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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1wbvLI3Mitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1wbvLI3Mitogen-activated protein kinase 14/1.000
1wbsLI2Mitogen-activated protein kinase 14/0.795
1wbtWBTMitogen-activated protein kinase 14/0.722
1kv2B96Mitogen-activated protein kinase 14/0.627
2yisYISMitogen-activated protein kinase 14/0.614
3p7bP7BMitogen-activated protein kinase 14/0.598
3hv71AUMitogen-activated protein kinase 14/0.594
1kv1BMUMitogen-activated protein kinase 14/0.589
2puuG2GMitogen-activated protein kinase 14/0.586
3d83GK6Mitogen-activated protein kinase 14/0.575
3nnuEDBMitogen-activated protein kinase 14/0.571
2yiwYIWMitogen-activated protein kinase 14/0.570
3p78P78Mitogen-activated protein kinase 14/0.570
3uvr06FMitogen-activated protein kinase 14/0.569
3hv6R39Mitogen-activated protein kinase 14/0.568
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.568
3k3jF4CMitogen-activated protein kinase 14/0.566
3p5kP5KMitogen-activated protein kinase 14/0.564
3hv4L51Mitogen-activated protein kinase 14/0.561
3nnxEDDMitogen-activated protein kinase 14/0.555
1wbnL09Mitogen-activated protein kinase 14/0.553
3p7cP7CMitogen-activated protein kinase 14/0.545
3p79P79Mitogen-activated protein kinase 14/0.544
3p7aP7AMitogen-activated protein kinase 14/0.542
3lfbZ87Mitogen-activated protein kinase 14/0.541
3nnwEDDMitogen-activated protein kinase 14/0.540
3gi3B10Mitogen-activated protein kinase 14/0.539
3gcuR48Mitogen-activated protein kinase 14/0.538
5hidB1ESerine/threonine-protein kinase B-raf2.7.11.10.538
3npcB96Mitogen-activated protein kinase 92.7.11.240.533
3vhe42QVascular endothelial growth factor receptor 22.7.10.10.524
4aa0AA0Mitogen-activated protein kinase 14/0.522
3hv5R24Mitogen-activated protein kinase 14/0.518
4o2z046Mitogen-activated protein kinase/0.518
3e9319BMitogen-activated protein kinase 14/0.517
1w82L10Mitogen-activated protein kinase 14/0.507
3o8uBMUMitogen-activated protein kinase 14/0.507
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
3cs9NILTyrosine-protein kinase ABL12.7.10.20.504
3wzeBAXVascular endothelial growth factor receptor 22.7.10.10.500
3kq7KQ7Mitogen-activated protein kinase 14/0.499
3ugc046Tyrosine-protein kinase JAK2/0.499
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
3rpr25ZCyclin-dependent kinase 22.7.11.220.496
4fkj11KCyclin-dependent kinase 22.7.11.220.492
3gcvSS6Mitogen-activated protein kinase 14/0.491
4l8mF46Mitogen-activated protein kinase 14/0.489
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
3lfnA27Cyclin-dependent kinase 22.7.11.220.487
2e2b406Tyrosine-protein kinase ABL12.7.10.20.485
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.484
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.483
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
4u0i0LIMast/stem cell growth factor receptor Kit2.7.10.10.482
3gu6ADPDeath-associated protein kinase 12.7.11.10.481
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.481
5av4GENDeath-associated protein kinase 12.7.11.10.481
4ic7ANPMitogen-activated protein kinase 72.7.11.240.480
4gncASORegucalcin3.1.1.170.479
3cwkREACellular retinoic acid-binding protein 2/0.478
3igoANPCalmodulin-domain protein kinase 1, putative/0.478
4f7j0SUCyclin-dependent kinase 82.7.11.220.478
1oi9N20Cyclin-dependent kinase 22.7.11.220.477
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.477
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
2jjxATPUridylate kinase/0.475
3i64DNA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.475
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.475
5auvAGIDeath-associated protein kinase 12.7.11.10.475
5av2KMPDeath-associated protein kinase 12.7.11.10.475
1ir3ANPInsulin receptor2.7.10.10.474
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.474
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.474
2vu3LZECyclin-dependent kinase 22.7.11.220.473
1wvySTUDeath-associated protein kinase 12.7.11.10.472
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.472
2csnCKICasein kinase I homolog 12.7.11.10.472
2eb3ANPEpidermal growth factor receptor2.7.10.10.471
3zsh469Mitogen-activated protein kinase 14/0.471
4uuxAPRCinA-like protein/0.471
4wboANWRhodopsin kinase/0.471
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
3nux3NVCyclin-dependent kinase 62.7.11.220.470
3t54ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.470
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4ubsDIFPentalenic acid synthase1.14.15.110.470
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.469
3dfcANPDeath-associated protein kinase 12.7.11.10.469
