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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2dshSAHDiphthine synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2dshSAHDiphthine synthase/1.000
2eh4SAHDiphthine synthase/0.786
2ejjSAHDiphthine synthase/0.780
2e07SAHDiphthine synthase/0.778
2pckSAHDiphthine synthase/0.775
2huqSAHDiphthine synthase/0.767
2p9dSAHDiphthine synthase/0.752
2dxxSAHDiphthine synthase/0.732
2e08SAHDiphthine synthase/0.732
2pb5SAHDiphthine synthase/0.732
2p6iSAHDiphthine synthase/0.728
2pcaSAHDiphthine synthase/0.728
1wngSAHDiphthine synthase/0.717
2owgSAHDiphthine synthase/0.712
2egbSAHDiphthine synthase/0.701
2dv3SAHDiphthine synthase/0.699
2ed3SAHDiphthine synthase/0.699
2owuSAHDiphthine synthase/0.698
2e15SAHDiphthine synthase/0.697
2p6lSAHDiphthine synthase/0.694
2huvSAHDiphthine synthase/0.691
2p5cSAHDiphthine synthase/0.690
2dv5SAHDiphthine synthase/0.687
2eeqSAHDiphthine synthase/0.684
2e7rSAHDiphthine synthase/0.681
2dv4SAHDiphthine synthase/0.668
2hr8SAHDiphthine synthase/0.662
1vceSAHDiphthine synthase/0.659
2pchSAHDiphthine synthase/0.656
2p5fSAHDiphthine synthase/0.649
2ek3SAHDiphthine synthase/0.648
2e4nSAHDiphthine synthase/0.645
2z6rSAHDiphthine synthase/0.644
2eldSAHDiphthine synthase/0.643
2e8hSAHDiphthine synthase/0.642
2e16SAHDiphthine synthase/0.639
2huxSAHDiphthine synthase/0.639
2egsSAHDiphthine synthase/0.638
2pciSAHDiphthine synthase/0.638
2dekSAHDiphthine synthase/0.635
2pcgSAHDiphthine synthase/0.634
2owvSAHDiphthine synthase/0.629
2dsiSAHDiphthine synthase/0.628
2e17SAHDiphthine synthase/0.628
2eglSAHDiphthine synthase/0.620
2p2xSAHDiphthine synthase/0.616
2hutSAHDiphthine synthase/0.614
2e8rSAHDiphthine synthase/0.611
2el0SAHDiphthine synthase/0.610
2el3SAHDiphthine synthase/0.609
2dsgSAHDiphthine synthase/0.608
2dv7SAHDiphthine synthase/0.605
2p6kSAHDiphthine synthase/0.601
2en5SAHDiphthine synthase/0.596
2ejkSAHDiphthine synthase/0.595
2ejzSAHDiphthine synthase/0.594
2eniSAHDiphthine synthase/0.588
2ed5SAHDiphthine synthase/0.586
2pb6SAHDiphthine synthase/0.584
2ek7SAHDiphthine synthase/0.581
2e8qSAHDiphthine synthase/0.580
2ekaSAHDiphthine synthase/0.580
2ek2SAHDiphthine synthase/0.579
2pb4SAHDiphthine synthase/0.579
2owfSAHDiphthine synthase/0.573
2dxwSAHDiphthine synthase/0.566
2eleSAHDiphthine synthase/0.564
2owkSAHDiphthine synthase/0.560
2ek4SAHDiphthine synthase/0.559
2p6dSAHDiphthine synthase/0.558
2dxvSAHDiphthine synthase/0.553
2eh2SAHDiphthine synthase/0.538
2eh5SAHDiphthine synthase/0.538
2emuSAHDiphthine synthase/0.530
2e8sSAHDiphthine synthase/0.528
2emrSAHDiphthine synthase/0.522
2pcmSAHDiphthine synthase/0.520
2ehlSAHDiphthine synthase/0.517
3nutSAHPrecorrin-3 methylase/0.500
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.496
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.496
4g7gVFVLanosterol 14-alpha-demethylase/0.495
1x1aSAMC-20 methyltransferase/0.490
2givACOHistone acetyltransferase KAT8/0.490
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.486
3gw9VNILanosterol 14-alpha-demethylase/0.486
5c77SAHProtein arginine N-methyltransferase SFM1/0.485
4h3j10WBeta-secretase 13.4.23.460.483
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.482
3uylTYDProbable NDP-rhamnosyltransferase/0.482
4djy0KRBeta-secretase 13.4.23.460.482
1pjcNADAlanine dehydrogenase/0.480
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.480
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
2ou2ACOHistone acetyltransferase KAT5/0.479
4g3jVNTLanosterol 14-alpha-demethylase/0.479
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.478
2ifaFMNUncharacterized protein/0.476
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.475
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.474
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
1pd9CO4Dihydrofolate reductase1.5.1.30.473
