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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2e16SAHDiphthine synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2e16SAHDiphthine synthase/1.000
2en5SAHDiphthine synthase/0.814
2pb4SAHDiphthine synthase/0.813
2eglSAHDiphthine synthase/0.812
2dekSAHDiphthine synthase/0.792
2ek7SAHDiphthine synthase/0.789
2owvSAHDiphthine synthase/0.776
2p6lSAHDiphthine synthase/0.760
2e8qSAHDiphthine synthase/0.759
2pcmSAHDiphthine synthase/0.750
2emuSAHDiphthine synthase/0.749
2pb6SAHDiphthine synthase/0.734
2dxvSAHDiphthine synthase/0.733
2e8hSAHDiphthine synthase/0.731
2e8sSAHDiphthine synthase/0.725
2dxwSAHDiphthine synthase/0.720
2eh5SAHDiphthine synthase/0.720
2emrSAHDiphthine synthase/0.713
2p6dSAHDiphthine synthase/0.711
2dsgSAHDiphthine synthase/0.703
2ehlSAHDiphthine synthase/0.697
2p6kSAHDiphthine synthase/0.692
2ek4SAHDiphthine synthase/0.688
2huxSAHDiphthine synthase/0.686
1vceSAHDiphthine synthase/0.682
2hr8SAHDiphthine synthase/0.681
2owkSAHDiphthine synthase/0.680
2pchSAHDiphthine synthase/0.679
2ejjSAHDiphthine synthase/0.672
2egsSAHDiphthine synthase/0.671
2ed5SAHDiphthine synthase/0.670
2ejkSAHDiphthine synthase/0.670
2el0SAHDiphthine synthase/0.667
2eniSAHDiphthine synthase/0.667
2e08SAHDiphthine synthase/0.666
2egbSAHDiphthine synthase/0.660
2dv3SAHDiphthine synthase/0.653
2eh2SAHDiphthine synthase/0.652
2ekaSAHDiphthine synthase/0.651
2p2xSAHDiphthine synthase/0.651
2e4nSAHDiphthine synthase/0.650
2dv7SAHDiphthine synthase/0.647
2dv4SAHDiphthine synthase/0.646
2el3SAHDiphthine synthase/0.644
2owuSAHDiphthine synthase/0.640
2dshSAHDiphthine synthase/0.638
2eleSAHDiphthine synthase/0.634
2pcgSAHDiphthine synthase/0.634
2eldSAHDiphthine synthase/0.632
2ek2SAHDiphthine synthase/0.630
1wngSAHDiphthine synthase/0.629
2pciSAHDiphthine synthase/0.626
2e17SAHDiphthine synthase/0.625
2e07SAHDiphthine synthase/0.624
2eeqSAHDiphthine synthase/0.624
2e7rSAHDiphthine synthase/0.614
2p5fSAHDiphthine synthase/0.607
2z6rSAHDiphthine synthase/0.607
2pcaSAHDiphthine synthase/0.604
2pckSAHDiphthine synthase/0.603
2huvSAHDiphthine synthase/0.601
2ed3SAHDiphthine synthase/0.600
2p5cSAHDiphthine synthase/0.599
2e8rSAHDiphthine synthase/0.597
2ejzSAHDiphthine synthase/0.597
2e15SAHDiphthine synthase/0.596
2dsiSAHDiphthine synthase/0.591
2owfSAHDiphthine synthase/0.584
2dxxSAHDiphthine synthase/0.575
2pb5SAHDiphthine synthase/0.575
2owgSAHDiphthine synthase/0.569
2p6iSAHDiphthine synthase/0.569
2dv5SAHDiphthine synthase/0.567
2eh4SAHDiphthine synthase/0.566
2huqSAHDiphthine synthase/0.563
2hutSAHDiphthine synthase/0.562
2p9dSAHDiphthine synthase/0.552
2ek3SAHDiphthine synthase/0.545
1xe55FEPlasmepsin-23.4.23.390.523
4g3jVNTLanosterol 14-alpha-demethylase/0.513
2ifaFMNUncharacterized protein/0.501
4g7gVFVLanosterol 14-alpha-demethylase/0.499
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.498
1w6hTITPlasmepsin-23.4.23.390.495
1lbcCYZGlutamate receptor 2/0.494
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.492
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.490
5hwsNAP2-dehydropantoate 2-reductase/0.490
2q5g1FAPeroxisome proliferator-activated receptor delta/0.489
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.489
1x1aSAMC-20 methyltransferase/0.485
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.484
4ji91M3Tyrosine-protein kinase JAK2/0.484
2he5NDPAldo-keto reductase family 1 member C211.1.10.482
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.482
2x06NADL-sulfolactate dehydrogenase/0.482
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.482
3uylTYDProbable NDP-rhamnosyltransferase/0.482
4q71FADBifunctional protein PutA/0.482
3a3gDLZLumazine protein/0.481
3gw9VNILanosterol 14-alpha-demethylase/0.481