3gvuSTIAbelson tyrosine-protein kinase 22.7.10.20.469
4ez50RSCyclin-dependent kinase 62.7.11.220.469
3nwyGTPUridylate kinase/0.468
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.467
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3t9aANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.467
3u4uLNHCasein kinase II subunit alpha2.7.11.10.467
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
4ogrADNCyclin-dependent kinase 92.7.11.220.467
5ce3ADPProtein kinase YopO/0.467
1gy3ATPCyclin-dependent kinase 22.7.11.220.466
1meuDMPGag-Pol polyprotein3.4.23.160.466
1t1sCBQ1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.466
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4bebATPType I restriction enzyme EcoR124II R protein3.1.21.30.466
4ccbOFGALK tyrosine kinase receptor2.7.10.10.466
4d4sBI9Focal adhesion kinase 12.7.10.20.466
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.466
3cppCAMCamphor 5-monooxygenase1.14.15.10.465
3tm5SFGUncharacterized protein/0.465
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.465
2vwpNDPGlucose 1-dehydrogenase/0.464
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.464
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.464
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.464
3dogNNNCyclin-dependent kinase 22.7.11.220.464
4bbe3O4Tyrosine-protein kinase JAK2/0.464
3pwhZMAAdenosine receptor A2a/0.464
3qakUKAAdenosine receptor A2a/0.464
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
2p4yC03Peroxisome proliferator-activated receptor gamma/0.463
2r64740Cyclin-dependent kinase 22.7.11.220.463
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.463
3c4wATPRhodopsin kinase/0.463
3s4qNK0Mitogen-activated protein kinase 14/0.463
3uvqFS8Mitogen-activated protein kinase 14/0.463
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.463
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.463
4o701QKBromodomain-containing protein 4/0.463
1e3vDXCSteroid Delta-isomerase5.3.3.10.462
1kl2FONSerine hydroxymethyltransferase/0.462
1sx4ADP60 kDa chaperonin/0.462
2c4g514Cyclin-dependent kinase 22.7.11.220.462
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.462
3ezrEZRCyclin-dependent kinase 22.7.11.220.462
3qa2XNAKetohexokinase/0.462
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.462
3uleC69Actin-related protein 3/0.462
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.462
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1pmn984Mitogen-activated protein kinase 102.7.11.240.461
1zzlTZYMitogen-activated protein kinase 14/0.461
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.461
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.461
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.461
3c50ADPRhodopsin kinase/0.461
3d8vUD1Bifunctional protein GlmU/0.461
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.461
4ki8ADP60 kDa chaperonin/0.461
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.460
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.460
1vyzN5BCyclin-dependent kinase 22.7.11.220.460
2ckeIQUDeath-associated protein kinase 2/0.460
2ijmADPFocal adhesion kinase 12.7.10.20.460
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2uzlC94Cyclin-dependent kinase 22.7.11.220.460
3i0rRT3Gag-Pol polyprotein2.7.7.490.460
3n65XFJNitric oxide synthase, brain1.14.13.390.460
3os33OSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.460
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.460
4d58BI9Focal adhesion kinase 12.7.10.20.460
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
4ix4ADPUncharacterized protein/0.460
1eetBFUGag-Pol polyprotein2.7.7.490.459
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.459
2bxe1FLSerum albumin/0.459
2q641UNGag-Pol polyprotein3.4.23.160.459
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.459
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3a62STURibosomal protein S6 kinase beta-12.7.11.10.459
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3r28XA0Cyclin-dependent kinase 22.7.11.220.459
4ktc1X3Genome polyprotein3.4.21.980.459
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.459
1kijNOVDNA gyrase subunit B/0.458
1pf9ADP60 kDa chaperonin/0.458
1sh9RITGag-Pol polyprotein3.4.23.160.458
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4g170VNCasein kinase I isoform gamma-32.7.11.10.458
5c8yACPTubulin tyrosine ligase/0.458
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.457
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.457
3qw2NADMyo-inositol-1-phosphate synthase (Ino1)/0.457
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.457
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4hgt15GCasein kinase I isoform delta2.7.11.10.457
