozyme/0.445
2vwqNAPGlucose 1-dehydrogenase/0.445
2xuqTZ4Acetylcholinesterase3.1.1.70.445
3a3gDLZLumazine protein/0.445
3apwDP0Alpha-1-acid glycoprotein 2/0.445
3f63GTXGlutathione transferase GST1-4/0.445
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.445
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.445
4zolGTPTubulin alpha-1B chain/0.445
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.445
5kcpNAJAlcohol dehydrogenase E chain1.1.1.10.445
1w6hTITPlasmepsin-23.4.23.390.444
2cjfRP43-dehydroquinate dehydratase4.2.1.100.444
2dvlFADAcyl-CoA dehydrogenase/0.444
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.444
2ixaNADAlpha-N-acetylgalactosaminidase3.2.1.490.444
2vwhNAPGlucose 1-dehydrogenase/0.444
2xhd7T9Glutamate receptor 2/0.444
2xvv9DNSerum albumin/0.444
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.444
3c3xNAPEugenol synthase 11.1.1.3180.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3q9bB3NAcetylpolyamine amidohydrolase/0.444
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.444
4b63NAPL-ornithine N(5)-monooxygenase/0.444
4fm80UQBeta-secretase 13.4.23.460.444
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1h62ANBPentaerythritol tetranitrate reductase/0.443
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.443
1obnASVIsopenicillin N synthase1.21.3.10.443
2gywOBIAcetylcholinesterase3.1.1.70.443
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.443
2r8pT6FTransketolase 1/0.443
2v16C47Renin3.4.23.150.443
3ggoNAIPrephenate dehydrogenase/0.443
3ihgVAKAklavinone 12-hydroxylase RdmE/0.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.443
4eb7PLPCysteine desulfurase IscS 2/0.443
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.443
4rquNADAlcohol dehydrogenase class-P/0.443
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.443
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.442
1cs4FOKAdenylate cyclase type 2/0.442
1cs4FOKAdenylate cyclase type 5/0.442
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.442
1h60STRPentaerythritol tetranitrate reductase/0.442
1jmhUMPThymidylate synthase/0.442
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.442
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1t2cNAIL-lactate dehydrogenase1.1.1.270.442
1xe55FEPlasmepsin-23.4.23.390.442
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.442
2bjfDXCCholoylglycine hydrolase3.5.1.240.442
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.442
3orfNADDihydropteridine reductase1.5.1.340.442
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
3wagTYDGlycosyltransferase/0.442
4c49HCYCorticosteroid-binding globulin/0.442
4frkDWDBeta-secretase 13.4.23.460.442
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.442
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.442
1cscCMCCitrate synthase, mitochondrial2.3.3.10.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.441
1mjaCOAHistone acetyltransferase ESA1/0.441
2g1r3IGRenin3.4.23.150.441
2q3eNAIUDP-glucose 6-dehydrogenase1.1.1.220.441
2xugTZ4Acetylcholinesterase3.1.1.70.441
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.441
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.441
3p67FMNPentaerythritol tetranitrate reductase/0.441
3qfrFMNNADPH--cytochrome P450 reductase/0.441
4c4oNADSADH/0.441
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4fn4NADShort chain dehydrogenase/0.441
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.441
4m4922YL-lactate dehydrogenase A chain1.1.1.270.441
4nv10FXFormyl transferase/0.441
5cflC2EStimulator of interferon genes protein/0.441
1ex75GPGuanylate kinase2.7.4.80.440
1j1zATPArgininosuccinate synthase/0.440
1j49NADD-lactate dehydrogenase1.1.1.280.440
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.440
1rneC60Renin3.4.23.150.440
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.440
2ea2F77Methionine aminopeptidase 2/0.440
2g1s4IGRenin3.4.23.150.440
2gesCOKPantothenate kinase2.7.1.330.440
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2oegUPGUDP-glucose pyrophosphorylase/0.440
2zsaADPPantothenate kinase2.7.1.330.440
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.440
3fhxPXLPyridoxal kinase2.7.1.350.440
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.440
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.440
4araC56Acetylcholinesterase3.1.1.70.440
4b68NAPL-ornithine N(5)-monooxygenase/0.440
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.440
4y9lFADAcyl-CoA dehydrogenase family member 11/0.440
5czySAMEukaryotic huntingtin interacting protein B/0.440