4h3f10OBeta-secretase 13.4.23.460.481
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.480
3ig6438Urokinase-type plasminogen activator3.4.21.730.480
2a94AP0L-lactate dehydrogenase1.1.1.270.478
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
1x1dSAHC-20 methyltransferase/0.477
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.477
4h3j10WBeta-secretase 13.4.23.460.477
3lpjZ75Beta-secretase 13.4.23.460.476
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.476
3u9eCOALmo1369 protein/0.476
4a8v2ANMajor pollen allergen Bet v 1-J/0.476
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.476
1bim0QBRenin3.4.23.150.475
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.475
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
1gaqFADFerredoxin/0.474
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.474
2iyfERYOleandomycin glycosyltransferase2.4.10.474
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.474
4i1iNADMalate dehydrogenase/0.474
3ijoB4DGlutamate receptor 2/0.473
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.473
1f8wFADNADH peroxidase1.11.1.10.472
4djy0KRBeta-secretase 13.4.23.460.472
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.472
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.471
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.471
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.471
4dh60KNBeta-secretase 13.4.23.460.471
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.471
1uzwCDHIsopenicillin N synthase1.21.3.10.470
3b70NAPEnoyl reductase LovC10.470
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1msmJE2Gag-Pol polyprotein3.4.23.160.469
1x1cSAHC-20 methyltransferase/0.469
2rcyNAPPyrroline-5-carboxylate reductase/0.469
2xhd7T9Glutamate receptor 2/0.469
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.469
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.469
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.469
1tqf32PBeta-secretase 13.4.23.460.468
1xvaSAMGlycine N-methyltransferase2.1.1.200.468
3a1nNADNDP-sugar epimerase/0.468
3clxX22E3 ubiquitin-protein ligase XIAP6.3.20.468
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3d91REMRenin3.4.23.150.467
3hl0NADMaleylacetate reductase/0.467
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.467
3nsh957Beta-secretase 13.4.23.460.467
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.467
3wagTYDGlycosyltransferase/0.467
4i0i957Beta-secretase 13.4.23.460.467
4irnFADAnaB/0.467
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1me6IVSPlasmepsin-23.4.23.390.466
3zh8C58Protein kinase C iota type2.7.11.130.466
4h3g10QBeta-secretase 13.4.23.460.466
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.466
4wriOKAOkadaic acid binding protein 2-alpha/0.466
5irnADPNucleotide binding oligomerization domain containing 2/0.466
2p5uNADUDP-glucose 4-epimerase/0.465
2p83MR0Beta-secretase 13.4.23.460.465
2q4bNAPUncharacterized protein At5g02240/0.465
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.465
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.465
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.465
4bfzZVZPantothenate kinase2.7.1.330.465
4fxy0W2Neurolysin, mitochondrial3.4.24.160.465
1fy7COAHistone acetyltransferase ESA1/0.464
1juvNDPDihydrofolate reductase1.5.1.30.464
1pd9CO4Dihydrofolate reductase1.5.1.30.464
1xddAAYIntegrin alpha-L/0.464
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.464
2pswCOAN-alpha-acetyltransferase 50/0.464
3c1y2BADNA integrity scanning protein DisA/0.464
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.464
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.464
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
1nhhANPDNA mismatch repair protein MutL/0.463
1xe65FPPlasmepsin-23.4.23.390.463
4wudANPDNA gyrase subunit B/0.463