4hni16WCasein kinase I isoform epsilon2.7.11.10.457
4i22IREEpidermal growth factor receptor2.7.10.10.457
4xjxATPType I restriction enzyme EcoR124II R protein3.1.21.30.457
5dpvSKEAurora kinase A2.7.11.10.457
5j4eFMNSensory box protein/0.457
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.456
2iw84SPCyclin-dependent kinase 22.7.11.220.456
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.456
4fkpLS5Cyclin-dependent kinase 22.7.11.220.456
4hge15VTyrosine-protein kinase JAK2/0.456
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.456
5auwQUEDeath-associated protein kinase 12.7.11.10.456
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.455
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2xyeCXGGag-Pol polyprotein/0.455
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.455
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.455
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.455
4ix5ANPUncharacterized protein/0.455
4ix6ADPUncharacterized protein/0.455
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.455
4nka2K7Fibroblast growth factor receptor 1/0.455
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
9hvp0E9Gag-Pol polyprotein/0.455
3reyXACAdenosine receptor A2a/0.455
1b38ATPCyclin-dependent kinase 22.7.11.220.454
1csnATPCasein kinase I homolog 12.7.11.10.454
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.454
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1xjdSTUProtein kinase C theta type2.7.11.130.454
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.454
2acxANPG protein-coupled receptor kinase 62.7.11.160.454
2j0m4STFocal adhesion kinase 12.7.10.20.454
2pwlACPFibroblast growth factor receptor 2/0.454
2xclANPPhosphoribosylamine--glycine ligase/0.454
3gc8B45Mitogen-activated protein kinase 112.7.11.240.454
3mqe416Prostaglandin G/H synthase 21.14.99.10.454
3mv5XFERAC-alpha serine/threonine-protein kinase2.7.11.10.454
3pe2E1BCasein kinase II subunit alpha2.7.11.10.454
3ztxZTXAurora kinase B-A2.7.11.10.454
4grb0XGCasein kinase II subunit alpha2.7.11.10.454
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.454
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.454
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.453
1svmATPLarge T antigen3.6.40.453
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.453
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.453
2btsU32Cyclin-dependent kinase 22.7.11.220.453
2h96893Mitogen-activated protein kinase 82.7.11.240.453
2pd7FADVivid PAS protein VVD/0.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
2xru400Aurora kinase A2.7.11.10.453
3qtwX3ACyclin-dependent kinase 22.7.11.220.453
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4ehv0SJMitogen-activated protein kinase 14/0.453
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.453
4k33ACPFibroblast growth factor receptor 32.7.10.10.453
4o0wADNAurora kinase A2.7.11.10.453
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.453
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1ouy094Mitogen-activated protein kinase 14/0.452
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.452
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.452
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.452
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.452
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3nynSGVG protein-coupled receptor kinase 62.7.11.160.452
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.452
4btkDTQTau-tubulin kinase 12.7.11.10.452
4ej7ATPAminoglycoside 3'-phosphotransferase AphA1-IAB/0.452
4eyjN61Mitogen-activated protein kinase 132.7.11.240.452
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.452
4nm9FADBifunctional protein PutA/0.452
5av3KMPDeath-associated protein kinase 12.7.11.10.452
1i59ADPChemotaxis protein CheA2.7.13.30.451
1n07FMNRiboflavin kinase2.7.1.260.451
1nmdATPMajor actin/0.451
1zg32HIIsoflavone 4'-O-methyltransferase/0.451
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2gn9UPGUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.451
2hiw7MPTyrosine-protein kinase ABL12.7.10.20.451
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.451
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.451
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.451
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.451
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.451
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.451
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.451
1h1r6CPCyclin-dependent kinase 22.7.11.220.450
1q3sADPThermosome subunit alpha/0.450
1rgiATPActin, alpha skeletal muscle/0.450
1u54ACPActivated CDC42 kinase 1/0.450