2pswCOAN-alpha-acetyltransferase 50/0.473
2vbdV10Isopenicillin N synthase1.21.3.10.472
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.471
2b7aIZATyrosine-protein kinase JAK2/0.470
3zh8C58Protein kinase C iota type2.7.11.130.470
4h3f10OBeta-secretase 13.4.23.460.470
5dp2NAPCurF/0.470
1xddAAYIntegrin alpha-L/0.469
4oztP1AEcdysone receptor, putative/0.469
2qbuSAHPrecorrin-2 methyltransferase/0.468
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.468
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.468
3sdkP3NProteasome subunit beta type-53.4.25.10.467
3sdkP3NProteasome subunit beta type-63.4.25.10.467
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.467
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.466
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.466
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.466
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3lqfNADGalactitol dehydrogenase/0.466
4irnFADAnaB/0.466
1obnASVIsopenicillin N synthase1.21.3.10.465
4ambDUDPutative glycosyl transferase/0.465
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
5jscFADPutative acyl-CoA dehydrogenase/0.465
1kp3ATPArgininosuccinate synthase6.3.4.50.464
2w3bNDPDihydrofolate reductase1.5.1.30.464
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.464
1bim0QBRenin3.4.23.150.463
1dirNADDihydropteridine reductase1.5.1.340.463
3lpiZ74Beta-secretase 13.4.23.460.463
3to6LYS_CMCHistone acetyltransferase ESA1/0.463
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.463
3vdqNAD3-hydroxybutyrate dehydrogenase/0.463
4acxS8ZBeta-secretase 13.4.23.460.463
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.463
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.462
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.462
2xhd7T9Glutamate receptor 2/0.462
3iaeD7KBenzaldehyde lyase/0.462
3zoiM2WIsopenicillin N synthase1.21.3.10.462
4a83DXCMajor pollen allergen Bet v 1-A/0.462
4eb7PLPCysteine desulfurase IscS 2/0.462
1g63FMNEpidermin decarboxylase4.1.10.461
3f3sNADLambda-crystallin homolog/0.461
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.461
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.461
4q71FADBifunctional protein PutA/0.461
4wudANPDNA gyrase subunit B/0.461
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.461
1e79ATPATP synthase subunit alpha, mitochondrial/0.460
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.460
1rneC60Renin3.4.23.150.460
2iviACWIsopenicillin N synthase1.21.3.10.460
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.460
3hl0NADMaleylacetate reductase/0.460
3ijoB4DGlutamate receptor 2/0.460
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.460
1mjbACOHistone acetyltransferase ESA1/0.459
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.459
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.459
1lbcCYZGlutamate receptor 2/0.458
1v9aSAHUncharacterized protein/0.458
1xe55FEPlasmepsin-23.4.23.390.458
2a94AP0L-lactate dehydrogenase1.1.1.270.458
2he5NDPAldo-keto reductase family 1 member C211.1.10.458
3ig6438Urokinase-type plasminogen activator3.4.21.730.458
3lpjZ75Beta-secretase 13.4.23.460.458
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.458
3u9eCOALmo1369 protein/0.458
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.458
1t2cNAIL-lactate dehydrogenase1.1.1.270.457
2c29NAPDihydroflavonol 4-reductase/0.457
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.457
2jb4A14Isopenicillin N synthase1.21.3.10.457
2y0mACOHistone acetyltransferase KAT8/0.457
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.457
2y3sTIRTamL/0.457
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.457
1mp0NADAlcohol dehydrogenase class-31.1.1.10.456
2bu9HFVIsopenicillin N synthase1.21.3.10.456
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.456
3dm6757Beta-secretase 13.4.23.460.456
3h2sNDPPutative NADH-flavin reductase/0.456