5dp2NAPCurF/0.463
1g1aNADdTDP-glucose 4,6-dehydratase/0.462
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.462
1y4lSVRBasic phospholipase A2 homolog 2/0.462
2gv8NDPThiol-specific monooxygenase1.14.130.462
3oibFDAPutative acyl-CoA dehydrogenase/0.462
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.461
1ptjNAPNAD(P) transhydrogenase subunit beta1.6.1.20.461
1tehNADAlcohol dehydrogenase class-31.1.1.10.461
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.461
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.461
2iviACWIsopenicillin N synthase1.21.3.10.461
2x7hPFNProstaglandin reductase 310.461
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3ik6HCZGlutamate receptor 2/0.461
3vt8YI3Vitamin D3 receptor/0.461
1bxoPP7Penicillopepsin-13.4.23.200.460
3gqvNAPEnoyl reductase LovC10.460
1bwsNDPGDP-L-fucose synthase/0.459
2ft9CHDFatty acid-binding protein 2, liver/0.459
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.459
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4dbzNDPPutative ketoacyl reductase1.3.10.459
1bil0IURenin3.4.23.150.458
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1g63FMNEpidermin decarboxylase4.1.10.458
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.458
2fonFADAcyl-coenzyme A oxidase/0.458
2yxuATPPyridoxal kinase2.7.1.350.458
3slkNDPPolyketide synthase extender module 2/0.458
3to6LYS_CMCHistone acetyltransferase ESA1/0.458
4b78KGGBeta-secretase 13.4.23.460.458
4eb7PLPCysteine desulfurase IscS 2/0.458
4nbwNADShort-chain dehydrogenase/reductase SDR/0.458
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.458
5jscFADPutative acyl-CoA dehydrogenase/0.458
1bk0ACVIsopenicillin N synthase1.21.3.10.457
1dhrNADDihydropteridine reductase1.5.1.340.457
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.457
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.457
3tjzGNPADP-ribosylation factor 1/0.457
4dfg0JVGag-Pol polyprotein3.4.23.160.457
4frkDWDBeta-secretase 13.4.23.460.457
4ips1G4Mycocyclosin synthase1.14.21.90.457
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.457
1g6kNADGlucose 1-dehydrogenase1.1.1.470.456
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.456
1t2cNAIL-lactate dehydrogenase1.1.1.270.456
1v9aSAHUncharacterized protein/0.456
1xl5190Gag-Pol polyprotein3.4.23.160.456
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.456
2gjlFMNNitronate monooxygenase1.13.12.160.456
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.456
2qbuSAHPrecorrin-2 methyltransferase/0.456
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3q43D66M1 family aminopeptidase3.4.110.456
4fm80UQBeta-secretase 13.4.23.460.456
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1joaFADNADH peroxidase1.11.1.10.455
1phgMYTCamphor 5-monooxygenase1.14.15.10.455
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.455
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.455
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4a83DXCMajor pollen allergen Bet v 1-A/0.455
4y3jHICEndothiapepsin3.4.23.220.455
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.454
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.454
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.454
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.454
2uxoTACHTH-type transcriptional regulator TtgR/0.454
2zsaADPPantothenate kinase2.7.1.330.454
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.454
3lpiZ74Beta-secretase 13.4.23.460.454
3zoiM2WIsopenicillin N synthase1.21.3.10.454
4prvADPDNA gyrase subunit B/0.454
1dr3TAPDihydrofolate reductase1.5.1.30.453
1f8fNADBenzyl alcohol dehydrogenase/0.453
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.453
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.453
1udaUFGUDP-glucose 4-epimerase5.1.3.20.453