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2pym1UNGag-Pol polyprotein3.4.23.160.450
2x6dX6DAurora kinase A2.7.11.10.450
3ctj320Hepatocyte growth factor receptor2.7.10.10.450
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.450
3rkb12ZCyclin-dependent kinase 22.7.11.220.450
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.450
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.450
4pkiATPActin, alpha skeletal muscle/0.450
4yuqKS1Calmodulin-like domain protein kinase/0.450
4z69DIFSerum albumin/0.450
5dr9SKEAurora kinase A2.7.11.10.450
5e8ySTUTGF-beta receptor type-22.7.11.300.450
1jlcFTCGag-Pol polyprotein2.7.7.490.449
1tv8SAMGTP 3',8-cyclase4.1.99.180.449
1wvxBD4Death-associated protein kinase 12.7.11.10.449
2cppCAMCamphor 5-monooxygenase1.14.15.10.449
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.449
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.449
2pvmP29Casein kinase II subunit alpha2.7.11.10.449
2vgoAD5Aurora kinase B-A2.7.11.10.449
2y9qANPMitogen-activated protein kinase 12.7.11.240.449
3bu5ATPInsulin receptor2.7.10.10.449
3buzLARActin, alpha skeletal muscle/0.449
3fzsB96Protein-tyrosine kinase 2-beta2.7.10.20.449
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.449
3icsCOACoenzyme A disulfide reductase/0.449
3m6gLO3Actin, alpha skeletal muscle/0.449
3qzgX67Cyclin-dependent kinase 22.7.11.220.449
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.449
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.449
3zewSTUEphrin type-B receptor 42.7.10.10.449
4bgg844Activin receptor type-12.7.11.300.449
4f630S7Fibroblast growth factor receptor 1/0.449
4hvh19RTyrosine-protein kinase JAK32.7.10.20.449
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.449
1fvt106Cyclin-dependent kinase 22.7.11.220.448
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.448
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.448
2chlDKICasein kinase I isoform gamma-32.7.11.10.448
2itzIREEpidermal growth factor receptor2.7.10.10.448
2r43G3GGag-Pol polyprotein3.4.23.160.448
2x1nX1NCyclin-dependent kinase 22.7.11.220.448
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.448
3bqr4RBDeath-associated protein kinase 3/0.448
3ekt017Gag-Pol polyprotein3.4.23.160.448
3gubGUBDeath-associated protein kinase 12.7.11.10.448
3hllI45Mitogen-activated protein kinase 14/0.448
3m9vTYDFAD-dependent oxidoreductase/0.448
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.448
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
3vvh4BMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.448
4be7ATPType I restriction enzyme EcoR124II R protein3.1.21.30.448
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.448
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.448
4fuxE75Mitogen-activated protein kinase 12.7.11.240.448
4hyu1BKMitogen-activated protein kinase 82.7.11.240.448
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.448
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.448
5aaaVGHALK tyrosine kinase receptor2.7.10.10.448
5auzGENDeath-associated protein kinase 12.7.11.10.448
5dr6SKEAurora kinase A2.7.11.10.448
1cm8ANPMitogen-activated protein kinase 12/0.447
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.447
1lhvNOGSex hormone-binding globulin/0.447
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.447
1rc4DDFDihydrofolate reductase1.5.1.30.447
2b55D31Cyclin-dependent kinase 22.7.11.220.447
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.447
2btrU73Cyclin-dependent kinase 22.7.11.220.447
2dcnADP2-keto-3-deoxy-gluconate kinase/0.447
2izrBRKCasein kinase I isoform gamma-32.7.11.10.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
2uzeC95Cyclin-dependent kinase 22.7.11.220.447
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.447
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.447
3dxmN24Actin-related protein 3/0.447
3js2VM1Fibroblast growth factor receptor 1/0.447
3pehIBDEndoplasmin homolog, putative/0.447
3qtsX46Cyclin-dependent kinase 22.7.11.220.447
3rm618ZCyclin-dependent kinase 22.7.11.220.447
3rm719ZCyclin-dependent kinase 22.7.11.220.447
3s1cZIRCytokinin dehydrogenase 11.5.99.120.447
3tl9ROCGag-Pol polyprotein3.4.23.160.447
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.447
4jrvKJVEpidermal growth factor receptor2.7.10.10.447
4ldkFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.447
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.447
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.447
4r7iSTIMacrophage colony-stimulating factor 1 receptor2.7.10.10.447
4wsqKSAAP2-associated protein kinase 12.7.11.10.447
4xdmGDMHeat shock cognate 90 kDa protein/0.447
1dyjDDFDihydrofolate reductase1.5.1.30.446