3slkNDPPolyketide synthase extender module 2/0.456
4m83ERYOleandomycin glycosyltransferase2.4.10.456
4yagNAIC alpha-dehydrogenase/0.456
5hwsNAP2-dehydropantoate 2-reductase/0.456
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.455
1o97FADElectron transfer flavoprotein subunit alpha/0.455
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
2p83MR0Beta-secretase 13.4.23.460.455
2y60M8FIsopenicillin N synthase1.21.3.10.455
3bnkFMNFlavoredoxin/0.455
3sf6FDAGlutaryl-CoA dehydrogenase/0.455
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.455
1bk0ACVIsopenicillin N synthase1.21.3.10.454
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.454
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.454
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.454
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.454
4xguADPPutative pachytene checkpoint protein 2/0.454
1zeoC01Peroxisome proliferator-activated receptor gamma/0.453
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.453
2rcyNAPPyrroline-5-carboxylate reductase/0.453
2v7qATPATP synthase subunit alpha, mitochondrial/0.453
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.453
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3r9uFADThioredoxin reductase/0.453
3zkyWT4Isopenicillin N synthase1.21.3.10.453
1f8wFADNADH peroxidase1.11.1.10.452
1g1aNADdTDP-glucose 4,6-dehydratase/0.452
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.452
1x1dSAHC-20 methyltransferase/0.452
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.452
2vkeTACTetracycline repressor protein class D/0.452
3ad9NADSubunit alpha of sarocosine oxidase/0.452
3orfNADDihydropteridine reductase1.5.1.340.452
3ox4NADAlcohol dehydrogenase 21.1.1.10.452
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.452
3qwbNDPProbable quinone oxidoreductase1.6.5.50.452
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.452
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.452
4wriOKAOkadaic acid binding protein 2-alpha/0.452
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1drhNAPDihydrofolate reductase1.5.1.30.451
2oapANPType II secretion system protein (GspE-2)/0.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
3bg7FADPyranose 2-oxidase/0.451
3br3ETHTH-type transcriptional regulator QacR/0.451
3lpkZ76Beta-secretase 13.4.23.460.451
3qlrNDPDihydrofolate reductase1.5.1.30.451
3qlsNDPDihydrofolate reductase1.5.1.30.451
3v0p4GWHisto-blood group ABO system transferase/0.451
3vqsJT1Genome polyprotein/0.451
4gsuDWZL,D-transpeptidase 22.3.20.451
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.450
1e1qANPATP synthase subunit alpha, mitochondrial/0.450
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.450
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.450
1qiqACCIsopenicillin N synthase1.21.3.10.450
1y0s331Peroxisome proliferator-activated receptor delta/0.450
2a92NAIL-lactate dehydrogenase/0.450
2ahrNAPPyrroline-5-carboxylate reductase/0.450
2gjlFMNNitronate monooxygenase1.13.12.160.450
2gv8NDPThiol-specific monooxygenase1.14.130.450
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.450
2xx91NFGlutamate receptor 2/0.450
2y65ADPKinesin heavy chain/0.450
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.450
4hwkNAPSepiapterin reductase1.1.1.1530.450
4j4nD44Peptidylprolyl isomerase/0.450
4nbwNADShort-chain dehydrogenase/reductase SDR/0.450
4wucANPDNA gyrase subunit B/0.450
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.450
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.449
2il2LIXRenin3.4.23.150.449
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.449
2xlrFADPutative flavin-containing monooxygenase/0.449
3ojxFADNADPH--cytochrome P450 reductase/0.449
4yaiNAIC alpha-dehydrogenase/0.449
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.448
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