1vikBAYGag-Pol polyprotein/0.453
2rlcCHDCholoylglycine hydrolase3.5.1.240.453
2xx91NFGlutamate receptor 2/0.453
3crzFADFerredoxin--NADP+ reductase/0.453
3kkzSAMUncharacterized protein/0.453
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.453
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.453
3vdqNAD3-hydroxybutyrate dehydrogenase/0.453
4acxS8ZBeta-secretase 13.4.23.460.453
4exg916Beta-secretase 13.4.23.460.453
1bxqPP8Penicillopepsin-13.4.23.200.452
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.452
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.452
2dftADPShikimate kinase2.7.1.710.452
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.452
2jb4A14Isopenicillin N synthase1.21.3.10.452
2om9AJAPeroxisome proliferator-activated receptor gamma/0.452
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.452
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.452
3omuIBDHeat shock protein 83/0.452
3orfNADDihydropteridine reductase1.5.1.340.452
3pqbVGPPutative oxidoreductase/0.452
3sf6FDAGlutaryl-CoA dehydrogenase/0.452
3v0p4GWHisto-blood group ABO system transferase/0.452
4lxk1YTBeta-secretase 13.4.23.460.452
4wucANPDNA gyrase subunit B/0.452
4xguADPPutative pachytene checkpoint protein 2/0.452
4xgxADPFAD:protein FMN transferase/0.452
1dirNADDihydropteridine reductase1.5.1.340.451
1gqtACPRibokinase/0.451
2bjfDXCCholoylglycine hydrolase3.5.1.240.451
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.451
2viyVG3Beta-secretase 13.4.23.460.451
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3jv7NADSecondary alcohol dehydrogenase/0.451
4a862ANMajor pollen allergen Bet v 1-A/0.451
4egbNADdTDP-glucose 4,6-dehydratase/0.451
4j0v1H7Beta-secretase 13.4.23.460.451
4m83ERYOleandomycin glycosyltransferase2.4.10.451
4n9iPCGCatabolite expression activator/0.451
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.451
5cyoGDPSeptin-9/0.451
1hbvGANGag-Pol polyprotein/0.450
1qy5NECEndoplasmin/0.450
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.450
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.450
1xs7MMIBeta-secretase 13.4.23.460.450
2ebaFADPutative glutaryl-CoA dehydrogenase/0.450
2gpjFADSiderophore-interacting protein/0.450
2wedPP6Penicillopepsin-13.4.23.200.450
2y0mACOHistone acetyltransferase KAT8/0.450
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3k5gBJCBeta-secretase 13.4.23.460.450
3kxw1ZZSaframycin Mx1 synthetase B/0.450
3s5wFADL-ornithine N(5)-monooxygenase/0.450
3sdkP3NProteasome subunit beta type-53.4.25.10.450
3sdkP3NProteasome subunit beta type-63.4.25.10.450
4b7754MBeta-secretase 13.4.23.460.450
4ejvLCLTranscriptional regulator TcaR/0.450
4lcjNADC-terminal-binding protein 2/0.450
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
5af7FADAcyl-CoA dehydrogenase/0.450
2a5kAZPReplicase polyprotein 1ab3.4.220.449
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.449
3tneRITCandidapepsin-13.4.23.240.449
4dzzADPPlasmid partitioning protein ParF/0.449
4yaoFMNNADPH--cytochrome P450 reductase/0.449
1beuIPLTryptophan synthase alpha chain/0.448
1fm4DXCMajor pollen allergen Bet v 1-L/0.448
1lf3EH5Plasmepsin-23.4.23.390.448
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1yqzCOACoenzyme A disulfide reductase/0.448
2fznFADBifunctional protein PutA1.5.5.20.448
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.448
2ym1FADPhenylacetone monooxygenase1.14.13.920.448
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.448
2ztsADPUncharacterized protein/0.448
3ensENSCoagulation factor X3.4.21.60.448
3uayADNPurine nucleoside phosphorylase DeoD-type/0.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1npvL27Gag-Pol polyprotein3.4.23.160.447
1qvuPRLHTH-type transcriptional regulator QacR/0.447
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