2aazCB3Thymidylate synthase2.1.1.450.446
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.446
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.446
2w05FRTCyclin-dependent kinase 22.7.11.220.446
3bheBZNGag-Pol polyprotein3.4.23.160.446
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
3gu7ADPDeath-associated protein kinase 12.7.11.10.446
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4becATPType I restriction enzyme EcoR124II R protein3.1.21.30.446
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.446
4fyn0VETyrosine-protein kinase SYK2.7.10.20.446
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
4jx1CAMCamphor 5-monooxygenase1.14.15.10.446
5auxKMPDeath-associated protein kinase 12.7.11.10.446
5awmANPStress-activated protein kinase JNK2.7.11.240.446
5ifyTRHGlucose-1-phosphate thymidylyltransferase/0.446
3rfmCFFAdenosine receptor A2a/0.446
1a71NADAlcohol dehydrogenase E chain1.1.1.10.445
1fq1ATPCyclin-dependent kinase 22.7.11.220.445
1hnvTBOGag-Pol polyprotein2.7.7.490.445
1hvsA77Gag-Pol polyprotein/0.445
1j39UPGDNA beta-glucosyltransferase/0.445
1jstATPCyclin-dependent kinase 22.7.11.220.445
1k2c0Q4Gag-Pol polyprotein3.4.23.160.445
1nzdUPGDNA beta-glucosyltransferase/0.445
1py5PY1TGF-beta receptor type-12.7.11.300.445
1sdtMK1Gag-Pol polyprotein3.4.23.160.445
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.445
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1wbwLI4Mitogen-activated protein kinase 14/0.445
2bunFADAppA protein/0.445
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3dy71CXDual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
3iw7IPKMitogen-activated protein kinase 14/0.445
3meeT27Gag-Pol polyprotein2.7.7.490.445
3qwjX6ACyclin-dependent kinase 22.7.11.220.445
3rpv26ZCyclin-dependent kinase 22.7.11.220.445
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4an2EUIDual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.445
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4jboWPHAurora kinase A2.7.11.10.445
4jq7KJQEpidermal growth factor receptor2.7.10.10.445
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.445
4kba1QMCasein kinase I isoform delta2.7.11.10.445
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.445
4lj7MNTChaperone protein ClpB/0.445
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.445
4njt017Protease/0.445
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4tnbSGVG protein-coupled receptor kinase 52.7.11.160.445
4z34ON7Lysophosphatidic acid receptor 1/0.445
3uzcT4EAdenosine receptor A2a/0.445
1a9mU0EGag-Pol polyprotein/0.444
1hpoUNIGag-Pol polyprotein3.4.23.160.444
1hsgMK1Gag-Pol polyprotein/0.444
1jpaANPEphrin type-B receptor 22.7.10.10.444
2bpy3INGag-Pol polyprotein3.4.23.160.444
2bpz3INGag-Pol polyprotein3.4.23.160.444
2c4cFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.444
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.444
2f8g017Gag-Pol polyprotein3.4.23.160.444
2fgiPD1Fibroblast growth factor receptor 1/0.444
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.444
2hc0AB2Protease/0.444
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.444
2idw017Protease/0.444
2izsBRQCasein kinase I isoform gamma-32.7.11.10.444
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.444
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.444
2x3nFADProbable FAD-dependent monooxygenase/0.444
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.444
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.444
2yn8STUEphrin type-B receptor 42.7.10.10.444
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.444
3mtfA3FActivin receptor type-12.7.11.300.444
3negPYVAbscisic acid receptor PYL1/0.444
3s00Z60Cyclin-dependent kinase 22.7.11.220.444
3zy5GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.444
4b1vLABActin, alpha skeletal muscle/0.444
4eok4SPCyclin-dependent kinase 22.7.11.220.444
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.444
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.444
4hw764MMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.444
5aut2ANDeath-associated protein kinase 12.7.11.10.444
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
1h48CDI2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.443
1ivp1ZKGag-Pol polyprotein/0.443
1ivq0PXGag-Pol polyprotein/0.443
1kp8AGS60 kDa chaperonin/0.443
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.443
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.443
1v9aSAHUncharacterized protein/0.443
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
2agvBHQSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
2avm2NCGag-Pol polyprotein3.4.23.160.443
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.443