2ebaFADPutative glutaryl-CoA dehydrogenase/0.448
2ft0ACOdTDP-fucosamine acetyltransferase/0.448
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.448
2p5uNADUDP-glucose 4-epimerase/0.448
2wedPP6Penicillopepsin-13.4.23.200.448
2x7hPFNProstaglandin reductase 310.448
2y6fM9FIsopenicillin N synthase1.21.3.10.448
3a1nNADNDP-sugar epimerase/0.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.448
3uceNDPDehydrogenase/0.448
3wqmB29Diterpene synthase3.1.7.80.448
4bfzZVZPantothenate kinase2.7.1.330.448
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.448
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.448
4frkDWDBeta-secretase 13.4.23.460.448
4gl4NAIAlcohol dehydrogenase class-3/0.448
4i8zG08Gag-Pol polyprotein3.4.23.160.448
4relKMPGlycosyltransferase/0.448
1fm4DXCMajor pollen allergen Bet v 1-L/0.447
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.447
1x1bSAHC-20 methyltransferase/0.447
1x1cSAHC-20 methyltransferase/0.447
1y4lSVRBasic phospholipase A2 homolog 2/0.447
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.447
2eklNADD-3-phosphoglycerate dehydrogenase/0.447
2x9dITCTetracycline repressor protein class D/0.447
2xpuTDCTetracycline repressor protein class D/0.447
2yxuATPPyridoxal kinase2.7.1.350.447
3b6zCO7Enoyl reductase LovC10.447
3cic316Beta-secretase 13.4.23.460.447
3ik6HCZGlutamate receptor 2/0.447
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.447
4dbzNDPPutative ketoacyl reductase1.3.10.447
4dh60KNBeta-secretase 13.4.23.460.447
4dzzADPPlasmid partitioning protein ParF/0.447
4twnB96Ephrin type-A receptor 32.7.10.10.447
4yntFDAGlucose oxidase, putative/0.447
5f8eSAHPossible transcriptional regulatory protein/0.447
1f8fNADBenzyl alcohol dehydrogenase/0.446
1kkq471Peroxisome proliferator-activated receptor alpha/0.446
1mj9COAHistone acetyltransferase ESA1/0.446
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.446
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.446
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.446
3adaNADSubunit alpha of sarocosine oxidase/0.446
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.446
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.446
3v2uATPProtein GAL3/0.446
4dpf0LGBeta-secretase 13.4.23.460.446
4j7uNAPSepiapterin reductase1.1.1.1530.446
4j7xNAPSepiapterin reductase1.1.1.1530.446
4jlj1NMDeoxycytidine kinase2.7.1.740.446
1j1zATPArgininosuccinate synthase/0.445
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.445
1xs7MMIBeta-secretase 13.4.23.460.445
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.445
2gz7D3FOrf1a polyprotein/0.445
2oegUPGUDP-glucose pyrophosphorylase/0.445
2q4bNAPUncharacterized protein At5g02240/0.445
2xlpFADPutative flavin-containing monooxygenase/0.445
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.445
3ai2NDPNADPH-sorbose reductase/0.445
3gwfNAPCyclohexanone monooxygenase/0.445
4xgiNADGlutamate dehydrogenase/0.445
1g6kNADGlucose 1-dehydrogenase1.1.1.470.444
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1qorNDPQuinone oxidoreductase 1/0.444
1udaUFGUDP-glucose 4-epimerase5.1.3.20.444
1w6hTITPlasmepsin-23.4.23.390.444
1xvaSAMGlycine N-methyltransferase2.1.1.200.444
2c12FADNitroalkane oxidase1.7.3.10.444
2g94ZPQBeta-secretase 13.4.23.460.444
2ikuLIYRenin3.4.23.150.444
2omeNADC-terminal-binding protein 2/0.444
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.444
2y05NAPProstaglandin reductase 1/0.444
3gqvNAPEnoyl reductase LovC10.444
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.444
3ohh3HHBeta-secretase 13.4.23.460.444
3phiNDPShikimate dehydrogenase (NADP(+))/0.444
3r83Z14Cyclin-dependent kinase 22.7.11.220.444
4b78KGGBeta-secretase 13.4.23.460.444
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.444
1e7qNAPGDP-L-fucose synthase/0.443
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1tqf32PBeta-secretase 13.4.23.460.443