2cftPLPPyridoxal phosphate phosphatase/0.447
2g8yNADHydroxycarboxylate dehydrogenase B/0.447
2oapANPType II secretion system protein (GspE-2)/0.447
2znpK55Peroxisome proliferator-activated receptor delta/0.447
3dv5BAVBeta-secretase 13.4.23.460.447
3in6FMNUncharacterized protein/0.447
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.447
3tdj3TJGlutamate receptor 2/0.447
4ambDUDPutative glycosyl transferase/0.447
4gl4NAIAlcohol dehydrogenase class-3/0.447
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.447
1ay0TPPTransketolase 12.2.1.10.446
1e3eNAIAlcohol dehydrogenase 41.1.1.10.446
1kkq471Peroxisome proliferator-activated receptor alpha/0.446
1tj0FADBifunctional protein PutA1.5.5.20.446
1u3cFADCryptochrome-1/0.446
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.446
2g1o2IGRenin3.4.23.150.446
2gz8F3FOrf1a polyprotein/0.446
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.446
2vwqNAPGlucose 1-dehydrogenase/0.446
2wecPP5Penicillopepsin-13.4.23.200.446
2xlrFADPutative flavin-containing monooxygenase/0.446
3bc3OPTCathepsin L13.4.22.150.446
3nutSAHPrecorrin-3 methylase/0.446
3r83Z14Cyclin-dependent kinase 22.7.11.220.446
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.446
4bfxZVXPantothenate kinase2.7.1.330.446
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.446
4q0kGA3Phytohormone-binding protein/0.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.446
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1f20FADNitric oxide synthase, brain1.14.13.390.445
1p9wANPType II secretion system protein E/0.445
1x1bSAHC-20 methyltransferase/0.445
2b7aIZATyrosine-protein kinase JAK2/0.445
2cv2GSUGlutamate--tRNA ligase6.1.1.170.445
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.445
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.445
2ou2ACOHistone acetyltransferase KAT5/0.445
2zvcSAHPrecorrin-3 C17-methyltransferase/0.445
3pftFMNFlavin reductase/0.445
3vqsJT1Genome polyprotein/0.445
4f5yC2EStimulator of interferon genes protein/0.445
4yxm2BADNA integrity scanning protein DisA/0.445
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.444
2aa3AP0L-lactate dehydrogenase/0.444
3cic316Beta-secretase 13.4.23.460.444
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.444
3ieuGDPGTPase Era/0.444
3ivcFG4Pantothenate synthetase6.3.2.10.444
3jzdNADMaleylacetate reductase/0.444
3lpkZ76Beta-secretase 13.4.23.460.444
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.444
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
3v3m0ENReplicase polyprotein 1a3.4.19.120.444
4a81DXCMajor pollen allergen Bet v 1-A/0.444
4dpf0LGBeta-secretase 13.4.23.460.444
4dptAGSMevalonate diphosphate decarboxylase/0.444
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.444
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.444
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.444
4friDWABeta-secretase 13.4.23.460.444
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.444
4ipw1G7Mycocyclosin synthase1.14.21.90.444
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.444
5a3bAPRSIR2 family protein/0.444
1bmfANPATP synthase subunit alpha, mitochondrial/0.443
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.443
1hb1OCVIsopenicillin N synthase1.21.3.10.443
1pjcNADAlanine dehydrogenase/0.443
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.443
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.443
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.443
2zjmF1MBeta-secretase 13.4.23.460.443
3cid318Beta-secretase 13.4.23.460.443
3ihgVAKAklavinone 12-hydroxylase RdmE/0.443
3lqfNADGalactitol dehydrogenase/0.443
3zuyTCHTransporter/0.443
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.443
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.443
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.443