2etm7PYFocal adhesion kinase 12.7.10.20.443
2hog710Serine/threonine-protein kinase Chk12.7.11.10.443
2i4vDJRV-1 protease/0.443
2x7gPVBSRSF protein kinase 22.7.11.10.443
2yaaATPDeath-associated protein kinase 2/0.443
3at4CCKCasein kinase II subunit alpha2.7.11.10.443
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.443
3ekuATPActin-5C/0.443
3kb0A8SAbscisic acid receptor PYL2/0.443
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.443
3oriAGSSerine/threonine protein kinase/0.443
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.443
3ukuC69Actin-related protein 3/0.443
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4eh90OQMitogen-activated protein kinase 14/0.443
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.443
4fmqANPMitogen-activated protein kinase 12.7.11.240.443
4iwxADPRibosomal protein S6--L-glutamate ligase/0.443
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.443
4l8u9AZSerum albumin/0.443
4l9i8PRRhodopsin kinase/0.443
4otiMI1Serine/threonine-protein kinase N1/0.443
4zgnATPCell division cycle protein 123/0.443
5av047XDeath-associated protein kinase 12.7.11.10.443
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
1zyjBI5Mitogen-activated protein kinase 14/0.442
2qak1UNGag-Pol polyprotein3.4.23.160.442
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
2vwcBC2ATP-dependent molecular chaperone HSP82/0.442
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.442
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.442
3gc7B45Mitogen-activated protein kinase 14/0.442
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.442
3qp0NI8Gag-Pol polyprotein3.4.23.160.442
3qu0X40Cyclin-dependent kinase 22.7.11.220.442
3r6pA8SAbscisic acid receptor PYL10/0.442
3rusADPChaperonin/0.442
3vetADPnebramycin 5' synthase6.1.2.20.442
4asdBAXVascular endothelial growth factor receptor 22.7.10.10.442
4bchT7ZCyclin-dependent kinase 92.7.11.220.442
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.442
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.442
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.442
4fxfATPPyruvate kinase PKM2.7.1.400.442
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1hckATPCyclin-dependent kinase 22.7.11.220.441
1hosPHPGag-Pol polyprotein/0.441
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.441
1mduATPActin, alpha skeletal muscle/0.441
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2fleAIProtease/0.441
2hm9TRRDihydrofolate reductase1.5.1.30.441
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.441
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.441
2z4bDC8Estrogen receptor beta/0.441
3vquO22Dual specificity protein kinase TTK2.7.12.10.441
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.441
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.441
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.441
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.441
4gu94GUFocal adhesion kinase 12.7.10.20.441
4iwyADPRibosomal protein S6--L-glutamate ligase/0.441
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.441
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.441
3uzaT4GAdenosine receptor A2a/0.441
1b6lPI4Gag-Pol polyprotein3.4.23.160.440
1dajMOTDihydrofolate reductase1.5.1.30.440
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1hviA77Protease/0.440
1p4mFMNRiboflavin kinase2.7.1.260.440
1rf9DBRCamphor 5-monooxygenase1.14.15.10.440
1xl2189Gag-Pol polyprotein3.4.23.160.440
2bx8AZQSerum albumin/0.440
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.440
2p3a3TLPol protein/0.440
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.440
2qd7065Gag-Pol polyprotein3.4.23.160.440
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.440
2qi3MZ5Gag-Pol polyprotein/0.440
3c35KAIGlutamate receptor ionotropic, kainate 1/0.440
3c4zADPRhodopsin kinase/0.440
3em6017Gag-Pol polyprotein3.4.23.160.440
3kvxFMYMitogen-activated protein kinase 102.7.11.240.440
3lu7IPXSerum albumin/0.440
3m8p65BGag-Pol polyprotein2.7.7.490.440
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.440
3nbwTR4Ketohexokinase/0.440
3orn3ORDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3swrSFGDNA (cytosine-5)-methyltransferase 12.1.1.370.440
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.440
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.440
4gk3L87Ephrin type-A receptor 32.7.10.10.440
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4jq8KJ8Epidermal growth factor receptor2.7.10.10.440
4y93746Tyrosine-protein kinase/0.440
4ylfFADDihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog/0.440
7upjINUGag-Pol polyprotein3.4.23.160.440
4ej4EJ4Delta-type opioid receptor/0.440