1uzwCDHIsopenicillin N synthase1.21.3.10.443
2c20NADUDP-glucose 4-epimerase/0.443
2cftPLPPyridoxal phosphate phosphatase/0.443
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.443
2ft9CHDFatty acid-binding protein 2, liver/0.443
2fznFADBifunctional protein PutA1.5.5.20.443
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.443
3a3gDLZLumazine protein/0.443
3eksCY9Actin-5C/0.443
3em3478Gag-Pol polyprotein3.4.23.160.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
3oqfS51Renin3.4.23.150.443
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.443
3w8eNAD3-hydroxybutyrate dehydrogenase/0.443
4d89BXDBeta-secretase 13.4.23.460.443
4ejmNAPPutative zinc-binding dehydrogenase/0.443
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.443
4wecNADShort chain dehydrogenase/0.443
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.442
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.442
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1me6IVSPlasmepsin-23.4.23.390.442
1phgMYTCamphor 5-monooxygenase1.14.15.10.442
1ptjNAPNAD(P) transhydrogenase subunit beta1.6.1.20.442
1qjfACSIsopenicillin N synthase1.21.3.10.442
1w4zNAPPutative ketoacyl reductase1.3.10.442
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.442
2g8yNADHydroxycarboxylate dehydrogenase B/0.442
2q5g1FAPeroxisome proliferator-activated receptor delta/0.442
2zjmF1MBeta-secretase 13.4.23.460.442
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.442
3fpzAHZThiamine thiazole synthase/0.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4b79NADProbable short-chain dehydrogenase/0.442
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.442
4h3g10QBeta-secretase 13.4.23.460.442
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.442
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.442
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.442
4q0kGA3Phytohormone-binding protein/0.442
4qxr1YEStimulator of interferon genes protein/0.442
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.442
1fmlRTLRetinol dehydratase/0.441
1hkuNADC-terminal-binding protein 11.1.10.441
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.441
1tehNADAlcohol dehydrogenase class-31.1.1.10.441
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.441
2f3eAXQBeta-secretase 13.4.23.460.441
2g1o2IGRenin3.4.23.150.441
2rlcCHDCholoylglycine hydrolase3.5.1.240.441
2wo7ASVIsopenicillin N synthase1.21.3.10.441
2y3rTRKTamL/0.441
2zvcSAHPrecorrin-3 C17-methyltransferase/0.441
3b70NAPEnoyl reductase LovC10.441
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3ieuGDPGTPase Era/0.441
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.441
4enhFVXCholesterol 24-hydroxylase/0.441
5af7FADAcyl-CoA dehydrogenase/0.441
1dhrNADDihydropteridine reductase1.5.1.340.440
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1lf2R37Plasmepsin-23.4.23.390.440
1qyvNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1tj2FADBifunctional protein PutA1.5.5.20.440
1xe65FPPlasmepsin-23.4.23.390.440
2b3dFADModulator of drug activity B/0.440
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.440
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2vijC44Beta-secretase 13.4.23.460.440
2y4gTIRTamL/0.440
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.440
3ggoNAIPrephenate dehydrogenase/0.440
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
3oev3OEProteasome subunit beta type-53.4.25.10.440
3oev3OEProteasome subunit beta type-63.4.25.10.440
3owaFADAcyl-CoA dehydrogenase/0.440
3sxjSAMPutative methyltransferase/0.440
3tr05GPGuanylate kinase/0.440
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.440
4bfxZVXPantothenate kinase2.7.1.330.440
4dxd9PCCell division protein FtsZ/0.440
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.440
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.440
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440