4ohvANPProtein clpf-1/0.443
4qxq1YEStimulator of interferon genes protein/0.443
1ep3FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.442
1nzfUPGDNA beta-glucosyltransferase/0.442
1qiqACCIsopenicillin N synthase1.21.3.10.442
1vbiNADMalate/L-lactate dehydrogenase family protein/0.442
1zk7FADMercuric reductase1.16.1.10.442
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.442
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
3bnkFMNFlavoredoxin/0.442
3d4pNADL-lactate dehydrogenase 11.1.1.270.442
3i0pNADMalate dehydrogenase, putative/0.442
3iocA5DPantothenate synthetase6.3.2.10.442
3kgcLY7Glutamate receptor 2/0.442
3w8eNAD3-hydroxybutyrate dehydrogenase/0.442
4a7b3W5Collagenase 33.4.240.442
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.442
4i8zG08Gag-Pol polyprotein3.4.23.160.442
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.442
5d3qGDPDynamin-13.6.5.50.442
1bdmNAXMalate dehydrogenase/0.441
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1kp2ATPArgininosuccinate synthase6.3.4.50.441
1obbNADAlpha-glucosidase3.2.1.200.441
1rneC60Renin3.4.23.150.441
2b53D23Cyclin-dependent kinase 22.7.11.220.441
2bu9HFVIsopenicillin N synthase1.21.3.10.441
2c29NAPDihydroflavonol 4-reductase/0.441
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.441
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.441
2npaMMBPeroxisome proliferator-activated receptor alpha/0.441
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.441
2rhgIGPTryptophan synthase alpha chain/0.441
2rkvZBATrichothecene 3-O-acetyltransferase/0.441
3c212BADNA integrity scanning protein DisA/0.441
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.441
3jziJZLBiotin carboxylase6.3.4.140.441
3nw3MU2Peptidoglycan recognition protein 1/0.441
3nwxKVSGag-Pol polyprotein3.4.23.160.441
3sdi3SDProteasome subunit beta type-53.4.25.10.441
3sdi3SDProteasome subunit beta type-63.4.25.10.441
3t3c017Gag-Pol polyprotein3.4.23.160.441
3toxNAPPutative oxidoreductase/0.441
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
3w5uFADFerredoxin/0.441
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.441
4gxs0YSGlutamate receptor 2/0.441
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.441
4tuvCPZCytochrome P450 1191.140.441
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.440
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.440
1cf3FADGlucose oxidase1.1.3.40.440
1cjtFOKAdenylate cyclase type 2/0.440
1cjtFOKAdenylate cyclase type 5/0.440
1h8hATPATP synthase subunit alpha, mitochondrial/0.440
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.440
1ipeNDPTropinone reductase 21.1.1.2360.440
1jedADPSulfate adenylyltransferase/0.440
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.440
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.440
2cjfRP43-dehydroquinate dehydratase4.2.1.100.440
2hm1LIQBeta-secretase 13.4.23.460.440
2qenADPWalker-Type ATPase/0.440
2y3sTIRTamL/0.440
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
2z54AB1Gag-Pol polyprotein3.4.23.160.440
2znq401Peroxisome proliferator-activated receptor delta/0.440
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
3h6vNS6Glutamate receptor 2/0.440
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.440
3oev3OEProteasome subunit beta type-53.4.25.10.440
3oev3OEProteasome subunit beta type-63.4.25.10.440
3owaFADAcyl-CoA dehydrogenase/0.440
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.440
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.440
3wb2YGPUncharacterized protein MJ0488/0.440
3zkyWT4Isopenicillin N synthase1.21.3.10.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440
4ktc1X3Genome polyprotein3.4.21.980.440
4xumIMNPeroxisome proliferator-activated receptor gamma/0.440
4zj8SUVOrexin receptor type 1/0.440